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364 afleveringen, van nieuw naar oud
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A journey from personal to public: Digital health passports today
29 oktober 2024 · 34 min
A digital health passport is an app, or online certification, that displays a traveller’s health or vaccination record. It can save lives, on both private and public levels. Lees meer
In today’s pharmaphorum podcast, web editor Nicole Raleigh speaks with Matt Hollingsworth, co-founder and CEO of Carta Healthcare, a company seeking to support the healthcare data registry market by transforming a previously manual clinical data abstraction process.
Hollingsworth discusses his own, very personal experiences that led to Carta Healthcare’s foundation and progressed its work, as well as the comfort that can be provided patients with chronic diseases – including congenital heart defects – with digital health passports, offering an information safety net for them whilst travelling, circumventing the need to carry veritable folders full of printed health records.
Diving into the what’s what of EHRs, AI’s role in digital health passports, and the pros and cons of a generally digital future, technology is nevertheless very much in our health futures, explains Hollingsworth.
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Access to genomic surveillance: Open science and public health
16 oktober 2024 · 18 min
The pandemic served as a catalyst for a revolution in genomic surveillance for tracking pathogens. The technology proved vital in aiding understanding of the evolution of and spread of virus in real time to inform public health measures, ultimately accelerating drug and vaccine development. Lees meer
In today’s podcast, web editor Nicole Raleigh speaks with Dr Evan Floden, CEO and co-founder of Seqera, a data orchestration and genomics analysis company, about barriers of entry to genomic surveillance in public health labs and how these can be lowered to support future bioinformaticians, aiding acceleration and quality and accuracy in R&D.
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Advancing Precision Care For All
9 oktober 2024 · 28 min
Precision medicine is oft spoken about these days, as it is finally addressing the elephant in the room: one size – or, more appropriately, one dose – does not fit all. Precision medicine hones in on treatment of the individual, rather than just the disease, focusing on the reality that each patient is biologically different. Personalisation is very much key. Lees meer
In a new pharmaphorum podcast, web editor Nicole Raleigh spoke with Hakim Yadi, PhD, OBE, and CEO and co-founder of Closed Loop Medicine, ahead of his appearance at Frontiers Health next week, 17th-18th October.
Closed Loop Medicine is a TechBio company developing prescription combination drug plus software products, with the aim of bring forward the promise of precision medicine. From personalised dosing to the applicability of this approach to the GLP-1 trend in obesity treatment, the conversation covers recent collaborations and harks back to discussions at the Galien Forum earlier in 2024, honing in on the importance of workflow and cost considerations, also.
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Investment outlook: Key takeaways from LSX USA
4 oktober 2024 · 33 min
Investment and strategic partnerships are the lifeblood of innovation in healthcare, driving groundbreaking discoveries and accelerating the development of life-changing therapies. And so, it was no surprise that the 2024 LSX USA Congress in Boston attracted life sciences innovators and decision-makers from around the world, eager to explore the latest trends shaping the industry. Lees meer
Among those attendees was pharmaphorum’s editor-in-chief, Jonah Comstock, who took to the floor to uncover the trends and talking points set to influence investment decisions in the coming months.
In this special episode of the pharmaphorum podcast, Jonah sat down with Deep Dive editor Eloise McLennan to discuss key takeaways from the LSX conference. From evolving investment trends like AI in biotech and digital to emerging areas such as precision psychiatry, they explore the cautiously optimistic investment landscape, the delicate balance between early- and late-stage investments, and the importance of building honest, productive relationships across the healthcare ecosystem.
Tune in to hear their in-depth analysis of the latest investment and partnership trends shaping the future of healthcare innovation.
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Oncology today: Eversana and pharmaphorum at ESMO 2024
25 september 2024 · 19 min
The ESMO congress always disseminates the latest results of cancer research, a vibrant gathering and sharing of the latest data, communicating the next promising steps in oncological scientific development, ever seeking to address unmet patient needs. Lees meer
So it was that pharmaphorum Web Editor Nicole Raleigh found a quiet spot onsite in Barcelona this year to catch with experts from EVERSANA and discuss their takeaways from the 2024 conference. Tune in to hear more from: Ann Marie Robertson, Chief Commercial Officer, EVP, EVERSANA COMPLETE Oncology, EVERSANA; Barry Vucsko, Senior Vice President, Client Services and Business Development Leader, EVERSANA INTOUCH; Vanitha Sankaran, VP, Medical Strategy, EVERSANA INTOUCH; and Gurdip Daffu, PhD, VP, Medical Strategy (Oncology), EVERSANA INTOUCH.
From the unique to the specifics of antibody-drug conjugates (ADCs) and advancements in women’s cancers, to the proliferation of AI and where it’s all going, and from diagnostics to excitement and hope at what’s on the cusp and what’s yet to come – the sense of bated breath potential is palpable.
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Medicare drug pricing negotiations: What comes next?
12 september 2024 · 29 min
Last month, the US Centers for Medicare and Medicaid Services released the negotiated prices for the first 10 drugs subject to the drug negotiation provisions in the Inflation Reduction Act. The industry has been waiting with bated breath to see these prices, as they give the first real indication of how impactful this unprecedented legislation will be for pharma’s bottom line. Lees meer
But this latest release of information raises as many questions as it answers, and on today’s podcast host Jonah Comstock is joined by Alice Valder Curran, a partner at Hogan Lovells and a healthcare policy expert, for a broad ranging discussion of some of the next steps and consequences – intended or otherwise – of this legislation.
They talk about the many challenges CMS is likely to face in operationalising these prices and how much of the savings is likely to find its way to patients when the dust settles. They also discuss the prices themselves, why they aren’t lower, and just how low they really are, contextually. Additionally, they discuss some of the downstream consequences still to come from the IRA, including possible effects on oncolytics and the generics market.
For the pharma industry, the IRA drug pricing negotiation provision is shaping up to be one of the most consequential political stories of the decade. Tune in for a lively and in-depth discussion of what those consequences might look like.
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The Life Sciences Generative AI Council and a sustainable technological future
5 september 2024 · 17 min
The Life Sciences Generative AI Council aims to bring together the best minds in pharma, academia, and technology to advance the use of GenAI in life sciences R&D, seeking through pinpointing and showcasing repeatable use cases to shape the targeted use of next-generation artificial intelligence and machine learning (AI-ML) innovation, particularly in the form of GenAI. Lees meer
In today’s pharmaphorum podcast, web editor Nicole Raleigh speaks with Manny Belabe, senior VP of customer success at ArisGlobal, about the Council and the role it seeks to play in furthering the success of GenAI in life sciences R&D.
Discussing also ArisGlobal’s LifeSphere NavaX GenAI features and functionality, Belabe notes too that a platform-centric development approach, based on common modules, can be leveraged to reduce data redundancy and general maintenance of that data.
At the present moment, however, there is also the pressing concern of sustainability in all sectors, and Belabe addresses practical issues around cooling infrastructure and space requirements for these technologies, as well.
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Can self-navigating ADCs replace chemotherapy in the future?
28 augustus 2024 · 20 min
In a new pharmaphorum podcast, web editor Nicole Raleigh speaks with Brian Fiske, chief scientific officer of Mythic Therapeutics, about minimising side effects for patients and the notion of patient-centred science.
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Structuring the unstructured: Deterministic AI and white box data cleanliness
20 augustus 2024 · 19 min
In a new pharmaphorum podcast, web editor Nicole Raleigh speaks with Jane Reed, director of life sciences at Linguamatics, an IQVIA company, to discuss some of the major barriers preventing researchers from accessing the data they need to advance drug discovery and development and address safety concerns – and just how AI technologies can assist. Lees meer
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People need to know how to use AI now
13 augustus 2024 · 31 min
With the implementation of advancing technologies in industry comes the parallel need for suitable upskilling of the workforce – but this doesn’t as yet always pan out, and in today’s pharmaphorum podcast COO of Enthought Mike Connell discusses the growing skills gap in R&D in life sciences and the 80/20 rule with web editor Nicole Raleigh, as well as the need for correct education of people and machines, both. Lees meer
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Chronic cough and the patient voice
6 augustus 2024 · 14 min
Chronic cough impacts up to 10% of the adult population and has a physical, psychological, and social impact on patients’ lives. Lees meer
Farrell Simon, chief commercial officer at Trevi Therapeutics, joins web editor Nicole Raleigh on the pharmaphorum podcast to discuss prioritising patients in clinical and commercial development, with an especial focus on chronic cough.
There are currently no approved therapies in either the US or the UK for what is a highly disruptive affliction, accompanied by a wide range of complications, which causes a significant burden on patients, caregivers, and healthcare systems.
Also discussing Trevi’s own work in the field, in particular a potential treatment for idiopathic pulmonary fibrosis (IPF), the conversation explores how to work more closely and holistically with patients in clinical development. Integrating the patient voice is, as Simon says, critical in clinical trial design. After all, the patient is the utmost stakeholder.
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Approaching the regulatory world with passion: CERs and EU MDR processes
31 juli 2024 · 22 min
In a new pharmaphorum podcast, web editor Nicole Raleigh speaks with Ethan Drower, co-founder and CEO of Cite Medical Solutions, a company providing full Clinical Evaluation Report (CER) services and industry literature review for European Union Medical Device Regulation (or EU MDR) processes. Lees meer
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Patient engagement throughout the product lifecycle
25 juli 2024 · 29 min
One of the things that makes patient engagement for pharma companies so challenging is that it's not something that can be added to one step of a process and then checked off the list. Real patient engagement needs to be integrated into processes every step of the way. Lees meer
In today's podcast, brought to you by Reverba, Reverba CEO Cheryl Lubbert joins host Jonah Comstock to walk through the steps of the product lifestyle and explore the role of the patient at each of those stages: from preclinical through commercialisation and beyond.
Lubbert discusses the relationship between patient engagement, patient activation, patient centricity, and patient co-creation. She gives a wealth of examples from her experience as a long-time leader in the pharma industry to give context to the many ways to incorporate patients and their feedback into product discovery, clinical trials, product development, launch, and post-launch.
Finally, at the end of the podcast Lubbert gets into a few other hot-button issues including diversity and representation, as well as AI and how it will affect patient engagement. Tune in for interesting and actionable tips about patient engagement in pharma.
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The empowerment of data and predictive outcome models
23 juli 2024 · 22 min
In today’s podcast, web editor Nicole Raleigh speaks with Carolyn Ward, director of clinical strategy at Particle Health Inc, a data transformation platform for healthcare, enabling organisations across the care continuum to turn medical records into actionable insights. Lees meer
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The burden of diabetic vision loss in the West
18 juli 2024 · 17 min
In today’s podcast, web editor Nicole Raleigh welcomes Dr Catherine Beech, CEO of Exonate, for a discussion on retinal vascular disease and a potential eye drop treatment for diabetic retinopathy and diabetic macular oedema, instead of invasive injections into the eye. Lees meer
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Tips for on-time tech transfers that stay below budget
18 juli 2024 · 25 min
When it comes to life sciences manufacturing, there's nothing quite so daunting as a tech transfer - moving a product from development to commercialisation, or to a new facility or CDMO, presents many obstacles that have to be well thought out and planned. Delivering a tech transfer on schedule that stays below budget is no easy feat, but with the right best practices it can be done. Lees meer
In today's podcast, brought to you by Lannett CDMO, Grant Brock, VP of operations at Lannett CDMO, and Frantz Maignan, Lannett CDMO's director of validation and tech services, join host Jonah Comstock for a deep dive into what challenges companies can encounter when it comes to tech transfers and some standout strategies for avoiding and surmounting those challenges.
The discussion includes the importance of thorough preparation and experimentation, good communication, and flexibility, and Brock and Maignan offer a few tips for choosing a manufacturing partner that can handle the unexpected bumps in the road that can crop up.
Tune in for a practical guide to an important and oft-overlooked aspect of pharma manufacturing.
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Clinical trial trends and the rise of site networks
11 juli 2024 · 29 min
We've recently passed the midpoint of 2024, so it's a good time to check in on trends – in this case, trends in the clinical trial space. Lees meer
In today's podcast, brought to you by Advanced Clinical, host Jonah Comstock is joined by Jason Casarella, EVP of business development and marketing at Advanced Clinical and Caroline Redecker, chief strategy officer at Advanced Clinical, to discuss some of the findings in their recently released clinical trends report.
One of the biggest trends in the report is the rise of clinical trial site networks, and Casarella and Redecker drill down on why that’s happening and what it means for investigators. They also discuss how patient recruitment is changing in light of both changing technology and infrastructures, and new expectations about representation and diversity.
The conversation also veers into biotech investment trends and how those impact clinical trials, as well as the rise of AI and the various use cases being found for it in clinical research. Tune in for a wide-ranging snapshot into the evolving world of clinical research.
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A spectrum of obesity requires precision
10 juli 2024 · 24 min
In this latest pharmaphorum podcast, web editor Nicole Raleigh speaks with Michael Kyle, chief medical officer at Currax Pharmaceuticals – a company working to advance a greater understanding of how to effectively treat obesity – about perceptions and options beyond the bounds of GLP-1s, including evolution of hypertension treatments. Lees meer
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The power and potential of regenerative medicine
2 juli 2024 · 20 min
The field of muscle stem cell research has been tangibly developing over the decades and in today’s pharmaphorum podcast wed editor Nicole Raleigh speaks with Dr Michael Rudnicki, co-founder and CSO of Satellos Biosciences, a company dedicated to developing novel therapeutics based on this science for those who live with Duchenne muscular dystrophy (DMD) and other degenerative muscle diseases. Lees meer
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Leveraging data and AI for clinical trial success
28 juni 2024 · 15 min
In today’s pharmaphorum podcast, Orr Inbar, co-founder and CEO of QuantHealth, a Tel Aviv-based AI-powered clinical trial design company, discusses how advances in data and AI can help.
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The future of fertility and the vaginal microbiome
25 juni 2024 · 25 min
In a new episode of the pharmaphorum podcast - recorded back in March, during Women’s History Month - web editor Nicole Raleigh spoke with Johan van Hylckama Vlieg, co-founder and chief scientific officer of Freya Biosciences, a Series A-financed, clinical stage, microbial immunotherapy company in women’s health, discussing the role of the vaginal microbiome in fertility, before he was due to speak at the first-of-its-kind Microbes in Women’s Health Congress in Copenhagen. Lees meer
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Sustainable innovation for patients, people, and planet
21 juni 2024 · 29 min
Sustainability is all important for the planet and its people, and in today’s podcast web editor Nicole Raleigh speaks with Harriet Lewis, director of public affairs and communications at Chiesi UK & Ireland, about how partnerships between the NHS and pharma industry can support the journey to more sustainable practices, from R&D and drug reimbursement to medicines and recycling. Lees meer
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The new frontier of microbiome-directed human health
18 juni 2024 · 31 min
The microbiome is ever more frequently spoken about of late, and so the pharmaphorum podcast invited Leo Grady, founder and CEO of Jona, to speak about at-home personal microbiome profiling, uncovering the relationship between human health and the gut. Lees meer
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Global medicines and the future outlook
13 juni 2024 · 29 min
In a conversation held earlier in the year as the four-year anniversary of the pandemic approached, the pharmaphorum podcast had as guest Murray Aitken, executive director of the IQVIA Institute for Human Data Science, to discuss the state of global medicines and the future outlook when it comes to research and development, and usage and spending appetites. Lees meer
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Purity, potency, and safety – affordably – in stem cell therapy
11 juni 2024 · 28 min
In a new episode of the pharmaphorum podcast, web editor Nicole Raleigh discusses stem cell therapy, and accessibility to and affordability of such treatment, with Rafael R Carazo Salas, founder and CEO of CellVoyant, an AI-first biotechnology company spun out from the University of Bristol. Lees meer
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The art of software
5 juni 2024 · 27 min
In this episode of the pharmaphorum podcast, web editor Nicole Raleigh speaks with Rob Pears, VP and head of automotive, manufacturing, and life sciences at Capgemini, which partners with companies to transform and manage their business by harnessing the power of technology. Lees meer
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Move over CAR-T: The potential of NK cells in cell therapy
30 mei 2024 · 35 min
On today’s podcast, Dr. Fred Aslan, CEO of Artiva Biosciences, joins host Jonah Comstock to talk more about this newer avenue in cell therapy. They discuss the potential of NK cells to provide effective allogeneic cell therapy, the potential of the therapy in auto-immune disease, and the importance of a robust manufacturing process that can get a high number of doses from a small amount of donated tissue. Lees meer
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Working for a mature form of genomic medicines
29 mei 2024 · 20 min
In a new episode of the pharmaphorum podcast, Rahul Kakkar, CEO of gene editing company Tome, speaks with web editor Nicole Raleigh about programmable genomic integration (PGI) technology.
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Challenges and opportunities in synthetic clinical trials
23 mei 2024 · 44 min
On today’s episode Web Sun, president and cofounder of Komodo Health and Tracy Mayne, SVP regulatory and life sciences research at Slipstream IT, talk about this trend, where the industry is now, and what they’re doing to move it along.
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The commercialisation of quantum science in pharma
21 mei 2024 · 26 min
In today’s podcast, web editor Nicole Raleigh speaks with PASQAL’S technical business developer Europe, Krisztian Benyo, PhD, about the pharma applications and commercialisation of quantum science.
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Conference report: Reuters Pharma Europe
16 mei 2024 · 37 min
In this special edition of the pharmaphorum podcast, the tables have turned as Jonah Comstock puts editors Eloise McLennan and Nicole Raleigh in the hot seat to discuss the biggest trends and talking points from last month’s Reuters Pharma Europe 2024 in Barcelona. Lees meer
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In vitro gametogenesis: the science has to be right, and it has to be safe
14 mei 2024 · 17 min
Today’s podcast sees web editor Nicole Raleigh speak with Dr Mark Leondires, founder and medical director at Illume Fertility, who shares his own journey and insights on In vitro gametogenesis (IVG).
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Proving ROI for digital endpoints
9 mei 2024 · 33 min
Jennifer Goldsack of DiME talks in this podcast about the ROI for digital endpoints for pharma. Data shows digital endpoints drives meaningful engagement with healthcare providers.
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Clinical trials: their design, location, and, potentially, their simulation
8 mei 2024 · 17 min
Clinical trials, their design and location, and these days their simulation, are the focus of today’s podcast with Dr Gen Li, founder and president of Phesi.
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Pace, acceleration, and precision are the name of the game
2 mei 2024 · 21 min
Security and privacy within biotech are critical points of consideration and discussion as the industry continues to innovate at speed, and it is such aspects that are central to today’s podcast with Zach Powers, chief information security officer at Benchling, the R&D cloud platform for the biotech industry. Lees meer
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Technology working as the puzzle piece to bring better outcomes to patients
30 april 2024 · 18 min
While at Reuters Pharma Europe in Barcelona the other week, pharmaphorum web editor Nicole Raleigh spoke with Florian Schnappauf, VP of enterprise commercial strategy at Veeva Europe, about commercial strategy and digitalising commercial operations.
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Is precision psychiatry possible?
25 april 2024 · 36 min
On today’s podcast, host Jonah Comstock is joined by Dr Amit Etkin, founder and CEO of Alto Neuroscience, a recently IPO'd biotech that wants to bring precision medicine to psychiatry. But what do we mean when we talk about precision, especially in a discipline like mental health that has historically involved a lot of objectivity? Lees meer
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Encouraging early engagement to revitalise Europe’s pharmaceutical landscape
23 april 2024 · 20 min
In an on-site interview at Reuters Pharma Europe in Barcelona, this week’s podcast saw Tommy Bramley, SVP of market access and healthcare consulting at Cencora, discuss revitalising Europe’s pharmaceutical landscape and leveraging legislation for health and competitiveness. Lees meer
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Predictions for AI in mental health in the coming year
18 april 2024 · 23 min
In a new episode of the pharmaphorum podcast, web editor Nicole Raleigh welcomes Dr Carl Marci, chief psychiatrist and managing director of mental health and neuroscience at OM1 to discuss predictions for AI in mental health in the coming year, as well as what might truly make a difference in the field and lessen the mental health crisis. Lees meer
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Fixing clinical trial data management
11 april 2024 · 27 min
It’s 2024 and in most clinical trials, data is still being moved from the EHR to the EDC manually – with employees reading data from one screen and typing it onto another. How did we get here? And how do we get past it? Lees meer
On today’s pharmaphorum podcast, host Jonah Comstock speaks with Iddo Peleg, CEO of Yonalink, about these very questions.
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Harnessing the velocity of biopharmaceutical advances
9 april 2024 · 18 min
On today's episode of the podcast CEO and co-founder of 908 Devices Kevin Knopp joins as guest, discussing how such acceleration is by virtue of technological advancements, including the buzzword artificial intelligence (AI) and machine learning when it comes to bioprocessing. Lees meer
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Conference report: Reuters Pharma USA
4 april 2024 · 38 min
Last week, pharmaphorum Editor in Chief Jonah Comstock traveled to Philadelphia for Reuters Pharma USA. On today’s podcast, he chats with guest host and Deep Dive Editor Eloise McLellan about his biggest takeaways from the two-day event.
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The future of AI: Machine learning working together with scientific expertise
2 april 2024 · 10 min
In a new episode of the pharmaphorum podcast recorded live on site at WIRED Health in London in March, web editor Nicole Raleigh spoke with Elise de Reus, co-founder of Cradle, the generative AI platform that helps scientists to design and program proteins. Lees meer
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Understanding the politics of drug pricing in the United States
28 maart 2024 · 36 min
Everyone says they want more affordable drugs for patients that need them, but people disagree quite a bit on who's to blame for the current status quo of sky-high prescription prices – not to mention how they might be corrected. Lees meer
To help unpack some of those trends and conflicting perspectives, Brandon Newman, CEO of healthcare analytics firm Xevant, joins host Jonah Comstock on today’s episode of the pharmaphorum podcast.
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Female leadership and lessening disease burden
26 maart 2024 · 15 min
As Women’s History Month comes to its final week, today’s podcast sees web editor Nicole Raleigh in conversation with Debra Weiss, COO of the Bill & Melinda Gates Medical Research Institute (Gates MRI), discussing her role as a female leader in the leader and the non-profit organisation’s work in developing novel biomedical interventions and lessening the burden of disease in LMICs. Lees meer
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The unique clinical trial challenges faced by digital therapeutics
21 maart 2024 · 28 min
On today’s podcast, host Jonah Comstock is joined by Meri Beckwith, cofounder of Lindus Health, a next-gen CRO that includes digital therapeutics among its specialties. They talk a little bit about often unseen difficulties of validating a digital therapeutic through a clinical trial. Lees meer
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The unmentionables: Challenging inequalities in women’s health
19 maart 2024 · 48 min
As Women’s History Month continues, pharmaphorum web editor Nicole Raleigh welcomed a group of expert individuals onto the podcast to discuss not just the inequalities in women’s health, but female leaders within life sciences, too. Lees meer
The guests included: Trine Bartholdy, chief innovation executive at the BioInnovation Institute (BII) in Denmark; Karin Lykke-Hartmann, CEO and founder of Notify Therapeutics; Julia Sand Skovsted, co-founder and CCO of Oasicare; and Maj Hedtjärn, Entrepreneur in Residence for the CurE-Me project.
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The next chapter for AI protein structure prediction
14 maart 2024 · 28 min
On today’s pharmaphorum podcast, Glen Gowers, cofounder of Basecamp Research, gets into the company’s recent pre-print paper and how it improves upon AlphaFold 2, the current gold standard for protein folding prediction.
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Avoiding the data swamp: The transformative power of AI
12 maart 2024 · 18 min
In the latest episode of the pharmaphorum podcast, host Nicole Raleigh speaks (virtually) with Nathan Clark, founder and CEO of Ganymede, a modern data platform and Cloud infrastructure for science, to discuss the evolving role of the Cloud in biopharma and some rather revolutionary tools in AI drug discovery. Lees meer
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How natural language processing can make a difference in pharma
7 maart 2024 · 23 min
On today’s podcast, host Jonah Comstock welcomes Jane Reed, director of life sciences at IQVIA NLP, the new name for recent IQVIA acquisition Linguamatics. Jane talks through some of these different technologies and use cases and describes how natural language processing has exciting potential in translating real-world conversations on social media into pharmaceutical adverse event reports. Lees meer