Alle afleveringen
367 afleveringen, van nieuw naar oud
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TWiM #67: Black mushrooms and RNA thermosensors
30 oktober 2013 · 1 uur 16 min
Vincent, Elio, and Michael discuss how temperature triggers Neisseria menigitidis immune evasion, and protection of mice from ionizing radiation by feeding them black mushrooms.
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TWiM #66: The shape of a container
17 oktober 2013 · 1 uur 9 min
Vincent, Elio, Michael, and Michele discuss the curious outer membrane vesicles of Neisseria meningitides, and sources of Clostridium difficile infection revealed by genome sequencing.
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TWiM #65: Leanness is transmissible
3 oktober 2013 · 51 min
Hosts: Vincent Racaniello and Michelle Swanson. Lees meer
Vincent and Michelle reveal how the human gut microbiota can modulate obesity in mice.
Links for this episode:
Gut microbiota modulate metabolism (Science)
Fighting obesity with bacteria (Science)
Letters read on TWiM 065
Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.
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TWiM #64: URI and UTI at ICAAC in Denver
18 september 2013 · 1 uur 18 min
Vincent and Michael recorded this episode at the 53rd ICAAC in Denver, where they spoke with James Gern and James Johnson about rhinoviruses and extra-intestinal pathogenic E. coli.
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TWiM #63: Superantigens, S. aureus, and the armpit microbiome
5 september 2013 · 1 uur 26 min
Vincent, Michael, and Michelle discuss how a Staphylococcus aureus superantigen is critical for pathogenesis in a rabbit model, and the relationship of body odor to the axilla microbiome.
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TWiM #62: Breaking bad and protein chain mail
21 augustus 2013 · 1 uur 20 min
Vincent and Michael discuss how infection with influenza A virus disperses Streptococcus pneumoniae biofilms leading to disease, and an amazing protein chainmail in a viral capsid
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TWiM #61: The irony of probiotics
7 augustus 2013 · 1 uur
Vincent, Elio, and Michele review how horizontal gene transfer from bacteria to an insect genome enables a tripartite nested mealybug symbiosis, and how probiotic bacteria work by competing for iron in the intestine.
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TWiM #60: Microbial electrochemistry and diversity-generating retroelements
24 juli 2013 · 1 uur 11 min
Vincent, Elio, and Michael discuss how an error-prone reverse transcriptase produces enormous diversity in a Legionella protein, and using microbes to convert waste into bioelectricity and chemicals.
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TWiM #59: Are viruses part of our immune system?
10 juli 2013 · 1 uur 25 min
Vincent and Michael discuss the finding that bacteriophage might be part of the mucosal antimicrobial defense system.
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TWiM #58: The brain microbiome?
20 juni 2013 · 1 uur 22 min
Vincent, Elio and Michael review how underground mycelial networks carry signals that warn neighboring plants of aphid attack, and the presence of bacteria in the human brain.
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TWiM #57: Updating the human gut microbiome to degrade seaweed
5 juni 2013 · 59 min
Vincent, Elio and Michael discuss fungi that use pheromones to trap nematodes, and how genes obtained from marine bacteria help gut bacteria degrade algal carbohydrates.
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TWiM #56: Live at ASM in Denver
24 mei 2013 · 1 uur 42 min
Vincent, Elio and Michael recorded this episode before an audience at the 2013 General Meeting of the American Society for Microbiology in Denver, Colorado, where they spoke with Andrew, Ferric, Suzanne, and Michelle about their research on a phage system for evading innate immunity, retractions of research papers, bacterial infections of the eye, and cytoplasmic defenses against intracellular bacteria. Lees meer
This episode was filmed live at ASM GM 2013 in Denver, CO. Visit www.microbeworld.org/asmlive to watch the full video archive of this episode as well as all the videos recorded during GM.
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TWiM #55: In the copper room
24 april 2013 · 1 uur 25 min
Vincent, Elio and Michael discuss the finding that copper surfaces reduce microbial burden and hospital-acquired infections in the intensive care unit.
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TWiM #54: Dueling injectors and the microgenderome
10 april 2013 · 1 uur 13 min
Vincent, Elio, and Michael review how sex-dependent differences in the mouse microbiome regulate type I diabetes, and counterattack among bacteria.
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TWiM #53: Live in Manchester
29 maart 2013 · 1 uur 1 min
Vincent, Laura, David, Kalin and Paul get together at the Society for General Microbiology meeting in Manchester, England to talk about next-generation approaches to antimicrobial therapy.
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TWiM #52: Clinical microbiology with Ellen Jo Baron
11 maart 2013 · 1 uur
Vincent and Michael meet up with Ellen Jo Baron to talk about working in a clinical microbiology laboratory.
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TWiM #51: Cave science with Hazel Barton
27 februari 2013 · 1 uur 19 min
Vincent, Michael, and Elio meet up with Hazel Barton to talk about cave microbiology.
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TWiM #50: These things aren't even bacteria!
30 januari 2013 · 1 uur 4 min
Vincent, Michael, and Stanley review the scientific career of Carl Woese.
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TWiM #49: Grape-like Clusters
16 januari 2013 · 1 uur 14 min
Vincent, Michael, and Elio discuss the HIV co-receptor CCR5 as a receptor for S. aureus leukotoxin ED, and the vineyard yeast microbiome.
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TWiM #48: It's all about direction
3 januari 2013 · 1 uur 16 min
Vincent, Michael, and Jo discuss how subtle gender bias of science faculty favors male students, and the relationship of invasive infection and antibody orientation at bacterial surfaces.
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TWiM #47: Resistance on the surface
19 december 2012 · 1 uur 11 min
Horizontal transfer of antibiotic resistance genes on metal surfaces, and using bacteriophage to reverse antibiotic resistance.
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TWiM #46: Spore!
5 december 2012 · 1 uur 10 min
Vincent, Michael, and Elio meet up with Jonathan Dworkin to discuss how bacteria form spores and how they return to vegetative growth.
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TWiM #45: Secreted nucleic acids RIG a STING
21 november 2012 · 1 uur 12 min
Vincent, Michael, Elio review innate immune sensing of Listeria secreted bacterial nucleic acids, and how Wolbachia enhances egg production in Drosophila.
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TWiM #44: Phage interruptus
24 oktober 2012 · 1 uur 6 min
Vincent, Michael, Elio discuss the role of prophage excision in exit of Listeria from the phagosome, and analysis of bacterial communities in saliva.
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TWiM #43: Bacterial caveolae and zapping acne with phages
10 oktober 2012 · 1 uur 20 min
Vincent, Michael, Elio review formation of caveolae in a bacterium, and the limited genetic diversity and broad killing activity of P. acnes bacteriophages.
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TWiM #42: Staphylococcus, a three-star pathogen
26 september 2012 · 1 uur 12 min
Vincent, Michael, Elio, and Joe review highlights of the 15th International Symposium on Staphylococci and Staphylococcal Infections (ISSSI) in Lyon, France.
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TWiM #41: ICAAC live in San Francisco
13 september 2012 · 1 uur 43 min
Vincent and Michael travel to San Francisco for the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), where they meet with Bill, John, and Victor to discuss tuberculosis, monitoring infectious disease outbreaks with online data, and outside-the-box approaches to antibacterial therapy. Lees meer
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TWiM #40: A mecca for microbiology
29 augustus 2012 · 1 uur 2 min
**MicrobeWorld app users, click the "e" symbol in the bottom right corner of this description to watch a bonus video version of this episode!** Lees meer
Vincent and Stanley meet with Waclaw Szybalski and John Kirby at Cold Spring Harbor Laboratory on the occasion of its designation as a Milestones in Microbiology site. They reminisce about how the well known laboratory has advanced the science and teaching of microbiology, and discuss John’s work on the soil dwelling, predatory myxobacteria.
If you don't have the app, please visit www.microbeworld.org/app to get more information about downloading the app for your iOS or Android device.
This video is also available for free at www.microbeworld.org in the TWiM section, epsiode #40.
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TWiM #39: What Darwin never knew
15 augustus 2012 · 1 uur 16 min
Vincent, Michael, and Elio reviews chapters from Microbes and Evolution, a collection of short, personal essays by microbiologists.
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TWiM #38: The sound of whooping cough
2 augustus 2012 · 1 uur 11 min
Vincent, Jo, Michael, and Elio review an outbreak of pertussis in Washington, and how culturing can reveal rare members of the soil biosphere.
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TWiM #37: Microbial Jekyll and Hyde
18 juli 2012 · 1 uur 18 min
Vincent, Jo, Michael, and Elio discuss two examples of dynamic microbial symbioses that switch between mutualistic and pathogenic states.
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TWiM #36: Domesticating a pathogen
4 juli 2012 · 1 uur 20 min
Vincent, Michael, and Elio explore the origin of Mycoplasma pathogens of ruminants, and share their thoughts on the recent ASM General Meeting.
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TWiM #35: Ohne hauch
21 juni 2012 · 1 uur 10 min
Vincent, Michael, and Elio review necrotizing fasciitis, and a link between surface remodeling in gram-positive and gram-negative bacteria.
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TWiM #34: Doing the DISCO with Emiliania
4 juni 2012 · 1 uur 9 min
Hosts: Vincent Racaniello, Michael Schmidt, and Elio Schaechter Lees meer
Vincent, Michael, and Elio discuss changing populations of Emiliania huxleyi and their viruses in the North and Black Seas.
Right click to download TWiM #34 (50 MB .mp3, 69 minutes).
Links for this episode:
The protist wonderland (Microbe)
Emiliania huxleyi home page
DISCO in the North Sea (FEMS Microbiol Ecol)
7000 years of Emiliania huxleyi in the Black Sea (Science)
Cheshire cat escape by Emiliania huxleyi (PNAS)
Letters read on TWiM 34
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TWiM #33: Tuning the immune organ
16 mei 2012 · 1 uur 8 min
Vincent, Michael, and Ivo review the requirement for segmented, filamentous bacteria for the induction of a specific type of helper T cell in the gut. Lees meer
Links for this episode:
Induction of Th17 cells by segmented filamentous bacteria (Cell)
Segmented filamentous bacteria take the stage (Nature)
Genome of segmented filamentous bacteria reveals auxotrophy (Cell)
Segmented filamentous bacteria and diabetes protection (PNAS)
Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv ,
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TWiM #32: Not the shadow biosphere
2 mei 2012 · 1 uur 7 min
Rosie Redfield talks about her evidence that a bacterium cannot grow on arsenic instead of phosphorus.
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TWiM 31: Screen door on a submarine
18 april 2012 · 1 uur 15 min
Hosts: Vincent Racaniello, Jo Handelsman, and Michael Schmidt Lees meer
Vincent, Jo, and Michael discuss an archetypal protein transport system in bacterial outer membranes, and evidence that gut microbial enterotypes might not fall into defined groups.
Links for this episode:
Discovery of a TAM, a new bacterial protein transport system (Nat Struct Mol Biol)
Commentary on TAM discovery
Enterotypes of the human gut microbiome (Nature)
Gut enterotypes might be less clear-cut (Ed Yong)
Letters read on TWiM #31
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TWiM #30: Unraveling melioidosis and insulin resistance
4 april 2012 · 1 uur 10 min
On episode #30 of the podcast, Vincent, Elio, and Michael review how a toxin from Burkholderia pseudomallei inhibits protein synthesis, and the role of the gut microbiome in modulating insulin resistance in mice lacking an innate immune sensor.
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TWiM #29: Death and an iron-loaded spike
21 maart 2012 · 1 uur 3 min
On episode #29 of the podcast, Vincent and Stanley review how a phage pierces the cell membrane with an iron-loaded spike, and two programmed cell death systems in E. coli.
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TWiM #28: Not unorganized bags of enzymes
7 maart 2012 · 1 uur 17 min
Vincent, Michael, and Elio review how competition within a host drives virulence of Streptococcus pneumoniae, and the expanding universe of the bacterial cytoskeleton.
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TWiM #27: An inflamed gut is good for Salmonella
22 februari 2012 · 1 uur 15 min
Vincent, Elio, and Michael review how inflammation allows Salmonella to compete with fermenting gut microbes, and a riboswitch in bacterial and Archeal species that is triggered by fluoride.
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TWiM #26: Suum cuique
8 februari 2012 · 1 uur 15 min
Vincent, Elio, and Michael discuss the finding of Sutterella species in the gut of autistic children, and methods for cultivating oral bacteria.
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TWiM #25: Magnetotactic bacteria and totally drug resistant TB
25 januari 2012 · 1 uur 17 min
On episode #25 of the podcast, Vincent, Elio, and Michael review bacteria that use the earth’s magnetic field for navigation, and identification of totally drug resistant Mycobacterium tuberculosis.
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TWiM #24: This year in microbiology
11 januari 2012 · 1 uur 19 min
Vincent, Michael, and Cliff review ten compelling microbiology stories from 2011.
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TWiM #23: Fighting antibiotics with toxic gas and starvation
28 december 2011 · 1 uur 16 min
Vincent, Jo, Elio, and Michael explain how a swarming bacterium helps disperse a non-motile fungus, and bacterial antibiotic tolerance mediated by hydrogen sulfide and starvation responses.
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TWiM #22: Microbiology 911
14 december 2011 · 1 uur 38 min
Vincent and Michael speak with Alfred Sacchetti, MD, Chief of Emergency Services at Our Lady of Lourdes Medical Center, about microbial infections encountered in the emergency room.
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TWiM #21: Symbiotic margheritas
30 november 2011 · 1 uur 8 min
Vincent and Elio discuss ancient symbiosis between Alphaproteobacteria and catenulid flatworms, and a toxin from Helicobacter pylori that engages the mitochondrial fission machinery to induce host cell death.
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TWiM #20: Facebook for bacteria
16 november 2011 · 1 uur 8 min
On episode #20 of the podcast This Week in Microbiology, Vincent, Michael, and Elio follow up on the outbreaks of E. coli in Germany and cholera in Haiti, then discuss genes that confer self-identity to Proteus mirabilis.
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TWiM #19: Your microbiome is what you eat
2 november 2011 · 59 min
Vincent, Michael, Elio, and Jo discuss the genome sequence of Y. pestis from victims of the Black Death, and the effect of diet on gut microbial enterotypes.
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TWiM #18: Escherichia coli K-12, an emerging pathogen?
19 oktober 2011 · 1 uur 14 min
Vincent, Michael, Elio, and Stanley explain how to make the human intestinal commensal and benign laboratory bacterium Escherichia coli K-12 into an invasive organism, and the unearthing of century-old spores in New York City.