The a16z Show

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1.000 afleveringen, van nieuw naar oud

  1. From Silicon Valley to the Pentagon: The Future of Defense Innovation

    7 maart 2024 · 44 min

    Afspelen
    The last few decades have been a period of transition for defense. An increasing number of startups have begun to rival large defense primes, the industry has gradually become a calculus of both hardware and software, and exponential technologies have forced the DoD to rethink how it has traditionally done business. Lees meer

    These changing conditions were some of the inputs to resulting in the DIU – Defense Innovation Unit – starting in 2015 within the Department of Defense, focused on accelerating the adoption of technology.

    In this episode recorded at a16z’s American Dynamism Summit in January, a16z General Partner Katherine Boyle is joined by the Director of the DIU, Doug Beck, plus two critical founders ushering in this new era of defense: Brian Schimpf, cofounder and CEO of Anduril and Brandon Tseng, cofounder of Shield AI.

    So what does the next wave of defense innovation really look like? Let’s find out.

    00:00 - The Future of Defense Innovation

    03:30 - The Defense Innovation Unit (DIU)

    05:45 - Adoption of Startup tech by the DoD

    07:42 - Acquisition, Budgeting, and Contracting

    13:17 - Traditional Primes vs Startups

    14:25 - Cost-Plus Fixed Fee Contracts

    20:11 - The Replicator Program

    22:26 - The New Threat Environment

    27:11 - Scale and Readiness for Modern Warfare

    32:15 - Procurement Reform and Feasibility

    39:30 - Success Metrics for Defense

    Resources:

    Learn more about AD Summit 2024: www.a16z.com/adsummit

    Watch Brian’s stage talk at AD Summit 2024: https://a16z.com/securing-americas-future-how-technology-companies-and-washington-are-building-a-safer-world/

    Watch all of the stage talks at AD Summit 2024: https://www.youtube.com/playlist?list=PLM4u6XbiXf5pAKmk1AeZ9964KGScf4lHM

    Find Katherine on Twitter: https://twitter.com/KTmBoyle

    Find Brandon and Shield AI on Twitter: https://twitter.com/shieldaitech

    Find Brian on Twitter: https://twitter.com/schimpfbrian

    Find Doug and the DIU on Twitter: https://twitter.com/diu_x

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  2. What is American Dynamism?

    4 maart 2024 · 31 min

    Afspelen
    American Dynamism. A term coined by a16z General Partner, Katherine Boyle, two years ago, when she and David Ulevitch founded the firm's American Dynamism investing practice. Lees meer

    Beyond a sector or movement, American Dynamism embodies innovation, community, and a unique philosophy touching every facet of American life.

    In this episode, we hear from 10 voices, including policymakers, founders, and funders, as they share what American Dynamism means to them. They discuss the critical technologies shaping the future and the challenges on the path to the next decade of dynamism.

    Stay tuned for more exclusive conversations from a16z's second annual American Dynamism Summit in Washington, D.C.

    Resources:

    Find Dr. Kathryn Huff on Twitter: https://twitter.com/katyhuff

    Find Nand Mulchandani on Twitter: https://twitter.com/nandmulchandani

    Find Doug Beck and the DIU on Twitter: https://twitter.com/diu_x

    Find Mitch Lee on Twitter: https://twitter.com/dontmitch

    Find Ian Cinnamon on Twitter: https://twitter.com/IanCinnamon

    Find Doug Bernauer and Radiant on Twitter: https://twitter.com/radiantnuclear

    Find Chris Bennett on Twitter: https://twitter.com/8ennett

    Find Mike Slagh on Twitter: https://twitter.com/MikeSlagh

    Find Rahul Sidhu on Twitter: https://twitter.com/rahoolsidoo

    Find Wyatt Smith on Twitter: https://twitter.com/wyatt_h_smith

    Learn more about American Dynamism: https://a16z.com/american-dynamism

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    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the compa…

  3. The Quest for True Signal: How Zynga Spotted Mobile

    27 februari 2024 · 48 min

    Afspelen
    You might recognize the name Mark Pincus but we almost guarantee you recognize the game Farmville. Lees meer

    Mark Pincus is the founder and longtime CEO of Zynga, known for its massive global franchise of games, including those household names like Farmville and Words with Friends. Zynga was also at the forefront of the transition to mobile and the use of large platforms like Facebook for distribution.

    In this episode Mark joins Josh Lu from the a16z Games team for a fireside chat. They discuss navigating major tech waves and recognizing "true signal" opportunities, and explore a wide range of topics, from the strategic insights that propelled Zynga to success, the future of the Metaverse, and the philosophy behind minimum viable products.

    This conversation offers invaluable insights for both gaming industry insiders and enthusiasts looking to understand the dynamics of tech innovation and entrepreneurship.

    Topics Covered:

    00:00 - How Zynga Spotted the Mobile Wave

    02:47 - Challenges of Starting Zynga

    05:24 - Zynga's Early Workforce and Learning HTML

    07:40 - Preparing for Tech Waves

    11:29 - The Importance of Being Too Early

    15:42 - The attribute of great founders

    18:33 - Hiring Philosophy

    22:02 - ‘Everyone is a CEO’

    24:20 - Fast Iteration and Learning from Failures

    31:06 - Personal Gaming Preferences

    32:52 - Advice on Reevaluating Projects and True Signal

    35:50 - AI's Role in Consumer Adoption and Gaming

    40:17 - Community as a Core Element

    43:31 - UGC Gaming Space and Future Computing Paradigms

    Resources:

    Find Mark on Twitter: https://twitter.com/markpinc

    Find Josh on Twitter: https://twitter.com/joshlu

    Learn more about SPEEDRUN 3.0: https://a16z.com/speedrun3

    Learn more about SPEEDRUN: ttps://a16z.com/speedrun-your-gaming-startup

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    Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

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  4. Beyond Uncanny Valley: Breaking Down Sora

    24 februari 2024 · 35 min

    Afspelen
    In early 2024, the notion of high fidelity, believable AI-generated video seemed a distant future to many. Yet, a mere few weeks into the year, OpenAI unveiled Sora, its new state of the art text-to-video model producing videos of up to 60 seconds. The output shattered expectations – even for other builders and researchers within generative AI – sparking widespread speculation and awe. Lees meer

    How does Sora achieve such realism? And are explicit 3D modeling techniques or game engines at play?

    In this episode of the a16z Podcast, a16z General Partner Anjney Midha connects with Stefano Ermon, Professor of Computer Science at Stanford and key figure at the lab behind the diffusion models now used in Sora, ChatGPT, and Midjourney. Together, they delve into the challenges of video generation, the cutting-edge mechanics of Sora, and what this all could mean for the road ahead.

    Resources:

    Find Stefano on Twitter: https://twitter.com/stefanoermon

    Find Anjney on Twitter: https://twitter.com/anjneymidha

    Learn more about Stefano’s Deep Generative Models course: :

    https://deepgenerativemodels.github.io

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    Subscribe on your favorite podcast app: https://a16z.simplecast.com/

    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

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    Please note that the content here is…

  5. Fraying Wires: The Decentralization of the Electric Grid

    15 februari 2024 · 43 min

    Afspelen
    The electric grid needs an update. Lees meer

    In this explainer, a16z Partner Ryan McEntush discusses the escalating complexity of the grid, unveils its vulnerabilities, and traces the evolutionary path that has led us to this point. From the surging demands of AI to outdated infrastructure, we delve into the potential roles of cutting-edge technologies such as solar batteries, natural gas, and nuclear power in shaping the grid's future.

    Timestamps:

    (00:00) - Introduction

    (02:28) - The Need for Grid Modernization

    (04:43) - Understanding the Grid's Operation and Challenges

    (06:47) - The Complexity of Grid Management

    (08:31) - Increasing Outages and Volatility

    (11:49) - The Role of New Technologies

    (17:53) - The Potential and Limitations of Renewable Energy Sources

    (19:08) - Energy Storage Solutions

    (24:57) - The Future of Natural Gas and Nuclear Power

    (29:46) - The Impact of Policy on the Grid

    (31:47) - The Concept of a Smart Grid

    (34:04) - Decentralization of the Grid

    (36:57) - The Role of the Free Market in Grid Reliability

    Resources:

    Find Ryan on Twitter: https://twitter.com/rmcentush

    Read Ryan’s latest articles: https://a16z.com/author/ryan-mcentush

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    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

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  6. Fixing Higher Education & New Startup Opportunities with Marc and Ben

    8 februari 2024 · 2 uur

    Afspelen
    "The Ben & Marc Show" features a16z's co-founders Ben Horowitz & Marc Andreessen. In this episode, Marc and Ben continue their in-depth exploration of the current education system. While Part I of their discussion unpacked the crisis facing higher education, Part II presents solutions to overhaul the modern university. Lees meer

    In this one-on-one conversation, Ben and Marc delve into actions that existing institutions can take to improve their current and future situations. This includes exploring new methods for talent recruitment, providing a more individualized education experience for students, and reducing administrative bloat. They also apply an entrepreneurial lens to each university function, revealing startup opportunities poised to emerge – including the building of brand new institutions, nonprofits, and research entities. Enjoy!

    Resources:
    *Watch Part I: https://youtu.be/7J2_G4oHRQ0
    *Watch Part II: https://youtu.be/EeIdalo2huI

    Marc on X: https://twitter.com/pmarca
    Marc’s Substack: https://pmarca.substack.com/
    Ben on X: https://twitter.com/bhorowitz
    “South Park” episode mentioned in this discussion: – Eps 1505 (stream on Max): https://bit.ly/3HrZQg0

    Stay Updated:

    Find us on X: https://twitter.com/a16z
    Find us on LinkedIn: https://www.linkedin.com/company/a16z

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    Follow our host: https://twitter.com/eriktorenberg

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and…

  7. Read Write Own: A New Era

    2 februari 2024 · 1 uur 20 min

    Afspelen
    with @cdixon @rhhackett Lees meer

    Welcome to the web3 with a16z crypto podcast. I'm Robert Hackett, an editor here at a16z crypto, and I'm here with Chris Dixon, founding partner of a16z crypto and author of the new book Read Write Own: Building the Next Era of the Internet. I had the privilege of editing Chris throughout the book writing process, and I'm thrilled now to talk to you about what went on behind the scenes, the big themes of the book, the challenges, and also about the crypto industry at large as well as what we can expect from it in the future.

    Learn more at https://readwriteown.com/.

    Resources for references in this episode:

    Black Swan by Nassim Nicholas Taleb

    The Tipping Point by Malcolm Gladwell

    Spider-Man: Across the Spider-verse

    "'It's a canon event' TikTok trend, explained"

    Chris Dixon's blog at cdixon.org

    "Come for the tool, stay for the network"

    "The next big thing starts out looking like a toy"

    "Can't be evil"

    The Cold Start Problem by Andrew Chen

    On Andrew Chen's writing habits

    On investing in Coinbase in 2013

    Guidance from the U.S. Securities & Exchange Commission in 2019: "Framework for 'Investment Contract' Analysis of Digital Assets"

    On blockchains as "a programmable computer that lives in the sky" via a16z crypto head of research Tim Roughgarden

    Gödel Escher Bach by Douglas Hofstader

    "How Aristotle Created the Computer" by Chris Dixon for The Atlantic

    "A Symbolic Analysis of Relay and Switching Circuits" by Claude Shannon

    Principia Mathematica by Bertrand Russell and Alfred North Whitehead

    An Investigation of the Laws of Thought by George Boole

    The End of Education by Neil Postman

    "Inside out vs. outside in: The adoption of new technologies" by Chris Dixon

    "The Inevitable Showdown Between Twitter and Twitter Apps" by Chris Dixon

    "Elon Musk says X is discouraging links in posts" by Sara Fischer

    "Make Ethereum Cypherpunk Again" by Vitalik Buterin

    "What Will Happen in 2024" by Fred Wilson

    "A Logical Calculus of the Ideas …

  8. The What, Who, and When with IPOs

    29 januari 2024 · 34 min

    Afspelen
    In 2022 and 2023, US IPOs hit decade lows after the record high of 2021. Now, in 2024, will the IPO window reopen? Lees meer

    In this episode, we revisit a conversation with Jeff Jordan, former CEO of OpenTable, and J.D. Moriarty, the former Head Managing Director and Head of Equity Capital Markets at Bank of America Merrill Lynch.

    Joined by Sonal Choksi, the pair takes you behind the scenes to unravel the complexities surrounding IPOs, including pricing, allocations, and the elusive "pop." They also discuss OpenTable’s IPO, which occurred immediately following the worst financial crisis since the Great Depression, and weigh in on the question: Can you time an IPO in an unpredictable year?

    Resources:

    Find Jeff on Twitter: https://twitter.com/jeff_jordan

    Find J.D on LinkedIn: https://www.linkedin.com/in/jdmoriarty

    Find Sonal on Twitter: https://twitter.com/smc90

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    Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

    Subscribe on your favorite podcast app: https://a16z.simplecast.com/

    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

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    Follow our host: https://twitter.com/eriktorenberg

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and …

  9. Jobs of the Future

    24 januari 2024 · 41 min

    Afspelen
    (00:00) - The Future of Jobs Lees meer

    (03:15) - Job growth over the last 80 years

    (05:06) - The shelf-life of jobs

    (09:11) - Education trends

    (12:25) - The importance of learning the foundations

    (17:18) - Regional access to education

    (20:19) - How companies are hiring and looking at strategic priorities

    (22:58) - The economic mobility and economic stability of degrees

    (25:59) - Job and training trends at Grow with Google

    (28:11) - Do companies train or hire for skills?

    (29:23) - The future of the traditional degree

    (31:10) - The employer and educator ecosystem

    (35:36) - How to approach upskilling

    In a world where technology is moving at an unprecedented pace, what will the jobs of the future look like?

    Kai Roemmelt, CEO of the online learning platform Udacity, and Lisa Gevelber, a key figure at Google responsible for building the Grow with Google program, unpack the seismic changes reshaping the tech and education realms.

    From disrupting hiring norms to redefining how we acquire degrees and engage globally, this episode poses the question: How can you skillfully navigate the challenges and seize the opportunities awaiting in this evolving landscape?

    Resources:

    Find Kai on LinkedIn: https://www.linkedin.com/in/kai-roemmelt

    Find Lisa on LinkedIn: https://www.linkedin.com/in/lisagevelber

    Learn more about Udacity: https://www.udacity.com

    Learn more about Grow with Google: https://grow.google

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    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies…

  10. Introducing Raising Health: Fireside Chat with Sean Duffy

    18 januari 2024 · 34 min

    Afspelen
    Big news from a16z: Bio Eats World, our sibling show from a16z Bio+Health, is now Raising Health! Lees meer

    We’re excited to share Raising Health’s first episode here where Sean Duffy, cofounder and CEO of Omada Health, joins Vijay Pande, founding general partner of Bio + Health.

    Sean and Vijay discuss the building and growth of Omada, from the early days to now. As the cofounder of one of the original digital health companies, Sean has unique insight into the growth of both the digital health field and the changing venture capital environment. They also talk about the future of AI, how Omada is leveraging AI, and the challenges that might arise with using a technology in a caregiving environment.

    You can listen to more episodes of Raising Health here: https://link.chtbl.com/IqBoJ2By?sid=a16z11824

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    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

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  11. Crisis in Higher Ed & Why Universities Still Matter with Marc & Ben

    14 januari 2024 · 1 uur 48 min

    Afspelen
    In this one-on-one conversation, Marc and Ben tackle the university system – what has certainly been a hot topic that’s been dominating the news over the past few months. As Marc states at the top of the episode, universities matter tremendously to our world, but they’re currently in a state of crisis. Lees meer

    Together, Ben and Marc take a “structural” look at higher education, delving deep into the twelve functions of the modern university. They also unpack the numerous challenges that universities face today – student debt and the replication crisis, among them.

    They also discuss topics including DEI, student athlete admissions, accreditation, inflation, and much more.

    As colleges face an existential threat that could have long lasting repercussions, how can we find ways to improve these institutions, while being open to new entrepreneurial opportunities in education?

    Check out the Ben and Marc show: https://link.chtbl.com/benandmarc

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    Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

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    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

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    Follow our host: https://twitter.com/eriktorenberg

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not…

  12. Drones, Data, and Deterrence: Technology's Role in Public Safety

    10 januari 2024 · 34 min

    Afspelen
    Flock is a public safety technology platform that operates in over 4,000 cities across the United States, and solves about 2,200 crimes daily. That’s 10 percent of reported crimes nationwide. Lees meer

    Taken from a16z’s recent LP Summit, a16z General Partner David Ulevitch joins forces with Flock Safety’s founder, Garrett Langley and Sheriff Kevin McMahill of the Las Vegas Metropolitan Police Department. Together, they cover the delicate balance between using technology to combat crime and respecting individual privacy, and explore the use of drones and facial recognition, building trust within communities, and the essence of objective policing.

    Resources:

    Find Garret on Twitter: https://twitter.com/glangley

    Find Sheriff McMahill on Twitter: https://twitter.com/Sheriff_LVMPD

    Find David on Twitter:https://twitter.com/davidu

    Learn more about Flock Safety: https://www.flocksafety.com

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    Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

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    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

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    Follow our host: https://twitter.com/eriktorenberg

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any…

  13. DNA's Potential to Store the World's Data

    5 januari 2024 · 21 min

    Afspelen
    Nature’s blueprint – DNA – is an incredibly efficient machine. You cannot see it with the naked eye, yet it can last for hundreds, maybe even millions of years. Plus, the storage capacity of a single gram of DNA is over 200 million gigabytes! As the cost of DNA sequencing (reading) and synthesis (writing) comes down, scientists are looking to our very own biology for applications reaching as far as data storage. Learn more about this fascinating world with a16z General Partner Vijay Pande, as he says, this next wave of biological computing will “be the mother of many new exponentials to come.” Lees meer

    Resources:

    Save As: DNA Part 1: https://exo.substack.com/p/saving-our-story-in-dna-part-1

    Save As: DNA Part 1: https://exo.substack.com/p/save-as-dna-part-2

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    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

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    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/dis…

  14. A Year of Unlocks: 2023 In AI, Healthcare, Housing, and More

    31 december 2023 · 1 uur

    Afspelen
    As we close off 2023, we wanted to revisit some of our favorite episodes from the last year. From AI hardware, to healthcare regulation, to disrupting the world’s largest asset class, to the electrification of nearly everything… there’s something in here for all listeners. Lees meer

    Resources:

    AI Hardware, Explained:

    https://a16z.simplecast.com/episodes/ai-hardware-explained

    Chasing Silicon: The Race for GPUs: https://a16z.simplecast.com/episodes/chasing-silicon-the-race-for-gpus

    The True Cost of Compute: https://a16z.simplecast.com/episodes/the-cost-of-compute

    AI Revolution: Disruption, Alignment, and Opportunity: https://a16z.simplecast.com/episodes/ai-revolution-disruption-alignment-and-opportunity

    The Robot Lawyer Resistance; https://a16z.simplecast.com/episodes/the-robot-lawyer-resistance

    The Quest for AGI: Q*, Self-Play, and Synthetic Data: https://a16z.simplecast.com/episodes/the-quest-for-agi-q-self-play-and-synthetic-data

    The Road to Autonomous Vehicles: Are We There Yet?: https://a16z.simplecast.com/episodes/the-road-to-autonomous-vehicles-are-we-there-yet-PstZz2G_

    The Electrification of Everything: From Sky to Sea: https://a16z.simplecast.com/episodes/the-electrification-of-everything-from-sky-to-sea

    When Two Giants Intersect: Healthcare Meets Fintech: https://a16z.simplecast.com/episodes/when-two-giants-intersect-healthcare-meets-fintech

    Salary Transparency: Clarity or Chaos?: https://a16z.simplecast.com/episodes/salary-transparency-clarity-or-chaos

    Disrupting the World’s Largest Asset Class with Adam Neumann: https://a16z.simplecast.com/episodes/disrupting-the-worlds-largest-asset-class

    The Data Highway Above with Privateer’s Steve Wozniak, Alex Fielding, and Dr. Moriba Jah: https://a16z.simplecast.com/episodes/new-the-data-highway-above-with-privateers-steve-wozniak-alex-fielding-and-dr-moriba-jah

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    Subscribe on your favorite…

  15. The Future of Longevity with Tony Robbins

    26 december 2023 · 1 uur 22 min

    Afspelen
    Welcome to “The Ben & Marc Show”, featuring a16z’s co-founders Ben Horowitz and Marc Andreessen. In this week’s episode, Marc and Ben are joined by special guest Tony Robbins to discuss the future of longevity. Lees meer

    Tony Robbins is an entrepreneur, #1 NY Times bestselling author, philanthropist, and the nation’s #1 life & business strategist. For over four and a half decades, Tony has empowered more than 50 million people from 100 countries around the world through his audio programs, educational videos, and live seminars. He’s also the author of six international bestsellers, including “Money: Master the Game” (2014), “Unshakable: Your Financial Freedom Playbook” (2017) and “Life Force: How New Breakthroughs in Precision Medicine Can Transform the Quality of Your Life and Those You Love” (2022).

    Joined by a16z’s own Dr. Vijay Pande, PhD – General Partner since 2014, and founder and leader of a16z Bio + Health – the group discusses new breakthroughs in regenerative medicine, AI, biohacking, gene editing, mindset and confirms why this might be the best time to be alive. Enjoy!

    Watch the full video version of this episode: https://youtu.be/V8h11baC_ok

    Resources:

    Marc on X: https://twitter.com/pmarca

    Marc’s Substack: https://pmarca.substack.com/

    Ben on X: https://twitter.com/bhorowitz

    Dr. Vijay Pande on X: https://twitter.com/vijaypande

    Learn more about Tony Robbins: https://tonyrobbins.com

    Tony’s Time to Rise Summit (Jan 25-27, 2024): https://timetorisesummit.com/join-now

    Pre-order Tony’s upcoming book “The Holy Grail of Investing” (Feb 2024): http://theholygrailofinvesting.com

    Stay Updated:

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    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be u…

  16. 2024 Big Ideas: Developer Influence, Maritime Upgrades, and New Video Intelligence

    22 december 2023 · 47 min

    Afspelen
    A new age of maritime exploration, the rise of the developer as a buyer in financial services, and more applications for computer vision and video intelligence. We asked over 40 partners across a16z to preview one big idea they believe will drive innovation in 2024. Lees meer

    Here in our 3-part series, you’ll hear directly from partners across all our verticals, as we dive even more deeply into these ideas. What’s the why now? Who is already building in these spaces? What opportunities and challenges are on the horizon? And how can you get involved?

    Topics Covered:

    00:00 - Big Ideas in Tech 2024

    01:39 - Big Idea: The Rise of the Developer as a Buyer in Financial Services

    07:03 - Examples of financial service infrastructure products

    08:40 - Building products and cost/selling structures

    09:56 - How financial institutions will adopt new technology

    13:07 - Regulatory shifts and updates

    14:09 - The impact on customers

    16:30 - Big Idea: A New Age of Maritime

    18:15 - The challenges of maritime exploration

    19:56 - Why is 2024 the year of iInnovation in maritime exploration?

    23:32 - Space and aerospace exploration’s impact on maritime

    26:51 - Geopolitical supply chain and climate applications

    29:40 - Autonomous fleets

    31:49 - Key challenges in modernizing maritime

    34:11 - Opportunities for builders in the space

    36:23 - Big Idea: New Applications for Computer Vision and Video Intelligence

    38:06 - The current use of video and it’s data

    38:53 - The unlocks in hardware and software driving change

    41:40 - Emerging applications and use cases

    43:20 - Video and privacy

    44:49 - Why is 2024 the year of change and innovation?

    Resources:

    Find Angela on Twitter :https://twitter.com/astrange

    Find Grant on Twitter: https://twitter.com/grant__gregory

    Find Kimberly on Twitter: https://twitter.com/kimberlywtan

    View all 40+ big ideas: https://a16z.com/bigideas2024

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  17. Text to Video: The Next Leap in AI Generation

    20 december 2023 · 33 min

    Afspelen
    General Partner Anjney Midha explores the cutting-edge world of text-to-video AI with AI researchers Andreas Blattmann and Robin Rombach. Lees meer

    Released in November, Stable Video Diffusion is their latest open-source generative video model, overcoming challenges in size and dynamic representation.

    In this episode Robin and Andreas share why translating text to video is complex, the key role of datasets, current applications, and the future of video editing.

    Topics Covered:

    00:00 - Text to Video: The Next Leap in AI Generation

    02:41 - The Stable Diffusion backstory

    04:25 - Diffusion vs autoregressive models

    06:09 - The benefits of single step sampling

    09:15 - Why generative video?

    11:19 - Understanding physics through AI video

    12:20 - The challenge of creating generative video

    15:36 - Data set selection and training

    17:50 - Structural consistency and 3D objects

    19:50 - Incorporating LoRAs

    21:24 - How should creators think about these tools?

    23:46 - Open challenges in video generation

    25:42 - Infrastructure challenges and future research

    Resources:

    Find Robin on Twitter: https://twitter.com/robrombach

    Find Andreas on Twitter: https://twitter.com/andi_blatt

    Find Anjney on Twitter: https://twitter.com/anjneymidha

    Stay Updated:

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    Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

    Subscribe on your favorite podcast app: https://a16z.simplecast.com/

    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

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  18. 2024 Big Ideas: Voice-First Apps, AI Moats, Never-Ending Games, and Anime Takes Off

    15 december 2023 · 1 uur 1 min

    Afspelen
    Voice-First Apps, AI Moats, Never-Ending Games, and Anime. We asked over 40 partners across a16z to preview one big idea they believe will drive innovation in 2024. Lees meer

    Here in our 3-part series, you’ll hear directly from partners across all our verticals, as we dive even more deeply into these ideas. What’s the why now? Who is already building in these spaces? What opportunities and challenges are on the horizon? And how can you get involved?

    Timecodes:

    00:00 - Big Ideas in Tech 2024

    01:39 - Big Idea: Voice-First Apps Will Become Integral to Our Lives

    04:14 - The limiting factors of voice technology

    05:27 - What would a voice-first app look like?

    06:52 - Voice tech for companionship and productivity

    08:05 - The primary modality voice applications

    10:08 - How builders and founders can integrate voice technology

    13:31 - Big Idea: The Consumer AI Battleground Moves from Model to UX

    15:49 - How user experience can contribute toward building a moat

    17:57 - The commoditization of models

    19:55 - How should builders differentiate between model and experience?

    22:58 - Breakout examples for 2024

    25:10 - Open source vs closed source

    26:44 - The impact of applications splitting from the infrastructure layer

    28:14 - Big Idea: AI-First Games That Never End

    29:59 -Generative AI in gaming and AI native games

    31:12 - Introducing generative agents as game companions

    33:57 - Does the gaming community want hyper personalization?

    38:00 - New entrants vs the incumbents

    41:57 - How business models and cost structures are evolving

    46:21 - Advice for game builders in 2024

    48:03 - Big Idea: Anime Games Go Mainstream

    49:28 - What defines anime?

    52:05 - Anime’s monetization strategy and how it differs from other genres

    54:04 - Why are we seeing a rise in anime?

    55:56 - What is required to be successful in anime

    58:20 - AI, XR and inventing the next wave of anime

    Resources:

    View all 40+ big ideas: https://a16z.com/bigideas2024

    Stay Updated:

    Find a16z on Twitter: h…

  19. Safety in Numbers: Keeping AI Open

    11 december 2023 · 35 min

    Afspelen
    Arthur Mensch is the co-founder of Mistral and the co-author of Deepmind’s pivotal 2022 "Chinchilla" paper. Lees meer

    In September 2023, Mistral released Mistral-7B, an advanced open-source language model that has rapidly become the top choice for developers. Just this week, they introduced a new mixture of experts model – Mixtral — that’s already generating significant buzz among AI developers.

    As the battleground around large language models heats up, join us for a conversation with Arthur as he sits down with a16z General Partner Anjney Midha. Together, they delve into the misconceptions and opportunities around open source; the current performance reality of open and closed models; and the compute, data, and algorithmic innovations required to efficiently scale LLMs.

    Resources:

    Find Arthur on Twitter: https://twitter.com/arthurmensch

    Find Anjney on Twitter: https://twitter.com/anjneymidha

    Learn more about Mistral: https://mistral.ai

    Learn why we invested in Mistral: https://a16z.com/announcement/investing-in-mistral/

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    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

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    Please note that the content here is for informational purposes only; should NOT be taken as legal, business,…

  20. 2024 Big Ideas: Miracle Drugs, Programmable Medicine, and AI Interpretability

    8 december 2023 · 1 uur 5 min

    Afspelen
    Smart energy grids. Voice-first companion apps. Programmable medicines. AI tools for kids. We asked over 40 partners across a16z to preview one big idea Lees meer

    they believe will drive innovation in 2024.

    Here in our 3-part series, you’ll hear directly from partners across all our verticals, as we dive even more deeply into these ideas. What’s the why now? Who is already building in these spaces? What opportunities and challenges are on the horizon? And how can you get involved?

    View all 40+ big ideas: https://a16z.com/bigideas2024

    Stay Updated:

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    Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

    Subscribe on your favorite podcast app: https://a16z.simplecast.com/

    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

    Stay Updated:

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    Follow our host: https://twitter.com/eriktorenberg

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

  21. The Quest for AGI: Q*, Self-Play, and Synthetic Data

    4 december 2023 · 27 min

    Afspelen
    One topic at the center of the AI universe this week is a potential breakthrough called Q*. Little has been revealed about this OpenAI project, other than its likely relationship to solving certain grade-school mathematical problems. Lees meer

    Amid much speculation, we decided to bring in our new general partner, Anjney Midha – focused on all things AI – to sift through the sea of noise.

    Today, we discuss the key frontier research areas that AI labs are exploring on their path toward generalizable intelligence, from self-play, to model-free reinforcement learning to synthetic data. Anjney also shares his insights on which approach he expects to be most influential in the next wave of LLMs and why math problems are even a suitable testing ground for this kind of research.

    Topics Covered:

    02:03 - What is Q*?

    06:21 - Applying model-free reinforcement learning to complex spaces

    13:17 - The role of self-play

    19:04 - Synthetic data’s big unlock

    24:44 - What does this unlock for society?

    Resources:

    Follow Anjney on Twitter: https://twitter.com/AnjneyMidha

    Stay Updated:

    Find a16z on Twitter: https://twitter.com/a16z

    Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

    Subscribe on your favorite podcast app: https://a16z.simplecast.com/

    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

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    Follow our host: https://twitter.com/eriktorenberg

    Please note that the content here is for informational purposes only; should N…

  22. Financial Freedom, Company Building, More with David Marcus

    28 november 2023 · 49 min

    Afspelen
    with @davidmarcus @smc90 Lees meer

    This wide-ranging conversation covers company building, big to small -- including what cadence and when is the right "time" to ship; the relationship between centralization, decentralization, platforms, and financial freedom; moving from web2 to web3 in both crypto AND payments... as well as why bitcoin, views on remote work, and much much more.

    Our guest is David Marcus, CEO and co-founder of Lightspark; Marcus was also a co-creator of Diem (aka Libra and Novi, the cryptocurrency project initiated by Facebook). Before that, he was vice president of messaging products there, where he ran the Facebook Messenger unit; and prior to joining Facebook, Marcus was the former president of PayPal (which had acquired his previous startup).

    This episode begins with an interview just to help kick things off and then features a rich set of questions from the audience -- as this originally took place live on stage at our Crypto Startup School 2023.

    As a reminder: none of this should be taken as investment, legal, business, or tax advice; please see a16z.com/disclosures for more important information -- including a link to a list of our investments.

    related readings:

    Regulate apps, not protocols series (2022-2023) - Miles Jennings et al, a16z crypto)

    What it will take to create the next great Silicon Valleys (2014) - Marc Andreessen (Politico, a16z)

    Why bitcoin matters (2014) - Marc Andreeessen (NYT, a16z)

    When one app rules them all: The case of WeChat and Mobile in China (2015) - Connie Chan (a16z)

    Subscribe to web3 with a16z: https://link.chtbl.com/web3witha16z

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    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be…

  23. When Business is Battle: Inside the Boardrooms of the CEOs that Survived the Storm

    23 november 2023 · 51 min

    Afspelen
    Taking a company from idea to household name is always difficult. But the past few years presented challenges that caught even the most-seasoned CEOs off guard. Lees meer

    In this episode, you’ll hear from two CEOs that navigated these waters and somehow, came out on the other side. These recordings come straight from our exclusive Connect/Enterprise event, bringing together top executives across the a16z network.

    Resources:

    Additional content from Connect/Enteprise:

    Enterprise Startups: Advice on Hiring, Firing, Scaling, and Selling

    Building Products With Generative AI

    Learn more about company-building: https://a16z.com/category/company-building/

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    Subscribe on your favorite podcast app: https://a16z.simplecast.com/

    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

    Stay Updated:

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    Follow our host: https://twitter.com/eriktorenberg

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection …

  24. The Worlds She Sees with Godmother of AI, Fei-Fei Li

    13 november 2023 · 28 min

    Afspelen
    Fei-Fei Li, PhD, Professor in the Computer Science Department at Stanford University, and Co-Director of Stanford’s Human-Centered AI Institute, joins Bio + Health founding partner Vijay Pande. Lees meer

    In this candid conversation, Li unfolds her transformation from a young immigrant to an influential figure in AI. The conversation explores the birth of ImageNet, a pivotal step that bridged the gap between visual intelligence and accessible AI technology. They delve into the notion of a 'Dignity Economy,' hinting at a future where technology serves to elevate human experience rather than undermine it. Li also touches on the delicate balance between relentless innovation and life's humble pursuits. This episode peels back the layers on the human side of AI, offering a rare glimpse into the personal and professional realms of a pioneer shaping the AI landscape.

    Check out her new book, The Worlds I See, here: https://us.macmillan.com/books/9781250897930/theworldsisee

    Check out other episodes form our sister podcast, Bio Eats World: https://a16z.com/podcasts/bio-eats-world/

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    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

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    Please note that the content here is for informational purpose…

  25. From Sims to Sapiens: Crafting Reality with Code

    6 november 2023 · 39 min

    Afspelen
    Is it possible to construct a virtual society that authentically replicates human behavior? AI Town, a virtual town experiment where AI residents live, interact, and engage, provides valuable insights into the future of AI's believability and its interaction with humanity. Lees meer

    In this panel discussion, Joon Park, the author of 'Generative Agents: Interactive Simulacra of Human Behavior,' and Martin Casado from a16z, discuss the influence and potential of Generative Agents, exploring their practical applications in the real world.

    Topics Covered

    00:00 - Simulating human behaviors

    04:49 - What are generative agents?

    07:47 - Simulations, new technology, and LLMs

    11:45 - The architecture behind simulating human behavior

    16:37 - Generative agents interactions: observing, planning, and reflecting

    20:22 - What is the value in advancing generative agents?

    24:01 - Use cases for simulation behavior technology

    29:31 - What are the ethical frameworks?

    33:12 - Q&A from the audience

    Resources:

    Find AI Town: https://www.convex.dev/ai-town

    Read the paper ‘Generative Agents: Interactive Simulacra of Human Behavior’: https://arxiv.org/pdf/2304.03442.pdf

    Find Joon on Twitter: https://twitter.com/joon_s_pk

    Find Martin on Twitter: https://twitter.com/martin_casado

    Find a16z on Twitter: https://twitter.com/a16z

    Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

    Subscribe on your favorite podcast app: https://a16z.simplecast.com/

    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

    Stay Updated:

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  26. Fintech Fuels Global Payments

    30 oktober 2023 · 40 min

    Afspelen
    Software crosses borders effortlessly. The globalization of money, however, is considerably more challenging. This is especially true for multinational businesses, which grapple with managing multiple accounts in diverse currencies, navigating costly foreign exchange rates, and unpredictable money transfers. Lees meer

    As businesses increasingly embrace a global default, top fintech entrepreneurs are rising to the challenge, addressing cross-border infrastructure issues and offering comprehensive solutions.

    In this episode, a16z partners Angela Strange, Joe Schmidt, and Gabriel Vasquez discuss the challenges of cross-border payment infrastructures and what fintech entrepreneurs are doing to create a more integrated, financially inclusive world.

    Topics Covered:

    00:00 - Software crosses borders easily; money does not.

    03:02 - Why has global payments been a challenge for so long?

    05:44 - How global payments and money currently moves

    07:25 - The metrics used to measure a country's financial health

    12:13 - The impact of regulation on financial services

    16:23 - Can the same regulations be applied to any country?

    21:29 - Why each country has its own fintech system

    24:54 - Opportunities in global payments infrastructure

    34:47 - Advice for founders navigating global fintech systems

    36:58 - What does a truly global system enable?

    Read the Fintech Fuels Global Payments package: https://a16z.com/global-payments

    Watch ​​’Foreign Exchange 101: What Happens When You Send Money Abroad?’: https://youtu.be/eoXdyO9oGJc?feature=shared

    Find Angela on Twitter: https://twitter.com/astrange

    Find Joe Schmidt on Twitter: https://twitter.com/joeschmidtiv

    FInd Gabriel Vasquez on Twitter: https://twitter.com/GEVS94

    Stay Updated:

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    Please note that the content …

  27. The Techno-Optimist Manifesto with Marc Andreessen and Ben Horowitz

    25 oktober 2023 · 1 uur 7 min

    Afspelen
    Subscribe to The Ben & Marc Show on Apple Podcasts: https://bit.ly/3SdsfNt Lees meer

    Subscribe to The Ben & Marc Show on Spotify: https://spoti.fi/3SclPOr

    Read the full manifesto: https://a16z.com/the-techno-optimist-manifesto/

    This past week, Marc released his new vision for the future – “The Techno-Optimist Manifesto”.

    In an article that has sparked widespread conversation across traditional and social media, Marc challenges the pessimistic narrative surrounding technology today, and instead celebrates it as a liberating force that can lead to growth, progress and abundance for all. In this one-on-one conversation based on YOUR questions from X (formerly Twitter), Ben and Marc discuss how technological advancements can improve the quality of human life, uplift marginalized communities, and even encourage us to answer the bigger questions of the universe.

    We hope you’ll be inspired to join us in this Techno-Optimist movement. Enjoy!

    Stay Updated:

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    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

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    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not di…

  28. A New Era of VR: From the Court to the Classroom

    13 oktober 2023 · 34 min

    Afspelen
    As VR technology inches forward, completely new experiences loom on the horizon. Lees meer

    In today’s episode, we expose listeners to the very real-world use cases already present on these devices, from fitness to education.

    First up is Gym Class VR, one of the top-rated apps on the Quest. Cofounder, Paul Katsen, shows us how to dribble and dunk in the metaverse, but more importantly, discusses the social impact of VR, the technological prerequisites to get there, and the role of AI as we progress.

    Following on is a founder on a mission to revolutionize education. Anurupa Ganguly from Prisms VR, explores how virtual reality has the potential to close the gap – one where 70% of US 8th graders are not proficient in foundational math.

    Head over to our YouTube channel to see two a16z Podcast firsts: a full interview in VR, and host Steph slam dunking on an NBA court.

    Topics Covered:

    00:00 - The current state of VR

    03:38 - How do you build the #1 VR app?

    05:56 - How will VR become an everyday activity?

    07:37 - The social and the technical arc of VR

    11:47 - Untapped opportunities in VR

    13:24 - Integrating AI into VR

    17:09 - Prisms VR

    20:10 - Why it’s critical to fix America’s math problem

    21:12 - Why put VR in classrooms now?

    23:23 - The successes of VR in the classroom

    26:03 - Stats from the impact report

    27:44 - Other curriculums could benefit from VR

    31:04 - Opportunities for AI in VR

    Resources:

    Find Paul on Twitter: https://twitter.com/pavtalk

    Learn more about Gym Class: https://www.gymclassvr.com

    Find Gym Class in Meta Quest: https://www.meta.com/experiences/3661420607275144/

    Find Anurupa on LinkedIn: https://www.linkedin.com/in/anurupa-ganguly-92790379

    Learn more about Prisms VR: https://www.prismsvr.com

    Stay Updated:

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    Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

    Subscribe on your favorite podcast app: https://a16z.simplecast.com/

    Follow our host: https://twitter.com/stephsmithio

    Plea…

  29. When Will AI Hit the Enterprise? Ben Horowitz and Ali Ghodsi Discuss

    6 oktober 2023 · 26 min

    Afspelen
    Today’s episode continues our coverage from a16z’s recent AI Revolution event. You’ll hear directly from a16z cofounder Ben Horowitz and Databricks cofounder and CEO, Ali Ghodsi as they answer questions around AI and the enterprise, plus their perspectives on open source, whether benchmarks are BS, and the scramble of universities to take part in the very wave they kicked off decades ago. Lees meer

    If you’d like to access all the talks from AI Revolution in full, visit a16z.com/airevolution.

    Resources:

    Find Ali on Twitter: https://twitter.com/alighodsi

    Find Ben on Twitter: https://twitter.com/bhorowitz

    Check out Databricks: https://twitter.com/databricks

    Stay Updated:

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    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

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    Follow our host: https://twitter.com/eriktorenberg

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our coll…

  30. When AI and Genomics Collide

    3 oktober 2023 · 24 min

    Afspelen
    Today’s episode continues our coverage from a16z’s recent AI Revolution event. You’ll hear a16z Bio & Health GP Vijay Pande speak with Daphne Koller about the fascinating convergence of machine learning and genomics – two industries that have benefitted decades of investment and progress – which are now colliding head on. Lees meer

    Daphne is a prominent innovator at this intersection, as a long-time professor in computer science at Stanford and co-founder of Coursera, who has decided to step back into the arena with her company Insitro. In fact, Insitro is a blend of in silico and in virto!

    If you’d like to access all the talks from AI Revolution in full, visit a16z.com/airevolution.

    Resources:

    Find Daphne on Twitter: https://twitter.com/DaphneKoller

    Find Vijay on Twitter: https://twitter.com/vijaypande

    Find Insitro on Twitter: https://twitter.com/insitro

    Stay Updated:

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    Subscribe on your favorite podcast app: https://a16z.simplecast.com/

    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

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    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its a…

  31. AI Revolution: Disruption, Alignment, and Opportunity

    28 september 2023 · 32 min

    Afspelen
    The AI Revolution is here. In this episode, you’ll learn what the most important themes that some of the world’s most prominent AI builders – from OpenAI, Anthropic, CharacterAI, Roblox, and more – are paying attention to. You’ll hear discussion around the real-world impact of this revolution, on industries ranging from gaming to design, and the considerations around alignment along the way. Lees meer

    This footage is from an exclusive event, AI Revolution, that a16z ran in San Francisco recently. If you’d like to access all the talks in full, visit a16z.com/airevolution.

    Topics Covered:

    00:00 - AI Revolution

    02:39 - Putting technology in users’ hands

    08:21 - AI alignment and safety

    21:44 - Future opportunities

    Resources:

    Catch the all the talks at https://a16z.com/airevolution

    Stay Updated:

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    Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

    Subscribe on your favorite podcast app: https://a16z.simplecast.com/

    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

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    Follow our host: https://twitter.com/eriktorenberg

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more detail…

  32. AI Revolution: Top Lessons from OpenAI, Anthropic, CharacterAI, & More

    25 september 2023 · 38 min

    Afspelen
    The AI Revolution is here. In this episode, you’ll learn what the most important themes that some of the world’s most prominent AI builders – from OpenAI, Anthropic, CharacterAI, Roblox, and more – are paying attention to. You’ll hear about the economics of AI, broad vs specialized models, the importance of UX, and whether we can expect scaling laws to continue. Lees meer

    This footage is from an exclusive event, AI Revolution, that a16z ran in San Francisco recently. If you’d like to access all the talks in full, visit a16z.com/airevolution.

    Topics Covered

    00:00 - AI Revolution

    01:42 - The economics of AI

    06:55 - The third epoch of compute

    13:52 - Recognizing scaling laws

    17:42 - Can scaling laws continue?

    22:34 - Potential bottlenecks

    25:58 - Personalization vs generality

    29:43 - The importance of UX

    31:55 - The future of multi-modality

    Resources:

    Catch the all the talks at https://a16z.com/airevolution

    Stay Updated:

    Find a16z on Twitter: https://twitter.com/a16z

    Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

    Subscribe on your favorite podcast app: https://a16z.simplecast.com/

    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

    Stay Updated:

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    Follow our host: https://twitter.com/eriktorenberg

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investor…

  33. Engineering Rapidly Reusable Rockets

    22 september 2023 · 57 min

    Afspelen
    The space industry is evolving rapidly, with the cost of launching payloads to orbit dropping significantly. But who's investing in this sector, and how will it evolve? Lees meer

    In this episode, we delve into the transformative journey of the satellite industry with Andy Lapsa, co-founder of Stoke Space. With over a decade of experience at Blue Origin, Andy is now at the forefront of sustainable space travel, pioneering fully reusable rockets.

    Don’t forget to check out Part 1 in this mini series, where we explore the public and private players in space with John Gedmark from Astranis.

    Resources:

    Learn more about Stoke: https://www.stokespace.com

    Find Andy on Twitter: https://x.com/AndyLapsa?s=20

    Stay Updated:

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    Subscribe on your favorite podcast app: https://a16z.simplecast.com/

    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

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    Follow our host: https://twitter.com/eriktorenberg

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

    Hosted by Simplecast, an AdsWizz company. See pcm…

  34. The Evolution of the Satellite Economy

    20 september 2023 · 42 min

    Afspelen
    The cost of launching payloads to orbit has dramatically dropped, igniting a space renaissance. In 2022, a record 186 rocket launches (41 more than the previous year!) underscores this shift. Lees meer

    In Part 1 of our satellite economy mini-series, we sit down with John Gedmark, co-founder of Astranis, to reflect on today's innovations, who’s on the other side of the satellite market, the capabilities they’re looking for, competition, and their mission to provide internet access to 4 billion underserved people.

    Look out for Part 2, where we tackle the challenges of rapidly reusable rockets with Andy Lapsa from Stoke Space.

    Resources:

    Learn more about Astranis: https://www.astranis.com

    Find John on Twitter: https://x.com/Gedmark?s=20

    Stay Updated:

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    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

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    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

    Hosted by S…

  35. AI x Crypto

    13 september 2023 · 1 uur 5 min

    Afspelen
    with @alive_eth @danboneh @smc90 Lees meer

    This week's all-new episode covers the convergence of two important, very top-of-mind trends: AI (artificial intelligence) & blockchains/ crypto. These domains together have major implications for how we all live our lives everyday; so this episode is for anyone just curious about, or already building in the space.

    The conversation covers topics ranging from deep fakes, bots, and the need for proof-of-humanity in a world of AI; to big data, large language models like ChatGPT, user control, governance, privacy and security, zero knowledge and zkML; to MEV, media, art, and much more. Our expert guests (in conversation with host Sonal Chokshi) include:

    Dan Boneh, Stanford Professor (and Senior Research Advisor at a16z crypto), a cryptographer who’s been working on blockchains for over a decade and who specializes in cryptography, computer security, and machine learning -- all of which intersect in this episode;

    Ali Yahya, general partner at a16z crypto, who also previously worked at Google -- where he not only worked on a distributed system for a fleet of robots (a sort of "collective reinforcement learning") but also worked on Google Brain, where he was one of the core contributors to the machine learning library TensorFlow built at Google.

    The first half of the hallway-style conversation between Ali & Dan (who go back together as student and professor at Stanford) is all about how AI could benefit from crypto, and the second half on how crypto could benefit from AI... the thread throughout is the tension between centralization vs. decentralization. So we also discuss where the intersection of crypto and AI can bring about things that aren't possible by either one of them alone...

    pieces referenced in this episode/ related reading:

    The Next Cyber Reasoning System for Cyber Security (2023) by Mohamed Ferrag, Ammar Battah, Norbert Tihanyi, Merouane Debbah, Thierry Lestable, Lucas Cordeiro

    A New Era in Software Security: Towards …

  36. Salary Transparency: Clarity or Chaos?

    5 september 2023 · 40 min

    Afspelen
    With recent landmark legislation being passed around salary transparency, many companies are playing catch up as they interpret and implement changes. Lees meer

    In this episode, members of the a16z People Operations team, Shannon Schiltz and Brandon Cherry explore how companies can best prepare themselves to not just survive, but thrive in this new environment.

    Topics Covered:

    00:00 - Salary transparency legislation

    01:52 - The culture around pay transparency

    03:39 - What is the legislation?

    07:01 - How are companies reacting?

    11:03 - Structuring a compensation philosophy

    12:30 - Pay ranges

    15:35 - Exceptions to the pay range

    18:17 - Leveling staff

    22:30 - Ranges and roles and company growth

    28:24 - Location based pay

    30:05 - What should employees look for when applying for work?

    32:19 - Job postings

    35:05 - Reviewing compensation ranges

    35:42 - At what stage do you hire help?

    Stay Updated:

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    Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

    Subscribe on your favorite podcast app: https://a16z.simplecast.com/

    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

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    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors …

  37. A True Second Brain

    31 augustus 2023 · 48 min

    Afspelen
    How many people spend more time organizing their “second brains”, instead of leveraging the information within them? Lees meer

    With consumer AI now capable of processing simple language prompts and interfacing with unstructured data, is the landscape of information management on the brink of a transformative evolution?

    Founders of Mem, Kevin Moody and Dennis Xu, plus writer Nat Eliason, explore what’s gotten in the way of a true second brain, and how AI may finally unlock what “knowledge management” tools have promised for so long.

    Topics Covered:

    00:00 - A true second brain

    02:45 - Knowledge management

    06:01 - Thiago Forte's ‘Building a Second Brain’

    10:24 - Digital hoarding

    12:53 - The fun of organizing

    14:16 - Levels of utility

    19:09 - Can the unstructured nature of AI help?

    21:46 - What does a second brain unlock?

    25:23 - Time spent searching for information

    31:07: LLMs and technology unlocks

    34:22 - Personalization

    36:24 - Is the second brain a new PA and EA?

    38:57 - Challenges

    44:32 - Moats and differentiators

    Resources:

    Link to Mem’s website: https://mem.ai

    Find Kevin on Twitter: https://twitter.com/kevinfmoody

    Find Dennis on Twitter: https://twitter.com/DennisHXu

    FInd Nat on Twitter: https://twitter.com/nateliason

    Nat’s course on Effortless Output in Roam: https://www.effortlessoutput.com/

    Stay Updated:

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    Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

    Subscribe on your favorite podcast app: https://a16z.simplecast.com/

    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

    Stay Updated:

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  38. Wartime vs Peacetime: Ben Horowitz on Leadership

    24 augustus 2023 · 35 min

    Afspelen
    In this exclusive conversation from a16z’s Bio and Health BUILD Summit, founding partner Ben Horowitz sits down with general partner Jorge Conde. They discuss everything from the inspiration behind Ben’s book The Hard Thing About Hard Things, how the open Internet was secured, the difference between wartime and peacetime CEOs, scaling culture, and understanding how bio & healthcare differs from other forms of technology. Lees meer

    Topics Covered:

    00:00 - Introduction

    02:09 - What are the most important lessons for a CEO?

    08:45 - Surprising leaders in history

    11:41 - Wartime CEO vs the peacetime CEO

    14:54 - Cultures role

    20:59 - Communication and scaling

    25:39 - Culture as a moat

    27:46 - The interplay between startups and incumbents

    30:22 - Advice for founders on navigating AI

    Resources:

    Find Ben on Twitter: https://twitter.com/bhorowitz

    Find Jorge on Twitter: https://twitter.com/jorgecondebio

    Ben’s Book: https://www.amazon.com/Hard-Thing-About-Things-Building/dp/0062273205

    Stay Updated:

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    Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

    Subscribe on your favorite podcast app: https://a16z.simplecast.com/

    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

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    Follow our host: https://twitter.com/eriktorenberg

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to e…

  39. From Big Bang to James Webb: Exploring Space with Nobel Laureate John Mather

    18 augustus 2023 · 43 min

    Afspelen
    From artificial limbs to memory foam, many inventions have emerged from our quest to understand the cosmos. Lees meer

    In this episode we explore cosmic history, space's impact on technology, and the enduring human fascination with space exploration. To take us on this journey is astrophysicist John Mather, a Nobel Prize winner for his work on the COBE satellite and a key figure in the James Webb Space Telescope project.

    Prepare to be intrigued and left with a sense of wonder about the universe's influence on our world.

    Topics Covered:

    00:00 – Innovations through the pursuit of space

    03:52– John’s early life

    06:44 – Proving The Big Bang Theory

    13:30 – The mysteries of quantum mechanics

    15:10 – Leading the James Webb Telescope

    17:12 – Images from James Webb

    20:32 – Are we alone?

    24:20 – New telescopes

    25:18 – Engineering in space for earth

    29:31 – What would you like to see solved in your lifetime?

    32:24 – What came before The Big Bang?

    25:04 – Misconceptions about space

    37:17 – Can humans be a multiplanetary species?

    38:20 - Private vs public spending in space

    40:24 – What’s the future of space exploration?

    Resources:

    COBE satellite imagery: https://www.nasa.gov/topics/universe/features/cobe_20th.html

    Images from the James Webb Telescope: https://webbtelescope.org/images

    Exoplanet transmission spectrum: https://webbtelescope.org/contents/media/images/2022/032/01G72VSFW756JW5SXWV1HYMQK4

    Stay Updated:

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    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain

    Stay Updated:

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  40. Classroom 2050: Unleashing AI, XR, Gaming

    14 augustus 2023 · 40 min

    Afspelen
    With students learning in more places and different ways than we have ever seen, the pace of change in education is dizzying. Can this progress narrow learning gaps exacerbated by COVID-19 or will it fuel divides? How can we make the most of this once-in-a-generation opportunity? Lees meer

    Join our panelists from Khan Academy, PrismsVR, and Minecraft Education as we discuss the classroom of the future, and how important technologies including AI, XR, and gaming should play a role in it.

    Topics Covered:

    00:00 – The classroom of 2023

    04:30 – Data on the current classroom

    05:40– Developing the next gen of STEM talent

    08:00 – AI in the classroom

    13:10 – The role of gaming in the classroom

    16:00 – Misconceptions of technology in classroom

    17:51 – The ways teachers and students use AI

    21:15 - The future role of a teacher

    24:25 – Personalization and ownership in education

    27:11 – Getting hardware into the classroom

    29:54 - Misconceptions of teacher’s abilities and appetite for tech

    31:25 – Why implement these changes now?

    36:05 – Call to action for the classroom of 2050

    Resources:

    Find Sal Khan on Twitter: https://twitter.com/salkhanacademy

    Find Romy Drucker on Twitter: https://twitter.com/romydrucker

    Find Allison Matthews on LinkedIn: https://www.linkedin.com/in/allison-matthews-4050677/

    Find Anurupa on LinkedIn: https://www.linkedin.com/in/anurupa-ganguly-92790379/

    Learn more about Khan Academy: https://www.khanacademy.org/

    Learn more about The Walton Family Foundation: https://www.waltonfamilyfoundation.org/

    Learn more about Minecraft Education: https://education.minecraft.net/en-us

    Learn more about Prisms VR: https://www.prismsvr.com/

    Watch more panel discussions from The Aspen Ideas Festival 2023: https://www.aspenideas.org/

    Stay Updated:

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    Follow our host: https://twitter.co…

  41. The True Cost of Compute

    7 augustus 2023 · 14 min

    Afspelen
    With software becoming more important than ever, hardware is following suit. Lees meer

    As the world generates more data, unlocking the full potential of AI means a constant need for faster and more resilient hardware.

    But how much does this all really cost? In this final segment of our AI hardware series, we tackle that question head on.

    Be sure to check part 1 and 2, where we explore the emerging architectures and the momentous competition for AI hardware.

    Topics Covered:

    00:00 – The cost of compute

    02:20 – Is this sustainable?

    03:23 – The cost to train a model

    05:39 – Computation requirements

    09:05 – The relationship between compute, capital, and technology

    11:15 – GPT4 commenting on the technology with help from ElevenLabs

    Resources:

    Find Guido on LinkedIn: https://www.linkedin.com/in/appenz/

    Find Guido on Twitter: https://twitter.com/appenz

    Stay Updated:

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    Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

    Subscribe on your favorite podcast app: https://a16z.simplecast.com/

    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

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    Follow our host: https://twitter.com/eriktorenberg

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affil…

  42. Chasing Silicon: The Race for GPUs

    2 augustus 2023 · 22 min

    Afspelen
    With the world constantly generating more data, unlocking the full potential of AI means a constant need for faster and more resilient hardware. Lees meer

    In this episode – the second in our three-part series – we explore the challenges for founders trying to build AI companies. We dive into the delta between supply and demand, whether to own or rent, where moats can be found, and even where open source comes into play.

    Look out for the rest of our series, where we dive into terminology and technology that is the backbone of the AI, how much the cost of compute truly costs!

    Topics Covered:

    00:00 – Supply and demand

    02:44 – Competition for AI hardware

    04:32– Who gets access to the supply available

    06:16– How to select which hardware to use

    08:39– Cloud versus bringing infrastructure in house

    12:43– What role does open source play?

    15:47– Cheaper and decentralized compute

    19:04– Rebuilding the stack

    20:29– Upcoming episodes on cost of compute

    Resources:

    Find Guido on LinkedIn: https://www.linkedin.com/in/appenz/

    Find Guido on Twitter: https://twitter.com/appenz

    Stay Updated:

    Find a16z on Twitter: https://twitter.com/a16z

    Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

    Subscribe on your favorite podcast app: https://a16z.simplecast.com/

    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

    Stay Updated:

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    Follow our host: https://twitter.com/eriktorenberg

    Please note that the content here is for informational purpose…

  43. AI Hardware, Explained

    27 juli 2023 · 16 min

    Afspelen
    In 2011, Marc Andreessen said, “software is eating the world.” And in the last year, we’ve seen a new wave of generative AI, with some apps becoming some of the most swiftly adopted software products of all time. Lees meer

    So if software is becoming more important than ever, hardware is following suit. In this episode – the first in our three-part series – we explore the terminology and technology that is now the backbone of the AI models taking the world by storm. We’ll explore what GPUs are, how they work, the key players like Nvidia competing for chip dominance, and also… whether Moore’s Law is dead?

    Look out for the rest of our series, where we dive even deeper; covering supply and demand mechanics, including why we can’t just “print” our way out of a shortage, how founders get access to inventory, whether they should own or rent, where open source plays a role, and of course… how much all of this truly costs!

    Topics Covered:

    00:00 – AI terminology and technology

    03:44 - Chips, semiconductors, servers, and compute

    04:48 - CPUs and GPUs

    06:07 - Future architecture and performance

    07:01 - The hardware ecosystem

    09:05 - Software optimizations

    12:23 - What do we expect for the future?

    14:35 - Upcoming episodes on market and cost

    Resources:

    Find Guido on LinkedIn: https://www.linkedin.com/in/appenz/

    Find Guido on Twitter: https://twitter.com/appenz

    Stay Updated:

    Find a16z on Twitter: https://twitter.com/a16z

    Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

    Subscribe on your favorite podcast app: https://a16z.simplecast.com/

    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com…

  44. Growth vs Efficiency: Can You Have Both?

    21 juli 2023 · 46 min

    Afspelen
    Despite the ease of product building, sustainable growth has become increasingly challenging as many traditional channels no longer deliver the same results. Lees meer

    In these challenging times, we explore the remaining growth opportunities. How can we achieve a balance between efficiency, profitability, and growth? Which channels are still relevant and how can they be effectively mastered in 2023?

    Join us as we discuss these questions with three seasoned experts who have successfully navigated similar confusing times in the past: Gina Gotthilf, leading Latitud and renowned for her impressive tenure as the VP of Growth at Duolingo; Kieran Flanagan, a long-time SVP of Marketing at HubSpot; and Bryan Kim, Consumer Partner at a16z, who held various leadership roles during Snap's hypergrowth phase up to its IPO.

    Topics Covered:

    00:00 – What growth opportunities exist in 2023?

    03:00 – What still works in growth?

    05:02 – The fundamentals and framework of growth

    07:02 – Assessing growth potential and product lead growth

    09:33 – Distribution

    11:15 – Your moat and growth

    14:00 – Integrating AI for product lead growth

    16:23 –Trust as a moat

    17:23 – B2C growth - discovery and breaking through

    18:51 – Can you get ahead of the incumbents?

    22:03 – Examples of companies and products

    24:59 – How do you foster a growth culture?

    28:38 – Experimentation

    34:20 – How companies using AI in distribution

    44:43 – Growth challenge: What would you do with $10K?

    Resources:

    Check out Latitud: https://go.latitud.com/

    Check out Zapier: https://zapier.com/

    Find Bryan on Twitter: https://twitter.com/kirbyman01

    Find Kieran on Twitter :https://twitter.com/searchbrat

    Find Gina on Twitter: https://twitter.com/ginag

    Stay Updated:

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    Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

    Subscribe on your favorite podcast app: https://a16z.simplecast.com/

    Follow our host: https://twitter.com/stephsmithio

    Please note that the content …

  45. Curing the Trust Problem with Mark Cuban

    12 juli 2023 · 41 min

    Afspelen
    Today’s episode is with Mark Cuban, founder of multiple businesses, owner of the Dallas Mavericks, one of the sharks on Shark Tank, and cofounder of the Mark Cuban Cost Plus Drug Company. He is joined by Vijay Pande, founding partner of a16z Bio + Health. Lees meer

    Together, they talk market forces in healthcare, the importance of trust to patients, and Mark’s ideas to tackle the Gordian knot that is American healthcare.

    Listen to our last two episodes on Healthcare x Fintech:

    When Two Giants Intersect: Healthcare Meets Fintech

    How Fintech is Reshaping Our $4T Healthcare Industry

    Stay Updated:

    Find a16z on Twitter: https://twitter.com/a16z

    Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

    Subscribe on your favorite podcast app: https://a16z.simplecast.com/

    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

    Stay Updated:

    Find a16z on YouTube: YouTube

    Find a16z on X

    Find a16z on LinkedIn

    Listen to the a16z Show on Spotify

    Listen to the a16z Show on Apple Podcasts

    Follow our host: https://twitter.com/eriktorenberg

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

  46. Inside the 2023 Talent Tsunami: Layoffs, Remote Work & More

    6 juli 2023 · 43 min

    Afspelen
    Remote work is a big, divisive topic right now. Some think it’s the future, while others think it was an experiment gone wrong. Lees meer

    But it’s also not the only way to attract top talent. And the equation for doing so has only gotten more confusion as a myriad of trends intersect, from layoffs to emerging technologies like AI.

    So how can companies navigate this storm and truly attract the talent that matters? Listen in to find out.

    Topics Covered:

    00:00 – Introduction

    03:26 – What it takes to attract top talent in 2023

    06:36 – What employees really care about

    14:13 – Positives and negatives of benefits

    17:32 – Generational differences

    27:44 – Will the return to office work?

    34:35 – Differentiating through benefits

    38:35 – Advice to attract top talent

    44:16 – Closing thoughts

    Resources:

    A-Team study referenced:https://www.a.team/mission/college-grads-survey

    iCIMS study referenced: https://www.dropbox.com/s/2q3hepreozaurte/iCIMS-Class-of-2021-Report.pdf

    Most recent iCIMS study: https://www.icims.com/wp-content/uploads/2022/08/iCIMS-2023-Workforce-Report-FINAL.pdf

    Find AJ on Twitter: https://twitter.com/ItsAJThomas

    Find Rob on Twitter: https://twitter.com/RobFrohwein

    Find Hung on Twitter: https://twitter.com/HungLee

    Check out Keep Financial: https://keepfinancial.com/

    Check out Recruiting Brainfood: https://www.recruitingbrainfood.com/

    Stay Updated:

    Find a16z on YouTube: YouTube

    Find a16z on X

    Find a16z on LinkedIn

    Listen to the a16z Show on Spotify

    Listen to the a16z Show on Apple Podcasts

    Follow our host: https://twitter.com/eriktorenberg

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

    Hosted by Simplecas…

  47. The Road to Autonomous Vehicles: Are We There Yet?

    26 juni 2023 · 56 min

    Afspelen
    Self-driving cars have been on the horizon for quite some time. But, they might actually be here. Lees meer

    We got to ride around in one all over San Francisco with Waymo’s Chief Product Officer, Saswat Panigrahi.

    We discussed so much, including the five levels of autonomy, the infamous LIDAR vs video debate, regulation, UX, and the role of AI in fine-tuning these models. But most importantly, if autonomy is here… now what?!

    Topics Covered:

    00:00 - Introduction

    03:20 - A first look at Waymo

    05:21 - 5 levels of autonomy

    09:45 - Technology challenges

    14:32 - LiDAR vs video debate

    18:19 - How Waymo differentiates

    19:01 - Technological unlocks on the horizon

    20:39 - The role of AI in autonomous vehicles

    25:37 - How Waymo views safety

    32:05 - Collaborating with regulators

    37:26 - Learnings from the first 2m miles

    39:45 - Driving user retention

    43:47 - Waymo’s expansion strategy

    47:00 - Changing regulation

    47:41 - Societal unlocks enabled by autonomy

    52:21 - Will self-driving cars replace humans?

    52:58 - Closing thoughts

    Resources:

    Check out Waymo: https://waymo.com/

    Check out Waymo's Youtube channel: https://www.youtube.com/@Waymo

    Find Saswat on Twitter: https://twitter.com/saswat101

    Check out a16z's 8-part series on the autonomous vehicle ecosystem: https://a16z.com/2018/02/03/autonomy-ecosystem-frank-chen-summit/

    Stay Updated:

    Find a16z on Twitter: https://twitter.com/a16z

    Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

    Subscribe on your favorite podcast app: https://a16z.simplecast.com/

    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

    Stay Updated…

  48. Network Effects, Moats, & the Business of web3

    23 juni 2023 · 1 uur 18 min

    Afspelen
    with @skominers @smc90 Lees meer

    In this deep dive and tour through key business concepts, from theory to practice, we cover the topics of strategy, competitive advantage, network effects, moats, and more -- covering both both basic foundations, as well as the tricky nuances in a new world of open source, including web3. In the first half of this discussion, we cover foundational business concepts and questions -- such as the nature of competition, and how it *really* changes in web3; as well as how network effects really work -- and then, in the second half (in case you want to skip ahead), we cover mindsets and general guidance for builders…

    Our expert guest -- in conversation with editor in chief and host Sonal Chokshi -- is a16z crypto research partner Scott Duke Kominers, who is also a professor at Harvard Business School; a faculty affiliate in Harvard’s Department of Economics; and advises several companies on marketplace development, incentive design, and more; as well as advises, and is directly involved, in several NFT communities.

    Scott also teaches on these topics -- both at Harvard and also recently at our Crypto Startup School -- so be sure to subscribe to our playlist for those talks on the a16z crypto YouTube channel to get the latest updates as we release more videos from the 2023 cohort.

    Listen to web3 with a16z: https://web3-with-a16z.simplecast.com/

    related links // see also:

    Can web3 bring back competition to digital platforms? by Christian Catalini and Scott Duke Kominers

    Why build in web3 by Jad Esber and Scott Duke Kominers

    Vampire attacks: A theory (and thread) on 'blood sucking' platform competition by John William Hatfield and Scott Duke Kominers

    Why NFT creators are going cc0 by Flashrekt and Scott Duke Kominers

    Decentralized identity: Your reputation travels with you by Scott Duke Kominers and Jad Esber

    Increasing returns and the new world of business (1996) by W. Brian Arthur

    Network effects, origin Stories, and the evolution of tech…

  49. AI Will Save The World with Marc Andreessen and Martin Casado

    16 juni 2023 · 1 uur 3 min

    Afspelen
    This week, a16z’s own cofounder Marc Andreessen published a nearly 7,000-word article that aimed to dispel fears over AI's risks to our humanity – both real and imagined. Instead, Marc elaborates on how AI can "make everything we care about better." Lees meer

    In this timely one-on-one conversation with a16z General Partner Martin Casado, Marc discusses how this technology will maximize human potential, why the future of AI should be decided by the free market, and most importantly, why AI won’t destroy the world. In fact, it may save it.

    Read Marc’s full article “Why AI Will Save the World” here: https://a16z.com/2023/06/06/ai-will-save-the-world/

    Resources:

    Marc on Twitter: https://twitter.com/pmarca

    Marc’s Substack: https://pmarca.substack.com/

    gptplaysminecraft - Twitch: https://www.twitch.tv/gptplaysminecraft

    Why AI Will Save the World: https://a16z.com/2023/06/06/ai-will-save-the-world/

    Youtube discussion: https://www.youtube.com/watch?v=0wIUK0nsyUg

    Stay Updated:

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    Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

    Subscribe on your favorite podcast app: https://a16z.simplecast.com/

    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

    Stay Updated:

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    Follow our host: https://twitter.com/eriktorenberg

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or…

  50. The Hard Things About Scaling: Executive Hiring with Ben Horowitz and Ali Ghodsi

    14 juni 2023 · 40 min

    Afspelen
    The holy grail of company building is finding product-market fit. But what most people don’t tell you is that once you’ve found it, product-market fit brings its own set of challenges, particularly when it comes to scaling rapidly and hiring the right executives at the right time. Lees meer

    Drawing from their extensive experiences, a16z cofounder Ben Horowitz and Databricks cofounder and CEO Ali Ghodsi sit down to talk about the hardest things about executive hiring and firing, and what is at stake.

    They dive into the common reasons an exec fails, why sometimes micromanagement is a good idea, and the difference between someone who has written a playbook and someone who has only run one.

    If you’d like to dive even deeper, the Growth team at a16z has spent the last year compiling insights from dozens of leaders at late-stage startups to literally write the book on hiring executives to scale. You can find that book at: http://a16z.com/executive-hiring-playbook

    Topics Covered:

    00:00 - When is it time to let someone go?

    05:41 - When do you give someone a chance to grow into the role?

    07:05- Let go or level?

    09:27 - How do you have the tough conversation?

    16:39 - Exit packages

    18:40 - Setting a new leader up for success

    24:27 - The importance of the first quick win

    26:24 - The impact a new leader has on culture

    32:52 - Common ways new leaders fail

    37:35 - Closing thoughts

    Resources:

    Read the Executive Hiring: The Key to Scaling in the Growth Stages: http://a16z.com/executive-hiring-playbook

    Learn more about Databricks: https://www.databricks.com

    Find Ben on Twitter: https://twitter.com/bhorowitz

    Find Ali on Twitter: https://twitter.com/alighodsi

    Stay Updated:

    Find a16z on Twitter: https://twitter.com/a16z

    Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

    Subscribe on your favorite podcast app: https://a16z.simplecast.com/

    Follow our host: https://twitter.com/stephsmithio

    Please note that the content here is for informational purposes only; shoul…