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Shrinking the Gap Between Sci-Fi and Sci-Fact (Josh Wolfe, Co-Founder of Lux Capital)
15 april 2025 · 1 uur 27 min
Friends, Lees meer
What if you could record the smell of your grandmother’s kitchen or detect diseases with a breath? Josh Wolfe, co-founder of Lux Capital, is funding the breakthroughs that are turning these concepts into reality.
In this episode of The Generalist, Josh discusses how Lux Capital is backing companies like eGenesis, which is transplanting gene-edited pig organs into humans; Osmo, pioneering digital olfaction technology; and Variant Bio, which is studying genetic outliers in indigenous populations whose DNA could lead to life-saving medical advancements.
Science fiction doesn’t just predict the future, it creates it. Josh’s investment approach is deeply influenced by speculative fiction, which has inspired many of the groundbreaking companies in his portfolio. This visionary thinking has driven Lux to fund startups working on technologies once considered impossible.
Josh also shares how stories shape his worldview, how he stays on top of macro trends, where America is trailing China in the AI race, and how we can catch up.
In our conversation, we explore:
* The revolutionary development of genetically modified pig organs being transplanted into humans and what this means for the future of organ transplantation.
* The recent achievement of "teleporting smell" across space and why computers that can replicate scents will open up entirely new industries.
* Why Lux is investing in the search for real-life "X-Men" — genetic outliers in isolated populations whose DNA could lead to life-saving medical advancements.
* How Josh evaluates macro trends to make smarter micro investment decisions and why ignoring the big picture is a mistake.
* The three tech sectors that Josh believes will define the geopolitical balance in the decades ahead.
* How Josh stays current on macroeconomic trends.
* Much more
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Introducing The Generalist Podcast
7 april 2025 · 2 min
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