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364 afleveringen, van nieuw naar oud
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Ep. 291: “Functional Precision Medicine” Featuring Dr. Scott Younger
1 april 2025 · 1 uur 25 min
Dr. Scott Younger is the Director of Disease Gene Engineering within the Genomic Medicine Center at Children's Mercy Hospital. His research focuses on producing patient-derived cellular models to develop functional precision medicine. He talks about using personalized antisense oligonucleotides to reverse disease phenotypes in organoid models of Duchenne muscular dystrophy. He also discusses his lab's personal connections to the rare disease community and the opportunities for collaborations with clinicians at Children's Mercy. Lees meer
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Ep. 290: “ISSCR 2025: Illuminating the Future” Featuring Drs. Valentina Greco, Kathryn Cheah, and Eugenia Piddini
18 maart 2025 · 1 uur 22 min
Dr. Valentina Greco is the President of the International Society for Stem Cell Research (ISSCR), and Professor of Genetics and Co-Chair of the Status of Women in Medicine at Yale University. Dr. Kathryn Cheah is an ISSCR Program Committee Co-Chair and Emeritus Professor and Chair of Biochemistry at Hong Kong University. Dr. Eugenia Piddini is also an ISSCR Program Committee Co-Chair and Professorial Research Fellow in Cell Biology and School Research Director at the University of Bristol. Lees meer
They talk about the upcoming ISSCR 2025 meeting in Hong Kong from June 11-14, 2025. They discuss the meeting's global focus, program highlights, opportunities for early-career researchers, and what they're looking forward to in Hong Kong.
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Ep. 289: “Heart-Forming Organoids” Featuring Dr. Robert Zweigerdt
4 maart 2025 · 1 uur 27 min
Dr. Robert Zweigerdt is a Principal Investigator at Hannover Medical School, where his lab focuses on cardiac differentiation and the scalable culture of PSCs. He talks about regulating the lineage-specific differentiation of hPSCs and generating heart-forming organoids that mirror developmental cardiogenesis. He also discusses the importance of mentorship and the benefits of an international research group. Lees meer
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Ep. 288: “Cerebellar Organoids” Featuring Dr. Giorgia Quadrato
18 februari 2025 · 1 uur 22 min
Dr. Giorgia Quadrato is Assistant Professor of Stem Cell and Regenerative Medicine at the University of Southern California. Her research focuses on brain developmental and neural organoids. She talks about protocols for generating cerebellar organoids, including those with functional Purkinje cells. She also discusses a transcriptomic atlas of neural organoids and the stem cell research landscape in California. Lees meer
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Ep. 287: “Blood Development” Featuring Drs. Andrew Elefanty and Elizabeth Ng
4 februari 2025 · 1 uur 29 min
Drs. Andrew Elefanty and Elizabeth Ng are Senior Principal Investigator and Principal Investigator, respectively, at the Murdoch Children's Research Institute. In the Blood Development group, they aim to develop innovative cellular therapies for blood and cartilage-related diseases. They talk about their recent study deriving and transplanting HSCs, their work on reporter lines, and their collaborative lab setup. Lees meer
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Ep. 286: “Neural Lineage Identity” Featuring Dr. Marius Wernig
21 januari 2025 · 1 uur 24 min
Dr. Marius Wernig is a Professor of Pathology and a Co-Director of the Institute for Stem Cell Biology and Regenerative Medicine at Stanford University, where his research interests include direct reprogramming and neurological disease modeling. He talks about his early work reprogramming neuronal cells from fibroblasts, adopting iPSCs, and growing his lab. He also discusses his recent research on cell therapy for brain and skin diseases, as well as his musical talents outside of the lab. Lees meer
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Ep. 285: “Funding the Future” Featuring Dr. Jonathan Thomas
7 januari 2025 · 1 uur 32 min
Guest:
Dr. Jonathan Thomas "JT" is the President and CEO of the California Institute for Regenerative Medicine (CIRM), an organization that provides funding for stem cell research with the purpose of accelerating treatments for patients in need. He talks about working to ensure diversity in clinical trials and developing treatments that are affordable and accessible to patients. He also discusses the progress during the twenty years since CIRM's inception, training the next generation of scientists, and balancing support for basic and clinical research. (41:03)
Featured Products and Resources: Lees meerRegister now for ISSCR 2025 in Hong Kong!
Cell Quality Attributes of Human Pluripotent Stem CellsThe Stem Cell Science Round Up
Regulating Naive Pluripotency – Scientists used a targeted rapid protein degradation system to show that GABPA is a master pluripotency regulator. (1:36)
Skin Wound Healing – A spatiotemporal atlas of human skin wound tissues identifies FOSL1 as a critical driver of re-epithelialization. (11:50)
Bone Marrow Stem Cell Niches – The bone marrow niche orchestrates hierarchy in stem cells and immune tolerance. (20:49)
Synthetic Organizer Cells – Synthetic organizer cells self-assemble around stem cells and produce morphogens. (30:50)
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Ep. 284: “Organ Chip Engineering” Featuring Dr. Milica Radisic
10 december 2024 · 1 uur 22 min
Dr. Milica Radisic is a Professor and Canada Research Chair at the University of Toronto. Her lab uses organ-on-a-chip engineering to mimic physiology of the heart, kidney, and vasculature for the purpose of modeling human disease and discovering more effective drugs. In this episode, she talks about the challenges of studying the heart and strategies to mature cardiomyocytes. She also discusses using macrophages to vascularize heart-on-a-chip platforms and enhance cardiac tissue function, sustainability considerations for microfluidic chips, and how these disease models can reduce the use of lab animals. Finally, she talks about starting a company to commercialize her lab's cardiac chip platform, the landscape for women entrepreneurs, and advice from her mentor, Dr. Bob Langer. Lees meer
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Ep. 283: “Molecular Hematopoiesis” Featuring Dr. Cynthia Dunbar
3 december 2024 · 1 uur 30 min
Dr. Cynthia "Cindy" Dunbar is National Institutes of Health (NIH) Distinguished Investigator and Chief of the Translational Stem Cell Biology Branch at the National Heart, Lung, and Blood Institute of the NIH. She talks about using macaques to study hematopoiesis and aging, and the challenges and considerations for using these models. She also discusses her collaborative study transplanting iPSC-derived cardiomyocytes into rhesus macaques, as well as the NIH's unique research environment and her musical talents outside of the lab. Lees meer
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Ep. 282: “Whole-Body Regeneration” Featuring Dr. Mansi Srivastava
26 november 2024 · 1 uur 34 min
Dr. Mansi Srivastava is Professor of Organismic and Evolutionary Biology at Harvard University and Curator of Invertebrate Zoology at the Harvard Museum of Comparative Zoology. Her lab uses distantly related species to study evolution and regeneration. She talks about establishing Hofstenia miamia, or the three-banded panther worm, as a model system. She also discusses her lab's work on adult stem cell lineage tracing and whole-body regeneration in Hofstenia, as well as her scientific outreach efforts. Lees meer
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Ep. 281: “Fertility Treatments” Featuring Drs. Dina Radenkovic and Bruna Paulsen
12 november 2024 · 1 uur 29 min
Drs. Dina Radenkovic and Bruna Paulsen are Co-Founder & CEO and VP of Manufacturing and Therapeutic development at Gameto, a biotech company developing treatment solutions to improve women's reproductive health. Their lead platform, Fertilo, uses ovarian support cells to mature oocytes outside of the body with the goal of making IVF and egg freezing shorter, safer, and more effective. Lees meer
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Ep. 280: “Liver Regeneration” Featuring Dr. Meritxell Huch
29 oktober 2024 · 1 uur 25 min
Dr. Meritxell Huch is a Scientific Director at the Max Planck Institute of Molecular Cell Biology and Genetics and an Honorary Professor at the Technical University of Dresden. Her research focuses on liver and pancreas organoid models. She discusses a protocol for liver mesenchyme and ductal cell organoid co-culture and generating bipotent stem cells from the liver. She also tells her story of moving throughout Europe to pursue her scientific passions. Lees meer
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Ep. 279: “Direct Reprogramming” Featuring Dr. Samantha Morris
22 oktober 2024 · 1 uur 28 min
Dr. Samantha Morris is an Associate Professor of Medicine at Brigham and Women's Hospital and Associate Professor of Systems Biology at Harvard Medical School. She talks about dissecting and manipulating the genetic pathways that regulate cell identity. She discusses tools to measure cell fate transitions and incorporating in silico and in vitro experiments. Lees meer
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Ep. 278: “Stembryo Engineering” Featuring Dr. Alfonso Martinez Arias
15 oktober 2024 · 1 uur 31 min
Dr. Alfonso Martinez Arias is the CREA Research Professor in the Department of Systems Bioengineering of the Universitat Pompeu Fabra in Barcelona. He talks about his path to developmental biology research and developing gastruloids to model human development. He also discusses standards for embryo models and his recent research on hematopoiesis. Lees meer
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Ep. 277: “Lung Development” Featuring Dr. Behzad Yeganeh
1 oktober 2024 · 1 uur 15 min
Dr. Behzad Yeganeh is an Associate Scientist at the Children's Hospital of Eastern Ontario Research Institute and the University of Ottawa. His work focuses on lung development and injury. He talks about neonatal lung diseases and the mechanisms that regulate autophagy and apoptosis. Lees meer
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Ep. 276: “Musculoskeletal Disorders” Featuring Dr. Dmitriy Sheyn
17 september 2024 · 1 uur 38 min
Dr. Dmitriy Sheyn is an Associate Professor in the Department of Orthopedics and Regenerative Medicine Institute at Cedars-Sinai Medical Center. His lab focuses on the development of stem cell therapies for multiple musculoskeletal disorders caused by acute injuries and aging. He talks about ways to model disc degeneration and tendon injuries. He also discuses his lab's work on tendon differentiation and the mechanisms of low back pain. Lees meer
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Ep. 275: “Liver Organogenesis” Featuring Dr. Ludovic Vallier
3 september 2024 · 1 uur 12 min
Dr. Ludovic Vallier is the W3 Einstein Strategic Professor for Stem Cells in Regenerative Therapies at the Berlin Institute of Health and a Max Planck Fellow at the Max Planck Institute for Molecular Genetics. His lab uses stem cells to model embryonic development in vitro and to produce liver cells with an interest for cell therapy. He talks about modeling non-alcoholic fatty liver disease and his lab's pivot to SARS-CoV-2 research early in the pandemic. He also discusses how iPSCs could be used to regenerate the liver after injury. Lees meer
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Ep. 274: “Brain Organoids” Featuring Dr. Ziyuan Guo
20 augustus 2024 · 1 uur 20 min
Dr. Ziyuan Guo is an Assistant Professor of Pediatrics at the Center for Stem Cell & Organoid Medicine at Cincinnati Children's Hospital. He talks about in vivo reprogramming and cell and gene therapy in neurodevelopmental and neurodegenerative disorders. He also discusses assembloids to model the blood-brain barrier and strategies for organoid vascularization. Lees meer
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Ep. 273: “Hematopoiesis and Cancer” Featuring Dr. Irving Weissman
6 augustus 2024 · 1 uur 51 min
Dr. Irving Weissman is the Virginia and Daniel Ludwig Professor of Clinical Cancer Research and Professor of Pathology and Developmental Biology at Stanford University. Dr. Weissman was the first scientist to identify and isolate mammalian blood-forming stem cells in mice, and his work has contributed to the understanding of how a single hematopoietic stem cell can give rise to specialized blood cells. He talks about developing new treatments for metastatic breast cancer and severe combined immunodeficiency. He also discusses myeloid bias in aging and strategies for commercializing new therapies. Lees meer
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Ep. 272: “Live at ISSCR 2024: Stem Cell Research in Space” Featuring Drs. Davide Marotta and Catriona Jamieson
23 juli 2024 · 59 min
Dr. Davide Marotta is the Program Director for In-Space Biomanufacturing at the International Space Station National Laboratory. Dr. Catriona Jamieson is the Director of the Sanford Stem Cell Institute at the University of California, San Diego. In this special episode recorded in front of a live audience at ISSCR 2024 in Hamburg, Germany, they talk about the opportunities and challenges of working with stem cells in a microgravity environment, and what this could mean for the future of stem cell-based therapies. They discuss the challenges of culturing cells in space, the need for risk reduction and collaboration, and how microgravity affects stem cell growth and aging. They also discuss the opportunities that come with the growing popularity of private spaceflight. Lees meer
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Ep. 271: “Skin Regeneration” Featuring Dr. Valentina Greco
9 juli 2024 · 1 uur 21 min
Dr. Valentina Greco is the Carolyn Walch Slayman Professor of Genetics and Co-Chair of the Committee on the Status of Women in Medicine at Yale University. Her research focuses on tissue homeostasis in the face of continuous cellular turnover, frequent injuries, and spontaneous mutations. She talks about her research on skin and hair follicle stem cells, the role of imaging techniques, and bridging science and art. She also discusses disease modeling and building an inclusive lab culture. Lees meer
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Ep. 270: “Microvascular Regeneration” Featuring Dr. Sara Vasconcelos
25 juni 2024 · 1 uur 20 min
Dr. Sara Vasconcelos is a Senior Scientist and the John Kitson McIvor Endowed Chair in Diabetes Research at University Health Network. She is also an Associate Professor at the Institute of Biomedical Engineering at the University of Toronto. Her lab studies microvascular regeneration in cardiovascular diseases and diabetes, and are working to develop personalized patient-derived organ-chip models for drug screening and other applications. In this episode, she talks about modeling cardiac fibrosis and studying pancreatic islet vasculature. She also discusses working with microchips and with large animal models. Lees meer
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Ep. 269: “iPSC Technology” Featuring Dr. Sebastian Diecke
11 juni 2024 · 1 uur 24 min
Dr. Sebastian Diecke is a Group Leader and Stem Cell Core Director at the Max Delbrück Center, where his research focuses on iPSCs and organoid models. He talks about the early days of iPSC research, developing organoids from endangered rhinoceros, and modeling Huntington's and other diseases. Lees meer
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Ep. 268: “Tissue Formation” Featuring Dr. Shukry Habib
28 mei 2024 · 1 uur 15 min
Dr. Shukry Habib is an Associate Professor in the Department of Biomedical Sciences at the Université de Lausanne. His lab works at the intersection of stem cell biology, biophysics, and tissue engineering to investigate how tissues form. He talks about developing a transplantable bandage for bone repair and the role of Wnt signaling and cytonemes in development. Lees meer
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Ep. 267: “Embryo Morphogenesis” Featuring Dr. Shankar Srinivas
14 mei 2024 · 1 uur 25 min
Dr. Shankar Srinivas is a Professor of Developmental Biology in the Department of Physiology Anatomy and Genetics based in the Institute for Developmental and Regenerative Medicine at the University of Oxford. He is also a Zeitlyn Fellow and Tutor in Medicine at Jesus College. Using mouse and human embryos as model systems, his group looks at the control of patterning and morphogenesis during the establishment of the anterior-posterior axis, gastrulation, and early cardiogenesis. He discusses how tissues respond to forces during early development, characterizing cardiac progenitors, and his experience training internationally. Lees meer
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Ep. 266: “From Stem Cells to Cortical Circuits” Featuring Dr. Pierre Vanderhaeghen
30 april 2024 · 1 uur 24 min
Dr. Pierre Vanderhaeghen is a Professor and Principal Investigator at VIB-KU Leuven Center for Brain & Disease Research. His lab studies the mechanisms of cortical development and brain evolution. He talks about species-specific neuronal development, human neuron excitability, and playing in a rock cover band! Lees meer
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Ep. 265: “RNA Glycosylation” Featuring Dr. Ryan Flynn
16 april 2024 · 1 uur 30 min
Dr. Ryan Flynn is a Principal Investigator at Boston Children's Hospital and an Assistant Professor in the Stem Cell and Regenerative Biology Department at Harvard University. His lab explores the interface between RNA and glycans. He talks about the discovery of glycoRNA and the chemistry of the RNA-glycan connection. He also discusses the effects of glycans on stem cell function and deciding between a career in medicine and basic science. Lees meer
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Ep. 264: “Planarian Regeneration” Featuring Dr. Blair Benham-Pyle
2 april 2024 · 1 uur 19 min
Dr. Blair Benham-Pyle is an Assistant Professor at Baylor College of Medicine. She talks about how multipotent cells in Schmidtea mediterranea enable whole-body regeneration. She also discusses the effects of the mechanical environment on stem cell fate. Lees meer
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Ep. 263: “ISSCR 2024: The Global Stem Cell Event” Featuring Drs. Amander Clark, Agnete Kirkeby, and Malin Parmar
19 maart 2024 · 1 uur 12 min
Dr. Amander Clark is the President of the International Society for Stem Cell Research (ISSCR) and Founding Director of the Center for Reproductive Science, Health, and Education at the University of California, Los Angeles. Dr. Agnete Kirkeby is a Program Chair of the ISSCR Annual Meeting, Associate Professor at Lund University and the University of Copenhagen, and Group Leader at the Novo Nordisk Foundation Center for Stem Cell Biology – reNEW. Dr. Malin Parmar is a Program Chair of the ISSCR Annual Meeting, Professor at Lund University, and a New York Stem Cell Foundation – Robertson Investigator. They talk about the upcoming ISSCR 2024 meeting in Hamburg, Germany from July 10-13, 2024. They discuss the meeting's clinical focus, spotlight and plenary sessions, and opportunities for students and postdocs. Lees meer
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Ep. 262: “Glia in the Gut” Featuring Dr. Marissa Scavuzzo
5 maart 2024 · 1 uur 15 min
Dr. Marissa Scavuzzo is an HHMI Hanna H. Gray Fellow at Case Western Reserve University School of Medicine. Her research focuses on enteric glia regulation in the healthy and diseased gut. She talks about how glial cell subtypes affect intestinal motility and her experience receiving NYSCF and HHMI fellowships. She also talks about bringing science to underserved schools in Cleveland. Lees meer
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Ep. 261: “Building Neuromuscular Tissues” Featuring Dr. Ritu Raman
20 februari 2024 · 1 uur 17 min
Dr. Ritu Raman is the d’Arbeloff Career Development Assistant Professor of Mechanical Engineering at MIT, where her lab uses robotics and tissue engineering to treat muscle loss. She talks about light-activated muscle grafts, magnetic microparticles to control forces exerted on cells, and strategies for science communication. Lees meer
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Ep. 260: “Synchronized Tissue Regeneration” Featuring Dr. Shiri Gur-Cohen
6 februari 2024 · 1 uur 24 min
Dr. Shiri Gur-Cohen is an Assistant Professor of Medicine in the Division of Regenerative Medicine at UC San Diego. Her lab studies epithelial stem cells throughout their lifetimes. She talks about lymphatics in the intestinal stem cell niche, 3D imaging techniques, and sharing her science with a wider audience. Lees meer
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Ep. 259: “Regenerative Neurobiology” Featuring Dr. Malin Parmar
23 januari 2024 · 1 uur 13 min
Dr. Malin Parmar is a Professor at Lund University and a New York Stem Cell Foundation – Robertson Investigator. Her research aims to understand cell fate specification in the developing brain and in human neural progenitor cells using cell-based models of neuronal differentiation. She talks about using assembloids to model the dopaminergic system, direct reprogramming somatic cells into induced neurons, and developing ESC-derived dopamine progenitor cells to treat Parkinson's disease. Lees meer
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Ep. 258: “The Musculo-Skeletal Axis” Featuring Dr. Olivier Pourquié
9 januari 2024 · 1 uur 16 min
Dr. Olivier Pourquié is the Frank Burr Mallory Professor of Pathology and Professor in the Department of Genetics at Harvard Medical School. His work focuses on the segmentation clock and the development of muscles and vertebrae. He talks about studying somitogenesis in vitro and his work on brown fat development. Lees meer
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Ep. 257: “Retinal Regeneration” Featuring Drs. Hwee Goon Tay and Beau Fenner
12 december 2023 · 1 uur 30 min
Dr. Hwee Goon Tay is an Assistant Professor at the Duke-National University of Singapore Medical School and Dr. Beau Fenner is an Ophthalmologist at the Singapore National Eye Centre. Their work focuses on cell therapy for degenerative retinal diseases. They talk about strategies to slow degeneration and potentially restore vision. Lees meer
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Ep. 256: “Epigenetics and Reprogramming” Featuring Dr. Jose Polo
28 november 2023 · 1 uur 22 min
Dr. Jose Polo is a Professor of Epigenetics and the Director of the Centre for Epigenetics at the University of Adelaide. He is also a Professor in the Department of Anatomy and Developmental Biology at Monash University. His lab studies the transcriptional and epigenetic mechanisms that govern cell identity. He talks about his team's work on cell fate, iBlastoids, and placental models for SARS-CoV-2. Lees meer
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Ep. 255: “Pathway to the Clinic” Featuring Drs. Stefan Irion and Viviane Tabar
14 november 2023 · 1 uur 5 min
Dr. Stefan Irion is the Chief Scientific Officer of BlueRock Therapeutics and Dr. Viviane Tabar is the Chair of the Department of Neurosurgery at Memorial Sloan Kettering Cancer Center. In this special episode, recorded in front of a live audience in New York, they talk about their work on BlueRock's clinical trial for bemdaneprocel — a stem cell-derived investigational cell therapy for Parkinson's disease. They also discuss what's next for cell therapy and diversity in science and in patients. Lees meer
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Ep. 254: “Muscle Regeneration” Featuring Dr. Helen Blau
31 oktober 2023 · 1 uur 17 min
Dr. Helen Blau is the Donald E. and Delia B. Baxter Foundation Professor and Director of the Baxter Laboratory for Stem Cell Biology at Stanford University. Dr. Blau’s research focuses on the basic molecular mechanisms of stem cells and muscle and their application to aging, regenerative medicine, and disease. Her lab aims to understand and apply biology to improve quality of life, and their current primary focus is on understanding the gerozyme 15-PGDH. She talks about the roles of NSAIDs and CD47 in muscle regeneration. She also discusses growing cultured meat and writing a children's book! Lees meer
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Ep. 253: “Heart Failure Genes” Featuring Dr. Roger Foo
17 oktober 2023 · 1 uur 18 min
Dr. Roger Foo is the Zayed bin Sultan Al Nahyan Professor of Medicine and Head of the Cardiovascular Research Institute at the National University of Singapore. His lab investigates the molecular mechanisms that regulate cardiac biology and disease. He talks about the genetics of heart disease and the roles of circular RNAs. Lees meer
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Ep. 252: “Organ-on-a-Chip” Featuring Dr. Bas Trietsch
3 oktober 2023 · 1 uur 24 min
Dr. Bas Trietsch is the Chief Technology Officer and Co-Founder at Mimetas, a company working to contribute to groundbreaking therapies with their screenable, physiologically relevant 3D human disease models. He talks about tissue-relevant models for drug discovery, and how organ-on-a-chip technology can help address scalability and reproducibility. Lees meer
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Ep. 251: “Post-Implantation Blastoids” Featuring Drs. Thorold Theunissen and Rowan Karvas
19 september 2023 · 1 uur 21 min
Dr. Thorold Theunissen is an Assistant Professor of Developmental Biology at Washington University in St. Louis investigating the molecular basis of pluripotency, the mechanisms of trophoblast development, and the generation of stem cell-based embryo models. Lees meer
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Ep. 250: “Blastoid Development and Implantation” Featuring Dr. Nicolas Rivron
5 september 2023 · 1 uur 37 min
Dr. Nicolas Rivron is a Principal Investigator at the Institute of Molecular Biotechnology of the Austrian Academy of Sciences in Vienna. His group recreates embryonic development using mammalian stem cells in a dish to better understand the encoded principles of self-organization. He talks about building human blastoid models and using them to study implantation. He also discusses differences in development between mice and humans, trophectoderm stem cells, and an ethical framework for embryo models. Lees meer
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Ep. 249: “Live at NYSCF: Overcoming Obstacles in Stem Cell Research” Featuring Drs. Laura Andres-Martin, Daniel Paull, and Raeka Aiyar
22 augustus 2023 · 1 uur
Dr. Laura Andres-Martin is a Research Investigator, Oncology, Dr. Daniel Paul is the Senior VP, Discovery & Platform Development, and Dr. Raeka Aiyar is the VP, Scientific & DEIB Outreach at the New York Stem Cell Foundation (NYSCF). This episode was recorded live and in-person at the NYSCF Research Institute. The panelists talk about NYSCF's approach to automation, their women's reproductive cancer initiative, and promoting inclusion and belonging in science. They also talk about Founder Susan Solomon's legacy and future plans to break down barriers in stem cell research. Lees meer
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Ep. 248: “Biomaterials and Tissue Engineering” Featuring Dr. Nathaniel Huebsch
8 augustus 2023 · 1 uur 14 min
Dr. Nathaniel Huebsch is an Assistant Professor of Biomedical Engineering at Washington University in St. Louis. His lab focuses on understanding how mechanical cues originating at cell-cell and cell-extracellular matrix contacts influence signaling and fate. They are especially interested in how those cues affect heart development and disease. He talks about cardiac models and cardiomyocyte maturity. Lees meer
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Ep. 247: “Neurological Disorders” Featuring Dr. Thomas Durcan
25 juli 2023 · 1 uur 5 min
Dr. Thomas Durcan is an Associate Professor and Director of the Early Drug Discovery Unit at the Montreal Neurological Institute. He oversees a team of 40+ research staff and students, committed to applying patient-derived stem cells towards the development of phenotypic discovery assays and 3D neuronal organoid models for neurodegenerative and neurodevelopmental disorders. He talks about modeling sporadic ALS in a dish, partnering with the Michael J. Fox Foundation, and promoting open science. Lees meer
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ISSCR 2023: On the Ground
11 juli 2023 · 42 min
In June 2023, we attended ISSCR 2023, the annual meeting of the International Society for Stem Cell Research, in Boston. We spoke with delegates about their research and impressions of the meeting, including their reasons for attending, what they were most looking forward to, and the most memorable research presented. Lees meer
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Ep. 245: “Cellular Diversity” Featuring Dr. Thomas Zwaka
27 juni 2023 · 1 uur 19 min
Dr. Thomas Zwaka is the Director of the Huffington Center for Cell-Based Research in Parkinson's Disease and a Professor of Regenerative and Developmental Biology at the Icahn School of Medicine at Mount Sinai. His research focuses on fundamental questions surrounding stem cell biology, including how to reverse the process of differentiation and “re-program” any given cell type into a pluripotent stem cell. Lees meer
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ISSCR 2023: Day 4
18 juni 2023 · 37 min
In June 2023, Daylon and Arun attended the International for Stem Cell Research's (ISSCR) annual meeting in Boston, Massachusetts, and recorded daily episodes discussing highlights of the final day of the meeting.
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ISSCR 2023: Day 3
17 juni 2023 · 30 min
In June 2023, Daylon and Arun attended the International Society for Stem Cell Research's (ISSCR) annual meeting in Boston, Massachusetts, and recorded daily episodes discussing highlights of the third day of the meeting.
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ISSCR 2023: Day 2
16 juni 2023 · 37 min
In June 2023, Daylon and Arun attended the International Society for Stem Cell Research’s (ISSCR) annual meeting in Boston, Massachusetts, and recorded daily episodes discussing highlights of the second day of the meeting.