Latent Space: The AI Engineer Podcast
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284 afleveringen, van nieuw naar oud
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Railway: The Agent-Native Cloud — Jake Cooper
21 mei 2026 · 1 uur 29 min
Take the 2026 AI Engineering Survey and get >$2k in credits and AIE WF tickets! This was recorded before Railway suffered a major GCP outage on May 19, despite being a multi-AZ, multi-zone mesh ring, with HA fiber interconnects between their Metal <> G... Lees meer
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🔬 The Autonomous Drone Tech Stack & Economics of Drones — Yaroslav Azhnyuk, The Fourth Law & Guest Host Noah Smith, Noahpinion
18 mei 2026 · 1 uur 59 min
The future of war has been evolving before our eyes in Ukraine, yet the west still plans to fight the last war. In this special episode, guest host Noah Smith (@noahpinion) and Brandon Anderson sit down with Yaroslav Azhnyuk (@YaroslavAzhnyuk), a seria... Lees meer
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AI-Native Healthcare: 100M Doctor Visits, 10–20 Hours Saved, Prior Auth in Minutes — Janie Lee & Chai Asawa, Abridge
15 mei 2026 · 1 uur 5 min
Special discounts up for AIE Melbourne (LS discount) and AIE World’s Fair (group discounts up to 25% - CFPs still open for Autoresearch and Vertical AI) Cya there! Abridge did not start as an “GPT wrapper”. It was founded in 2018, years before the Camb... Lees meer
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⚡️ Senior Dev: This "Grill Me" Prompt Is Going Viral Among Top Engineers
7 mei 2026 · 22 min
Watch the full show on YouTube: https://www.youtube.com/watch?v=rlM_fAKxB3Q
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🔬 Doing Vibe Physics — Alex Lupsasca, OpenAI
5 mei 2026 · 1 uur 32 min
Some people are going crazy over GPT 5.5. Some people. This is the story of the Jagged Frontier. People who use AI to write emails or even code implementation work find the lift moderate whereas people pushing the limits of the model are figuring out t... Lees meer
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⚡️ Competing with ChatGPT and Sierra, building a $10M ARR company — Yasser Elsaid, Founder, Chatbase
2 mei 2026 · 1 uur
Watch the full show on YouTube: https://www.youtube.com/watch?v=CSYWbbP_OkY
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Physical AI that Moves the World — Qasar Younis & Peter Ludwig, Applied Intuition
28 april 2026 · 1 uur 12 min
From building Applied Intuition from YC-era autonomy tooling into a $15B physical AI company, Qasar Younis and Peter Ludwig have spent the last decade living through the full arc of autonomy: from simulation and data infrastructure for robotaxi compani... Lees meer
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AIE Europe Debrief + Agent Labs Thesis: Unsupervised Learning x Latent Space Crossover Special (2026)
23 april 2026 · 55 min
Today, we check in a year after the first Unsupervised Learning x Latent Space Crossover special to discuss everything that has changed (there is a lot) in the world of AI. This episode was recorded just after AIE Europe, but before the Cursor-xAI deal... Lees meer
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Shopify’s AI Phase Transition: 2026 Usage Explosion, Unlimited Opus-4.6 Token Budget, Tangle, Tangent, SimGym — with Mikhail Parakhin, Shopify CTO
22 april 2026 · 1 uur 12 min
Early bird discounts for the San Francisco World’s Fair, the biggest AIE gathering of the year, end today - prices will go up by ~$500 tonight so do please lock in ASAP! From near-universal AI tool adoption inside Shopify to internal systems for ML exp... Lees meer
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🔬 Training Transformers to solve 95% failure rate of Cancer Trials — Ron Alfa & Daniel Bear, Noetik
20 april 2026 · 1 uur 25 min
Today, we explain this piece of “clickbait” from our guest! TL;DR: 95% of cancer treatments fail to pass clinical trials, but it may be a matching problem — if we better understood what patients have which tumors which will respond to which treatments,... Lees meer
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⚡️ How to turn Documents into Knowledge: Graphs in Modern AI — Emil Eifrem, CEO Neo4J
19 april 2026 · 49 min
Watch the full show on YouTube: https://www.youtube.com/watch?v=yyuVR-ML9X8
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Notion’s Token Town: 5 Rebuilds, 100+ Tools, MCP vs CLIs and the Software Factory Future — Simon Last & Sarah Sachs of Notion
15 april 2026 · 1 uur 17 min
For all those who missed out on London, see you in Miami next week! Notion, the knowledge work decacorn, has been building AI tooling since before ChatGPT, with many hits from Q&A in 2023 and unified AI in 2024 and Meeting Notes in 2025. At the end of ... Lees meer
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⚡️ The best engineers don't write the most code. They delete the most code. — Stay Sassy
13 april 2026 · 58 min
Watch the full show on YouTube: https://www.youtube.com/watch?v=5KnCKadxSPY
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Extreme Harness Engineering for Token Billionaires: 1M LOC, 1B toks/day, 0% human code, 0% human review — Ryan Lopopolo, OpenAI Frontier & Symphony
7 april 2026 · 1 uur 13 min
We’re proud to release this ahead of Ryan’s keynote at AIE Europe. Hit the bell, get notified when it is live! Attendees: come prepped for Ryan’s AMA with Vibhu after. Move over, context engineering. Now it’s time for Harness engineering and the age of... Lees meer
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Marc Andreessen introspects on The Death of the Browser, Pi + OpenClaw, and Why "This Time Is Different"
3 april 2026 · 1 uur 16 min
Fresh off raising a monster $15B, Marc Andreessen has lived through multiple computing platform shifts firsthand, from Mosaic and Netscape to cofounding A16z. In this episode, Marc joins swyx and Alessio in a16z’s legendary Sand Hill Road office to arg... Lees meer
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Moonlake: Causal World Models should be Multimodal, Interactive, and Efficient — with Chris Manning and Fan-yun Sun
2 april 2026 · 1 uur 7 min
We’ve been on a bit of a mini World Models series over the last quarter: from introducing the topic with Yi Tay, to exploring Marble with World Labs’ Fei-Fei Li and Justin Johnson, to previewing World Models learned from massive gaming datasets with Ge... Lees meer
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Mistral: Voxtral TTS, Forge, Leanstral, & what's next for Mistral 4 — w/ Pavan Kumar Reddy & Guillaume Lample
30 maart 2026 · 49 min
Mistral has been on an absolute tear - with frequent successful model launches it is easy to forget that they raised the largest European AI round in history last year. We were long overdue for a Mistral episode, and we were very fortunate to work with... Lees meer
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🔬 Why There Is No "AlphaFold for Materials" — AI for Materials Discovery with Heather Kulik
24 maart 2026 · 35 min
Materials science is the unsung hero of the science world. Behind every physical product you interact was decades of research into getting the properties of materials just right. Your gym clothes contain synthetic fibers developed over decades. The gla... Lees meer
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Dreamer: the Personal Agent OS — David Singleton
20 maart 2026 · 1 uur 4 min
Mar 23 update for Latent Spacenauts: this episode was recorded before the Dreamer team announced they were joining Meta Superintelligence Labs, and it turned out to be the last interview they did before the news became public. Consider this a snapshot ... Lees meer
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Why Anthropic Thinks AI Should Have Its Own Computer — Felix Rieseberg of Claude Cowork & Claude Code Desktop
17 maart 2026 · 1 uur 27 min
Claude Cowork came out of an accident. Felix and the Anthropic team noticed something interesting with Claude Code: many users were using it primarily for all kinds of messy knowledge work instead of coding. Even technical builders would use it for lot... Lees meer
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⚡️ Monty: the ultrafast Python interpreter by Agents for Agents — Samuel Colvin, Pydantic
14 maart 2026 · 34 min
Watch the full show on YouTube: https://www.youtube.com/watch?v=nxnQl4AcqFg
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Retrieval After RAG: Hybrid Search, Agents, and Database Design — Simon Hørup Eskildsen of Turbopuffer
12 maart 2026 · 1 uur 1 min
Turbopuffer came out of a reading app. In 2022, Simon was helping his friends at Readwise scale their infra for a highly requested feature: article recommendations and semantic search. Readwise was paying ~$5k/month for their relational database and ve... Lees meer
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NVIDIA's AI Engineers: Agent Inference at Planetary Scale and "Speed of Light" — Nader Khalil (Brev), Kyle Kranen (Dynamo)
10 maart 2026 · 1 uur 24 min
Join Kyle, Nader, Vibhu, and swyx live at NVIDIA GTC next week! Now that AIE Europe tix are ~sold out, our attention turns to Miami and World’s Fair! The definitive AI Accelerator chip company has more than 10xed this AI Summer: And is now a $4.4 trill... Lees meer
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⚡️ OpenClaw's Memory Sucks and the fix is simple — Dhravya Shah, Supermemory
9 maart 2026 · 27 min
Watch the full show on YouTube: https://www.youtube.com/watch?v=Io0mAsHkiRY
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Cursor's Third Era: Cloud Agents
6 maart 2026 · 1 uur 7 min
All speakers are announced at AIE EU, schedule coming soon. Join us there or in Miami with the renowned organizers of React Miami! Singapore CFP also open! We’ve called this out a few times over in AINews, but the overwhelming consensus in the Valley i... Lees meer
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Every Agent Needs a Box — Aaron Levie, Box
5 maart 2026 · 1 uur 17 min
The reception to our recent post on Code Reviews has been strong. Catch up! Amid a maelstrom of discussion on whether or not AI is killing SaaS, one of the top publicly listed SaaS companies in the world has just reported record revenues, clearing well... Lees meer
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⚡️ Polsia: Solo Founder Tiny Team from 0 to 1m ARR in 1 month & the future of Self-Running Companies
1 maart 2026 · 42 min
Watch the full show on YouTube: https://www.youtube.com/watch?v=Yw-m0PI2Atk
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METR’s Joel Becker on exponential Time Horizon Evals, Threat Models, and the Limits of AI Productivity
27 februari 2026 · 56 min
This is a free preview of a paid episode. To hear more, visit www.latent.space AIE Europe CFP and AIE World’s Fair paper submissions for CAIS peer review are due TODAY - do not delay! Last call ever. We’re excited to welcome METR for their first LS Pod... Lees meer
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[LIVE] Anthropic Distillation & How Models Cheat (SWE-Bench Dead) | Nathan Lambert & Sebastian Raschka
26 februari 2026 · 52 min
Swyx joined SAIL! Thank you SAIL Media, Prof. Tom Yeh, 8Lee, Hamid Bagheri, c9n, and many others for tuning into SAIL Live #6 with Nathan Lambert and Sebastian Raschka, PhD. Sharing here for the LS paid subscribers. We covered: This is a public episode... Lees meer
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🔬 Searching the Space of All Possible Materials — Prof. Max Welling, CuspAI
25 februari 2026 · 34 min
Editor’s note: CuspAI raised a $100m Series A in September and is rumored to have reached a unicorn valuation. They have all-star advisors from Geoff Hinton to Yann Lecun and team of deep domain experts to tackle this next frontier in AI applications. ... Lees meer
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Claude Code for Finance + The Global Memory Shortage: Doug O'Laughlin, SemiAnalysis
24 februari 2026 · 2 uur 4 min
This is a free preview of a paid episode. To hear more, visit www.latent.space First speakers for AIE Europe and AIEi Miami have been announced. If you’re in Asia/Aus, come by Singapore and Melbourne. AI Engineering is going global! One year ago today,... Lees meer
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⚡️ The End of SWE-Bench Verified — Mia Glaese & Olivia Watkins, OpenAI Frontier Evals & Human Data
23 februari 2026 · 26 min
Olivia Watkins (Frontier Evals team) and Mia Glaese (VP of Research at OpenAI, leading the Codex, human data, and alignment teams) discuss a new blog post (https://openai.com/index/why-we-no-longer-evaluate-swe-bench-verified/) arguing that SWE-Bench V... Lees meer
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Bitter Lessons in Venture vs Growth: Anthropic vs OpenAI, Noam Shazeer, World Labs, Thinking Machines, Cursor, ASIC Economics — Martin Casado & Sarah Wang of a16z
19 februari 2026 · 55 min
Tickets for AIEi Miami and AIE Europe are live, with first wave speakers announced! From pioneering software-defined networking to backing many of the most aggressive AI model companies of this cycle, Martin Casado and Sarah Wang sit at the center of t... Lees meer
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Owning the AI Pareto Frontier — Jeff Dean
12 februari 2026 · 1 uur 24 min
From rewriting Google’s search stack in the early 2000s to reviving sparse trillion-parameter models and co-designing TPUs with frontier ML research, Jeff Dean has quietly shaped nearly every layer of the modern AI stack. As Chief AI Scientist at Googl... Lees meer
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🔬 Beyond AlphaFold: How Boltz is Open-Sourcing the Future of Drug Discovery
12 februari 2026 · 1 uur 21 min
This podcast features Gabriele Corso and Jeremy Wohlwend, co-founders of Boltz and authors of the Boltz Manifesto, discussing the rapid evolution of structural biology models from AlphaFold to their own open-source suite, Boltz-1 and Boltz-2. The centr... Lees meer
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⚡️ Reverse Engineering OpenAI's Training Data — Pratyush Maini, Datology
10 februari 2026 · 27 min
Watch the full show on YouTube: https://www.youtube.com/watch?v=CSgjaC6y6Mk
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The First Mechanistic Interpretability Frontier Lab — Myra Deng & Mark Bissell of Goodfire AI
6 februari 2026 · 1 uur 8 min
From Palantir and Two Sigma to building Goodfire into the poster-child for actionable mechanistic interpretability, Mark Bissell (Member of Technical Staff) and Myra Deng (Head of Product) are trying to turn “peeking inside the model” into a repeatable... Lees meer
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⚡️ Context Graphs: according to the authors — Jaya Gupta, Ashu Garg, Foundation Capital
4 februari 2026 · 34 min
Watch the full show on YouTube: https://www.youtube.com/watch?v=zP8P7hJXwE0
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🔬 Automating Science: World Models, Scientific Taste, Agent Loops — Andrew White
28 januari 2026 · 1 uur 14 min
Editor’s note: Welcome to our new AI for Science pod, with your new hosts RJ and Brandon! See the writeup on Latent.Space (https://Latent.Space) for more details on why we’re launching 2 new pods this year. RJ Honicky is a co-founder and CTO at MiraOmi... Lees meer
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⚡️ Prism: OpenAI's LaTeX "Cursor for Scientists" — Kevin Weil & Victor Powell, OpenAI for Science
27 januari 2026 · 36 min
Watch the full show on YouTube: https://www.youtube.com/watch?v=W2cBTVr8nxU
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Captaining IMO Gold, Deep Think, On-Policy RL, Feeling the AGI in Singapore — Yi Tay
23 januari 2026 · 1 uur 32 min
From shipping Gemini Deep Think and IMO Gold to launching the Reasoning and AGI team in Singapore, Yi Tay has spent the last 18 months living through the full arc of Google DeepMind’s pivot from architecture research to RL-driven reasoning—watching his... Lees meer
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Brex’s AI Hail Mary — With CTO James Reggio
17 januari 2026 · 1 uur 13 min
From building internal AI labs to becoming CTO of Brex, James Reggio has helped lead one of the most disciplined AI transformations inside a real financial institution where compliance, auditability, and customer trust actually matter. We sat down with... Lees meer
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Artificial Analysis: Independent LLM Evals as a Service — with George Cameron and Micah-Hill Smith
8 januari 2026 · 1 uur 18 min
Happy New Year! You may have noticed that in 2025 we had moved toward YouTube as our primary podcasting platform. As we’ll explain in the next State of Latent Space post, we’ll be doubling down on Substack again and improving the experience for the ove... Lees meer
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[State of Evals] LMArena's $1.7B Vision — Anastasios Angelopoulos, LMArena
6 januari 2026 · 24 min
We are reupping this episode after LMArena announced their fresh Series A (https://www.theinformation.com/articles/ai-evaluation-startup-lmarena-valued-1-7-billion-new-funding-round?rc=luxwz4), raising $150m at a $1.7B valuation, with $30M annualized c... Lees meer
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[NeurIPS Best Paper] 1000 Layer Networks for Self-Supervised RL — Kevin Wang et al, Princeton
2 januari 2026 · 28 min
From undergraduate research seminars at Princeton to winning Best Paper award at NeurIPS 2025, Kevin Wang, Ishaan Javali, Michał Bortkiewicz, Tomasz Trzcinski, Benjamin Eysenbach defied conventional wisdom by scaling reinforcement learning networks to ... Lees meer
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[State of Code Evals] After SWE-bench, Code Clash & SOTA Coding Benchmarks recap — John Yang
31 december 2025 · 18 min
From creating SWE-bench in a Princeton basement to shipping CodeClash, SWE-bench Multimodal, and SWE-bench Multilingual, John Yang has spent the last year and a half watching his benchmark become the de facto standard for evaluating AI coding agents—tr... Lees meer
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[State of Post-Training] From GPT-4.1 to 5.1: RLVR, Agent & Token Efficiency — Josh McGrath, OpenAI
31 december 2025 · 28 min
From pre-training data curation to shipping GPT-4o, o1, o3, and now GPT-5 thinking and the shopping model, Josh McGrath has lived through the full arc of OpenAI’s post-training evolution—from the PPO vs DPO debates of 2023 to today’s RLVR era, where th... Lees meer
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[State of RL/Reasoning] IMO/IOI Gold, OpenAI o3/GPT-5, and Cursor Composer — Ashvin Nair, Cursor
30 december 2025 · 45 min
From Berkeley robotics and OpenAI’s 2017 Dota-era internship to shipping RL breakthroughs on GPT-4o, o1, and o3, and now leading model development at Cursor, Ashvin Nair has done it all. We caught up with Ashvin at NeurIPS 2025 to dig into the inside s... Lees meer
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[State of AI Startups] Memory/Learning, RL Envs & DBT-Fivetran — Sarah Catanzaro, Amplify
30 december 2025 · 29 min
From investing through the modern data stack era (DBT, Fivetran, and the analytics explosion) to now investing at the frontier of AI infrastructure and applications at Amplify Partners, Sarah Catanzaro has spent years at the intersection of data, compu... Lees meer
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One Year of MCP — with David Soria Parra and AAIF leads from OpenAI, Goose, Linux Foundation
27 december 2025 · 1 uur 39 min
One year ago, Anthropic launched the Model Context Protocol (MCP) —a simple, open standard to connect AI applications to the data and tools they need. Today, MCP has exploded from a local-only experiment into the de facto protocol for agentic systems, ... Lees meer