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1.000 afleveringen, van nieuw naar oud
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Building AI for Creators | Luma & Phota Labs
30 juni 2026 · 48 min
Yoko Li speaks with Luma's Head of Applied Research Matt Tancik and Phota Labs cofounder and CTO Zach Xia about how AI is changing creativity, photography, and the tools people use to make art. Lees meer
The conversation explores the evolving relationship between artists and AI, from image generation and personalization to creative workflows, controllability, and agentic design tools.
They discuss personalization, photography, creative software, model design, evaluation, and why the future of creative tools may depend less on generating content and more on helping people express ideas they couldn't easily realize before. Along the way, they explore AI agents, interfaces, and how creators are already using these tools in unexpected ways.
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
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Beyond P(doom): Marc Andreessen - Betting on America
29 juni 2026 · 1 uur 5 min
Marc Andreessen joins CSIS's Navin Girishankar for a wide-ranging conversation on artificial intelligence, productivity growth, industrial policy, and America's technological future. Lees meer
Andreessen argues that while AI has already begun reshaping the economy, the largest impacts are still ahead. He explores how AI could dramatically expand access to expertise, improve productivity, and transform industries ranging from healthcare and education to law and software development. At the same time, he warns that many of the biggest barriers to progress are not technological but institutional, driven by regulation, policy choices, and infrastructure constraints.
The discussion also covers the global AI race, U.S.-China competition, export controls, data centers, energy, reindustrialization, defense technology, and the role of government in fostering innovation. Along the way, Andreessen shares his views on technological progress, national competitiveness, and why he believes America still has an opportunity to lead the next wave of economic growth.
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
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AI Is Crossing the Frontier of Human Knowledge | Kevin Weil
26 juni 2026 · 34 min
Kevin Weil, the previous CPO & Vice President of Science at OpenAI, joins Speedrun to discuss the future of AI, scientific discovery, and startup building. Lees meer
After helping build products at Twitter, Instagram, and Facebook, Weil is now focused on one of AI's most ambitious applications: accelerating science itself. He explains why modern AI models are beginning to solve problems that sit beyond the frontier of existing human knowledge, and how advances in reasoning, coding, and autonomous research could reshape fields ranging from mathematics to medicine.
The conversation explores scientific discovery, robotic labs, AI agents, product design, startup opportunities, and why the current wave of AI may create entirely new categories of companies. Along the way, Weil shares lessons from scaling products used by billions of people and explains what founders should understand about building in a world where AI capabilities continue to improve at an unprecedented pace.
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
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Marc Andreessen on AI, Technology, and the Future of Humanity
25 juni 2026 · 1 uur 4 min
Michael Malice sits down with Marc Andreessen to discuss artificial intelligence, technological progress, economic growth, and the future of human flourishing. Lees meer
Drawing on decades of experience spanning the birth of the commercial internet through today’s AI boom, Andreessen argues that many of the most common fears about technology are rooted in a misunderstanding of how innovation creates opportunity. He explains how modern AI systems work, why large language models differ from earlier visions of artificial intelligence, and why he believes AI will ultimately expand human capability rather than replace it.
The discussion covers AI, automation, productivity, cybersecurity, economic growth, creativity, and the recurring historical pattern of technological disruption. Along the way, Andreessen shares his views on optimism, abundance, and why he believes technological progress remains one of humanity’s most powerful tools for solving problems.
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What Happens to Design After AI?
24 juni 2026 · 49 min
Anish Acharya speaks with Microsoft VP of Design John Maeda and Impeccable founder and CEO Paul Bakaus about how AI is changing the practice of design. Lees meer
The conversation explores the relationship between design and technology, the rise of AI-powered creative tools, and whether automation raises the floor, the ceiling, or both. Maeda and Bakaus discuss software craftsmanship, taste, creative judgment, and why some aspects of design may become increasingly automated while others become more valuable.
They also examine agentic workflows, the future of user experience, the role of designers in an AI-native world, and how new tools may reshape the relationship between designers, engineers, and software itself.
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What’s Next for Consumer AI? | Josh Elman Joins a16z
23 juni 2026 · 54 min
Anish Acharya sits down with Josh Elman to discuss the future of consumer technology and Josh's decision to join a16z. Lees meer
Over the past two decades, Elman has helped shape some of the most important consumer technology products and companies, including LinkedIn, Facebook, Twitter, Robinhood, Discord, Musical.ly, TikTok, and Apple. Drawing on those experiences, he reflects on how technology has evolved from a niche industry into a central force in everyday life.
The conversation explores consumer AI, product design, distribution, social networks, creator ecosystems, and the changing relationship between technology and human behavior. They discuss why AI may unlock an entirely new generation of consumer products, how discovery and distribution are changing, and what founders can learn from previous platform shifts.
Along the way, Elman shares his views on retention, network effects, product-market fit, and the opportunities he believes remain underexplored in consumer technology.
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Jake Paul & Anti Fund: From Creator to Investor
22 juni 2026 · 1 uur 5 min
Jake Paul and Geoff Woo join the podcast to announce Anti Fund’s new $100 million growth fund and discuss the evolution of their investment strategy. Lees meer
The conversation covers the fund’s portfolio, including investments in companies such as SpaceX, OpenAI, Anthropic, Anduril, Cognition, Etched, and Modal, as well as the lessons they’ve learned backing founders and identifying emerging technologies. They discuss founder psychology, resilience, ambition, and why they believe attention, culture, and distribution are becoming increasingly important advantages in the AI era.
Along the way, Jake reflects on his path from creator to entrepreneur, athlete, and investor, while Geoff shares his views on venture capital, technology, and how AI is reshaping opportunity for founders and builders.
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
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The New Rules of Media | Marc Andreessen & Ben Horowitz
19 juni 2026 · 41 min
Recorded live at the New Media Summit, Marc Andreessen, Ben Horowitz, Erik Torenberg, and Gaby Goldberg discuss how media, communication, and influence are changing in the internet era. Lees meer
The conversation explores the shift from legacy media to creator-led platforms, why authenticity has become a competitive advantage, and how founders can build audiences by communicating directly with customers, employees, and the public. They discuss podcasts, social media, storytelling, corporate communications, and the changing relationship between companies, journalists, and audiences.
Along the way, they examine how founders can develop a public voice, why some leaders become influential communicators, and what it means to build a brand in a world where distribution is increasingly decentralized.
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The Fintech Playbook for Latin America
17 juni 2026 · 49 min
Angela Strange and Gabriel Vásquez speak with Addi founder and CEO Santiago Suárez about building one of Latin America's largest financial platforms. Lees meer
What began as a buy now, pay later product has evolved into a broader ecosystem spanning payments, commerce, logistics, and now banking. Serving millions of consumers and tens of thousands of merchants, Addi sits at the intersection of financial services and commerce in Colombia.
The conversation covers building in Latin America, lessons from scaling through multiple market cycles, the importance of technology infrastructure, and why Suárez believes financial inclusion and economic growth are deeply connected. They also discuss AI, organizational design, product strategy, and what it takes to build enduring companies outside Silicon Valley.
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Jack Altman on Product-Market Fit
16 juni 2026 · 29 min
Jack Altman joins Speedrun to discuss product-market fit, customer feedback, hiring, fundraising, and the realities of building an enduring company. Lees meer
Drawing on his experience building Lattice from startup to multi-billion-dollar company, Altman explains how founders should think about customer requests, when to pivot, and why some of the hardest decisions come from balancing conviction with market feedback. He shares lessons from the early days of Lattice, including finding product-market fit, building a sales motion, hiring the first employees, and navigating the tradeoffs that emerge as companies scale.
The conversation also covers fundraising, co-founder relationships, startup momentum, and what Altman looks for today as an investor at Alt Capital.
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AI, Design, and the Power of Open Models
15 juni 2026 · 43 min
Yoko Li and Justine Moore speak with Ideogram founder and CEO Mohammad Norouzi about image generation models, design workflows, and the evolving relationship between AI and creative work. Lees meer
The conversation covers Ideogram's decision to release an open-weight model, the challenges of generating text and layouts within images, and why controllability has become an increasingly important area of research. They discuss prompting, customization, editing, and the tradeoffs between general-purpose models and systems optimized for specific creative tasks.
Along the way, Norouzi shares his views on open-source AI, design tools, agentic workflows, and how image generation models may evolve as creators and enterprises seek greater control over their outputs.
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Samo Burja on Growth, Energy, and AI
12 juni 2026 · 28 min
Theo Jaffee speaks with Samo Burja, founder of Bismarck Analysis, about AI, industrial capacity, economic growth, and the institutions that shape civilization. Lees meer
The conversation explores how AI’s demand for compute, energy, and infrastructure could trigger a new wave of industrial expansion, benefiting sectors far beyond technology. Burja argues that AI is not just a software story but a demand shock that will ripple through energy, manufacturing, construction, and global supply chains.
They also discuss China and the United States, demographic decline, fertility, state capacity, welfare systems, and the political economy of automation. Along the way, Burja shares his views on functional institutions, economic growth, and why societies that can effectively organize people and resources may have an enduring advantage in the AI era.
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Designing the Physical World with AI
11 juni 2026 · 50 min
Erin Price-Wright speaks with Alex Modon, cofounder and CEO at Unlimited Industries, and Davide Asnaghi, CEO at Diode Computers, about how AI is moving from software into the physical world. They discuss automating construction and electronics design, using code and simulation to model real-world systems, and how incentives and manufacturing constraints shape adoption. They also examine what it takes to scale infrastructure, reduce build times, and unlock more abundant industrial capacity in the United States. Lees meer
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Tyler Cowen & Alex Tabarrok on AI, Jobs, and Economic Growth
9 juni 2026 · 59 min
Wyatt Thomson of OpenAI speaks with economists Tyler Cowen and Alex Tabarrok about AI, labor markets, and the future of economic growth. Lees meer
The conversation explores one of the most common fears surrounding AI: that increasingly capable systems will eliminate jobs. Cowen and Tabarrok argue instead that economic growth remains the key variable. Throughout history, productivity-enhancing technologies have transformed work, created new industries, and expanded living standards, even as they disrupted existing jobs and institutions.
They discuss automation, comparative advantage, inequality, education, healthcare, energy, and the kinds of work that may become more valuable in an AI-driven economy. Along the way, they examine longer-term questions about abundance, ownership, AI agents, and how societies can adapt to rapid technological change.
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
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AI Eats the World? A Reality Check with Benedict Evans
8 juni 2026 · 1 uur 1 min
Erik Torenberg speaks with tech analyst Benedict Evans about the current state of AI, what has changed over the past year, and which questions remain unanswered. Lees meer
The conversation covers coding agents, foundation models, AI infrastructure spending, software economics, and the tension between today's AI excitement and the long-term realities of technology adoption. Evans discusses why coding has emerged as AI's first breakout use case, how previous platform shifts can help frame the current moment, and why many of the most important questions about AI remain unresolved.
Along the way, they explore the future of software, enterprise adoption, consumer behavior, and whether AI models ultimately capture value themselves or become infrastructure for the next generation of applications.
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Building Search for AI Agents with Exa CEO Will Bryk
6 juni 2026 · 50 min
Sarah Wang speaks with Exa cofounder and CEO Will Bryk about building search infrastructure for the AI era. Lees meer
The conversation covers Exa’s origins, why traditional search engines were not designed for AI agents, and how search changes when the user is no longer a human but an autonomous system. They discuss retrieval, agent workflows, coding agents, data access, and why search may become a foundational layer for the emerging agent economy.
Along the way, Bryk shares his views on AI-native products, the future of information discovery, and why some of the most important problems in technology can ultimately be framed as search problems.
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AI Agents and the Fight for Customer Data
5 juni 2026 · 51 min
Martin Casado speaks with George Fraser, cofounder and CEO of Fivetran, about the future of data infrastructure in the age of AI. Lees meer
The conversation covers Fivetran’s merger with dbt, the changing role of data platforms, and why Fraser believes many companies are overestimating the threat AI poses to enterprise software. They discuss open data access, the backlash against AI agents accessing systems of record, and why businesses still need centralized data foundations even as agent-based workflows become more common.
Along the way, Fraser shares his views on data gravity, coding agents, enterprise AI adoption, and how AI is changing the way software companies build and operate products.
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Balaji and Steven Glinert on Network States, Supply Chains, and Allied Coalition Strategy
3 juni 2026 · 55 min
Theo Jaffee and Sophia Puccini speak with Balaji Srinivasan and Steven Glinert about the shifting balance of power between nations, networks, and technology. Lees meer
The conversation covers China’s industrial rise, America’s manufacturing challenges, the role of alliances in a multipolar world, and whether the internet is becoming a political force independent of traditional nation states. They discuss supply chains, technological sovereignty, decentralization, and competing visions for the future global order.
Along the way, Balaji outlines ideas from the Network State and Network School, while both guests debate how technology, economics, and political power may evolve over the coming decades.
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Steven Sinofsky on AI PCs, NVIDIA, and the Future of Computing
2 juni 2026 · 29 min
Theo Jaffee speaks with Steven Sinofsky about the next generation of personal computing and the growing role of AI-native hardware. Lees meer
The conversation covers NVIDIA’s entry into the PC market, Microsoft’s strategy for AI-powered devices, Apple’s hardware roadmap, and the long-running tension between backward compatibility and platform reinvention. Sinofsky explains why AI may fundamentally change how personal computers are designed, and why local inference could become increasingly important as AI workloads grow.
Along the way, they discuss Windows, Surface, Arm processors, Apple Silicon, and what the future of computing might look like as AI shifts from the cloud to devices.
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
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Building AI Agents for Enterprise Operations
1 juni 2026 · 46 min
Anish Acharya and Olivia Moore speak with Pablo Palafox and Luis Paarup about the challenges of deploying AI agents in operationally complex industries. Lees meer
The conversation covers the evolution of voice AI, enterprise workflows, and why logistics became an early proving ground for agent-based systems. They discuss context, coordination, and execution inside large organizations, as well as the role of forward-deployed engineering, enterprise deployment, and what it takes to move AI from experimentation into production.
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Why $1B Exits are Dead
29 mei 2026 · 34 min
David George, General Partner at a16z, and David Clark, CIO at VenCap, discuss how AI is reshaping venture capital and the technology industry itself. They examine why today’s AI companies are scaling faster than any previous generation of startups, and why the eventual outcomes may be significantly larger than most investors currently expect. Lees meer
The conversation covers frontier AI models, coding agents, open source competition, data center constraints, and who ultimately captures value in the AI ecosystem. They also discuss what these shifts mean for venture capital itself, including larger company outcomes, faster value creation, and the growing challenge of identifying durable winners in a market evolving at unprecedented speed.
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Stablecoins, AI Agents, and The Future of Global Banking
28 mei 2026 · 37 min
Angela Strange speaks with Dileep Thazhmon, founder and CEO of Jeeves, about building a global financial operating system for enterprises across Latin America using stablecoins and AI. Lees meer
The conversation covers the challenges of building localized financial infrastructure across 25 countries, from regulation and payments to underwriting and compliance. They also discuss why stablecoin adoption is accelerating in Latin America, and how AI is helping Jeeves scale billions in payment volume while automating underwriting, customer support, reconciliation, and KYB workflows.
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Marc Rowan on Private Markets, Software Repricing, and Capital Allocation
27 mei 2026 · 56 min
In 1990, Marc Rowan walked out of Drexel with his belongings in a cardboard box. Within a year, Apollo was managing $6 billion. Lees meer
David Haber speaks with Marc Rowan, Cofounder, CEO, and Chair of Apollo Global Management, about building Apollo into one of the world’s largest alternative asset managers and how private capital is reshaping the global economy.
The conversation covers the rise of private credit, and why Rowan believes private markets are becoming increasingly central to financing the real economy. They also discuss AI, data centers, robotics, and the growing intersection between venture-backed technology companies and large-scale private financing.
Along the way, they reflect on leadership, institutional culture, and why enduring organizations must adapt rather than protect the status quo.
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Robin Hanson on Prediction Markets, Gambling, and the Future of Forecasting
26 mei 2026 · 28 min
Theo Jaffee and Sophia Puccini speak with economist Robin Hanson about prediction markets, gambling, and why he believes speculative markets are one of the most powerful tools humans have for aggregating information and forecasting outcomes. Lees meer
The conversation begins with Minnesota’s recent law criminalizing prediction markets before expanding into the broader backlash surrounding platforms like Kalshi and Polymarket. Hanson explains his long-term vision for “decision markets,” where markets could help guide choices made by companies, governments, and even individuals.
Along the way, they discuss sports betting, games and human psychology, futurism, AI, and Hanson’s broader work on how societies misunderstand risk, incentives, and coordination
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Why AI Isn’t Killing SaaS Yet
25 mei 2026 · 40 min
Originally aired on MTS segment, Monetary Matters, Jack Farley and Max Wiethe speak with Ara Kharazian, Lead Economist at Ramp, about what real business spending data says about AI adoption, why the “SaaSpocalypse” narrative is overblown, and how companies are actually buying and deploying AI tools. They also discuss Anthropic overtaking OpenAI in Ramp’s AI Index, token-based pricing, AI productivity gains, and why many legacy software firms may be more resilient than people expect. Lees meer
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Hugging Face's Clem Delangue on Open Source AI and the LLM Bubble | MTS Live
22 mei 2026 · 16 min
Clem Delangue joins MTS to discuss the global open-source AI landscape, the current large language model bubble, and the future of consumer robotics. Lees meer
Originally aired on MTS, Theo Jaffee and Sofia Puccini speak with Clément Delangue, CEO at Hugging Face, about the global open-source AI race, why he believes the real bubble is in API-based large language models, and how robotics could become the next major interface for AI. They also discuss AI safety, U.S.-China competition, open-weight models, and why Hugging Face became the infrastructure layer for open AI development.
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How Superhuman Took Over Silicon Valley Email
21 mei 2026 · 56 min
Rahul Vohra is the founder and CEO of Superhuman, the premium email client for power users. He previously built the Gmail plug-in Reportive and sold it to LinkedIn. He began somewhere unexpected though, as a game designer on RuneScape. In this conversation, Rahul breaks down why most founders misunderstand product market fit, why premium can actually hurt your business, and how deliberate constraint can become your biggest advantage. Lees meer
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Marc Andreessen on AI, California, and the Future of America | Joe Rogan
20 mei 2026 · 3 uur 4 min
Marc Andreessen joins Joe Rogan for a conversation on AI, politics, technology, and the future of American society. They discuss how artificial intelligence is rapidly moving from novelty to infrastructure, and why Andreessen believes its long-term impact will be overwhelmingly positive despite growing public fear around automation and surveillance. Lees meer
The conversation covers the explosion of AI coding tools, the emergence of “AI agents,” and how these systems are already reshaping software development, medicine, and education. Andreessen argues that AI should be understood less as replacement technology and more as a universal layer of cognitive augmentation, giving individuals access to capabilities that previously required teams of experts.
They also discuss the political and cultural dynamics surrounding AI, from fears about mass unemployment and surveillance to concerns about censorship, centralized power, and China’s accelerating AI ecosystem. Along the way, the discussion expands into California politics, wealth taxes, urban decline, crime, housing, nuclear energy, and whether America can still build ambitious things at scale.
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Rebuilding The American Shipyard
19 mei 2026 · 13 min
Erin Price-Wright speaks with Michael Duffey and Dino Mavrookas about what it will take to rebuild the American defense industrial base for a new era of competition. As production capacity becomes a central constraint, they outline how the system must shift toward speed, scale, and modern manufacturing. Lees meer
The conversation covers the role of autonomy in both defense systems and industrial processes, and how new approaches to design, labor, and production can dramatically reduce cost and complexity. Mavrookas explains how building for software and autonomy enables entirely new classes of platforms, while Duffey emphasizes the need for structural changes in how the Department of Defense works with industry.
They also discuss the importance of commercial markets in supporting defense capabilities, the fragility of existing supply chains, and why aligning private capital with national priorities is essential to long-term resilience.
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The Plan to Make American Crime Obsolete
18 mei 2026 · 12 min
David Ulevitch speaks with Col. Jeffrey Glover and Rahul Sidhu about how AI, drones, and sensor networks are reshaping public safety and what it takes to bring new technology into law enforcement at scale. As departments face staffing shortages, burnout, and rising complexity, they examine how the right tools can make officers more effective, safer, and better supported. Lees meer
The conversation covers how drone-as-first-responder programs are changing the speed and safety of emergency response, from high-risk warrant service to Amber Alert pursuits. Glover describes how Arizona DPS is building a full technology ecosystem around its officers, including body-worn camera analytics for burnout detection, brain scan wellness checks, and international intelligence-sharing partnerships ahead of FIFA and the Olympics. Sidhu explains how Flock Safety's layered sensor network — license plate readers, gunshot detection, and drone dispatch — is turning reactive policing into proactive, data-driven response.
They also discuss what founders get wrong when building for law enforcement, why spending time on the beat matters more than any product spec, and how the next decade will fundamentally change the skills required to be a police officer in America.
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Vitalik Buterin on Human Agency in the AI Era
15 mei 2026 · 26 min
Sophia Dew and Binji Pande speak with Vitalik Buterin about technology, human agency, and how the internet is changing the way people think, build, and relate to the world around them. Drawing from his writings and personal reflections, Buterin discusses how his worldview has evolved over the last decade, from creating Ethereum as a teenager to thinking more deeply about the social and philosophical implications of technology today. Lees meer
The conversation explores the idea of “sanctuary technology,” systems that provide safety and coordination without removing individual freedom or agency. They also discuss the changing relationship between humans and AI, the risks of over-relying on automated systems, and why actively learning and thinking for yourself may become even more important as AI capabilities improve.
Along the way, Buterin reflects on creativity, community, identity, and the challenge of staying intentional in a world that increasingly pushes people toward autopilot.
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Ben Horowitz - "Your ONLY job is Right Product, Right Time"
14 mei 2026 · 19 min
Ben Horowitz shares lessons from building and scaling companies, drawing on his experience as a founder and CEO. He explains why a founder’s primary responsibility comes down to one thing: delivering the right product at the right time. Lees meer
The conversation covers how strategy actually develops in practice, why a company’s story is inseparable from its strategy, and how founders should think about hiring, fundraising, and decision-making in fast-changing environments. Horowitz also discusses how AI is reshaping teams, the increasing importance of creativity and relationships, and why roles may evolve toward more generalist “builders.”
He also reflects on navigating uncertainty, the reality of pivots, and why defensibility still comes down to solving hard problems and building meaningful relationships with customers.
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Energy, Minerals, and the Physical Stack Behind AI
13 mei 2026 · 25 min
Erin Price-Wright speaks with Turner Caldwell and Drew Baglino about what it will take to close America's critical minerals gap and modernize the power infrastructure that underpins the AI economy. With the US more than 50 years behind China in critical mineral supply and grid infrastructure built on systems designed a century ago, they examine where the real bottlenecks are and how to move faster. Lees meer
The conversation covers how automation, reinforcement learning, and vertically integrated operations can compress the timelines for mining and refining, and why co-locating supply chains matters more than labor costs in the race to reshore manufacturing. Baglino explains how solid state transformers can replace aging mechanical grid equipment with silicon and software, while Caldwell outlines how Mariana Minerals is applying autonomous systems to remove the know-how bottleneck from critical mineral processing.
They also discuss the lessons both founders carried from Tesla — techno-optimism, appetite for risk, and mission-driven talent — and what durable industrial policy, smarter permitting, and a federal grid investment framework would unlock for American competitiveness.
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Lloyd Blankfein on Risk, Crisis, and Leadership
12 mei 2026 · 1 uur 13 min
David Haber speaks with Lloyd Blankfein, former CEO of Goldman Sachs, about leadership, risk, and navigating moments of extreme uncertainty. Drawing on his experience leading Goldman through the financial crisis, Blankfein shares how organizations can build resilience, make decisions under pressure, and maintain culture while scaling. Lees meer
They discuss the importance of risk management as both a discipline and a mindset, the difference between being wrong and being reckless, and how great organizations balance taking risk with protecting against it. Blankfein also reflects on Goldman’s partnership culture, how it shaped decision-making and accountability, and what it takes to build enduring institutions over time.
The conversation also touches on technology, from the role it played in transforming financial markets to the implications of AI today, including its potential, risks, and the challenges of operating in systems that are increasingly complex and harder to fully understand.
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Marc Andreessen on Builder Culture in the Age of AI
11 mei 2026 · 1 uur 5 min
Erik Torenberg speaks with Marc Andreessen about the state of AI, media, and the broader cultural and economic shifts shaping the internet. They discuss how narratives around AI, from fear to hype, are influencing public perception, and why real-world usage tells a very different story. Lees meer
The conversation covers AI’s impact on jobs and productivity, the rise of “AI-native” builders, and why increased capability tends to expand work rather than eliminate it. Andreessen also examines how companies are adapting, from restructuring teams to rethinking roles around more generalist “builders.”
They also explore the changing media landscape, from the dynamics of influence and information to the breakdown of traditional authority, and what it means for trust, culture, and generational attitudes. Along the way, they touch on topics ranging from institutional power to emerging internet subcultures, offering a wide-ranging look at how technology is reshaping both systems and society.
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Ben Horowitz on the Next Technology Era
8 mei 2026 · 29 min
David Ulevitch speaks with Ben Horowitz about what it means to lead the technology industry at scale, and the responsibilities that come with it. Following the firm’s largest-ever fundraise, they discuss how venture capital, technology, and national strategy are increasingly intertwined. Lees meer
The conversation covers America’s role in the next technological revolution, from AI to advanced manufacturing, and why maintaining technological leadership is critical not just for economic growth, but for global influence. Horowitz also shares his perspective on working with government, supporting national security innovation, and building systems that give more people the opportunity to contribute.
They also discuss how venture capital is evolving, the shift toward larger firms and specialized strategies, and why optimism about technology, and its potential to improve lives, remains essential even amid growing skepticism.
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Crypto Fund 5: We Raised $2.2B. Here’s Why.
7 mei 2026 · 1 uur 2 min
Robert Hackett speaks with the general partners at a16z crypto about the launch of their fifth crypto fund and the current state of the industry. They reflect on how crypto has evolved from an ideological movement into a more pragmatic, product-focused ecosystem, shaped by real-world use cases and increasing regulatory clarity. Lees meer
The conversation covers the rise of stablecoins, onchain finance, and new market infrastructure, as well as the growing overlap between crypto and AI. The group also discusses how founders are shifting toward building products that work within existing systems, rather than attempting to replace them, and why this moment may represent a new phase of mainstream adoption.
They also look ahead to what success looks like for the next generation of crypto companies, from onboarding billions of users to enabling AI agents as economic actors, and the role crypto could play in shaping more open, decentralized systems in an increasingly consolidated technology landscape.
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details pl…
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The New Space Race: NASA, Artemis, and the Race to the Moon
6 mei 2026 · 30 min
Morgan Brennan speaks with NASA Administrator Jared Isaacman about the next phase of American space exploration and the urgency behind returning to the moon. They discuss the Artemis program, the challenges of cost, speed, and execution, and how a new competitive landscape is reshaping NASA’s priorities. Lees meer
The conversation covers the role of public-private partnerships, the rise of commercial space companies, and the need to rebuild core capabilities within NASA. Isaacman also outlines how the agency is shifting toward faster iteration, clearer demand signals for industry, and a more focused strategy to compete in what he describes as a new space race.
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
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Building Blackstone, Backing Costco, with Tony James
5 mei 2026 · 1 uur 24 min
David Haber speaks with Tony James about building enduring firms across multiple eras of finance. From joining DLJ when it was a subscale firm to helping grow Blackstone into one of the largest asset managers in the world, James reflects on the decisions, structures, and cultural principles that enabled long-term success. Lees meer
They discuss the origins of leveraged buyouts, the evolution of private markets, and how identifying structural opportunities early can create lasting competitive advantage. James also shares lessons from backing companies like Costco, where culture, customer focus, and long-term thinking drove exceptional outcomes.
The conversation covers leadership, talent development, and the challenges of scaling organizations while maintaining performance. James also reflects on succession, firm-building, and why culture, incentives, and alignment ultimately determine whether an organization compounds or stagnates.
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
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Sarah Rogers: Free Speech, AI Diplomacy, and What America Owes Its Allies
4 mei 2026 · 24 min
Katherine Boyle speaks with Sarah Rogers, Under Secretary for Public Diplomacy, about the intersection of AI, free speech, and global information systems. They discuss how major technological shifts, from the printing press to the internet to AI, have reshaped communication and power, and why this moment may be even more consequential. Lees meer
Recorded at the a16z American Dynamism Summit, the conversation explores the role of public diplomacy in the digital age, the risks of censorship and overregulation, and how governments are approaching AI as both a national security priority and a platform for global influence. Rogers also highlights the importance of maintaining “AI with a Western soul,” and why preserving open systems and freedom of expression will shape the future of innovation.
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
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Balaji and Taylor Lorenz on AI and Media
1 mei 2026 · 52 min
Theo Jaffee speaks with Balaji Srinivasan and Taylor Lorenz about how AI is reshaping media, trust, and online communication. Building on prior public disagreements between the two, the conversation revisits core tensions around media, technology, and power in a rapidly changing information environment. Lees meer
They discuss the breakdown of traditional information systems, the rise of AI-generated content, and why new models for verifying identity and truth may be necessary. The conversation lays out competing visions for the future of media, from decentralized “webs of trust” and cryptographic verification to the role of journalism, privacy, and public accountability.
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
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Workday’s Last Workday? AI and the Future of Enterprise Software
30 april 2026 · 29 min
Elena Burger speaks with Joe Schmidt, partner on the enterprise team at a16z, about the future of enterprise software in the age of AI. Using Workday as a case study, they discuss why many of today’s most important enterprise systems feel broken, how platform shifts reshape entire categories, and what an AI-native replacement might look like. Lees meer
The conversation covers the limits of legacy SaaS, why “AI revenue” may be overstated, and how agents could fundamentally change how companies manage workflows, permissions, and internal systems. They also explore why even the most defensible software businesses may now be vulnerable to replatforming.
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
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The Shift in Global Drug Development
29 april 2026 · 58 min
Theo Jaffee and Gabriel Dickinson speak with Cremieux about China’s rapid rise to the top of global clinical trial output. They discuss the regulatory reforms that accelerated China’s progress, the surge in novel drug development, and what the US would need to change to stay competitive in biomedical innovation. Lees meer
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
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John and Patrick Collison on Stripe's Growth, Agent Commerce, and the Future of Software
28 april 2026 · 20 min
This interview with Stripe cofounders John and Patrick Collison originally aired on TBPN. They discuss Stripe's 34% growth and new employee tender offer, how agent commerce and stablecoins may require high-throughput blockchains built for millions of transactions per second, and why the economics of software are shifting from mass-produced products to bespoke, on-demand systems cooked fresh at the moment of use. Lees meer
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
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Ben Horowitz on Venture Capital and AI
27 april 2026 · 1 uur 9 min
Anjney Midha, founder of AMP PBC, speaks with Ben Horowitz, cofounder of a16z, about how venture capital changed from a small, relationship-driven business into a scalable system for backing new technology companies. They discuss network effects, firm design, leadership, culture, and how AI is reshaping both the capital race and the kinds of companies that can be built now. Lees meer
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
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AI Inside the Enterprise
24 april 2026 · 1 uur
Steven Sinofsky, board partner at a16z, Aaron Levie, CEO of Box, and Martin Casado, general partner at a16z, discuss the reality of AI inside enterprises. They cover the gap between Silicon Valley and the rest of the world, why most AI initiatives fail in large organizations, and how agents, infrastructure, and workflows are evolving beyond the hype. Lees meer
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Martin Shkreli on AI, Pharma, and What Actually Matters
23 april 2026 · 49 min
Erik Torenberg speaks with Martin Shkreli, American investor and businessman, about how he sees the AI landscape, from OpenAI to Anthropic, and what actually matters beyond the hype. They also talk through the future of computing, the limits of “vibe coding,” and why biotech and pharma remain some of the toughest industries to get right. Lees meer
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
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Balaji Srinivasan: Prove Correct, Not Just Go Direct
22 april 2026 · 2 uur 2 min
Erik Torenberg and Theo Jaffee speak with Balaji Srinivasan, angel investor, entrepreneur, and author of The Network State, about how AI is transforming media, eroding trust, and reshaping how information is created and verified. They discuss why systems like hiring, journalism, and online communication are breaking under synthetic content, and what replaces them. The conversation also examines the role of cryptography, on-chain data, and new models of proof in rebuilding trust online. Lees meer
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
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Marc Andreessen: Monitoring the Situation and the Future of Media
21 april 2026 · 1 uur 7 min
Erik Torenberg and Theo Jaffee speak with Marc Andreessen, cofounder and general partner at a16z, about the launch of Monitoring the Situation (MTS), a new, always-on media network on X. They discuss the rise of the “current thing,” how narratives spread in real time, and why internet-native media is reshaping politics, culture, and attention. Lees meer
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
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Rethinking Git for the Age of Coding Agents with GitHub Cofounder Scott Chacon
20 april 2026 · 47 min
Matt Bornstein speaks with Scott Chacon, cofounder of GitHub and CEO of GitButler, about why Git's user interface has barely changed since 2005, how GitButler is rethinking version control for both humans and AI agents, and what the "next GitHub" might actually look like. They cover parallel branches, agent-optimized CLI design, the future of code review, and why the best engineers of the future will be the best writers. Lees meer
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
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