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364 afleveringen, van nieuw naar oud

Ep. 63: “Reprogrammed Stomach” Featuring Dr. Joe Zhou

12 april 2016 · 1 uur 11 min
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Guest:
Stem cell researcher Dr. Joe Zhou from Harvard discusses his work and latest paper in Cell Stem Cell. His research covers beta cells, insulin regulation and organoids.
Ep. 62: “Forever Young” Featuring Dr. Aubrey de Grey

19 januari 2016 · 1 uur
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Guest:
We bring on writer and researcher Dr. Aubrey de Grey to discuss his work on anti-aging. We talk with Dr. de Grey on his latest findings and his ultimate goal of eliminating aging so we call can one day celebrate our 1000th birthday.
Resources and Links
Sex-Specific Mechanisms of Stress Susceptibility – According to this article, stress-related mental illnesses are twice as prevalent in women as in men.
Global Divergence of the Human Follicle Mite Demodex folliculorum: Persistent Associations between Host Ancestry and Mite Lineages – Researchers found that hosts with different regional ancestries harbor distinct lineages of mites and that these associations can persist despite generations spent in a new geographic region.
Pain Produces Memory Gain – This article reveals that physical pain can make memories last longer.
Integrated, Multi-Cohort Analysis Identifies Conserved Transcriptional Signatures across Multiple Respiratory Viruses – Researchers performed two integrated, multi-cohort analyses of publicly available transcriptional data of viral infections.
Human Parasites in the Roman World – This article presents the archeological evidence for parasites in the Roman era in order to demonstrate the species present at that time, and highlight the health consequences for people living under Roman rule.
Key Elements of Healthy Eating Patterns – This article provides guidelines and key recommendations for individuals to enhance eating and physical activity patterns.
9 Science-Backed Steps to Have the Best Sleep of Your Life – Tonight – This article shares nine simple, science-backed strategies you can do today that'll increase your odds of sleeping better tonight and waking up refreshed tomorrow.
StemCells (STEM) Names New CEO – StemCells Inc. announced that Dr. Ian Massey, its President and Chief Operating Officer, has been appointed by the Board of Directors to succeed Martin McGlynn as the company’s Chief Executive Officer.
A Protein Biomarker Confirms the P… Lees meer
Ep. 61: World Stem Cell Summit 2015

5 januari 2016 · 1 uur 25 min
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Guest:
We feature some of our conversations with attendees from the 2015 World Stem Cell Summit from Atlanta, GA.
Happy New Year!
Resources and Links
4 New Elements Are Added to the Periodic Table – This article reports that the elements with atomic numbers 113, 115, 117 and 118 will get permanent names soon, according to the International Union of Pure and Applied Chemistry, with two of the four elements now known as ununseptium and ununtrium.
New Type of Moon Rock Discovered by China's Yutu Lunar Rover – China's Yutu lunar rover made the discovery on a long-dead lava flow in the giant Mare Imbrium dark spot and found the volcanic rock known as basalt which has intermediate levels of titanium.
CMV Vaccine Created at City of Hope Is Found Safe, Effective in Patients Receiving Stem Cell Transplants – City of Hope researchers report that an innovative vaccine known as CMVPepVax, that boosts cellular immunity against cytomegalovirus, or CMV, is safe and effective in stem cell transplant recipients.
Melting Sea Ice Increases Arctic Precipitation, Complicates Climate Predictions – This article reports that the melting of sea ice will significantly increase Arctic precipitation, creating a climate feedback comparable to doubling global carbon dioxide, according to the findings of Dartmouth College-led study.
Eating Poorly and Depressed? Yale Team Finds Connection — And Maybe a Solution – Yale researchers report that effects of a high-fat diet overlap with those of chronic stress and could also be a contributing factor in depression as well as metabolic disorders, such as type 2 diabetes.
MERS Vaccine Protects Camels, Which Is Good for People – The vaccine, which was developed by German scientists, protects against the virus that causes Middle East respiratory syndrome (MERS) and has been shown to be effective in camels.
Asperger's and Autism Linked to Decreased Action of Neurotransmitter GABA: Study – A new study from Harvard and MIT links autism symptoms to reduced acti… Lees meer
Ep. 60: “Stemcentrx” Featuring Scott Dylla

22 december 2015 · 55 min
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Guest:
Scott Dylla, CSO and co-founder of Stemcentrx, a really cool new company that is using novel technology to target stem cells as a therapy for different cancers, joins us for the interview portion.
Happy Holidays and New Year!
Photo Reference: Courtesy of Scott Dylla Lees meer

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Ep. 59: “Clinical Grade” Featuring Dr. Tilo Kunath

8 december 2015 · 1 uur 3 min
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Guest:
Dr. Tilo Kunath discusses his work on characterizing clinical grade stem cells so they can be used for patient therapies. We talk to Tilo about his past and current work, including his latest paper published in Scientific Reports. Don't miss Tilo's funny story!
Resources and Links
Boeing Develops New Metal that Could Revolutionize Airplanes – Boeing reveals microlattice: a metal so thin that it can sit on the head of a dandelion.
Smoking High-Strength Cannabis May Damage Nerve Fibres in Brain – People who regularly smoked strong skunk-like cannabis revealed subtle differences in the white matter that connects the left and right hemispheres and carries signals from one side of the brain to the other.
A Breakdown Product of Aspirin Blocks Cell Death Associated with Alzheimer's, Parkinson's and Huntington's Diseases – A new study finds component of aspirin binds to an enzyme, called GAPDH, which is believed to play a major role in neurodegenerative diseases, including Alzheimer's, Parkinson's and Huntington's diseases.
Sleep Deprivation Affects Stem Cells, Reducing Transplant Efficiency – Researchers found that a sleep deficit of just four hours affects by as much as 50 percent the ability of stem cells of the blood and immune system to migrate to the proper spots in the bone marrow of recipient mice and churn out the cell types necessary to reconstitute a damaged immune system.
Genome-Wide RNA-Seq of Human Motor Neurons Implicates Selective ER Stress Activation in Spinal Muscular Atrophy – This article shows that selective activation of ER stress underlies motor neuron death in spinal muscular atrophy.
Genetically Engineered Salmon Approved for Consumption – The federal regulators approved a genetically engineered salmon as fit for consumption, making it the first genetically altered animal to be cleared for American supermarkets and dinner tables.
Microgravity Inhibits Regenerative and Differentiation Potential of Embryonic Stem Cells – A study performed on t… Lees meer
Ep. 58: “Heart Disease Modeling” Featuring Dr. Lior Gepstein

24 november 2015 · 1 uur 7 min
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Guest:
Clinician and researcher Dr. Lior Gepstein discusses his work on using stem cells to model heart disease. We talk to Dr. Gepstein about his past and current work, including his latest paper published in Stem Cell Reports. His research covers human-induced pluripotent stem cell-cardiomyocytes and calcium levels.
Resources and Links
Antibiotic Resistance: World on Cusp of 'Post-Antibiotic Era – The world is on the cusp of a "post-antibiotic era", scientists have warned after finding bacteria resistant to drugs used when all other treatments have failed.
MG, the Newest STD on the Block, Found in over 1% of the Population – This article reports that slightly more than 1 percent of 4,500 participants tested positive for a sexually transmitted disease (STD) known as Mycoplasma genitalium (MG).
Parasitic Worm 'Increases Women's Fertility' – This article suggests that infection with a species of parasitic round worm, Ascaris lumbricoides that alters the immune system, makes it easier for women to get pregnant.
How a Raisin Can Predict a Toddler's Future Academic Ability – A simple test using a raisin can predict how well a toddler will perform academically at age eight, based on a research conducted at the University of Warwick.
Uterus Transplant: First US Clinical Trial Begins – This article reports that the first clinical trial of uterus transplantation in the United States has begun at Cleveland Clinic in Ohio, and in the process of selecting women with uterine factor infertility, a condition in which a woman was born without a uterus, has lost her uterus, or has a uterus that no longer functions.
Viagra for Type 2 Diabetes: 'Little Blue Pill' Reduces Insulin Resistance without Risk of Heart and Kidney Disease – This article reveals that Sildenafil, active ingredient in Viagra, may improve insulin sensitivity and prevent type 2 diabetes, without heart and kidney disease risk.
'Ringo the Dog' Helps Find Potential New Therapy for Muscular Dystrophy – Ringo, a golde… Lees meer
Ep. 57: “Curiosity” Featuring Duane Fernandez

10 november 2015 · 1 uur 10 min
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Guest:
Writer, director and photographer Duane Fernandez talks about how curiosity drives him and his work. We talk to Duane on his experience with helping people from all walks of life and business experience their true potential and how this can apply to science.
Resources and Links
The Woman Who Can Smell Parkinson's Disease – According to this article, a woman from Perth named Joy Milne can detect people with Parkinson’s through a telltale odor.
Neurons from Glia In Vivo – Scientists present new recipes for directly converting glial cells to neurons in mouse brains.
Exclusive Video: First "Glowing" Sea Turtle Found – Scientists diving near the Solomon Islands made an illuminating discovery: the first biofluorescent reptile ever recorded.
Japanese Scientist Haruko Obokata Stripped of Doctorate over Stem Cell Scandal – Waseda University revoked a doctoral degree awarded to a young researcher embroiled in a scandal that has rocked the scientific establishment.
Fighting Citrus Greening with Vibrating Orange Groves – According to this article, hijacking the mating signals of Asian citrus psyllids may help provide an environmentally friendly system for preventing citrus greening - a disease that has cost the Florida citrus industry billions of dollars in recent years.
Neurons Reprogrammed in Animals – Harvard Stem Cell Institute researchers have now shown that the networks of communication among reprogrammed neurons and their neighbors can also be changed, or “rewired.”
A Cell Therapy Untested in Humans Saves a Baby with Cancer – This article reveals that cancer doctors have been electrified by a new approach that involves genetically altering patients’ T cells, the soldiers of the immune system, so that they can better attack cancers.
Ovarian Cancer Drug Promising for Prostate Tumors – Olaparib, a drug designed to fight inherited ovarian cancers in women, appeared to help some men with advanced prostate cancer done in a small trial.
Insulin Plays Very Strong Role in… Lees meer
Ep. 56: “Glia” Featuring Dr. Steven Goldman

27 oktober 2015 · 1 uur 14 min
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Guest:
Dr. Steven Goldman from the University of Rochester talks about glial cells and his work using neural stem cells to model and fix diseases, like multiple sclerosis.
Resources and Links
Can a Cancer Drug Reverse Parkinson's Disease and Dementia? – A drug that's already approved for treating leukemia appears to dramatically reduce symptoms in people who have Parkinson's disease with dementia, or a related condition called Lewy body dementia.
Study Shows Antioxidant Use May Promote Spread of Cancer – Scientists at the Children’s Research Institute at The University of Texas Southwestern have made a discovery that suggests cancer cells benefit more from antioxidants than normal cells, raising concerns about the use of dietary antioxidants by patients with cancer.
Sitting for Long Periods Is No Worse for Your Health than Standing, Study Claims – This article reveals that prolonged sitting doesn’t appear to be killing you any faster than standing.
Does Fungus Cause Alzheimer's? – In this article, researchers discover traces of fungus in the brains of Alzheimer's sufferers.
Schizophrenia Symptoms Linked to Features of Brain's Anatomy? – This article describes how Washington University psychiatrist C. Robert Cloninger, MD, PhD, and fellow researchers have matched certain behavioral symptoms of schizophrenia to features of the brain's anatomy using advanced brain imaging.
Can Diamonds Detect Cancer? – A new study out of Australia found that synthetic versions of diamonds to be effective at detecting early-stage cancerous tumors through magnetic resonance imaging.
Armed Malaria Protein Found to Kill Cancer Cells – A new type of cancer therapy based on seemingly unrelated elements of malaria and cancer is showing promise for development.
Ebola Found in the Semen of Some Men Nine Months Later – This article reveals that some men still have fragments of Ebola virus in their semen nine months after first showing symptoms of the virus.
Larger Brains Do Not Lead to High IQs… Lees meer
Ep. 55: Biomaterials and Stem Cells Featuring Dr. David Mooney

14 oktober 2015 · 1 uur 9 min
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Guest:
Dr. David Mooney, Professor of Bioengineering at the Harvard School of Engineering and Applied Sciences discusses his work using biomaterials to help stem cells more efficiently integrate after transplantation.
Resources and Links
Gene-Editing Record Smashed in Pigs – Researchers modify more than 60 genes using CRISPR/Cas9 gene-editing technology in effort to enable organ transplants into humans.
NASA Discovers Evidence for Liquid Water on Mars – NASA scientists have found compelling evidence that liquid water exists on Mars based on the “recurring slope lineae,” patches of precipitated salt that appear to dribble down Mars’ steep slopes like tears rolling gently down a cheek.
Stem Cell Fraud: A 60 Minutes Investigation – Scott Pelley confronts one disgraced doctor offering false hope to a family with a disabled child using unproven stem cell treatment.
Photo Reference: Courtesy of Dr. David Mooney Lees meer

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Ep. 54: Stem Cell Lineage Tracing Featuring Dr. Andrew Cohen

29 september 2015 · 1 uur 13 min
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Guest:
Dr. Andrew Cohen, Associate Professor at Drexel University, discusses his work on creating new software and programs to track stem cell lineages using time lapse video data.
Resources and Links
Antidepressants plus Blood-Thinners Slow Down Brain Cancer – Ecole Polytechnique Fédérale de Lausanne scientists found that combining antidepressants with anticoagulants slows down brain tumors in mice.
Seasonal Body Clocks Are Controlled By 'Calendar Cells': Scientists Identify Proteins that Determine When Mammals Mate – According to this article, experts found that “calendar cells” in a structure called the 'pars tuberalis' respond according to how much daylight there is and can change dramatically over the year, driving the seasonal reproductive cycle.
Wine's Darkest Secret Revealed - It's All in the Fungi – This article reveals that a type of yeast called Saccharomyces cerevisiae, makes a "small but significant" contribution to a wine's flavor and taste.
Edges of Human Embryonic Stem Cell Colonies Display Distinct Mechanical Properties and Differentiation Potential – This article describes the results found after the live imaging of the differentiation process of human embryonic stem cells, and reveals that cells on the outer edge of the undifferentiated colony begin to differentiate first and remain on the perimeter of the colony to eventually form a band of differentiation.
Orthostatic Hypotension May Indicate Neurological Disease – According to this article, orthostatic hypotension may be an early warning sign of a serious neurological disease and may be associated with an increased risk of premature death.
Why People in 'Tall' Nations Are More Likely to Be Slim – Researchers from Australia looked at nearly 9,500 people in 14 European countries and found a strong connection between genes that boost height and those associated with lower amounts of body fat.
Salsalate Drug Offers New Hope for Treating Alzheimer's Disease and FTD – Scientists from the Gladstone I… Lees meer
Ep. 53: Automated iPS Cells Featuring Dr. Scott Noggle

15 september 2015 · 1 uur 6 min
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Guest:
Dr. Scott Noggle, VP of Stem Cell Research at The New York Stem Cell Foundation discusses his automated system for making iPS cells. Dr. Noggle applies new advances in pluripotent stem cell biology and cell reprogramming to the creation of human models of neurodegenerative diseases, such as Alzheimer’s disease and Parkinson’s disease to discover new disease targets. Lees meer
Ep. 52: Stem Cells and Autism Featuring Dr. Flora Vaccarino

1 september 2015 · 1 uur 10 min
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Guest:
Dr. Flora Vaccarino from Yale University joins the show to discuss stem cells and autism, specifically her work on neural stem cells and how she is using them to study Autism Spectrum Disorder.
Ep. 51: Stem Cell Theranostics Featuring Dr. Chris Armstrong

18 augustus 2015 · 1 uur 4 min
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Guest:
Dr. Chris Armstrong, CEO of Stem Cell Theranostics, joins the hosts to discuss his company and how they are using iPSCs to model cardiovascular disease.
Resources and Links
Elusive Liver Stem Cell Identified in Mice by Researchers – Researchers at the Stanford University School of Medicine identified a cell type in the liver of mice that can both self-renew and make new liver cells.
Can Crime Scene Compound Stop Malaria? – Luminol, the glowing compound detectives spray at crime scenes to find trace amounts of blood, may one day be used to kill the malaria parasite.
Anti-Smoking Bacteria Found to Eat Nicotine – Scientists discovered anti-smoking bacteria called Pseudomas putida that eat nicotine before it reaches the brain.
How To Reach 'Extreme Old Age': Scientists Reveal the Secret of Living to 100 Years Old – There is a good chance centenarians and super-centenarians - those who live to 105 and longer - will pass on their 'long life' genes on to their children.
Non-Magnetic Metals Turned Magnetic in Groundbreaking Research – A team of scientists led by the University of Leeds has been able to turn the non-magnetic materials manganese and copper magnetic.
Study Offers First Genetic Analysis of People with Extremely High Intelligence – The first ever genetic analysis of people with extremely high intelligence has revealed small but important genetic differences between some of the brightest people in the United States and the general population.
3D Brain Map Reveals Connections Between Cells in Nano-Scale – Scientists have created an unprecedented high-resolution map of the brain that reveals structures as small as those found in individual nerve cells.
Stem Cells Help Researchers Determine Toxicity of Pollution – The effects of BPA on mouse stem cells could be detected and measured in lab tests by researchers.
MicroRNA-153 Regulates the Acquisition of Gliogenic Competence by Neural Stem Cells – This article shows that miR-mediated fine control of nuclear fa… Lees meer
Ep. 50: Global Perspective Featuring George Daley of the Harvard Stem Cell Institute

4 augustus 2015 · 1 uur 10 min
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Guest:
For this episode, we bring on internationally recognized stem cell pioneer Dr. George Daley from Children’s Hospital Boston and the Harvard Stem Cell Institute to discuss all things stem cells.
Resources and Links
New Ebola Vaccine Has ‘100 Percent’ Effectiveness in Early Results – Researchers announced promising results of a new vaccine’s trial called Ebola ça Suffit — French for “Ebola that’s enough” funded by World Health Organization, in Guinea, one of several countries affected by a historic outbreak in West Africa.
Synthetic Ribosome Can Keep Bacteria Alive – According to this article, scientists have engineered a tethered ribosome that works nearly as well as the real thing—an organelle that produces all the proteins and enzymes within the cell.
Anxiety and Depression Caused By Stress Linked to Gut Bacteria Living in Intestines, Scientists Find – Anxious and depressive behavior brought on by exposure to stress in early life appears only to be triggered if microbes are present in the gut.
Scientists Have Discovered the Taste of Fat and Say It Could Hold the Key to Tackling Obesity – Scientists describe the taste of fat as a unique and unpleasant taste called oleogustus, and suggest that its identification could lead to new ways of fighting obesity and heart disease, and to the creation of improved fat replacements.
Study Shows Glitazone Antidiabetic Drug May Reduce Risk of Parkinson’s Disease – Researchers found that diabetes patients taking glitazone antidiabetes drugs (either rosiglitazone or pioglitazone) had a 28% lower incidence of Parkinson’s disease than people taking other treatments for diabetes who had never taken glitazones.
Long-term Memories Are Maintained by Prion-like Proteins – Research from Eric Kandel’s lab at Columbia University Medical Center reveals that different prions are critical for the long-term storage of memories.
Astronomers Spot Black Hole So big, It Defies Current Theories of Galaxy Evolution – This article describes the… Lees meer
Ep. 49: SCP Sweden Part 2 – Live Interviews from the ISSCR Conference in Sweden 2015

21 juli 2015 · 2 uur 29 min
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Guest:
In this episode we give you the second part of our broadcast live from the ISSCR 2015 International Conference from Stockholm, Sweden. On the show, we randomly pull attendees aside and ask them to us their stem cell story, and detail some of their research topics and accomplishments. Some of those interviewed on the show include Dr. Sean Morrison, the President of ISSCR, and Dr. Paul Tesar of Case Western Reserve University. Lees meer

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Ep. 48: SCP Sweden Part 1 – Live Interviews from the ISSCR Conference in Sweden 2015

7 juli 2015 · 2 uur 30 min
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Guest:
In this episode we broadcast live from the ISSCR 2015 International Conference from Stockholm, Sweden. On the show, we randomly pull attendees aside and ask them to us their stem cell story, and detail some of their research topics and accomplishments. Everyone from graduate students, post-docs, patients who have received stem cell transplants, to big name researchers, we get them all. Lees meer

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Ep. 47: The Stem Cell Podcast Round Up Only

23 juni 2015 · 38 min
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Guest:
In this episode we discuss topics ranging from, more sports stars getting stem cell therapy, a mutation that eliminates prion disease, a perspective on aging by studying stem cells, chimps getting drunk in the wild on there own, a Nobel laureate who made awful comments regarding women in science and your birthdate as a predictor of disease.
Resources and Links
Scientists Film Death of White Blood Cell for First Time and Discover Alert System – Australian and US scientists capture on video each stage of death of a human white blood cell, revealing the dying cells apparently try to alert their neighbors by ejecting molecules into nearby cells, possibly to alert them to the potential presence of a pathogen.
Sun like It Hot: Philae Comet Probe Wakes up, Phones Home Again – European Space Agency has confirmed that the Philae probe on Comet 67P/Churyumov-Gerasimenko has been in contact again, and that the lander is getting more than enough sunshine on its solar panels to power itself continuously.
Molecules Reach Coldest Temperature Ever – This article describes how the MIT researchers chilled a gas of sodium potassium 500 nanokelvin.
New Study: Chimps Go Bananas over Palm Wine – Scientists report that chimps in western Africa have taken to purloining drinks from vats of palm wine left unguarded by humans.
Autism Risk May Be Influenced by Age Gap Between Parents – Researchers have demonstrated with the largest ever multinational study of parental age and autism risk that the children of teen mothers, older parents and parents with an age gap of ten years or more have a higher risk of autism spectrum disorder than other children.
Nobel Prize-winning Professor Tim Hunt Resigns after Sexist Remarks about 'Girls' in Lab – The Nobel Prize-winning biochemist Tim Hunt stepped down from his position at the University College London after making sexist comments at the World Conference of Science Journalists in South Korea.
Your Birth Month May Predict Your Health Issues: H… Lees meer
Ep. 46: “ISSCR Conference Preview” Featuring Dr. Heather Rooke

9 juni 2015 · 56 min
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Guest:
Heather Rooke, Science Director at ISSCR previews the 2015 ISSCR conference in Stockholm, Sweden.
Resources and Links
Sawfish Resort to Virgin Births to Dodge Extinction – Scientists have discovered that some of the smalltooth sawfish have resorted to "virgin births" or what is called facultative parthenogenesis in the wild in an effort to survive.
First Steps Taken for Regenerating Whole Limbs – The first steps toward developing "bioartificial" replacement limbs that are suitable for transplantation have reportedly been taken by a team at Massachusetts General Hospital in Boston.
Study Uncovers Link Between Blood Type and Risk of Cognitive Decline – This article reveals that blood type also may affect cognitive function as we age according to a study conducted by researchers at the University of Sheffield in England.
'Landmark Discovery' of Vessels Connecting Brain to Immune System – The University of Virginia claim that "decades of textbook teaching" have been overturned by their researchers, who have found a previously undiscovered connection between the brain and the immune system.
‘Female Viagra’ Won’t Help Many, but That’s Not Stopping the Drug Company – This article describes the transition of Flibanserin, a pill initially intended to be an anti-depressant, to be marketed as a ‘female viagra’ or a pill to increase women’s sexual desires.
Ubble: The Online Test to Predict If You'll Die Within Five Years – According to this article, if you are a middle-aged man and want to know if you are going to die in the next five years, you simply need to ask yourself how healthy you think you are based on the website called Ubble (for UK Longevity Explorer).
How an Undergraduate Discovered Tubes of Plasma in the Sky – This article describes the discovery of tubes of plasma drifting above Earth by an undergraduate student – Cleo Loi of Sydney Institute for Astronomy.
The Philosophy of the Large Hadron Collider – The Large Hadron Collider at the European Organizatio… Lees meer
Ep. 45: “Differentiation” Featuring Alex Hannay

26 mei 2015 · 47 min
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Guest:
Alex Hannay, product manager at Thermo Fisher talks about the process of differentiation from pluripotent stem cells and new products that could help.
Resources and Links
This Genetically Modified Yeast Can Now Brew Morphine – Biologists in California and Canada have created strains of yeast that can feast on sugar and make opiates – the key ingredients in pain relievers like morphine.
Juvenile Plasticity Returned to Adult Mice Brains – UC Irvine scientists have managed to make an old brain young again by transplanting a type of embryonic neuron into the brains of adult mice.
Why Do Men Still Exist? Scientists Finally Find the Answer – This article suggests that sexual competition for mates keeps populations healthy, free of disease and genetically diverse.
Discovery of Rare Quadruple Quasar System Baffles Astronomers – Astronomers have discovered four of the rare, super-luminous celestial objects known as quasars arrayed in close proximity to one another.
New Test Detects Drug Use from a Single Fingerprint – This article describes a new, non-invasive test presented by researchers that can detect cocaine use through a simple fingerprint.
Ocata Therapeutics Announces Positive Results in Treating Macular Degeneration Using Fully Differentiated Stem Cell-Derived Retinal Pigment Epithelium (RPE) Cells in Asian Patients – Ocata Therapeutics, Inc. announces a study that has been published that includes top-line, positive results in Asian patients who were treated with Ocata’s proprietary RPE cells, manufactured using its DeltaCell™ Technology.
First Database of Brain-cell Types Released by Allen Institute – Seattle’s Allen Institute for Brain Science has released the first database of brain cell types, along with new analysis to improve treatment of deadly brain cancer.
'Brain Wiring' May Influence Ability to Quit Smoking Successfully – Researchers from Duke Medicine in Durham, NC found that even with the help of nicotine replacement therapy and other smoking cess… Lees meer
Ep. 44: “Saratoga Stem Cell” Featuring Greg Smith, Christy Allen, Samantha Morris and Evangelos Kiskinis

12 mei 2015 · 1 uur 5 min
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Guest:
In this episode we discuss topics ranging from a chemical in vegetables that can destroy cancer stem cells, chewing gum to prevent signing a song over and over, the first report of germ line gene editing in human embryo, neuronal hyperactivity and neutral stem cells, and the discovery of a new pluripotent stem cell. The second half of the show comes live from The Next-Gen Stem Cell Conference in Saratoga NY, where we interview four scientists about their work and conference experience.
Resources and Links
Could High Blood Sugar Be a Cause of Alzheimer's Disease? – Scientists suspect one of the drivers that causes the complex brain changes that lead to Alzheimer’s disease is the accumulation of plaques of a faulty protein called beta-amyloid and that too much sugar in the blood can speed up the production of this protein.
Activin A Directs Striatal Projection Neuron Differentiation of Human Pluripotent Stem Cells – Activin A induces lateral ganglionic eminence (LGE) characteristics in nascent neural progenitors derived from human embryonic stem cells and induced pluripotent stem cells in a sonic hedgehog-independent manner.
Take a Deep Breath: Patients Find Relief through 3D Printing – A patient suffering from the rare condition, tracheobronchomalacia was treated with the use of 3D printing to construct a splint that would support the weakened trachea.
Relaxed DNA May Contribute to Aging – Analysis from scientists suggests that loosely wrapped DNA underlies the accelerated physical decline of Werner syndrome and promotes aging in the rest of the population.
U of M Institute Discovers How Aspirin Fights Cancer – Researchers discovered that aspirin might exert its chemopreventive activity against colorectal cancer, at least partially, by normalizing the expression of epidermal growth factor receptor in gastrointestinal precancerous lesions.
Bat-Winged Dinosaur Discovery Poses Flight Puzzle – This article describes the fossilized remains of a small, feathered di… Lees meer
Ep. 43: “A Closer Look At Stem Cells” Featuring Dr. Megan Munsie and Dr. Mario D’Cruz

28 april 2015 · 1 uur 10 min
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Guest:
Dr. Megan Munsie and Dr. Mario D'Cruz discuss the launch of ISSCR's new website "A Closer Look At Stem Cells" that aims to educate and empower people about stem cell biology and stem cell treatments.
Resources and Links
The Number One Cause of Depression — Everywhere – A group of researchers from around the world discovered that people who have suffered from abuse during their childhood are more likely to be diagnosed with clinical depression — and even more so if they are genetically predisposed to the condition.
Major Advance in Artificial Photosynthesis Poses Win/Win for the Environment – Artificial photosynthesis has been achieved with the development of a system that can capture carbon dioxide emissions before they are vented into the atmosphere and then, powered by solar energy, convert that carbon dioxide into valuable chemical products, including biodegradable plastics, pharmaceutical drugs and even liquid fuels.
Resistance to Antibiotics Found in Isolated Amazonian Tribe – Scientists discovered that Yanomami hunter-gatherers’ gut bacteria have already evolved a diverse array of antibiotic-resistance genes, even though these mountain people had never ingested antibiotics or animals raised with drugs.
Sarcasm Center Found in Brain's White Matter, Explaining Stroke Victims' Language Gap – Stroke victims often struggle to maintain language function, and regions governing sarcasm may get hit particularly hard.
Danish Researchers Develop New Blood Test Able to Predict Future Breast Cancer – Scientists at the University of Copenhagen developed a blood test method that can predict future breast cancer, which led to better prevention and early treatment of the disease.
Chimps Use Spears to Hunt – This article describes the capability of a troop of chimpanzees in southeastern Senegal to forge weapons to hunt, making them the only known group to use tools to injure or kill prey, and it turns out that females actually engage in this behavior more than males.
Wi… Lees meer
Ep. 42: “Neurogenesis” Featuring Dr. Fred Gage

14 april 2015 · 1 uur 5 min
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Guest:
Neuroscientist and stem cell pioneer Dr. Fred "Rusty" Gage, a professor at the Salk Institute where he discusses past, present, and future work of stem cells and neurogenesis.
Resources and Links
Too Much of a Bad Thing Can Be Good in Brain Tumors – DNA mutations can cause cancer but in some cases, more mutations may mean a better prognosis for patients like the one subtype of the most malignant brain tumor, called glioblastoma, or GBM.
Turbo-charging Hormone May Help Regrow the Heart, Animal Study Shows – Researchers at the Victor Chang Cardiac Research Institute discovered how to stimulate muscle regrowth in the heart of a mouse, which could be particularly important in looking at new treatments for those who suffer future heart attacks.
Aluminum Battery from Stanford Offers Safe Alternative to Conventional Batteries – Stanford University scientists have invented the first high-performance aluminum battery that's fast-charging, long-lasting and inexpensive that could replace many of the lithium-ion and alkaline batteries in wide use today.
Blackpoll Warblers Migrate Thousands of Miles across Atlantic Ocean, Scientists Find – A team of ornithologists led by William DeLuca of the University of Massachusetts, Amherst, reports the first direct evidence that the blackpoll warbler (Setophaga striata), relatively small songbirds, completes an autumn trans-Atlantic migration ranging from 2,270 to 2,770 km (1,410 to 1,721 miles) and requiring two to three days of non-stop flight.
Africa: Biodiversity Damage Mapped By Global Land-Use Study – Study concluded that, if human impacts continue to grow as they have been, future losses in biodiversity will be concentrated in biodiverse but economically poor countries.
Blown-Up Brains Reveal Nanoscale Details – A study showed that material used in diaper absorbant can make brain tissue bigger and enable ordinary microscopes to resolve features down to 60 nanometers; this technique is called expansion microscopy.
Repurposed … Lees meer
Ep. 41: “Chromosomal Disorders” Featuring Dr. Eirini Papapetrou

31 maart 2015 · 58 min
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Guest:
Dr. Eirini Papapetrou, an associate professor at the Icahn School of Medicine at Mt. Sinai where she discusses her work and latest paper on using stem cells to model blood diseases containing a chromosomal deletion.
Resources and Links
Sushi Parasite Inspires Worm Test for Cancer – Japanese researchers have discovered that Caenorhabditis elegans worms can detect cancer in people's urine.
New Genetic Variant that Causes Autism Identified by Johns Hopkins-Led Team – A Johns Hopkins-led team of researchers has identified a new genetic cause of the disorder using a novel approach that focuses on rare families severely affected by autism.
Bad Gene Cripples Flu Defenses – This article describes how a girl nearly died from flu because of mutated genes.
High-Fat Diet Alters Behavior and Produces Signs of Brain Inflammation – There is a great possibility that a high-fat diet produces changes in health and behavior, in part, by changing the mix of bacteria in the gut, also known as the gut microbiome.
NASA's Opportunity Rover Just Completed an 11-Year Marathon on Mars – NASA confirmed this week that the six-wheeled robot has now traveled more than 26.219 miles in eleven years and two months.
Apple's New ResearchKit: 'Ethics Quagmire' or Medical Research Aid? – Apple's ResearchKit is designed to let medical researchers create iPhone apps for their studies that will help them recruit participants — without said participants ever setting foot in the lab.
Woolly Mammoth DNA Inserted into Elephant Cells – This article describes the attempt of scientists to bring extinct species back from the grave through a process known as de-extinction.
Surprise Finding Heightens Concern over Tiny Bits of Plastic Polluting Our Oceans – A team of scientists’ accidental finding of plastic in the skin of both farmed and wild fish adds to already growing environmental and public health concerns about the plastic particles or microplastics pervading our oceans and waterways.
Altering Brain Ch… Lees meer
Ep. 40: “Gene Editing Mistakes” Featuring Dr. Frederick Alt

17 maart 2015 · 1 uur 4 min
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Guest:
Our guest, world-renowned geneticist, Dr. Fred Alt from Harvard Medical School talks about his latest paper in Nature Biotechnology where he describes a novel method to detect off target effects of gene editing technology.
Resources and Links
False Memories Implanted into the Brains of Sleeping Mice – By directly manipulating the brains of sleeping mice, researchers tricked the animals into thinking they had received a reward at a specific place when they wake up.
Autism Genes Linked to Higher Intelligence: Treading a Fine Line between Intellectual Disability and Superiority – A comprehensive study conducted shows that genetic variation, which increases risk for autism, is associated with better cognitive ability in non-autistic individuals.
Left or Right? The Brain Knows Before You Move – Scientists at Janelia Research Campus have identified a neural circuit that connects motor planning to movement.
Mutation May Cause Early Loss of Sperm Supply – Brown University biologists have determined how the loss of a gene in male mice results in the premature exhaustion of their fertility.
Sobering Effect of the Love Hormone – Oxytocin, sometimes referred to as the 'love' or 'cuddle' hormone, prevents alcohol from accessing specific sites in the brain that cause alcohol's intoxicating effects, sites known as delta-subunit GABA-A receptors.
Tapping into Beer's Therapeutic Potential – This article describes the study conducted by Chinese researchers on xanthohumol, a compound found in hops that prevented the brain cells from dying and also increased cell production of several antioxidants that counteracted oxidative damage.
Severe Depression Linked with Inflammation in the Brain – This article shows that there was a significant inflammation in the brains of the people with depression, and the inflammation was most severe among the participants with the most severe depression.
Ghrelin Hormone Supplement Increases Sex Drive – New studies have found that a supplement of g… Lees meer
Ep. 39: “Stressed Out Cells” Featuring Dr. Rhonda Newman

3 maart 2015 · 1 uur 10 min
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Guest:
Dr. Rhonda Newman to talk about her work in trying to figure out a better way to "de-stress" stem cells.
Resources and Links
Previously Unknown Effect of Vitamin A Identified – A previously unknown effect of vitamin A in human embryonic development has been identified by researchers, indicating that vitamin A affects the formation of blood cells.
Feeding Babies Foods with Peanuts Appears to Prevent Allergies – Researchers found that babies who consumed the equivalent of about 4 heaping teaspoons of peanut butter each week, starting when they were between 4 and 11 months old, were about 80 percent less likely to develop a peanut allergy by age 5.
Mothers Can Pass Traits to Offspring through Bacteria’s DNA – Mothers can pass a trait to their offspring through the DNA of bacteria suggesting that microbes may play a significant role in how genes influence illness and health in higher organisms.
Kids, Allergies and a Possible Downside to Squeaky Clean Dishes – This article reports that in families who said they mostly wash dishes by hand, significantly fewer children had eczema, and somewhat fewer had either asthma or hay fever, compared to kids from families who let machines wash their dishes.
Scientists Unveil Map of 'Epigenome,' a Second Genetic Code – Scientists for the first time have mapped out the molecular "switches" that can turn on or silence individual genes in the DNA in more than 100 types of human cells, an accomplishment that reveals the complexity of genetic information and the challenges of interpreting it.
Ingredient in Olive Oil Looks Promising in the Fight Against Cancer – A Rutgers nutritional scientist and two cancer biologists at New York City’s Hunter College have found that an ingredient in extra-virgin olive oil called oleocanthal kills a variety of human cancer cells without harming healthy cells.
Popular Soda Ingredient Poses Cancer Risk to Consumers – Research analysis suggests that soda drinkers consume one or more cans per day—possi… Lees meer
Ep. 38: Cell Transplant Therapy Featuring Dr. Lorenz Studer

17 februari 2015 · 1 uur 5 min
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Guest:
Dr. Lorenz Studer is the founding director of the Sloan-Kettering Center for Stem Cell Biology a Member in the Developmental Biology Program and the Department of Neurosurgery and Professor in Neuroscience at Weill-Cornell Graduate School.
Resources and Links
Novel "Smart" Insulin Automatically Adjusts Blood Sugar in Diabetic Mouse Model – Scientists have created Ins-PBA-F, a long-lasting "smart" insulin that self-activates when blood sugar soars, eliminating the need for additional boosts of insulin, and reducing the dangers that come with inaccurate dosing.
Scientists Find Mysterious Magnetism in Earth’s Inner Core – A team of U.S. and Chinese geophysicists suggests that the innermost core is rotated on its side compared to its outer layer and the team also provides new clues about how the inner core formed and began to solidify.
Test for HIV in Just 15 Minutes with This $34 Smartphone Dongle – A dongle created by Columbia University researchers can turn any smartphone (whether iPhones or Android devices) into an HIV and syphilis tester.
Research Team Identifies Link Between Inflammation and Type 2 Diabetes – This article describes how a Yale-led research team has identified the molecular mechanism by which insulin normally inhibits production of glucose by the liver and why this process stops working in patients with type 2 diabetes, leading to hyperglycemia.
Mutations Linked to Repair of Chromosome Ends May Make Emphysema More Likely in Smokers – This press release reveals that mutations in the telomerase reverse transcriptase gene that helps repair damaged chromosome ends may make smokers, especially female smokers more susceptible to emphysema.
Researchers Produce First Map of New York City Subway System Microbes – This article identifies the microbes present in the New York City subway system through a pathogen map or PathoMap and could be used for long-term, accurate disease surveillance, bioterrorism threat mitigation, and large scale health managem… Lees meer
Ep. 37: Repairing The Heart Featuring Dr. Christine Mummery

3 februari 2015 · 1 uur 11 min
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Guest:
Dr. Christine Mummery joins us to discuss how stem cells are being used for heart disease.
Resources and Links
CDC Reports Current Flu Vaccine Effectiveness at 23 Percent This Season – A report published estimates that getting a flu vaccine this season reduced a person’s risk of having to go to the doctor because of flu by 23 percent among people of all ages.
India's Tiger Population Sees 30 Percent Increase – According to this article, India says it now has almost a third more tigers than it did four years ago and it was willing to donate tiger cubs to the international community to help conservation efforts.
Scientists Give Genetically Modified Organisms a Safety Switch – Researchers at Harvard and Yale have used some extreme gene-manipulation tools to engineer safety features into designer organisms, specifically reprogrammed the common bacterium E. coli so it requires a synthetic amino acid to live.
WSU Researchers See Effect of BPA, Estradiol on Sperm Development – This article describes how bisphenol A and estradiol contributes to disrupted sperm production resulting in decreased sperm counts.
Too Much Salt Intake Changes Key Brain Circuits – This article shows that excessive salt intake "reprograms" the brain, interfering with a natural safety mechanism that normally prevents the body's arterial blood pressure from rising.
Trust Your Gut: E. Coli May Hold One of the Keys to Treating Parkinson's – Researchers recently discovered a protein in E. coli that inhibits the accumulation of potentially toxic amyloids—a hallmark of diseases such as Parkinson's.
Hidden Formaldehyde in E-Cigarette Aerosols – This article shows that the carcinogen formaldehyde, a known degradation product of propylene glycol that reacts with propylene glycol and glycerol during vaporization to produce hemiacetals, can be formed during the e-cigarette "vaping" process.
Laser-Generated Surface Structures Create Extremely Water-Repellent Metals – This article describes how scientists… Lees meer
Ep. 36: Disease Model Tools Featuring Dr. David Piper

19 januari 2015 · 1 uur 5 min
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Guest:
We talk to Dr. David Piper about disease model tools.
Resources and Links
Acute Immunomodulatory Effects of Binge Alcohol Ingestion – According to this article, alcohol can wreak havoc on your immune system from the moment you start imbibing.
BPA Alternative Disrupts Normal Brain-Cell Growth, Is Tied to Hyperactivity, Study Says – Researchers have shown why the chemical bisphenol-S once thought to be a safe alternative to bisphenol-A (BPA), which was abandoned by manufacturers of baby bottles and sippy cups after a public outcry, might itself be more harmful than BPA.
Extraordinary Gene Transfer between Cells Observed – A team of scientists observed that DNA from a mouse's second genome, or mitochondrial DNA, could be transferred from healthy tissue to tumor cells in mice, promoting cancer growth and spread.
Decline in Grants for Young Researchers Puts Future of Science at Risk, Johns Hopkins President Writes – In this article, the president of John Hopkins University Ronald J. Daniels urges policy reforms and increased National Institutes of Health funding for young scientists who most of them are already leaving the academic biomedical workforce posing a grave risks for the future of science.
A New Antibiotic Kills Pathogens Without Detectable Resistance – A group of researchers led by Prof Kim Lewis of Northeastern University in Boston, Massachusetts, has discovered a new antibiotic Teixobactin that eliminates Methicillin-resistant Staphylococcus aureus, Mycobacterium tuberculosis, Streptococcus pneumoniae, Bacillus anthracis and other dangerous pathogens without encountering any detectable resistance.
Drug Stimulates Brown Fat and Boosts Metabolism – This article describes how researchers figured out how FDA-approved drug mirabegron, typically used to treat overactive bladder, could boost brown fat’s metabolic burning efforts inside the body.
A Protein-Tagging System for Signal Amplification in Gene Expression and Fluorescence Imaging – Scientists develo… Lees meer
Ep. 35: CART Therapies Featuring Dr. Maria Themeli

6 januari 2015 · 1 uur 14 min
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Guest:
From the lab of Michel Sadelain, Dr. Maria Themeli talks to us about her work using stem cells to create killer T cells to seek and destroy cancer cells.
Resources and Links
Fat Isn't All Bad: Skin Adipocytes Help Protect Against Infections – Researchers report the surprising discovery that fat cells below the skin known as adipocytes help protect us from bacteria.
Researchers Target the Cell’s ‘Biological Clock’ in Promising New Therapy to Kill Cancer Cells, Shrink Tumor Growth – This article tells about the cell biologists at UT Southwestern Medical Center that have targeted telomeres with a small molecule called 6-thiodG that takes advantage of the cell’s "biological clock" to kill cancer cells and shrink tumor growth.
With Cancer, 'Bad Luck' of Random Mutations Is Largely to Blame – Scientists have created a statistical model that measures the proportion of cancer incidence, and have found that it's caused mainly by random mutations when stem cells divide.
Macrophages Contribute to the Cyclic Activation of Adult Hair Follicle Stem Cells – Skin resident macrophages surround and signal to resting hair follicle stem cells, regulate their entry into a new phase of hair follicle growth.
Meth Users Face Higher Risk for Parkinson's Disease – This article reveals that people who use methamphetamine have a greatly increased risk of developing Parkinson's disease and that women who took the drug had higher odds of the disease than men.
Molecular Mechanism Behind Health Benefits of Dietary Restriction Identified – Findings from researchers suggest that hydrogen sulfide is one of the key molecules responsible for the benefits of dietary restriction or calorie restriction such as slowing aging and extending lifespan.
Decoding Fat Cells: Discovery May Explain Why We Gain Weight – Researchers discovered that a protein, Thy1, has a fundamental role in controlling whether a primitive cell decides to become a fat cell, making Thy1 a possible therapeutic target for obesity… Lees meer
Ep. 34: 2014 Stem Cell Podcast Round Up

22 december 2014 · 47 min
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Guest:
On this episode it's just me and Yosif talking about a variety of hot papers with topics ranging from F-Class stem cells, wolves are better at math than dogs, the NFL is hating on stem cell transplants, STAP author can’t replicate findings, and there are actual sparks when sperm meets egg.
Resources and Links
New Type 2 Diabetes Treatment Cures Lab Animals of Disease – A new treatment for type 2 diabetes and obesity has been developed by researchers at Indiana University and the German Research Center for Environmental Health and has essentially cured lab animals of obesity, diabetes and associated lipid abnormalities through improved glucose sensitivity, and reduced appetite and enhanced calorie burning.
Laughing Gas Studied as Depression Treatment – This article reveals a study conducted by researchers on nitrous oxide, the laughing gas, as a potential treatment for severe depression in patients whose symptoms don’t respond to standard therapies.
Curcumin, Compound in Turmeric, Found to Impair Fear Memories and Ease PTSD Symptoms – Scientists have found that curcumin, the principal compound found in turmeric, can impair fear memories involved with the post-traumatic stress disorder (PTSD).
Rosetta Spacecraft Suggests Asteroids, Not Comets, Birthed Earth's Oceans – Asteroids, not comets, likely delivered Earth's ancient oceans from space based on the study from the Rosetta Spacecraft, which is now in orbit around a comet that is a frozen relic from the dawn of the planets.
Oldest Horned Dinosaur Species in North America Found in Montana: Hooked Beak, Sharply Pointed Cheeks Distinguishes Neoceratopsian Species – This article presents the naming of the first definite horned dinosaur species from the Early Cretaceous in North America specifically in Montana as Aquilops americanus, which exhibits definitive neoceratopsian features and is closely related to similar species in Asia.
Scientists Make 'Feel Full' Chemical – Based on this article, scientists have cre… Lees meer
Ep. 33: Skin Repair Featuring Dr. Marius Wernig

8 december 2014 · 1 uur 14 min
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Guest:
Dr. Marius Wernig from Stanford University talks about his work with stem cells and his latest paper published in Science Translation on using iPCs to treat a serious skin disorder.
Resources and Links
How Brain Scans Can Diagnose Autism With 97% Accuracy - A much more objective measure—reading a person’s thoughts through an fMRI brain scan—might be able to diagnose autism with close to perfect accuracy.
Mastodons Disappeared from Beringia before Ancient Humans Arrived – According to this article, new radiocarbon dates on American mastodon (Mammut americanum) fossils in Alaska and Yukon (eastern Beringia) suggest this species suffered local extinction tens of millennia before either human colonization.
HIV’s Slower Progression to AIDS Caused by Certain Gene-Protein and ARV – Infected people with a gene that expresses a particular human leukocyte antigens (HLA) protein called HLA-B*57 progress more slowly to AIDS than usual.
Radial Glia Require PDGFD–Pdgfrβ Signaling in Human but Not Mouse Neocortex – Researchers analyze differential gene co-expression relationships between the species, to demonstrate that the growth factor PDGFD is specifically expressed by Radial Glia in human, but not mouse, corticogenesis.
Vegetable Oil Ingredient Key to Destroying Gastric Disease Bacteria – A group of researchers developed LipoLLA, a therapeutic nanoparticle that contains linolenic acid, which is a component in vegetable oils, to dampen H. pylori bacteria and inflammation that lead to ulcers and gastric cancer in mice.
Scientists Uncover Gene Associated with an Aggressive Breast Cancer – Scientists have identified a biomarker, a gene called RASAL2 that is strongly associated with triple negative breast cancer (TNBC), a highly aggressive carcinoma that often has early relapse and metastasis following chemotherapy.
Star Trek-Like Invisible Shield Found Thousands of Miles Above Earth – Scientists have discovered an invisible shield roughly 7,200 miles above earth that block… Lees meer
Ep. 32: Parkinson’s Cell Therapy Featuring Dr. Malin Parmar

25 november 2014 · 1 uur 12 min
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Guest:
Dr. Malin Parmar to talk about her latest paper in Cell Stem Cell regarding Parkinson’s disease. This paper is very important and made main stream news everywhere.
Resources and Links
CERN’s Large Hadron Collider Adds Two New Subatomic Particles to the List – CERN's researchers have added two new subatomic particles that are six times as massive as protons.
Brain Structure Rediscovered – A Stanford graduate student Jason Yeatman has discovered what he thought was a new brain structure, known as the vertical occipital fasciculus, and later finds out that it was actually originally discovered in the late 19th century and got lost from the literature for more than 100 years.
‘Text Neck’ Is Becoming an ‘epidemic’ and Could Wreck Your Spine – This article warns us that hunching over your smartphone can cause back pain, posture problems.
Alcoholism Damages Brain's White Matter, Scans Show – Alcoholism damages white matter throughout the brain and this damage can be detected with brain scans according to the researchers.
A Man Lost in Musical Time – This article identifies the first documented beat deafness, a condition in which a person can't feel music's beat or move in time to it.
The Fault in Our Stars Might be a Virus – This article describes how the starfish on the western coast of North America started wasting away, a condition known as sea star wasting syndrome potentially caused by a new virus called sea star-associated densovirus or SSaDV.
Stupidity Virus' Lives In People's Throats, Crosses Over From Algae In Lakes – A virus commonly found in algae somehow made its way into people's throats, reducing their ability to perform certain tasks.
Genome-Wide Scan Demonstrates Significant Linkage for Male Sexual Orientation – Scientists have found even more evidence that sexual orientation is largely determined by genetics, not choice.
Why Killing Babies Makes Testicles Grow – Nearly half of mammal species surveyed in a new study practice infanticide and scientis… Lees meer
Ep. 31: Cell Stem Cell Editor featuring Dr. Christina Lilliehook

11 november 2014 · 1 uur 8 min
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Guest:
Senior editor at Cell Stem Cell, Dr. Christina Lilliehook shares with us what goes on as an editor of a top tier science journal. In addition to a behind the scenes discussion, she also talks about how she got into a career in editing, and what it takes if you wanted to make that career choice.
Resources and Links
Arachnophobia Gets Cut Out of Man’s Brain after Surgery to End His Seizures – This article discussed an instance where an unrelated seizure forced doctors to remove a portion of a man's brain, inadvertently freeing him of his fear of spiders.
Mystery Solved: Where the Penis Comes From – This article attempts to answer a question a lot of scientists ponder out loud that is key to much of life on Earth: Exactly how does the penis form?
Plasticity of the Aging Brain: New Directions in Cognitive Neuroscience – The authors review the two new directions in the field of aging research with implications for plasticity.
Modeling Ebola in Mice – This article is about a study conducted by a team of scientists who have tested 47 genetically diverse mouse lines in response to their susceptibility to Ebola.
Effects of Diurnal Variation of Gut Microbes and High-Fat Feeding on Host Circadian Clock Function and Metabolism – The body’s helpful bacteria may have internal clocks too that when disrupted will potentially boost the risk of obesity.
Dozens of Genes Associated with Autism in New Research – This press release discusses two new studies conducted by UC San Francisco scientists tying mutations in more than 100 genes to autism.
‘Treasure in Saliva’ May Reveal Deadly Diseases Early Enough to Treat Them, UCLA Scientists Report – A simple saliva test is capable of diagnosing early stage diabetes, cancer, and perhaps neurological disorders and autoimmune diseases.
Violence Genes May Be Responsible for One in Ten Serious Crimes – Scientists believe that they have discovered the genes responsible for high levels of rage-related violent behavior.
Jupiter-Sized Sunspot… Lees meer
Ep. 30: Nobel Conversation Featuring Dr. Harold Varmus

27 oktober 2014 · 58 min
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Guest:
In this episode we welcome Nobel Prize winning scientist, Dr. Harold Varmus. We talk with Dr. Varmus about a range of topics in the realm of biomedical research as a career and the state of NIH funding.
Resources and Links
Motor Skill Learning Requires Active Central Myelination – The production of new myelin in the brain, which is a function of non-neuronal glial cells, may be necessary for motor learning.
A Global Inventory of Lakes Based on High-resolution Satellite Imagery – Researchers were able to accurately count the lakes on earth with high resolution data from satellites.
UCL Research Helps Paralyzed Man to Recover Function – Researchers announced that two years after the cell transplant, a man paralyzed from chest down was able to walk again.
Soda and Cell Aging: Associations between Sugar-Sweetened Beverage Consumption and Leukocyte Telomere Length in Healthy Adults from the National Health and Nutrition Examination Surveys – Research found found that telomeres – protective DNA caps on the end of chromosomes – were shorter in people who reported habitually drinking more fizzy drinks.
Promising Early Success and Safety Results from International Gene Therapy Trial for 'Bubble Boy' Disease Reported in New England Journal of Medicine – This article describes a new form of gene therapy for boys with X-linked severe combined immunodeficiency syndrome (SCID-X1), a life-threatening condition also known as “bubble boy” disease.
Manipulating a “Cocaine Engram” in Mice – Researchers examine the precise neural circuits that support the memory of a cocaine-cue association or “cocaine engram” in mice.
Left–Right Dissociation of Hippocampal Memory Processes in Mice – This article shows that hippocampal long-term memory processing is lateralized in mice after investigating the implications of left-right difference in hippocampal function.
Histone H2A.Z Subunit Exchange Controls Consolidation of Recent and Remote Memory – According to this article, histone varian… Lees meer
Ep. 29: Brain Science Podcast Featuring Dr. Ginger Campbell

13 oktober 2014 · 1 uur 18 min
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Guest:
Dr. Ginger Campbell, host of the brain science podcast, joins the SCP where we discuss her podcast and different "brainy" topics. We close the show ranting about the iPhone 6.
Resources and Links
Near-Death Experiences? Results of the World's Largest Medical Study of the Human Mind and Consciousness at Time of Death
A Synthetic Stimulant Never Tested in Humans, 1,3-dimethylbutylamine (DMBA), Is Identified in Multiple Dietary Supplements
Tumors Might Grow Faster at Night
Sugar Linked to Memory Problems in Adolescent Rats
The Ancient Heritage of Water Ice in the Solar System
The 2014 Nobel Prizes At A Glance
Making Old Lungs Look Young Again
Judgment and Decision-making: Brain Activity Indicates There Is More than Meets the Eye
Peanut Allergy Misdiagnosed In 2 Out Of 3 Cases
Solving the Mystery of the “Man in the Moon”
Satellite Measurements Reveal Gravity Dip from Ice Loss in West Antarctica
Olfactory Dysfunction Predicts 5-Year Mortality in Older Adults
A Single Bout of Resistance Exercise Can Enhance Episodic Memory Performance
Sensitivity and Specificity of the Empirical Lymphocyte Genome Sensitivity (Lgs) Assay: Implications for Improving Cancer Diagnostics
Sleep Twitches Light up the Brain
Cells From Placentas Safe for Patients with Multiple Sclerosis
Research Shows Alcohol Sensations Influenced by Genes
Aromatic-Turmerone Induces Neural Stem Cell Proliferation In Vitro and In Vivo
Stem Cell Treatments Surging into Clinic
First Patient Treated in Neuralstem Phase I Spinal Cord Injury Stem Cell Trial through the UC San Diego Sanford Stem Cell Clinical Center
Japanese University May Strip Stem-Cell Scientist of Doctorate
Young, Brilliant and Underfunded
Studies Bring Tumeric to Stem Cell Research
Success in Creating Induced Pluripotent Stem Cells
Scientists Develop Barcoding Tools for Stem Cells
Giant Step toward New Diabetes Treatment
Generation of Functional Human Pancreatic β Cells In Vitro
Efficient Differentiation of Human Pluripotent Stem Cells to En… Lees meer
Ep. 28: New York Times and Stem Cells Featuring Karen Weintraub

29 september 2014 · 1 uur 10 min
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Guest:
We bring on freelance science writer Karen Weintraub to discuss her recent piece in the New York Times on stem cells. We talk with her about the contents of her article and what she learned doing the research. We then close the show with a rant on automatic car window openers.
Resources and Links
Comparing Low-Fat and Low-Carbohydrate Diets
An Engineered Axl 'Decoy Receptor' Effectively Silences the Gas6-Axl Signaling Axis
Tipping the Balance of Behavior
New Hadrosaur Noses into Spotlight
New Branch Added to European Family Tree
Pupil-Linked Arousal Determines Variability in Perceptual Decision Making
Human Faces Are so Variable Because We Evolved to Look Unique
TLR5-Mediated Sensing of Gut Microbiota Is Necessary for Antibody Responses to Seasonal Influenza Vaccination
Monster Black Hole Found in Tiny Galaxy
Gene Described as Critical to Stem Cell Development
Observation of a Dissipation-Induced Classical to Quantum Transition
Earth's New Address: 'Solar System, Milky Way, Laniakea'
Neuroscientists Identify Key Role of Language Gene
Schizophrenia Not a Single Disease but Multiple Genetically Distinct Disorders
Beyond the G-spot: Clitourethrovaginal Complex Anatomy in Female Orgasm
An Early Cretaceous Pterosaur with an Unusual Mandibular Crest from China and a Potential Novel Feeding Strategy
You Can Classify Words in Your Sleep
Researchers Find Neural Compensation in People with Alzheimer’s-Related Protein
Antibiotics Found in Human Body Bacteria
Study Links Honesty to Prefrontal Region of the Brain
A Phase I Study of the First-in-Class Anti-Mitochondrial Metabolism Agent, CPI-613, in Patients with Advanced Hematologic Malignancies
NUS Study Shows Effectiveness of Artesunate, a Common Herbal-Based Anti-Malarial Drug, in Controlling Asthma
Artificial Sweeteners Induce Glucose Intolerance by Altering the Gut Microbiota
STAP Co-Author Offers yet Another Recipe for Stem Cells
Stem Cell Tourism and Patient Education
Professional Regulation: A Potentially Valu… Lees meer
Ep. 27: MS and Stem Cells Featuring Dr. Valentina Fossati

16 september 2014 · 1 uur 12 min
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Guest:
Dr. Valentina Fossati from the New York Stem Cell Foundation, talks about her recent publication using iPSCs to generate the oligodendrocytes, the cells that myelinate neurons and its implications for multiple sclerosis.
Resources and Links
Vaccines—Calling the Shots
Study Finds Blood Type and Memory Loss Link
Textbook Theory Behind Volcanoes May Be Wrong
UV Light Can Turn Gene Into Source of Skin Cancers, Researchers Find
UCLA Biologists Delay The Aging Process By ‘Remote Control’
Eating Habits, Body Fat Related To Differences In Brain Chemistry
Can Sleep Loss Affect Your Brain Size?
First Neanderthal Rock Engraving Found in Gibraltar
Composition of Earth’s mantle revisited thanks to research at Argonne’s Advanced Photon Source
Marijuana Compound May Offer Treatment For Alzheimer’s Disease, USF Preclinical Study Finds
Neuroscientists Reverse Memories’ Emotional Associations
Scripps Research Institute Scientists Link Alcohol-Dependence Gene to Neurotransmitter
Estrogens Stimulate Serotonin Neurons to Inhibit Binge-Like Eating In Mice
Physically Fit Kids Have Beefier Brain White Matter Than Their Less-Fit Peers
Sexually Dimorphic RB Inactivation Underlies Mesenchymal Glioblastoma Prevalence in Males
FDA-Approved Drug Restores Hair in Patients with Alopecia Areata
Obituary: Yoshiki Sasai 1962–2014
Nature Reviewers Not Persuaded by Initial STAP Stem Cell Papers
Japanese Woman Is First Recipient of Next-Generation Stem Cells
Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human
Diabetes Researchers Find Faster Way to Create Insulin-Producing Cells
Stem Cells Help Researchers Understand How Schizophrenic Brains Function
The Developmental Potential of iPSCs Is Greatly Influenced by Reprogramming Factor Selection
Conversion of Human Fibroblasts into Monocyte-Like Progenitor Cells
Adult Hepatocytes Are Generated by Self-Duplication Rather than Stem Cell Differentiation
Chemical Conversion of Human Fibroblasts into Functional Schw… Lees meer
Ep. 26: Pluripotency Network Featuring Dr. Austin Smith

2 september 2014 · 1 uur 11 min
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Guest:
Dr. Austin Smith from Cambridge UK is on the show to discuss his take on the world of all things pluripotency. We talk about his views on the ground state of pluripotency and how he attempted to drill down into the essential components of the pluripotency network using computer modeling.
Resources and Links
Gut Bacteria That Protect against Food Allergies Identified
A Long Childhood Feeds the Hungry Human Brain
First Intact Organ Built from Cells
Clear Solar Panel Could Turn Smartphones and Tablets into Mini Power Plants, Michigan Researchers Say
Methane Is Bubbling Up From Hundreds of Places Along the U.S. East Coast Seafloor
Plant Development. Arabidopsis NAC45/86 Direct Sieve Element Morphogenesis Culminating in Enucleation.
Ohio Catholic Diocese Discourages ALS Ice Bucket Challenge
Children with Autism Have Extra Synapses in Brain
Transcriptomic Analysis of Tail Regeneration in the Lizard Anolis carolinensis Reveals Activation of Conserved Vertebrate Developmental and Repair Mechanisms
Traces of One of Universe's First Stars Detected
Cold, Dark and Alive! Life Discovered in Buried Antarctic Lake
This Could Explain Why Older Adults Can’t Stay Asleep
Biological Pacemaker Created By Minimally Invasive Somatic Reprogramming in Pigs with Complete Heart Block
Injected Bacteria Shrink Tumors in Rats, Dogs and Humans
Catholic Church Warns Pro-Lifers About Ice Bucket Challenge Donations
In Japan, Official Effort to Replicate STAP Stem Cells Comes Up Empty
Canadian Doctors Use Stem Cells to Treat 'Stiff Person Syndrome' Lees meer

Stem Cell Trial for Spinal Cord Injuries Cleared By FDA
Rogue Stem Cell Therapy Operators Charging Thousands For Ineffective Treatments, Researchers Say
Boron Facilitates Stem Cell Growth and Development in Corn
Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency
Generation of Multipotent Induced Neural Crest by Direct Reprogramming of Human Postnatal Fibroblasts with a Single Transcription Fac…
Ep. 25: STAP Recap Featuring Dr. Paul Knoepfler

19 augustus 2014 · 1 uur 20 min
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Guest:
Dr. Paul Knoepfler joins us to recap the STAP cell story in the light of the tragic death of Dr. Yoshiki Sasai. We also discuss a wide variety of topics related to publishing in science.
Resources and Links
Thousand-Strong Robot Swarm Throws Shapes, Slowly
SAGE Publications Busts “Peer Review And Citation Ring,” 60 Papers Retracted
Could a Dissolvable, Drug-Loaded Tampon Protect against HIV?
Why Living in the Moment Is Impossible
Our Brains Judge a Face’s Trustworthiness – Even When We Can’t See It
Growing Human GI Cells May Lead to Personalized Treatments
The Alzheimer's Cure That Worked on Mice
Clues To Curbing Obesity Found in Neuronal ‘Sweet Spot’
Breast Cancer's BRCA1 and BRCA2 Not the Only Gene Mutations to Worry About: Who Should Care about PALB2
Stanford Scientists Create Remote-Controlled Nanoscale Protein Motors
Stanford Bioengineering Team Builds Molecular Motors
Pepper and Halt: Spicy Chemical May Inhibit Gut Tumors
Study of Twins Discovers Gene Mutation Linked to Short Sleep Duration
Deletion of the Mitochondrial Chaperone TRAP-1 Uncovers Global Reprogramming of Metabolic Networks
Otzi Iceman Had Genetic Predisposition for Atherosclerosis: Much the Same in Ancient Peoples as It Is Today
Potential 'Universal' Blood Test For Cancer Discovered
Japanese Researcher, an Author of a Discredited Stem Cell Study, Is Dead
Brigham Researcher in Flawed Stem Cell Study Will Step Down
Transparency Promised for Vilified Impact Factor
A Stem Cell Study Shows Promising Results for Severe Stroke Patients
Stem Cell Research Gets Huge Boost from Australian Zebrafish Discovery
Stem Cells Reveal How Illness-Linked Genetic Variation Affects Neurons
A Simple And Efficient Method for Transfecting Mouse Embryonic Stem Cells Using Polyethylenimine
Seamless Gene Correction of Beta-Thalassemia Mutations in Patient-Specific Cells
Effect of Human Donor Cell Source on Differentiation and Function of Cardiac Induced Pluripotent Stem Cells
Generation of Rat-Induced Pluripotent S… Lees meer
Ep. 24: Sperm Stem Cells Featuring Dr. Marco Seandel

4 augustus 2014 · 1 uur 7 min
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Guest:
Dr. Marco Seandel from Weill Cornell Medical College joins the hosts to talk about his latest paper published in Stem Cell Reports, where he used sperm stem cells to uncover novel info about mutations in aged male sperm.
Resources and Links
Learning The Smell Of Fear: Mothers Teach Babies Their Own Fears Via Odor, Animal Study Shows
The Habenula Encodes Negative Motivational Value Associated with Primary Punishment in Humans
A Highly Abundant Bacteriophage Discovered in the Unknown Sequences of Human Faecal Metagenomes
Mysterious X-rays Might Hint at Dark Matter
Researchers Find First Sign that Tyrannosaurs Hunted in Packs
The Black Death in China
Longitudinal Changes in Total Brain Volume in Schizophrenia: Relation to Symptom Severity, Cognition and Antipsychotic Medication
Junk Food Could Destroy Your Sense of SMELL, Scientists Warn
Mechanisms of CFTR Functional Variants That Impair Regulated Bicarbonate Permeation and Increase Risk for Pancreatitis but Not for Cystic Fibrosis
Genetic Cause of Common Breast Tumors Found
Lawsuit Claims Stem Cells Unsafe Lees meer

California's Stem Cell Scandal Gets Worse

Sugar Mimic Helps Embryonic Stem Cells Develop Toward Nerve Cells

Teeth Sprout from Glia-Derived Stem Cells

Stem Cell Research Could Lead to New Muscle Repair Treatments
Stem Cell Therapy Could Lead to HIV Cure

Functional and Molecular Defects of Hipsc-Derived Neurons from Patients with ATM Deficiency

Spider Silk for Xeno-Free Long-Term Self-Renewal and Differentiation of Human Pluripotent Stem Cells

Role of Astroglia in Down's Syndrome Revealed by Patient-Derived Human-Induced Pluripotent Stem Cells

Generation Of Induced Pluripotent Stem Cells From Virus Freein Vivo Reprogramming of BALB/C Mouse Liver Cells

Gene Expression Variability as a Unifying Element of the Pluripotency Network

Enhanced Fitness of Adult Spermatogonial Stem Cells Bearing a Paternal Age-Associated FGFR2 Mutation

Photo Reference: Courtesy of Dr. Marco Seandel

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Ep. 23: Vascular Niche Featuring Dr. Daylon James

21 juli 2014 · 1 uur 1 min
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Guest:
Dr. Daylon James is back on the show to talk about a new paper in Nature where scientists used a vascular niche to help instruct and reprogram endothelial cells to blood stem cells.
Resources and Links
WHO: Ebola Outbreak Deaths in West Africa hit 603
Friends Are the Family You Choose: Genome-Wide Analysis Reveals Genetic Similarities among Friends
Oldest Case of Down Syndrome Discovered in 1,500-Year-Old Skeleton
Cracking the Code of How the Brain Processes Emotions
What Causes Autism? Rare Mutation in the CHD8 Gene May Be Responsible for Autism Subtype
New Alzheimer’s Test May Help Future Clinical Trials
Coffee Reduces the Risk of Parkinson's Disease
‘Asian Flush’ Signals Drinkers to Ease Up on Alcohol
Pelagornis sandersi: Paleontologist Discovers Largest-Ever Flying Bird
EU Court Adviser Backs Stem Cell Patenting
Large Study of Stem Cells for Autism Draws Criticism
Experimental Stem Cell Treatment Causes Woman To Grow Parts Of A Nose On Her Spine
Ground-Breaking Stem Cell Technique Developed To Heal Fractures And Prevent Amputations
Gene Profiling Technique to Accelerate Stem Cell Therapies for Eye Diseases
A Method To Recapitulate Early Embryonic Spatial Patterning in Human Embryonic Stem Cells
Biological Pacemaker Created by Minimally Invasive Somatic Reprogramming in Pigs with Complete Heart Block
Direct Induction of Haematoendothelial Programs in Human Pluripotent Stem Cells by Transcriptional Regulators
Reprogramming Human Endothelial Cells to Haematopoietic Cells Requires Vascular Induction
Photo Reference: Courtesy of Dr. Daylon James Lees meer

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Ep. 22: Novel Enhancers Featuring Dr. Paul Tesar

8 juli 2014 · 1 uur 15 min
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Guest:
This episode presents Dr. Paul Tesar from Case Western Reserve University. Dr Tesar talks about his paper in Cell Stem Cell.
Resources and Links
Bone Marrow Transplant Could Reverse Sickle Cell In Adults
Freezing Testicle Tissue in Mice Offers Fertility Hope for Cancer Survivors
Alzheimer's Linked to Brain Hyperactivity
Obesity Linked To Type 2 Diabetes by an Absent Protein
New Diabetes Drug Could Retrain GI Cells To Produce Insulin By Switching Off One Gene
Not All Stem Cells Created Equal
STAP Retracted
Supermassive Black Hole Obscures Heart of Galaxy with 'Rare and Powerful Stream of Gas'
Virus Kills Triple Negative Breast Cancer Cells, Tumor Cells in Mice
Torsina Hypofunction Causes Abnormal Twisting Movements and Sensorimotor Circuit Neurodegeneration
Destroying Bacterial Cell Walls May End Antibiotic Resistance Forever
If Blocked Endocannabinoids Trigger Dementia Symptoms, Could Cannabis Prevent Alzheimer’s?
Minimal Toolkit for Stem Cell Self-Renewal
Dinosaurs Were Mesothermic Beasts, Neither Warm-Blooded Nor Cold-Blooded
Geron hESC Trial to Resume?
Stem Cells Form Light-Sensitive 3-D Retinal Tissue Lees meer

Delivering Capsules of Stem Cells Helps Repair Injured Bones

Study Identifies Link Between Gut Bacteria Post SCT Survival

Stem Cells Slow Retinal Degeneration in Dry AMD Clinical Trial

Sustained ERK Activation Underlies Reprogramming in Regeneration-Competent Salamander Cells and Distinguishes Them from Their Mammalian Counterparts

Human ESC-Derived MSCs Outperform Bone Marrow MSCs in the Treatment of an EAE Model of Multiple Sclerosis

An iCRISPR Platform for Rapid, Multiplexable, and Inducible Genome Editing in Human Pluripotent Stem Cells

Epigenomic Comparison Reveals Activation of “Seed” Enhancers during Transition from Naive to Primed Pluripotency

Photo Reference: Courtesy of Dr. Paul Tesar

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EP. 21 The International Society for Stem Cell Research (ISSCR) Conference 2014

25 juni 2014 · 1 uur 16 min
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Guest:
This is a special episode consisting of over 75 minutes of live interviews. Last week The Stem Cell Podcast attended the International Society for Stem Cell Research meeting and pulled people aside to get their take on the meeting and stem cell research. We compiled all the interviews into one show for you to enjoy. Lees meer

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Ep. 20: SCNT Featuring Dr. Dieter Egli

9 juni 2014 · 1 uur 17 min
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Guest:
Dr. Dieter Egli from the New York Stem Cell Foundation joins the hosts to talk about his work in using SCNT to derive new embryonic stem cell lines. They discuss his previous and current work, including his latest story published in Nature.
Resources and Links
Sensing of Amino Acids in a Dopaminergic Circuitry Promotes Rejection of an Incomplete Diet in Drosophila
Histone Modifications Are Associated with Delta(9)-Tetrahydrocannabinol-Mediated Alterations in Antigen-Specific T Cell Responses
Compound in Saliva Helps Protect Our Cells from Toxins in Coffee, Tea, Study Shows
A Molecular Basis for Classic Blond Hair Color in Europeans
Engineering a Memory with LTD and LTP
Green Tea Component Upsets Cancer Cell Metabolism
Photoactivation of Endogenous Latent Transforming Growth Factor–β1 Directs Dental Stem Cell Differentiation for Regeneration
Targeting CXCL12 From FAP-Expressing Carcinoma-Associated Fibroblasts Synergizes with Anti–PD-L1 Immunotherapy in Pancreatic Cancer
Fighting Back: Patient's Own Immune Cells Tackle Cervical Cancer
A Draft Map of the Human Proteome
Abnormal Neuronal Differentiation and Mitochondrial Dysfunction in Hair Follicle-Derived Induced Pluripotent Stem Cells of Schizophrenia Patients
Role of the Primate Ventral Tegmental Area in Reinforcement and Motivation
Tai Chi Intervention Increases Progenitor CD34+ Cells in Young Adults
Unconditional Quantum Teleportation between Distant Solid-State Quantum Bits
Remission of Disseminated Cancer after Systemic Oncolytic Virotherapy
Less Pain (Receptors) Means a Longer Life
Mice with Mohawks Reveal Two Biological Pathways Linked with Autism Behaviors
CC Sabathia Ready to Throw for First Time since Stem-Cell Treatment for Knee
New Record Highs In Moral Acceptability - Premarital Sex, Embryonic Stem Cell Research, Euthanasia Growing in Acceptance
The Broad Foundation Advances Stem Cell Research at USC
Obokata Agrees to STAP Experiment
Inside a Corrupt Stem Cell Research Lab
EU Commission Rejects … Lees meer
Ep. 19: Saratoga Stem Cell Conference Review and 5 Interviews

26 mei 2014 · 1 uur 4 min
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The Stem Cell Podcast HostsDr. Fasano and Dr. Ganat
On this episode we review the Next Gen Stem Cell Conference from earlier in the month. During the conference we interviewed 5 stem cell scientists live and put them all together for this show. In addition to these great guests, we review the literature as always. Topics include the biggest sperm ever, C-kit+ stem cells don't make heart, heart on a chip technology, a new element on the periodic table, and iPSCs from schizophrenia patients. After that, we end with a rant about bathroom air fresheners! Lees meer

Resources, Links and Research Papers Mentioned In This Session Include:
World's Oldest Sperm Discovered: 17-Million-Year-Old Cell Is Longer Than Its Creator
Researchers Identify Link Between Colon Cancer And Metabolism
In Vivo Modulation Of Hypoxia-Inducible Signaling By Topographical Helix Mimetics.
Heart Cells Have 'Preteen' Growth Spurt
An Antidepressant Decreases CSF Aβ Production in Healthy Individuals and in Transgenic AD Mice
New Super-Heavy Element 117 Confirmed By Scientists
Autism-Related Protein Shown to Play Vital Role in Addiction
Chd5 Orchestrates Chromatin Remodelling During Sperm Development
‘Heart Disease-On-A-Chip’
Syphilis Made A Big Comeback In 2013, CDC Warns
Life Extension Factor Klotho Enhances Cognition
Meet HD 162826, The Sister Star Of Our Sun
Novel Antioxidant Makes Old Arteries Seem Young Again, Study Shows
Scripps Research Institute Scientists Create First Living Organism that Transmits Added Letters in DNA 'Alphabet'
Model Universe Recreates Evolution Of The Cosmos
Long-Snouted Tyrannosaur Unearthed
Vampire's Delight? Young Blood Recharges Brains of Old
Fate of iPSCs Derived from Azoospermic and Fertile Men following Xenotransplantation to Murine Seminiferous Tubules
Hope For Aging Brains, Skeletal Muscle
Stem Cell Therapy Saves Eyesight Of Fountain Valley Mother
c-kit+ Cells Minimally Contribute Cardiomyocytes To The Heart
Study Questions Use Of Stem Cells To Repair Heart
Modeling The Mi…
Ep. 18: Lou Gehrig’s Update Featuring Dr. Kevin Eggan

13 mei 2014 · 1 uur 13 min
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Guest:
Dr. Kevin Eggan from Harvard University joins the show to talk about his latest work using stem cells to cure ALS/Lou Gehrig’s disease.
Resources and Links
Fate of iPSCs Derived from Azoospermic and Fertile Men following Xenotransplantation to Murine Seminiferous Tubules
Hope for Aging Brains, Skeletal Muscle
Pain Curbs Sex Drive in Female Mice, but Not in Males
New Virus Related To Smallpox Is Found in Republic Of Georgia
Male Researchers Stress Out Rodents
Scripps Florida Scientists Find Connection Between Gene Mutation, Key Symptoms of Autism
Soy-Dairy Protein Blend and Whey Protein Ingestion After Resistance Exercise Increases Amino Acid Transport and Transporter Expression in Human Skeletal Muscle
Push Comes to Shove: Gilead's $1,000 Pill Could Hurt Insurer Earnings
Death Rates From Pancreatic Cancer Predicted to Rise in Europe in 2014
Human CLP1 Mutations Alter tRNA Biogenesis, Affecting Both Peripheral and Central Nervous System Function
Y chromosome is Not Disappearing, Researchers Say
Loss Of Memory Reversed in Alzheimer's Mice Models
MRSA Spreads in Households
REDD1 is Essential for Stress-Induced Synaptic Loss and Depressive Behavior
Amyloid Precursor Protein Regulates Neurogenesis by Antagonizing Mir-574-5p in the Developing Cerebral Cortex
Japanese Nobel Winner Latest to Apologize Over Stem-Cell Research
RIKEN to Check 20,000 Papers for Doctored Images and Plagiarism Lees meer

Stem Cells and the "Staircase of Shame"

Stem Cells May Be Key to Long Life: Research on Body of 115-Year-Old Woman

How Silly Putty May Advance Stem Cell Research
First Stem Cells Cloned From Diabetes Patient, Thanks to Egg Donors

Human Oocytes Reprogram Adult Somatic Nuclei of a Type 1 Diabetic to Diploid Pluripotent Stem Cells

Human Embryonic-Stem-Cell-Derived Cardiomyocytes Regenerate Non-Human Primate Hearts
Infertility: Stem Cell-Based Sperm Created From Infertile Mens Skin
Reprogramming Committed Murine Blood Cells to Induced Hematopoietic Stem Cells with Defined Factors
A…
Ep. 17: Naked Stem Cells Featuring Dr. Chris Smith of The Naked Scientists

22 april 2014 · 1 uur 18 min
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Guest:
In this episode we talk with the creator and host of The Naked Scientists; a website and podcast dedicated to all things science. We talk with Chris about his shows, and get his take on the stem cell field.
Resources and Links
House Windows That Double As Solar Panels? Shiny Quantum Dots Brighten Future of Solar Cells
Is Parkinson's an Autoimmune Disease?
KOI-3278: A Self-Lensing Binary Star System
Scientists Spot a Planet That Looks Like 'Earth's Cousin'
Female ‘Penis’ Found on Brazilian Cave Insects
Oh Baby: Scientists Find Protein That Lets Egg and Sperm Hook Up
Is 'Sluggish Cognitive Tempo' a New Disorder or an Extension of ADHD?
Artificial Blood on an Industrial Scale
Mapping Gene Expression in the Fetal Brain
Gene Variant Puts Women at Higher Risk of Alzheimer’s Than It Does Men, Study Finds
Traces of Trauma in Sperm RNA
Lab-Grown Private Parts: Vagina Implants Cure Rare Disorder
Gut-Eating Amoeba Caught on Film
Gene Therapy Successfully Regenerates an Old Organ Inside a Living Animal
Bees Exposed to Fungicide More Vulnerable to Nosema Parasite
Obokata Mentor, Co-Author: STAP Cells Just A ‘Hypothesis’ Lees meer

In Stem-Cell Research, Health Benefits Outweigh the Risks Of Copying Humans

Human Somatic Cell Nuclear Transfer Using Adult Cells

Conversion of Quiescent Niche Cells to Somatic Stem Cells Causes Ectopic Niche Formation in the Drosophila Testis

Auxetic Nuclei in Embryonic Stem Cells Exiting Pluripotency

Pathways Disrupted in Human ALS Motor Neurons Identified through Genetic Correction of Mutant SOD1

Multifaceted Regulation of Somatic Cell Reprogramming by mRNA Translational Control

Two miRNA Clusters Reveal Alternative Paths in Late-Stage Reprogramming

Photo Reference: Courtesy of Dr. Chris Smith - The Naked Scientists

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Ep. 16: Stem Cell Scientist in Washington?

8 april 2014 · 1 uur 12 min
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Guest:
In this episode we bring on Dr. Raja Kittappa, a stem cell scientist who has recently decided to leave science and run for congress.
Resources and Links
Brain Activation during Human Male Ejaculation
Experimental Cancer Drug Reverses Schizophrenia in Adolescent Mice
First Synthetic Yeast Chromosome Revealed
Party Drug Ketamine Could Help People with Severe Depression
Experimental Compound FRAX486 Reverses Signs of Fragile X In Mice
Researchers Identify Good Bacteria That Protects against HIV
MIT Researchers Develop Living Material Using E. coli
Disorganized Cortical Patches Suggest Prenatal Origin of Autism
Blood Test of 4 Biomarkers Predicts Death within 5 Years
Gene Family Linked To Brain Evolution Implicated in Severity of Autism Symptoms
HPV-Linked Throat Cancer May Have Telltale First Symptoms
Mugshots Built from DNA Data
Genetic Factor Contributes to Forgetfulness
Study: Climate Change Accelerates Greenland Ice Loss
Gene Editing of CCR5 in Autologous CD4 T Cells of Persons Infected with HIV
Human Nose Can Detect More Than 1 Trillion Smells, Scientists Discover
Scientists Find Gene Which Is Linked to Exceptionally Low IQ in Children
Stem Cell Scientist Guilty of Falsifying Data
Ancient Virus DNA Gives Stem Cells the Power to Transform
Modeling ALS with iPSCs Reveals that Mutant SOD1 Misregulates Neurofilament Balance in Motor Neurons
Intrinsic Membrane Hyperexcitability of Amyotrophic Lateral Sclerosis Patient-Derived Motor Neurons
Telomerase Protects Werner Syndrome Lineage-Specific Stem Cells from Premature Aging
Mouse SCNT ESCs Have Lower Somatic Mutation Load Than Syngeneic iPSCs
Dynamics of HSPC Repopulation in Nonhuman Primates Revealed by a Decade-Long Clonal-Tracking Study
Combined Hydrogels That Switch Human Pluripotent Stem Cells From Self-Renewal to Differentiation
Mutations in USP9X Are Associated with X-Linked Intellectual Disability and Disrupt Neuronal Cell Migration and Growth
Photo Reference: Courtesy of Dr. Raja Kittappa Lees meer

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Ep.15: Melanoma and Zebrafish Featuring Dr. Leonard Zon

21 maart 2014 · 1 uur 14 min
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Guest:
In this episode, we bring on an internationally recognized stem cell and cancer researcher Dr. Leonard Zon from Harvard Medical School and Boston Children's Hosital. Dr. Zon talks to us about his work using zebrafish as a model to study cancer and melanoma and tells some really funny stories on his experiences with these fish.
Resources and Links
Trends In Atmospheric Carbon Dioxide In Mauna Loa, Hawaii
Gel Protects Monkeys from H.I.V. after Sex, Study Finds
Genetic Modification and Screening in Rat Using Haploid Embryonic Stem Cells
Telescope Captures View of Gravitational Waves
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
Environmental and State-Level Regulatory Factors Affect the Incidence of Autism and Intellectual Disability
Respiratory Failure, Cleft Palate and Epilepsy in the Mouse Model of Human Xq22.1 Deletion Syndrome
CDC Warns Untreatable Gonorrhea Could Spread Like Wildfire
In Rare Case, Woman with H.I.V. Infects Female Sex Partner, C.D.C. Says
Obesity-Associated Variants within FTO Form Long-Range Functional Connections with IRX3
Hydrous Mantle Transition Zone Indicated By Ringwoodite Included within Diamond
Human C-Tactile Afferents Are Tuned to the Temperature of a Skin-Stroking Caress
Shorter Telomeres with High Telomerase Activity are Associated with Raised Allostatic Load and Impoverished Psychosocial Resources
Biomarkers Could Predict Alzheimer's Before It Starts
Confusions About Totipotency: Stem Cells Are Not Embryos
Mechanical Memory and Dosing Influence Stem Cell Fate
Cell-Autonomous Correction of Ring Chromosomes in Human Induced Pluripotent Stem Cells
C9orf72 Nucleotide Repeat Structures Initiate Molecular Cascades of Disease
Haematopoietic Stem Cells Require a Highly Regulated Protein Synthesis Rate
High-Efficiency Motor Neuron Differentiation from Human Pluripotent Stem Cells and the Function Ofislet-1
Photo Reference: Courtesy of Dr. Leonard Zon Lees meer

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Ep.14: Direct Reprogramming Featuring Dr. Justin Ichida

10 maart 2014 · 1 uur 8 min
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Guest:
Over the past few weeks some really exciting papers came out describing the reprogramming of one cell into another, a process called Direct Reprogramming. On this episode we talk to Dr. Justin Ichida from the University of Southern California who uses the latest reprogramming techniques in his lab to study neural disease. His current research is focused on using patient-specific disease models to define the mechanisms that lead to neuronal loss in ALS and frontotemporal dementia.
Resources and Links
University of Southern California - The Ichida Lab – Board California Institute for Regenerative Medicine (CIRM) Center for Regenerative Medicine and Stem Cell Research
Early Treatment Is Found to Clear H.I.V. in a Second Baby
Why Can You Remember Your Dreams? Researchers Uncover Why Only Some People Can Recall Them in the Morning
Acetaminophen In Pregnancy Linked to ADHD in Kids, Study Finds
Study Uncovers New Pathway of Melanoma Metastasis
New Research Finds Direct Connection Between Acupuncture and Processes That Alleviate Sepsis
'Largest Ever' Trial of Adult Stem Cells in Heart Attack Patients Begins
This Company Wants to Make In Vitro Meat From Celebrities’ Stem Cells
USPTO Issues Patent For Fraudulent Stem Cell Procedure
Isolation Of Human Induced Pluripotent Stem Cell-Derived Dopaminergic Progenitors By Cell Sorting For Successful Transplantation
Coordination Of Engineered Factors With TET1/2 Promotes Early-Stage Epigenetic Modification during Somatic Cell Reprogramming
Small Molecules Facilitate the Reprogramming of Mouse Fibroblasts into Pancreatic Lineages
Direct Reprogramming of Human Fibroblasts to Functional and Expandable Hepatocytes
Human Hepatocytes with Drug Metabolic Function Induced from Fibroblasts by Lineage Reprogramming
Photo Reference: Courtesy of Dr. Justin Ichida Lees meer

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Alle afleveringen

Ep. 63: “Reprogrammed Stomach” Featuring Dr. Joe Zhou

Ep. 62: “Forever Young” Featuring Dr. Aubrey de Grey

Ep. 61: World Stem Cell Summit 2015

Ep. 60: “Stemcentrx” Featuring Scott Dylla

Ep. 59: “Clinical Grade” Featuring Dr. Tilo Kunath

Ep. 58: “Heart Disease Modeling” Featuring Dr. Lior Gepstein

Ep. 57: “Curiosity” Featuring Duane Fernandez

Ep. 56: “Glia” Featuring Dr. Steven Goldman

Ep. 55: Biomaterials and Stem Cells Featuring Dr. David Mooney

Ep. 54: Stem Cell Lineage Tracing Featuring Dr. Andrew Cohen

Ep. 53: Automated iPS Cells Featuring Dr. Scott Noggle

Ep. 52: Stem Cells and Autism Featuring Dr. Flora Vaccarino

Ep. 51: Stem Cell Theranostics Featuring Dr. Chris Armstrong

Ep. 50: Global Perspective Featuring George Daley of the Harvard Stem Cell Institute

Ep. 49: SCP Sweden Part 2 – Live Interviews from the ISSCR Conference in Sweden 2015

Ep. 48: SCP Sweden Part 1 – Live Interviews from the ISSCR Conference in Sweden 2015

Ep. 47: The Stem Cell Podcast Round Up Only

Ep. 46: “ISSCR Conference Preview” Featuring Dr. Heather Rooke

Ep. 45: “Differentiation” Featuring Alex Hannay

Ep. 44: “Saratoga Stem Cell” Featuring Greg Smith, Christy Allen, Samantha Morris and Evangelos Kiskinis

Ep. 43: “A Closer Look At Stem Cells” Featuring Dr. Megan Munsie and Dr. Mario D’Cruz

Ep. 42: “Neurogenesis” Featuring Dr. Fred Gage

Ep. 41: “Chromosomal Disorders” Featuring Dr. Eirini Papapetrou

Ep. 40: “Gene Editing Mistakes” Featuring Dr. Frederick Alt

Ep. 39: “Stressed Out Cells” Featuring Dr. Rhonda Newman

Ep. 38: Cell Transplant Therapy Featuring Dr. Lorenz Studer

Ep. 37: Repairing The Heart Featuring Dr. Christine Mummery

Ep. 36: Disease Model Tools Featuring Dr. David Piper

Ep. 35: CART Therapies Featuring Dr. Maria Themeli

Ep. 34: 2014 Stem Cell Podcast Round Up

Ep. 33: Skin Repair Featuring Dr. Marius Wernig

Ep. 32: Parkinson’s Cell Therapy Featuring Dr. Malin Parmar

Ep. 31: Cell Stem Cell Editor featuring Dr. Christina Lilliehook

Ep. 30: Nobel Conversation Featuring Dr. Harold Varmus

Ep. 29: Brain Science Podcast Featuring Dr. Ginger Campbell

Ep. 28: New York Times and Stem Cells Featuring Karen Weintraub

Ep. 27: MS and Stem Cells Featuring Dr. Valentina Fossati

Ep. 26: Pluripotency Network Featuring Dr. Austin Smith

Ep. 25: STAP Recap Featuring Dr. Paul Knoepfler

Ep. 24: Sperm Stem Cells Featuring Dr. Marco Seandel

Ep. 23: Vascular Niche Featuring Dr. Daylon James

Ep. 22: Novel Enhancers Featuring Dr. Paul Tesar

EP. 21 The International Society for Stem Cell Research (ISSCR) Conference 2014

Ep. 20: SCNT Featuring Dr. Dieter Egli

Ep. 19: Saratoga Stem Cell Conference Review and 5 Interviews

Ep. 18: Lou Gehrig’s Update Featuring Dr. Kevin Eggan

Ep. 17: Naked Stem Cells Featuring Dr. Chris Smith of The Naked Scientists

Ep. 16: Stem Cell Scientist in Washington?

Ep.15: Melanoma and Zebrafish Featuring Dr. Leonard Zon

Ep.14: Direct Reprogramming Featuring Dr. Justin Ichida