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290 afleveringen, van nieuw naar oud
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TWiP 40: Doctor, there's a worm in my eye!
17 mei 2012 · 1 uur 13 min
Hosts: Vincent Racaniello and Dickson Despommier Lees meer
Vincent and Dickson discuss loaiasis caused by the filarial nematode Loa loa.
Right-click to download TWiP #40 (52 MB .mp3, 73 minutes).
Links for this episode:
Albendazole therapy for US-bound refugees (NEJM)
Microfilaria of Loa loa (png)
Loa loa life cycle (png)
Letters read on TWiP 40
Contact
Send your questions and comments (email or mp3 file) to twip@twiv.tv.
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TWiP 39: I encyst, said the amoeba
26 april 2012 · 1 uur 25 min
Hosts: Vincent Racaniello and Dickson Despommier Lees meer
Vincent and Dickson review the biology and pathogenesis of the amoebae Naegleria fowlerii and Acanthamoeba castellani.
Links for this episode:
N. fowlerii life cycle (CDC)
N. fowlerii at Artful Amoeba
Naegleria and amoebic meningoencephalitis (MDPH)
First case of Naegleria PAM in Italy (Emerg Inf Dis)
N. fowlerii in well water (Emerg Inf Dis)
Recent N. fowlerii case in Minnesota (Clin Inf Dis)
Beat the holiday bug (Sydney Morning Herald)
Is your neti pot safe? (Dallas News)
Acanthamoeba keratitis fact sheet (CDC)
Letters read on TWiP 39
Contact
Send your questions and comments (email or mp3 file) to twip@twiv.tv.
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TWiP 38: How to Trichomonas
3 april 2012 · 1 uur 14 min
Hosts: Vincent Racaniello and Dickson Despommier Lees meer
Vincent and Dickson tackle the backlog of listener email, then consider the life cycle and pathogenesis of Trichomonas vaginalis, the flagellated protozoan transmitted by sexual contact.
Links for this episode:
T. vaginalis life cycle (jpg)
T. vaginalis hydrogenosome (jpg)
Letters read on TWiP 38
Contact
Send your questions and comments (email or mp3 file) to twip@twiv.tv.
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TWiP 37: Dracunculiasis
19 februari 2012 · 1 uur 42 min
Vincent and Dickson discuss the life cycle and pathogenesis of Dracunculus medinensis, the filarial nematode that causes dracunculiasis, or Guinea worm disease. Lees meer
Links for this episode:
Dracunculus emerging from foot (jpg)
Dracunculus medinensis life cycle (jpg)
Guinea worm - WHO
Guinea worm eradication - The Carter Center
War against Guinea worm (YouTube)
Caduceus vs staff of Asclepius
Vincent and Dickson - the dogs (jpg)
Letters read on TWiP 37
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TWiP 36: Trichuris and microbes plan a hatch
1 februari 2012 · 1 uur 9 min
Vincent and Dickson review how gut bacteria help establish T. muris in the large intestine of mice.
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TWiP 35: Malaria control with David Fidock
13 januari 2012 · 1 uur 17 min
Vincent and Dickson discuss control of malaria with their Columbia University colleague David Fidock.
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TWiP #34 - Up against the Wolbachia
13 december 2011 · 1 uur 31 min
Vincent and Dickson discuss control of malaria and filariasis with the bacterial endosymbiont Wolbachia.
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TWiP #33 - Hide and seek
24 november 2011 · 1 uur 28 min
Vincent and Dickson review an in silico pipeline for identifying molecular mimicry candidate proteins in the genomes of parasites, and catch up on listener email.
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TWiP #32: Evasive trypanosomes and schistosomes
8 november 2011 · 1 uur 30 min
Vincent and Dickson discuss immune evasion by the cruzain protease of T. cruzi, and novel tetraspanin antigens of S. japonicum.
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TWiP #31 - A malaria vaccine
21 oktober 2011 · 1 uur 10 min
Vincent and Dickson discuss the promising results of a phase III trial of a malaria vaccine in African children.
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TWiP #30 - Global infectious disease control with Charles Knirsch
15 september 2011 · 1 uur 25 min
Vincent and Dickson have a broad-ranging conversation with Charles Knirsch of Pfizer, Inc. about how public-private partnerships can function to control and eliminate infectious diseases.
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TWiP #29 - Neglected tropical diseases with Peter Hotez
23 augustus 2011 · 1 uur 5 min
Vincent and Dickson converse with Peter Hotez about global health, vaccinology, and neglected tropical diseases.
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TWiP #28 - Medical entomology with Robert W. Gwadz
26 juli 2011 · 1 uur 31 min
Vincent and Dickson discuss medical entomology with Robert W. Gwadz, Assistant Chief of the Laboratory of Malaria and Vector Research at NIAID.
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TWiP #27 - Trematodes
22 juni 2011 · 1 uur 17 min
Vincent and Dickson continue their discussion of trematodes, or flukes, which have a snail as a reservoir host.
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TWiP #26 - The schistosomes
27 mei 2011 · 1 uur 35 min
Vincent and Dickson take on the schistosomes, agents of a series of related diseases in humans referred to as schistosomiasis.
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TWiP #25 - Wuchereria bancrofti
28 april 2011 · 1 uur 7 min
Vincent and Dickson review Wuchereria bancrofti, the nematode that causes lymphatic filariasis, also known as elephantiasis.
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TWiP #24 - Onchocerca volvulus, a vector-borne, filarial nematode
31 maart 2011 · 1 uur 22 min
Vincent and Dickson discuss the life cycle and pathogenesis of Onchocerca volvulus, the vector-borne filarial nematode parasite that causes onchocerciasis, or river blindness.
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TWiP #23 - Strongyloides sterocoralis, a most unusual parasite
3 maart 2011 · 1 uur 43 min
Vincent and Dickson review the life cycle and pathogenesis of the world's most unusual parasite, Strongyloides stercoralis.
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TWiP 22 - Hookworm
9 februari 2011
Vincent and Dickson discuss possibly the most socially and politically important nematode of humans, the hookworm Ancylostoma duodenale and Necator americanus.
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TWiP #21 - The giant intestinal worm, Ascaris lumbricoides
20 januari 2011 · 1 uur 32 min
Vincent and Dickson review the biology and pathogenesis of Ascaris lumbricoides, one of the largest nematodes to infect humans.
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TWiP #20 - The whipworm Trichuris trichiura
17 december 2010 · 1 uur 29 min
Vincent and Dickson continue their discussion of nematodes with the whipworm Trichuris trichiura. Lees meer
Host links: Vincent Racaniello and Dickson Despommier
Links for this episode:
Trichuris trichiura adult female (jpg)
Trichuris trichiura adult male (jpg)
Trichuris trichiura in situ (jpg)
Trichuris trichiura life cycle (jpg)
Exploitation of the intestinal microflora by T. muris
Letters read on TWiP 20
Contact
Send your questions and comments (email or mp3 file) to twip@twiv.tv.
Subscribe (free)
Click here to receive an email notification when a new episode of TWiP is published
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TWiP #19 - Enterobius vermicularis, the pinworm
20 november 2010 · 1 uur 23 min
Vincent and Dickson move on to nematodes with a discussion of the pinworm Enterobius vermicularis. Lees meer
Host links: Vincent Racaniello and Dickson Despommier
Links for this episode:
Enterobius vermicularis adult female (jpg)
Enterobius vermicularis in appendix (jpg)
Enterobius vermicularis embryonated eggs (jpg)
Enterobius vermicularis life cycle (jpg)
Letters read on TWiP 19
Contact
Send your questions and comments (email or mp3 file) to twip@twiv.tv.
Subscribe (free)
Click here to receive an email notification when a new episode of TWiP is published.
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TWiP #18 - Cryptosporidium
27 oktober 2010 · 1 uur 20 min
Vincent and Dickson discuss the intracellular parasite Cryptosporidium, which causes diarrheal disease in most mammalian species. Lees meer
Host links: Vincent Racaniello and Dickson Despommier
Links for this episode:
Cryptosporidium parvum electron micrograph (jpg)
Cryptosporidium parvum meronts (jpg)
Cryptosporidium parvum life cycle (jpg)
Cryptosporidium page at CDC
Letters read on TWiP 18
Contact
Send your questions and comments (email or mp3 file) to twip@twiv.tv.
Subscribe (free)
Click here to receive an email notification when a new episode of TWiP is published.
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TWiP #17 - Entamoeba histolytica
6 oktober 2010 · 1 uur 16 min
Vincent and Dickson continue their discussion of protozoan parasites that cause diarrhea with a review of amebic dysentery caused by Entamoeba histolytica. Lees meer
Host links: Vincent Racaniello and Dickson Despommier
Links for this episode:
Entamoeba histolytica cyst (jpg)
Entamoeba histolytica trophozoite (jpg)
Entamoeba histolytica life cycle (jpg)
Galactose prevents attachment of amoebae to cells (jpg)
Entamoeba histolytica life cycle (jpg)
Charcot-Leyden crystal (jpg)
Letters read on TWiP 17
Contact
Send your questions and comments (email or mp3 file) to twip@twiv.tv.
Subscribe (free)
Click here to receive an email notification when a new episode of TWiP is published.
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TWiP #16: Giardia
24 september 2010 · 1 uur 19 min
Vincent and Dickson review the life cycle and pathogenesis of the flagellated protozoan parasite Giardia lamblia. Lees meer
Host links: Vincent Racaniello and Dickson Despommier
Links for this episode:
Giardia lamblia trophozoite (jpg)
Giardia lamblia cyst (jpg)
Giardia lamblia life cycle (jpg)
Heather's view of T. canis life cycle (pdf)
Letters read on TWiP 16
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TWiP #15: Tryp the light fantastic
9 september 2010 · 1 uur 27 min
Vincent and Dickson discuss the life cycle and pathogenesis of the protozoan parasite Trypanosoma. Lees meer
Host links: Vincent Racaniello and Dickson Despommier
Links for this episode:
Metacyclic trypanomastigote (jpg)
Tsetse fly (jpg)
T. brucei life cycle (jpg)
T. brucei parasitemia (jpg)
Kissing bug nymph (jpg)
T. cruzi life cycle (jpg)
Letters read on TWiP 15
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TWiP #14 - Leishmania
12 augustus 2010 · 1 uur 25 min
Vincent and Dickson consider the life cycle and pathogenesis of the protozoan parasite Leishmania. Lees meer
Host links: Vincent Racaniello and Dickson Despommier
Links for this episode:
L. braziliensis life cycle (jpg)
L. donovani life cycle (jpg)
L. tropica life cycle (jpg)
L. major lesion (jpg)
Transgenic mosquito delivers Leishmania vaccine (thanks, Geoffrey)
Plasmodium falciparum accompanied human expansion out of Africa (thanks, Prasad)
Who speaks for the guinea worm? (thanks, Michael)
Letters read on TWiP 14
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TWiP #13 - Toxoplasmosis
15 juli 2010 · 1 uur 25 min
Vincent and Dickson continue their discussion of the obligate intracellular protozoan Toxoplasma gondii with a consideration of the clinical consequences of infection and pathogenesis. Lees meer
Host links: Vincent Racaniello and Dickson Despommier
Links for this episode:
Isopod fish parasites (thanks, Kevin!)
Farmscraper on Word Spy (thanks, Mitchell!)
Toxoplasma and personalities (thanks, Greg!)
Science podcast (July 2) on parasites and intelligence (transcript - thanks, Jim!)
Letters read on TWiP 13
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TWiP #12 - Toxoplasma gondii
18 juni 2010 · 1 uur 38 min
Vincent and Dickson introduce the obligate intracellular protozoan Toxoplasma gondii, one of the most successful parasites on earth. Lees meer
Host links: Vincent Racaniello and Dickson Despommier
Links for this episode:
Global clinical burden of malaria (PLoS Medicine)
T. gondii sporulated oocysts (jpg)
T. gondii tachyzoites in parasitophorous vacuole (jpg)
T. gondii life cycle (jpg)
Insect bioterrorism conference (thanks, Don!)
Parasite of the Day (thanks, Douglas!)
World Science Festival
Letters read on TWiP 12
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TWiP #11 - One times three million
2 juni 2010 · 1 uur 27 min
Vincent and Dickson continue their discussion of malaria, with emphasis on clinical aspects of the disease. Lees meer
Host links: Vincent Racaniello and Dickson Despommier
Links for this episode:
The quest for a malaria vaccine (Meet the Scientist 49)
Science issue on malaria and tuberculosis
Malaria pathogenesis (pdf)
Malaria pathogenesis (jpg)
Letters read on TWiP 11
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TWiP #10 - Plasmodium life cycle
20 mei 2010 · 1 uur 26 min
Vincent and Dickson trace the life cycle of Plasmodium in a mosquito and in a human host. Lees meer
Host links: Vincent Racaniello and Dickson Despommier
Links for this episode:
Mosquito cycle - sporogany (jpg)
Plasmodium falciparum cycle (jpg)
Plasmodium vivax cycle (jpg)
Plasmodium falciparum ring forms and gametocytes in blood (jpg)
Plasmodium stages (jpg)
Letters read on TWiP 10
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TWiP #9 - Mala aria
6 mei 2010 · 1 uur 22 min
Vincent and Dickson move on to protozoan parasites with a discussion of the early history of malaria. Lees meer
Host links: Vincent Racaniello and Dickson Despommier
Links for this episode:
Malaria history at CDC
Radio New Zealand show on hookworms (thanks James!)
Tapeworm brain infection serious health concern (thanks Jim!)
Pig farmers try to limit pork tapeworm spread (thanks Gopal!)
Bizarre tongue-eating fish parasite (thanks Arsen!)
Letters read on TWiP 9
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TWiP #8 - Frog legs and parasite tales
22 april 2010 · 1 uur 23 min
Dickson reads his story about sparganosis caused by the diphyllobothroid tapeworm Spirometra mansonoides. Lees meer
Host links: Vincent Racaniello and Dickson Despommier
Links for this episode:
Spirometra life cycle (jpg)
Dickson on vertical farming (CNN episode on YouTube, thanks Jesse!)
Laboratory identification of parasites (CDC, thanks Michael!)
Gold nanoparticles take out brain parasite (Cosmos Magazine, thanks Gary!)
Letters read on TWiP 8
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TWiP #7 - Tapeworms are fantastic!
9 april 2010 · 1 uur 37 min
Vincent and Dickson continue their discourse on tapeworms, covering the fish and dog varieties. Lees meer
Host links: Vincent Racaniello and Dickson Despommier
Links for this episode:
FAT the enemy that is shortening your life is BANISHED. How? With sanitized tapeworms. Easy to swallow! (jpg).
D. latum life cycle (jpg)
D. latum adult (jpg)
Diphyllobothrim proglottid (jpg)
Diphyllobothrim bothria (jpg)
Coracidium hatching from egg (jpg)
Dog tapeworm life cycle (jpg)
The Alien lifecycle (jpg)
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TWiP #6 - Tapeworms, the long and short of it
25 maart 2010 · 1 uur 41 min
Vincent and Dick talk about the anatomy and life cycle of beef and pork tapeworms, and why House was wrong about neurocysticercosis. Lees meer
Host links: Vincent Racaniello and Dickson Despommier
Links for this episode:
Taenia saginata life cycle (jpg)
Taenia saginata adult (jpg)
Taenia saginata scolex (jpg)
Taenia saginata gravid proglottid (jpg)
Taenia solium life cycle (jpg)
Taenia solium adult (jpg)
Taenia solium scolex (jpg)
Facial cancer in Tasmanian devils (thanks PhogDog!)
Science Picks
Dickson Peace through vaccine diplomacy by Peter Hotez
Vincent Parasite Rex by Carl Zimmer -
TWiP #5 - The nurse cell
4 maart 2010 · 1 uur 19 min
Vincent and Dick discuss the nurse cell, a unique structure formed in the host muscle by Trichinella species. Lees meer
Host links: Vincent Racaniello and Dickson Despommier
Links for this episode:
Infective muscle larva (jpg)
Schematic of a larva invading a muscle cell
Nurse cell formation (scroll down the page)
Dickson's gallery of Trichinella images
Electron micrographs of stichocytes
Weekly Science Picks
Dickson Every Living Thing by Rob Dunn
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TWiP #4 - Trichinella life cycle
30 januari 2010 · 1 uur 22 min
Vincent and Dick trace the life cycle of Trichinella spiralis in an infected host. Lees meer
Host links: Vincent Racaniello and Dickson Despommier
Links for this episode:
Trichinella life cycle (jpg)
Newborn larva entering muscle cell (jpg)
Adult T. spiralis in columnar epithelial cell (jpg)
Adult female T. spiralis (jpg)
Infective first stage T. spiralis larva in Nurse cell in muscle tissue (jpg)
Adult female T. spiralis with fully formed larvae in uterus (jpg)
Adult male T. spiralis with claspers on tail (jpg)
Clinical correlations in trichinosis (jpg)
Letters read on TWiP #4
Weekly Science Picks
Dickson David Scharf's pictures of microbial life
Vincent The Nobel Laureate Meetings at Lindau -
TWiP #3 - Trichinella spiralis
28 december 2009 · 1 uur 4 min
Vincent and Dick distinguish among intracellular and extracellular parasites, then discuss the history and general characteristics of Trichinella spiralis. Lees meer
Host links: Vincent Racaniello and Dickson Despommier
Links for this episode:
The History of Trichinella at Trichinella.org
Parasite genome databases at the European Bioinformatics Institute
List of parasite genome projects
Weekly Science Picks
Dickson The Doctor and the Devils
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TWiP #2 - General parasitism
1 december 2009 · 1 uur 5 min
Vincent and Dick classify parasites according to whether or not they are transmitted by a vector, then consider the implications of long-lived parasites. Lees meer
Host links: Vincent Racaniello and Dickson Despommier
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TWiP #1 - Introduction to parasitism
13 november 2009 · 57 min
Vincent and Dick provide an overview of parasites and parasitism. Lees meer
Host links: Vincent Racaniello and Dickson Despommier
Weekly Science Picks
Dick The Black Cloud by Fred Hoyle
Vincent Parasitic Diseases by Despommier et al.