The Stem Cell Podcast

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364 afleveringen, van nieuw naar oud

  1. Ep. 13: STAP Stem Cells and Blogging Featuring Dr. Paul Knoepfler

    23 februari 2014 · 1 uur 9 min

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    Guest:
    STAP stem cells were a new method of generating pluripotent stem cells published in a paper a few weeks ago. When it came out, scientists scratched their heads and wondered whether or not this new method could actually work and be reproducible. Well, while the jury is still out, it is not looking good and we bring on the show one of the most recognized voices of stem cell research, Dr. Paul Knoepfler to discuss the STAP stem cell theory. In addition to running a laboratory, Dr. Knoepfler maintains an amazingly active stem cell blog breaking all the latest stem cell news, and educating the public about stem cells.
    Resources and Links
    Knoepfler Lab Stem Cell Blog
    Stem Cells: An Insiders Guide by Paul Knoepfler
    Expandable Megakaryocyte Cell Lines Enable Clinically Applicable Generation of Platelets from Human Induced Pluripotent Stem Cells
    The Endocannabinoid System Controls Food Intake via Olfactory Processes
    Astrocyte-Derived Endothelin-1 Inhibits Remyelination through Notch Activation
    Rejuvenation of the Muscle Stem Cell Population Restores Strength to Injured Aged Muscles
    Nanog-Independent Reprogramming to iPSCs with Canonical Factors
    Nanog Is Dispensable for the Generation of Induced Pluripotent Stem Cells
    In Vivo Direct Reprogramming of Reactive Glial Cells into Functional Neurons after Brain Injury and in an Alzheimer’s Disease Model
    NPTX1 Regulates Neural Lineage Specification from Human Pluripotent Stem Cells
    Photo Reference: Courtesy of Dr. Paul Knoepfler
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  2. Ep. 12: Cancer and Stem Cells Featuring Dr. Sean Morrison

    10 februari 2014 · 1 uur 18 min

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    Guest:
    In this episode, we interview another stem cell pioneer, Dr. Sean Morrison, who is internationally recognized for his work in understanding the mechanisms of stem cell regulatory mechanisms and how this is relevant in cancer. In the science roundup we cover zombie bees, stem cells for baldness, dipping cells in acid to make stem cells, and how to identify the difference between iPSCs and hESCs.
    Photo Reference: Courtesy of Dr. Chad Cowan
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  3. Ep. 11: Stem Cell Core Facilities Featuring Dr. Mark Tomishima

    27 januari 2014 · 1 uur 19 min

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    Guest:
    Dr. Mark Tomishima, director of the SKI Stem Cell Research Facility located in New York City joins us for this episode. Dr. Tomishima tells us about what his and other core facilities do for stem cell researchers locally and abroad, as well as various projects his group is working on. We then go through the science roundup discussing everything from a new herpes drug, to heart cell propelled sperm looking bio-bots, to stem cell-derived 3D kidneys.
    Photo Reference: Courtesy of Dr. Mark Tomishima
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  4. Ep. 10: RPE and Macular Degeneration Featuring Dr. Sally Temple

    14 januari 2014 · 1 uur 13 min

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    Guest:
    In this episode, we bring on a true pioneer in the stem cell field, Dr. Sally Temple, scientific director of the Neural Stem Cell Institute. Dr. Temple discovered that stem-like cells exist in the adult brain in the late 80s and has since gone on to characterize these cells extensively. Her group has recently discovered a novel stem cell in the eye that they plan to use as a new therapy for macular degeneration, the leading cause of blindness. In the science roundup we talk about everything from caffeine boosting memory, to the possibility of the Y chromosome disappearing.
    Photo Reference: Courtesy of Dr. Sally Temple
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  5. Ep. 9: 2013 Roundup

    2 januari 2014 · 1 uur

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    Happy new year Stem Cell Podcast listeners, we are back to start off with an episode that looks backs at a year of science in 2013 and gives you our top 10 studies from both the stem cell world and science as a whole. We discuss a variety of topics from human cloning to going interstellar. It's been a great year for science despite threats to funding. Let's make sure science funding increases in 2014. Enjoy! Lees meer

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  6. Ep. 8: Aged Neurons in a Dish Featuring Justine Miller

    13 december 2013 · 1 uur 7 min

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    Guest: Lees meer

    Justine Miller, a PhD candidate from Lorenz Studer's lab at Memorial Sloan Kettering, joins us to discuss her recent paper in Cell Stem Cell showing how to age stem cell-derived neurons in the culture dish. In our science round up, we discuss everything from the ground state in stem cells to male birth control. We then dive into other stem cell topics including reprogramming via protein transduction and CRISPR-mediated gene repair.
    Photo Reference: Courtesy of Justine Miller, PhD candidate

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  7. Ep. 7: Holiday Science Break

    30 november 2013 · 54 min

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    We are back with a stem cell "quickie" for the holidays. In our science round up we talk mummified ribs, fear of snakes, and genes associated with an increased risk of Alzheimer's disease. We then discuss the latest stem cell news, papers, and a conference recently held in Los Angeles. Lees meer

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  8. Ep. 6: ALS and C9orf72 Featuring Dr. Asif Maroof

    20 november 2013 · 1 uur 5 min

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    Guest:
    We interview Dr. Asif Maroof, a post-doctoral fellow in the lab of Dr. Kevin Eggan at the Harvard Stem Cell Institute to talk about his latest paper in Nature Neuroscience describing a gene implicated in ALS a.k.a Lou Gehrig's disease. Our science roundup includes new Alzheimer's targets, bitter tasting genes, polio, and bacteria-fighting zinc.
    Photo Reference: Courtesy of Dr. Asif Maroof
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  9. Ep. 5: Parkinson’s Disease and Stem Cells

    9 november 2013 · 1 uur 7 min

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    In this episode we do things a little different. Since we both work on Parkinson's disease we will not be featuring a guest. Instead, we will talk about the etiology of the disease and cover various forms of therapy - with an emphasis on stem cells. Our science roundup includes: CO2 levels, "Project Einstein", paper retraction rates, SARS, and plexins. Lees meer

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  10. Ep. 4: 3D Pancreas and ISSCR Featuring Dr. Carl P. Wonders

    27 oktober 2013 · 1 uur 5 min

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    Guest:
    In this episode, we welcome Dr. Carl P. Wonders, the scientific affairs manager for the International Society for Stem Cell Research (ISSCR). We discuss the annual meeting, science outreach, and long-term goals for the society. Our science round-up segment includes: RNAi pesticides, atomic clocks, corked wine and TCA, and review of an open-access journal investigation.
    Photo Reference: Courtesy of Dr. Carl Wonders
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  11. Ep. 3: Blood From Stem Cells Featuring Dr. Daylon James

    16 oktober 2013 · 1 uur 3 min

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    Guest:
    In this episode, we interview stem cell biologist Dr. Daylon James to discuss the field of blood stem cells; different strategies and clinical implications. Our science round up this week includes the CTE issue in the NFL, Nobel laureates, and gut bacteria.
    Photo Reference: Courtesy of New York Social Diary
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  12. Ep. 2: Reprogramming Brakes and Government Shutdown Featuring Dr. Jacob Hanna

    11 oktober 2013 · 54 min

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    Guest:
    In this episode we welcome Dr. Jacob Hanna from Weizmann Institute of Science. Dr. Hanna’s group recently published in Nature describing a method for 100% reprogramming efficiency. We also do our usual Stem Cell Podcast roundup, which includes anti-acne bacteria, Eric Kandel’s RB-AB 48 Alzheimer’s target and others.
    Photo Reference: Courtesy of Dr. Jacob Hanna
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  13. Ep. 1: In Vivo Reprogramming and Mini Brains Featuring Dr. Juergen Knoblich

    28 september 2013 · 47 min

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    In this episode we start off with a quick general science news roundup before discussing two new papers in stem cell research. Both papers appeared in the journal Nature. The first describes a novel method of reprogramming somatic cells into induced pluripotent stem cells in vivo, and other describes a method to make a mini cerebral cortex from human embryonic stem cells. The senior author on the latter study, Dr. Juergen Knoblich, joins us to discuss this paper and its implications. Lees meer
  14. Introduction

    21 september 2013 · 25 min

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    Welcome to the stem cell podcast hosted by Dr.'s Christopher Fasano and Yosif Ganat. Here we will give a brief introduction to the biology of stem cells and the future direction of this podcast. Lees meer

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