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Jul 23, 2021 This Week in Cardiology Podcast
23 juli 2021 · 24 min
COVID-19 messaging, coffee, CTA and statins, and Watchman problems are the topics discussed by John Mandrola, MD, in this week's podcast. https://www.medscape.com/twic Lees meer
1- COVID-19:
- COVID-19 Cases in US Triple Over 2 Weeks Amid Misinformation https://www.medscape.com/viewarticle/955269
- Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant https://www.nejm.org/doi/full/10.1056/NEJMoa2108891
- What Really Happened With that Weird Yankees COVID Outbreak https://nymag.com/intelligencer/2021/05/what-really-happened-with-that-weird-yankees-covid-outbreak.html
2- Coffee:
- Coffee Not Linked to Increased Arrhythmia Risk in New Study https://www.medscape.com/viewarticle/954992
- Coffee Consumption and Incident Tachyarrhythmias https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2782015
- Another Cup of Coffee Without an Arrhythmia, Please https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2782021
3- CTA and Statins:
- CTA May Guide Primary Prevention Statins in Nonobstructive CAD https://www.medscape.com/viewarticle/955030
- Reduction of Myocardial Infarction and All-Cause Mortality Associated to Statins in Patients Without Obstructive CAD https://www.jacc.org/doi/full/10.1016/j.jcmg.2021.05.022
4- Left Atrial Appendage Closure:
- Five Risk Factors May Predict Thrombus on LAA Occlusion Implants https://www.medscape.com/viewarticle/955131
- Predictors of Device-Related Thrombus Following Percutaneous Left Atrial Appendage Occlusion https://www.jacc.org/doi/full/10.1016/j.jacc.2021.04.098
- Device-Related Thrombus After Left Atrial Appendage Occlusion https://www.jacc.org/doi/10.1016/j.jacc.2021.05.028
Features:
- Does Coffee Make Your Heart Flutter? https://www.medscape.com/viewarticle/954996
- Enough With the Coffee Research and Other Distractions https://www.medscape.com/viewarticle/883709
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July 16, 2021 This Week in Cardiology Podcast
16 juli 2021 · 19 min
COVID-19, Ivermectin, a dissolving pacer, clinician well-being, and finerenone are discussed this week. Lees meer
1 COVID-19
US 'Losing Time' Against Delta Variant, NIH Chief Says https://www.medscape.com/viewarticle/954882
Ivermectin for COVID: How Do We Know What to Believe? https://www.medscape.com/viewarticle/954681
2 Dissolving Pacemaker
Dissolving Pacemaker Impressive in Early Research https://www.medscape.com/viewarticle/954774
3 Clinician Well-being
Global Heart Organizations Unite to Promote Clinician Well-Being https://www.medscape.com/viewarticle/954803
Clinician Well-Being: Addressing Global Needs for Improvements in the Health Care Field A Joint Opinion From the American College of Cardiology, American Heart Association, European Society of Cardiology, and the World Heart Federation https://www.jacc.org/toc/jacc/0/0
From Triple to Quadruple Aim: Care of the Patient Requires Care of the Provider https://www.annfammed.org/content/12/6/573.full
Bullying in Academic Medicine Rife, Underreported https://www.medscape.com/viewarticle/954709
4 Finerenone
FDA Approves Finerenone (Kerendia) for Slowing CKD in Type 2 Diabetes https://www.medscape.com/viewarticle/954606
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Questions or feedback, please contact news@medscape.net
Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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July 2, 2021 This Week in Cardiology Podcast
2 juli 2021 · 20 min
COVID-19, mRNA-vaccine-induced myocarditis, type 2 diabetes in kids, optimal medical therapy for CAD, and Alcohol are the topics discussed by John Mandrola, MD, in this week's podcast. https://www.medscape.com/twic Lees meer
1-COVID
- Fast-spreading Delta Variant, Vaccination Rates, Reintroduction of Indoor Masks: COVID-19 Global Weekly Highlights https://www.medscape.com/viewarticle/940446
- Health care 'breaking point': Cox confirms some Springfield COVID-19 patients transferred to St. Louis, Kansas City https://www.news-leader.com/story/news/local/ozarks/2021/06/29/springfield-covid-delta-variant-missouri-hospitals-cox-some-patients-transferred-vaccines/7787970002/
2- COVID Vaccine-Induced Myocarditis
- New Details of Myocarditis Linked to COVID Vaccines https://www.medscape.com/viewarticle/954061
- Myocarditis Following Immunization With mRNA COVID-19 Vaccines in Members of the US Military https://jamanetwork.com/journals/jamacardiology/fullarticle/2781601
- Patients With Acute Myocarditis Following mRNA COVID-19 Vaccination https://jamanetwork.com/journals/jamacardiology/fullarticle/2781602
3- Diabetes in the Clinic
- 'Staggering' Doubling of Type 2 Diabetes in Kids During Pandemic https://www.medscape.com/viewarticle/953816
4- Optimal Medical Therapy
- OMT 'Best Insurance' for Extended Survival After Revascularization https://www.medscape.com/viewarticle/953959
- Impact of Optimal Medical Therapy on 10-Year Mortality After Coronary Revascularization https://doi.org/10.1016/j.jacc.2021.04.087
- Defining the Proper SYNTAX for Long-Term Benefit of Myocardial Revascularization With Optimal Medical Therapy https://doi.org/10.1016/j.jacc.2021.04.088
- Percutaneous Coronary Intervention versus Coronary-Artery Bypass Grafting for Severe Coronary Artery Disease. https://www.nejm.org/doi/full/10.1056/nejmoa0804626
- Percutaneous coronary intervention versus coronary artery bypass grafting in patients with three-vessel or left main coronary artery disease: 10-year …
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Jun 25, 2021 This Week in Cardiology Podcast
25 juni 2021 · 21 min
Myocarditis and the COVID vaccine, lipid lowering guidelines, financial toxicity, and deprescribing statins are the topics covered by John Mandrola, MD, in this week's podcast. https://www.medscape.com/twic Lees meer
1 – COVID
Varied COVID Vaccination Rates May Lead to 'Two Americas' https://www.medscape.com/viewarticle/953658
Nearly All COVID Deaths in US Are Now Among Unvaccinated https://www.medscape.com/viewarticle/953703
2 - COVID Vaccine Myocarditis
FDA to Add Myocarditis Warning to mRNA COVID-19 Vaccines https://www.medscape.com/viewarticle/953647
3 – Lipid Guidelines
Clinicians Slow to Implement Lipid-Lowering Guidelines: GOULD Registry https://www.medscape.com/viewarticle/953688
- Use of Lipid-Lowering Therapies Over 2 Years in GOULD, a Registry of Patients With Atherosclerotic Cardiovascular Disease in the US https://jamanetwork.com/journals/jamacardiology/fullarticle/2780713
4 - Financial Toxicity
Financial Burden Higher With CVD Than Cancer https://www.medscape.com/viewarticle/953687
- Atherosclerotic Cardiovascular Disease, Cancer, and Financial Toxicity Among Adults in the United States https://www.jacc.org/doi/10.1016/j.jaccao.2021.02.006
5 - Deprescribing Statins
Stopping Statins Linked to Death, CV Events in Elderly https://www.medscape.com/viewarticle/953545
- Cardiovascular Outcomes and Mortality Associated With Discontinuing Statins in Older Patients Receiving Polypharmacy https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2780952
- Effect of rosuvastatin in patients with chronic heart failure (the GISSI-HF trial): a randomised, double-blind, placebo-controlled trial https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(08)61240-4/fulltext
- Rosuvastatin in Older Patients with Systolic Heart Failure https://www.nejm.org/doi/full/10.1056/NEJMoa0706201
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June 18, 2021 This Week in Cardiology
19 juni 2021 · 22 min
COVID vaccine myocarditis, Christian Eriksen and sudden cardiac death, therapeutic hypothermia, and revascularization of stable CAD are the topics John Mandrola, MD, discusses in this week's podcast. Lees meer
https://www.medscape.com/twic
1- COVID-Vaccine-Myocarditis
AHA: Don't Delay COVID Shot While CDC Reviews Myocarditis Cases https://www.medscape.com/viewarticle/953233
Myocarditis after BNT162b2 and mRNA-1273 Vaccination https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.121.055913
2- Christian Eriksen
Christian Eriksen: un survivant qui doit nous inspirer
https://francais.medscape.com/voirarticle/3607279
Danish Soccer Player Suffered Cardiac Arrest During Euro Match
https://www.webmd.com/news/20210614/danish-soccer-player-suffered-cardiac-arrest-during-euro-match
Point/Counterpoint on Halting Implantation of the Subcutaneous ICD https://www.jacc.org/doi/10.1016/j.jacep.2021.03.006
3- Therapeutic Hypothermia
Trial Supports Therapeutic Hypothermia in Nonshockable Cardiac Arrest https://www.medscape.com/viewarticle/919855
Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest
https://www.nejm.org/doi/full/10.1056/NEJMoa2100591
PulmCrit – A history of hypothermia for cardiac arrest, 2002-2021 (RIP)
https://emcrit.org/pulmcrit/ttm2/
4 - Revascularization of Stable CAD
Meta-analysis Muses Over ISCHEMIA Message Had Trial Lasted Longer https://www.medscape.com/viewarticle/951498
Cardiac mortality in patients randomised to elective coronary revascularisation plus medical therapy or medical therapy alone: a systematic review and meta-analysis https://doi.org/10.1093/eurheartj/ehab246
Impact of revascularisation on outcomes in chronic coronary syndromes: a new meta-analysis with the same old biases?
https://doi.org/10.1093/eurheartj/ehab330
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June 11, 2021 This Week in Cardiology Podcast
11 juni 2021 · 19 min
COVID vaccine myocarditis, AF post-stroke, semaglutide, and iPhones and cardiac devices are the topics John Mandrola, MD, discusses in this week's podcast. https://www.medscape.com/twic Lees meer
COVID-Vaccine-Myocarditis
More Evidence Links COVID Vaccines to Rare Cases of Myocarditis in Youth https://www.medscape.com/viewarticle/952905
- Symptomatic Acute Myocarditis in Seven Adolescents Following the Pfizer-BioNTech COVID-19 Vaccination https://pediatrics.aappublications.org/content/early/2021/06/04/peds.2021-052478
- At Least 18 Cases of Apparent Heart Problems in Young People in CT After COVID-19 Vaccine https://www.nbcconnecticut.com/news/coronavirus/connecticut-confirms-at-least-18-cases-of-apparent-heart-problems-in-young-people-after-covid-19-vaccination/2494534/
- C.D.C. Is Investigating a Heart Problem in a Few Young Vaccine Recipients https://www.nytimes.com/2021/05/22/health/cdc-heart-teens-vaccination.html
- EMA Statement: https://www.ema.europa.eu/en/news/meeting-highlights-pharmacovigilance-risk-assessment-committee-prac-3-6-may-2021
- Is the Second Shot Giving Young Men a Dangerous Heart Condition? https://nymag.com/intelligencer/2021/06/israel-detects-link-between-myocarditis-and-covid-vaccine.html
- Report to FDA https://www.fda.gov/media/150054/download
AF and Stroke
Evidence Mounts for Implantable AF Monitoring After Stroke https://www.medscape.com/viewarticle/952325
- The STROKE-AF Randomized Clinical Trial https://jamanetwork.com/journals/jama/fullarticle/2780490
- The PER DIEM Randomized Clinical Trial https://jamanetwork.com/journals/jama/fullarticle/2780491
Obesity
FDA Approves 'Game Changer' Semaglutide for Weight Loss https://www.medscape.com/viewarticle/952441
iPhone 12 and Cardiac Device
Evidence Builds for iPhone 12 Interference With Cardiac Devices https://www.medscape.com/viewarticle/952780
- Magnetic Interference on Cardiac Implantable Electronic Devices From Apple iPhone MagSafe Technology https://www.ahajournals.org/doi/10.…
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May 21, 2021 This Week in Cardiology Podcast
21 mei 2021 · 28 min
John Mandrola, MD, presents an ACC 2021 recap. https://www.medscape.com/twic Lees meer
ACC 2021 Reveiw
I -- Left Atrial Appendage Closure
LAAOS III: Surgical LAA Closure Cuts AF Stroke Risk by One Third https://www.medscape.com/viewarticle/951232
- Left Atrial Appendage Occlusion during Cardiac Surgery to Prevent Stroke https://www.nejm.org/doi/full/10.1056/NEJMoa2101897
Watchman Registry: 1-Year Stroke Estimates Reassuringly Low https://www.medscape.com/viewarticle/951235
II - Angiotensin-Neprilysin Inhibition
PARADISE-MI: Sacubitril/Valsartan Can't Beat Ramipril in Patients With Acute MI https://www.medscape.com/viewarticle/951236
Life Trial
Rationale Paper: https://doi.org/10.1016/j.jchf.2020.05.005
III - Renal Denervation
Ultrasound Renal Denervation Drops BP in Patients on Triple Therapy https://www.medscape.com/viewarticle/951248
IV -- Clopidogrel vs ASA post Stent
HOST-EXAM: Clopidogrel Beats Aspirin as Monotherapy After Stenting https://www.medscape.com/viewarticle/951294
- Aspirin versus clopidogrel for chronic maintenance monotherapy after percutaneous coronary intervention (HOST-EXAM): an investigator-initiated, prospective, randomised, open-label, multicentre trial https://doi.org/10.1016/S0140-6736(21)01063-1
V -- AF Ablation in HF
RAFT-AF, Despite Itself, Hints at Advantage for Ablation Rhythm Control in Heart Failure With AF. https://www.medscape.com/viewarticle/951326
VI -- Rivaroxaban in COVID-19 – ACTION Trial
Therapeutic Rivaroxaban Dose: Risk Outweighs Benefit in Stable COVID https://www.medscape.com/viewarticle/951475
VII -- REHAB-HF Trial
Novel Rehab Program Fights Frailty, Boosts Capacity in Advanced HF https://www.medscape.com/viewarticle/951244
- Physical Rehabilitation for Older Patients Hospitalized for Heart Failure https://www.nejm.org/doi/full/10.1056/NEJMoa2026141
VIII – ASA 81 vs 325 – ADAPTABLE Trial
ADAPTABLE: Low-Dose Aspirin as Good as High-Dose in CHD? https://www.medscape.com/viewarticle/951230
- Comparative Effec…
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May 14, 2021 This Week in Cardiology Podcast
14 mei 2021 · 17 min
The upcoming ACC meeting, polypharmacy, finerenone, and ethics and professionalism are the topics covered by John Mandrola, MD, in this week's podcast. https://www.medscape.com/twic Lees meer
ACC Preview:
ACC.21 Looks to Repeat Success Despite Pandemic Headwinds https://www.medscape.com/viewarticle/950836
- Level and Prevalence of Spin in Published Cardiovascular Randomized Clinical Trial Reports With Statistically Nonsignificant Primary Outcomes: A Systematic Review https://pubmed.ncbi.nlm.nih.gov/31050775/
Polypharmacy
Hypertension Worsened by Commonly Used Prescription Meds https://www.medscape.com/viewarticle/950724
Finerenone
Finerenone Scores Second Pivotal-Trial Success in Diabetic Kidney Disease https://www.medscape.com/viewarticle/951027
- Effect of Finerenone on Chronic Kidney Disease Outcomes in Type 2 Diabetes https://www.nejm.org/doi/full/10.1056/NEJMoa2025845
Ethics and Professionalism
AHA/ACC Guidance on Ethics, Professionalism in Cardiovascular Care https://www.medscape.com/viewarticle/951018
- 2020 American Heart Association and American College of Cardiology Consensus Conference on Professionalism and Ethics: A Consensus Conference Report https://www.ahajournals.org/doi/10.1161/CIR.0000000000000963
Features:
Mandrola Previews the 2021 (Virtual) American College of Cardiology Scientific Sessions https://www.medscape.com/viewarticle/950797
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May 7, 2021 This Week in Cardiology Podcast
8 mei 2021 · 20 min
COVID-19 and BMI, TAVR vs SAVR, subcutaneous ICD, SGLT2 inhibitors, and physician-Moms are the topics John Mandrola, MD, discusses in this week's podcast. https://www.medscape.com/twic Lees meer
COVID-19
COVID-19 Severity Starts in Normal BMI Range, Especially in Young https://www.medscape.com/viewarticle/950568
- Associations between body-mass index and COVID-19 severity in 6·9 million people in England: a prospective, community-based, cohort study https://www.thelancet.com/journals/landia/article/PIIS2213-8587(21)00089-9/fulltext
TAVR vs SAVR
VARC-3 Sets Goalpost for Future Aortic Valve Trials https://www.medscape.com/viewarticle/950012
- Valve Academic Research Consortium 3: updated endpoint definitions for aortic valve clinical research https://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehaa799/6237954
TAVR Availability
Patchy Growth of TAVR Programs Leaves Poorer Communities Behind https://www.medscape.com/viewarticle/950316
S-ICD
Trade-offs Between Subcutaneous, Transvenous ICDs on Display in EFFORTLESS https://www.medscape.com/viewarticle/950328
- Implant and Midterm Outcomes of the Subcutaneous Implantable Cardioverter-Defibrillator Registry: The EFFORTLESS Study https://doi.org/10.1016/j.jacc.2017.06.040
- Reduction in Inappropriate Therapy and Mortality through ICD Programming https://www.nejm.org/doi/full/10.1056/NEJMoa1211107
- Low inappropriate shock rates in patients with single- and dual/triple-chamber implantable cardioverter-defibrillators using a novel suite of detection algorithms: PainFree SST trial primary results https://doi.org/10.1016/j.hrthm.2015.01.017
Dapagliflozin and CKD
FDA Approves Dapagliflozin (Farxiga) for Chronic Kidney Disease https://www.medscape.com/viewarticle/950329
Features
New Physician Moms Need More Resources and Less Guilt in the Workplace https://www.medscape.com/viewarticle/949765
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Apr 30, 2021 This Week in Cardiology Podcast
30 april 2021 · 23 min
COVID-19 and global vaccinations, AF screening, conduction-system pacing, FDA ban on menthol tobacco, and a heartfelt essay are the topics John Mandrola, MD, discusses in this week's podcast. https://www.medscape.com/twic Lees meer
COVID-19
Indians Rush for COVID-19 Vaccines as Death Toll Passes 200,000 https://www.medscape.com/viewarticle/950095
- Vaccine Breakthrough Infections with SARS-CoV-2 Variants https://www.nejm.org/doi/full/10.1056/NEJMoa2105000
AF Screening:
Modest Clinical Gain for AF Screening of Asymptomatic Elderly: STROKESTOP https://www.medscape.com/viewarticle/949950
- Mass Screening for Untreated Atrial Fibrillation
The STROKESTOP Study https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.114.014343
- Does screening for disease save lives in asymptomatic adults? Systematic review of meta-analyses and randomized trials https://pubmed.ncbi.nlm.nih.gov/25596211/
- Toward evidence-based medical statistics. 2: The Bayes factor https://pubmed.ncbi.nlm.nih.gov/10383350
Conduction System Pacing
Keeping Pace: His-Bundle CRT for Heart Failure Impresses in Second Randomized Trial https://www.medscape.com/viewarticle/950037
- A Randomized Trial of His pacing versus Biventricular pacing in Symptomatic Heart Failure Patients with left bundle branch block (His-Alternative) https://www.jacc.org/doi/10.1016/j.jacep.2021.04.003
- His Corrective Pacing or Biventricular Pacing for Cardiac Resynchronization in Heart Failure https://www.jacc.org/doi/full/10.1016/j.jacc.2019.04.026
FDA
FDA Moves to Ban Menthol in Tobacco Products https://www.medscape.com/viewarticle/950223
Features:
Losing Both Parents During COVID: A Physician's 'Unwitnessed Grief' https://www.medscape.com/viewarticle/949490
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Apr 23, 2021 This Week in Cardiology Podcast
23 april 2021 · 23 min
Cardiac status post COVID-19 in athletes, AF ablation, and bias against procedural doctors are the topics covered by John Mandrola, MD, in this week's podcast https://www.medscape.com/twic Lees meer
COVID-19
COVID-19 Outbreak Associated with a SARS-CoV-2 R.1 Lineage Variant in a Skilled Nursing Facility After Vaccination Program — Kentucky, March 2021 https://www.cdc.gov/mmwr/volumes/70/wr/mm7017e2.htm
Professor Zeynep Tufekci Newsletter: https://www.theinsight.org/p/facts-are-pieces-of-a-puzzle-not
Post-COVID-19 Cardiac Involvement in NCAA athletes
SARS-CoV-2 Cardiac Involvement in Young Competitive Athletes https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.121.054824
AF and Durable PV isolation
Paroxysmal AF Can Recur but Burden Plunges After 'Durable' Ablation https://www.medscape.com/viewarticle/949566
Radiofrequency vs. Cryoballoon Catheter Ablation for Paroxysmal Atrial Fibrillation: Durability of Pulmonary Vein Isolation and Effect on AF Burden: The RACE-AF Randomized Controlled Trial https://www.ahajournals.org/doi/10.1161/CIRCEP.120.009573
Bias Against Procedures:
Apr 9, 2021 This Week in Cardiology Podcast https://www.medscape.com/viewarticle/949000
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Apr 16, 2021 This Week in Cardiology Podcast
16 april 2021 · 18 min
COVID-19 vaccine-related clotting, vitamin D, anticoagulation strategies before PCI, and a good intervention at end of life are the topics John Mandrola, MD, discusses in this week's podcast. https://www.medscape.com/twic Lees meer
COVID-19:
How Some COVID-19 Vaccines Could Cause Rare Blood Clots https://www.medscape.com/viewarticle/949262
FAQ: What to Know About the J&J Vaccine Pause https://www.medscape.com/viewarticle/949231
Vitamin D Screening:
Don't Screen for Vitamin D in General Population, Says US Task Force https://www.medscape.com/viewarticle/949167
Pre-PCI AC Decisions:
Parity Whether Anticoagulation Is Halted or Not for Unplanned Cath https://www.medscape.com/viewarticle/949064
Uninterrupted Oral Anticoagulant Therapy in Patients Undergoing Unplanned Percutaneous Coronary Intervention https://doi.org/10.1016/j.jcin.2021.01.022
Pacemaker or Defibrillator Surgery without Interruption of Anticoagulation https://www.nejm.org/doi/full/10.1056/nejmoa1302946
Continued vs. interrupted direct oral anticoagulants at the time of device surgery, in patients with moderate to high risk of arterial thrombo-embolic events (BRUISE CONTROL-2) https://doi.org/10.1093/eurheartj/ehy413
A Superb Intervention at End of Life:
Use of Comfort Care Increasing After Stroke, May Reduce Costs https://www.medscape.com/viewarticle/949297
Decade‐Long Nationwide Trends and Disparities in Use of Comfort Care Interventions for Patients With Ischemic Stroke https://doi.org/10.1161/JAHA.120.019785
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Apr 9, 2021 This Week in Cardiology Podcast
9 april 2021 · 23 min
COVID-19, COVID-19 vaccines, hybrid AF ablation TAVR and who gets to be called a doctor are the topics by John Mandrola, MD, in this week's podcast. https://www.medscape.com/twic Lees meer
COVID-19
UK Regulators to Offer Under-30s Alternative to AZ COVID Vaccine https://www.medscape.com/viewarticle/948934
- News - Communicating the potential benefits and harms of the Astra-Zeneca COVID-19 vaccine https://wintoncentre.maths.cam.ac.uk/news/communicating-potential-benefits-and-harms-astra-zeneca-covid-19-vaccine/
Hybrid Ablation for Persistent AF
- Hybrid Convergent Procedure for the Treatment of Persistent and Long-Standing Persistent Atrial Fibrillation https://www.ahajournals.org/doi/10.1161/CIRCEP.120.009288
- Converge trial Rationale Paper https://doi.org/10.1016/j.ahj.2020.02.016
- Approaches to Catheter Ablation for Persistent Atrial Fibrillation https://www.nejm.org/doi/full/10.1056/NEJMoa1408288
- Toward evidence-based medical statistics. 2: The Bayes factor https://pubmed.ncbi.nlm.nih.gov/10383350/
TAVR
- TAVR Feasible, Comparable to Surgery in Rheumatic Heart Disease https://www.medscape.com/viewarticle/948832
- Transcatheter Versus Surgical Aortic Valve Replacement in Patients With Rheumatic Aortic Stenosis https://doi.org/10.1016/j.jacc.2021.02.032
- Upsides, Downsides for TAVR, Minimally Invasive AVR https://www.medscape.com/viewarticle/946104
- Minimally invasive surgery versus transcatheter aortic valve replacement: a systematic review and meta-analysis https://openheart.bmj.com/content/8/1/e001535#ref-9
Who Should Get to Be Called 'Doctor'? https://www.medscape.com/viewarticle/948887
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April 2, 2021 This Week in Cardiology
2 april 2021 · 18 min
COVID-19, long-COVID, the language of medicine, childhood obesity, and open notes are the topics covered by John Mandrola, MD, in this week's podcast. Lees meer
https://www.medscape.com/twic
COVID-19
AstraZeneca COVID Vaccine: Clotting Disorder Mechanism Revealed?
https://www.medscape.com/viewarticle/948560
Long COVID
Long COVID Brings Welcome Attention to POTS
https://www.medscape.com/viewarticle/948174
Keep Both 'Renal' and 'Nephro' in Glossary of Kidney Disease
https://www.medscape.com/viewarticle/948451
'Striking' Increase in Childhood Obesity During Pandemic
https://www.medscape.com/viewarticle/948350
COVID-19 and Changes in Child Obesity. https://pediatrics.aappublications.org/content/early/2021/03/01/peds.2021-050123
Starting Monday, Patients Can Read Your Notes:
5 Key Things https://www.medscape.com/viewarticle/948508
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https://www.medscape.com/author/bob-harrington
Questions or feedback, please contact
news@medscape.net
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Mar 26, 2021 This Week in Cardiology Podcast
26 maart 2021 · 19 min
COVID-19, AF detection post stroke, new measures of heart function, and structural racism in quality measures are the topics covered by John Mandrola, MD, in this week's podcast. https://www.medscape.com/twic Lees meer
COVID-19
NIH Rebukes AstraZeneca Vaccine Interim Data: 'Incomplete' https://www.medscape.com/viewarticle/947954
Neutralizing Antibodies Against SARS-CoV-2 Variants After Infection and Vaccination https://jamanetwork.com/journals/jama/fullarticle/2777898
AF and Stroke
Insertable Cardiac Monitors Improve AF Detection After Stroke https://www.medscape.com/viewarticle/947986
Perfection in LV Function Measurement
Adding Strain Measure to LVEF Better Predicts Later HF https://www.medscape.com/viewarticle/948114
Association of Left Ventricular Systolic Function With Incident Heart Failure in Late Life https://jamanetwork.com/journals/jamacardiology/fullarticle/2777414
Is the Left Ventricular Ejection Fraction Measurement Still Preeminent?—New Measures to Quantify Subclinical Systolic Dysfunction https://jamanetwork.com/journals/jamacardiology/fullarticle/2777412
Structural Racism in Pay for Performance
Association Between the Proportion of Black Patients Cared for at Hospitals and Financial Penalties Under Value-Based Payment Programs https://jamanetwork.com/journals/jama/fullarticle/2777701
Twitter Thread from Rishi Wadhera https://twitter.com/rkwadhera/status/1374380385560186883
References:
Sowell, Thomas A Conflict of Visions https://en.wikipedia.org/wiki/A_Conflict_of_Visions
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Mar 19, 2021 This Week in Cardiology Podcast
19 maart 2021 · 18 min
COVID-19, Fish Oil and AF risk, SGLT2 inhibitors and renal outcomes, and TAVR vs SAVR are the topics discussed by John Mandrola, MD, in this week's podcast. https://www.medscape.com/twic Lees meer
COVID-19
EMA Launches Review of Clot Risk With AstraZeneca COVID Vaccine https://www.medscape.com/viewarticle/947393
AZ Vaccine Safe Overall but Questions Remain over Unusual Clots https://www.medscape.com/viewarticle/947733
Fish Oil and AF
Dose-Related AF Risk With Omega-3 Fatty Acids? https://www.medscape.com/viewarticle/947542
Effect of Marine Omega-3 Fatty Acid and Vitamin D Supplementation on Incident Atrial Fibrillation https://jamanetwork.com/journals/jama/fullarticle/2777469
Omega-3 Fatty Acids and Atrial Fibrillation https://jamanetwork.com/journals/jama/fullarticle/2777450
SGLT2i and Renal Outcomes
Ertugliflozin: Renal Benefits in Additional VERTIS CV Analyses https://www.medscape.com/viewarticle/947668
Cardiovascular Outcomes with Ertugliflozin in Type 2 Diabetes https://www.nejm.org/doi/full/10.1056/NEJMoa2004967
Effects of ertugliflozin on kidney composite outcomes, renal function and albuminuria in patients with type 2 diabetes mellitus: an analysis from the randomised VERTIS CV trial https://link.springer.com/article/10.1007/s00125-021-05407-5
TAVR vs SAVR
TAVR vs SAVR in Low-Risk Patients: What We Do and Don't Know https://www.medscape.com/viewarticle/946173
Mortality in trials on transcatheter aortic valve implantation versus surgical aortic valve replacement: a pooled meta-analysis of Kaplan-Meier-derived individual patient data https://pubmed.ncbi.nlm.nih.gov/32236543/
Outcomes 2 Years After Transcatheter Aortic Valve Replacement in Patients at Low Surgical Risk https://www.jacc.org/doi/full/10.1016/j.jacc.2020.12.052
Five-Year Outcomes of Transcatheter or Surgical Aortic-Valve Replacement https://www.nejm.org/doi/full/10.1056/NEJMoa1910555
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March 12, 2021 This Week in Cardiology Podcast
12 maart 2021 · 21 min
COVID-19, heart failure classifications, DOAC after bioprosthetic valves, and Medicare spending in the pandemic year Are the topics discussed by John Mandrola, MD, in this week's podcast. https://www.medscape.com/twic Lees meer
I. COVID-19 Vaccination in Israel
COVID-19 Vaccination Linked to Less Mechanical Ventilation https://www.medscape.com/viewarticle/946568
BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Mass Vaccination Setting https://www.nejm.org/doi/full/10.1056/NEJMoa2101765
II. Heart Failure Classification
Heart Failure Redefined With New Classifications, Staging https://www.medscape.com/viewarticle/947048
Universal Definition and Classification of Heart Failure: A Report of the Heart Failure Society of America, Heart Failure Association of the European Society of Cardiology, Japanese Heart Failure Society and Writing Committee of the Universal Definition of Heart Failure https://doi.org/10.1016/j.cardfail.2021.01.022
Angiotensin–Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction https://www.nejm.org/doi/full/10.1056/NEJMoa1908655
Sacubitril/Valsartan Across the Spectrum of Ejection Fraction in Heart Failure https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.119.044586
III. DOACs In Bioprosthetic Valves --
DOACs Offered After Heart Valve Surgery Despite Absence of Data https://www.medscape.com/viewarticle/947193
Off-label Use of Direct Oral Anticoagulants in Patients Receiving Surgical Mechanical and Bioprosthetic Heart Valves https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2777141
Dabigatran versus Warfarin in Patients with Mechanical Heart Valves https://www.nejm.org/doi/full/10.1056/nejmoa1300615
2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: https://www.ahajournals.org/doi/10.1161/CIR.0000000000000665
Antithrombotic therapy in atrial fibrillation associated with valvular heart disease: a joint consensus document.... https://academic.ou…
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March 5, 2021 This Week in Cardiology Podcast
5 maart 2021 · 18 min
Cardiac studies in professional athletes after COVID-19 infection, percutaneous valve repair, AF screening, and social media are the topics discussed by John Mandrola, MD, in this week's podcast. To read a partial transcript or to comment https://www.medscape.com/twic Lees meer
COVID and the Athletic Heart
Incidence of Cardiac Pathology Post-COVID in Pro Athletes
Prevalence of Inflammatory Heart Disease Among Professional Athletes With Prior COVID-19 Infection Who Received Systematic Return-to-Play Cardiac Screening https://jamanetwork.com/journals/jamacardiology/fullarticle/2777308
Percutaneous Valve Repair
Delirium Common, Costly After Mitral, Tricuspid Valve Repair https://www.medscape.com/viewarticle/946736
Prevalence and Impact of Post-Procedural Delirium After Percutaneous Repair of Mitral and Tricuspid Valves https://www.jacc.org/doi/full/10.1016/j.jcin.2020.11.031
AF Screening
AF Screening in Asymptomatic Older Individuals Shows Promise https://www.medscape.com/viewarticle/946844
Screening for Atrial Fibrillation in the Older Population A Randomized Clinical Trial https://jamanetwork.com/journals/jamacardiology/fullarticle/2776728
Social Media
JAMA Podcast on Racism in Medicine Faces Backlash https://www.webmd.com/sex-relationships/news/20210304/jama-podcast-on-racism-in-medicine-faces-backlash
Time's Up Founder Choo Accused in Harassment Mishandling https://www.medscape.com/viewarticle/946678
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Feb 26, 2021 This Week in Cardiology Podcast
26 februari 2021 · 20 min
Risk factors for COVID-19, CMR after COVID-19, and two important obesity studies are discussed in this week's podcast. To read a partial transcript or to comment https://www.medscape.com/twic Lees meer
Cardiometabolic Conditions and COVID19
Most Severe COVID Tied to Four Cardiometabolic Conditions https://www.medscape.com/viewarticle/946488
Coronavirus Disease 2019 Hospitalizations Attributable to Cardiometabolic Conditions in the United States: A Comparative Risk Assessment Analysis https://www.ahajournals.org/doi/10.1161/JAHA.120.019259
CMR after COVID19
Myocardial Injury Seen on MRI in 54% of Recovered COVID https://www.medscape.com/viewarticle/946287
Patterns of myocardial injury in recovered troponin-positive COVID-19 patients assessed by cardiovascular magnetic resonance https://doi.org/10.1093/eurheartj/ehab075
Obesity Trials
Semaglutide for Weight Loss? A Good First STEP, With Caveats https://www.medscape.com/viewarticle/945630
Once-Weekly Semaglutide in Adults with Overweight or Obesity https://www.nejm.org/doi/full/10.1056/NEJMoa2032183
Major Breakthrough in Weight Loss With Semaglutide? https://www.medscape.com/viewarticle/940841
Effect of Subcutaneous Semaglutide vs Placebo as an Adjunct to Intensive Behavioral Therapy on Body Weight in Adults With Overweight or Obesity https://jamanetwork.com/journals/jama/fullarticle/2777025
Features
Fired for Good Judgment a Sign of Physicians' Lost Respect https://www.medscape.com/viewarticle/946286
A Tribute to Bernard Lown https://www.medscape.com/viewarticle/946447
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Feb 19, 2021 This Week in Cardiology Podcast
19 februari 2021 · 20 min
Bernard Lown, Type 2 MI, Sacubitril/Valsartan and COVID19 anticoagulation are discussed in this week's podcast. To read a partial transcript or to comment https://www.medscape.com/twic Lees meer
COVID
Israeli Study Finds Pfizer Vaccine 95% Effective Against COVID-19 https://www.medscape.com/viewarticle/945962
Bernard Lown
Cardiologist, Antiwar Activist Bernard Lown Dies at 99 https://www.medscape.com/viewarticle/945966
Type 2 MI
New Light Cast on Type-2 MI Aims to Sharpen Diagnosis, Therapy https://www.medscape.com/viewarticle/946075
Early AC in COVID19
More Evidence Supports Early Anticoagulation in COVID-19 https://www.medscape.com/viewarticle/945902
Sacubitril/Valsartan
FDA Expands Sacubitril/Valsartan Indication to Embrace Some HFpEF https://www.medscape.com/viewarticle/945936
Five Reasons Sacubitril/Valsartan Should NOT Be Approved for HFpEF https://www.medscape.com/viewarticle/944168
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Feb 12, 2021 This Week in Cardiology Podcast
12 februari 2021 · 20 min
Prediabetes, AI and ECGs, HFpEF, and observational studies are the topics discussed by John Mandrola, MD in this week's podcast. To read a partial transcript or to comment http://www.medscape.com/twic Lees meer
Pre-diabetes
'Prediabetes' Unlikely to Progress to Diabetes in Older Adults https://www.medscape.com/viewarticle/945511
Mobile QT Interval Measurement
Using AI, Mobile ECG Aims to Expand QTc Screening Horizons https://www.medscape.com/viewarticle/945484 Giudicessi JR et al.
Artificial Intelligence-Enabled Assessment of the Heart Rate Corrected QT Interval Using a Mobile Electrocardiogram Device | Circulation (ahajournals.org) https://www.ahajournals.org/doi/suppl/10.1161/CIRCULATIONAHA.120.050231
HFpEF
Exercise Quandary in HFpEF: Training Regimens Fall Short in Trial https://www.medscape.com/viewarticle/945621
Observational Study Follies
Statins Linked to Reduced Postop Adhesions, Bowel Obstruction https://www.medscape.com/viewarticle/945686
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Questions or feedback, please contact news@medscape.net
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Feb 5, 2021 This Week in Cardiology Podcast
5 februari 2021 · 21 min
Carotid screening, AF and alcohol, subcutaneous ICD, and medical education are the topics discussed by John Mandrola, MD, in this week's podcast. To read a partial transcript or to comment http://www.medscape.com/twic Lees meer
Carotid Screening
USPSTF Again Recommends Against Carotid Stenosis Screening https://www.medscape.com/viewarticle/945202
Subcutaneous ICD Recall
FDA Recalls Subcutaneous-ICD Leads Due to Fracture Risk https://www.medscape.com/viewarticle/945168
Alcohol and AF
Alcohol and the Electric Atrium, Part 2: When BAC Exceeds the Legal Limit https://www.medscape.com/viewarticle/945297
Medical Education
USMLE Stuns Again: Clinical Skills Test Permanently Ended https://www.medscape.com/viewarticle/944756
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Questions or feedback, please contact news@medscape.net
Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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Jan 29, 2021 This Week in Cardiology Podcast
29 januari 2021 · 19 min
AF and COVID-19, microthrombi in COVID-19 autopsies, vericiguat, and POTS are the topics covered by John Mandrola, MD, in this week's podcast. To read a partial transcript or to comment: http://www.medscape.com/twic Lees meer
AF and COVID
AF at COVID-19 Admission Predicts Mortality, Demands Vigilance https://www.medscape.com/viewarticle/944802
Microthrombi and COVID
Microthrombi, Necrosis Seen in COVID-19 Hearts on Autopsy https://www.medscape.com/viewarticle/944783
Vericiguat
FDA Approval Adds Vericiguat (Verquvo) to HF Treatment Options https://www.medscape.com/viewarticle/944434
POTS:
Lower-Body Compression Trims Orthostatic Tachycardia in POTS https://www.medscape.com/viewarticle/944791
Postural Orthostatic Tachycardia Syndrome (POTS): A critical assessment https://doi.org/10.1016/j.pcad.2020.03.010
Canadian Cardiovascular Society Position Statement on Postural Orthostatic Tachycardia Syndrome (POTS) and Related Disorders of Chronic Orthostatic Intolerance https://www.onlinecjc.ca/article/S0828-282X(19)31550-8/fulltext#secsectitle0130
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https://www.medscape.com/author/bob-harrington
Questions or feedback, please contact news@medscape.net
Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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Jan 22, 2021 This Week in Cardiology Podcast
22 januari 2021 · 21 min
COVID myocarditis, the Polypill, low-value care, and edge-to-edge tricuspid valve repair are discussed by John Mandrola, MD, in this week's podcast. Lees meer
Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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Jan 15, 2021 This Week in Cardiology Podcast
15 januari 2021 · 18 min
COVID, ACE/ARBs, left atrial appendage closure, SGLT2 inhibitors, and a clue in AF mechanisms are the topics discussed by John Mandrola, MD, in this week's podcast. Lees meer
Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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Jan 8, 2021 This Week in Cardiology Podcast
8 januari 2021 · 20 min
COVID vaccine schedules, trial translation, valve guidelines, and physician harassment on social media are the topics discussed by John Mandrola, MD, in this week's podcast. Lees meer
Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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Dec 18, 2020 This Week in Cardiology Podcast
18 december 2020 · 22 min
COVID, sacubitril/valsartan and spironolactone in patients with HFpEF, year-end comments are the topics discussed by John Mandrola, MD in this week's podcast. Lees meer
Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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Dec 11, 2020 This Week in Cardiology Podcast
11 december 2020 · 19 min
COVID, the clogged pipe frame of CAD, paclitaxel, and AF performance measures and Goodhart's law are the topics John Mandrola, MD, covers in this week's podcast. Lees meer
Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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Dec 4, 2020 This Week in Cardiology Podcast
4 december 2020 · 23 min
COVID vaccines, tocilizumab, finerenone, type 2 MI care, coronary CTA, and sotagliflozin are the topics discussed by John Mandrola, MD, in this week's podcast. Lees meer
Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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Nov 20, 2020 This Week in Cardiology Podcast
20 november 2020 · 21 min
COVID-19 vaccines and virtual AHA presentations on statins and the nocebo effect, high dose omega-3s, and AF ablation are the topics John Mandrola, MD, discusses on this week's podcast. Lees meer
Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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Nov 13, 2020 This Week in Cardiology Podcast
13 november 2020 · 20 min
COVID19 vaccines, thrombolysis in stroke, industry payments to doctors, and the upcoming AHA are topics covered by John Mandrola, MD, in this week's podcast. Lees meer
Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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Nov 6, 2020 This Week in Cardiology Podcast
6 november 2020 · 20 min
COVID, AF ablation, pediatric "do not dos" from AAP, heart failure performance measures, and a brief AHA preview are the topics discussed by John Mandrola, MD on this week's podcast. Lees meer
Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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Oct 30, 2020 This Week in Cardiology Podcast
30 oktober 2020 · 20 min
Remdesivir, the athletic heart, troponin and echo abnormalities in patients with COVID-19, and a novel MRA drug are the topics John Mandrola, MD, discusses in this week's podcast Lees meer
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Oct 23, 2020 This Week in Cardiology Podcast
23 oktober 2020 · 22 min
COVID, tocilizumab, hypertrophic cardiomyopathy, cerebral microbleeds, and surrogate endpoints are the topics discussed by John Mandrola, MD, in this week's podcast Lees meer
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Oct 16, 2020 This Week in Cardiology Podcast
16 oktober 2020 · 19 min
COVID drug trials and science news, BNP, polypharmacy in heart failure, and in-patient CPR are the topics john Mandrola, MD, discusses in this week's podcast Lees meer
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Oct 9, 2020 This Week in Cardiology Podcast
9 oktober 2020 · 17 min
COVID-19, scientific philosophy, left main coronary artery disease, empagliflozin and the SGLT2 inhibitors are the topics discussed by John Mandrola, MD in this week's podcast Lees meer
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Oct 2, 2020 This Week in Cardiology Podcast
2 oktober 2020 · 17 min
Scientific trust, publishing incentives, and the EXCEL trial, Vitamin D and COVID, and time-restricted eating are discussed by John Mandrola, MD, in this week's podcast. Lees meer
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Sep 25, 2020 This Week in Cardiology Podcast
25 september 2020 · 20 min
COVID sport participation guidelines, beta-blockers after MI, and low-dose DOAC therapy in AF are the topics covered by John Mandrola, MD, in this week's podcast. Lees meer
Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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Sep 18, 2020 This Week in Cardiology Podcast
18 september 2020 · 20 min
COVID, CMR after COVID, ISCHEMIA trial substudy, valvular heart disease and AF are the topics John Mandrola, MD, discusses in this week's podcast. Lees meer
Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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Sep 11, 2020 This Week in Cardiology Podcast
11 september 2020 · 19 min
COVID, icosapent ethyl, sudden death, and antiplatelet choices in the elderly are topics John Mandrola, MD, discusses in this week's podcast. Lees meer
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Sep 4, 2020 This Week in Cardiology Podcast
4 september 2020 · 21 min
COVID, trust in the FDA, and ESC Recap: Part 1 are the topics John Mandrola, MD, covers in this week's podcast. Lees meer
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Aug 28, 2020 This Week in Cardiology Podcast
28 augustus 2020 · 19 min
COVID and the heart, convalescent plasma, PCI in the VA system, and the upcoming ESC meeting are discussed by John Mandrola, MD, in this week's podcast. Lees meer
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Aug 21, 2020 This Week in Cardiology Podcast
21 augustus 2020 · 17 min
COVID, diversity, clinical research, the S-ICD, and ECGs are the topics discussed by John Mandrola, MD in this week's podcast. Lees meer
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Aug 14, 2020 This Week in Cardiology Podcast
14 augustus 2020 · 18 min
COVID, obesity, heart failure, Impella, and fitness are the topics John Mandrola, MD, discusses in this week's podcast. Lees meer
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Jul 31, 2020 This Week in Cardiology Podcast
31 juli 2020 · 16 min
COVID, cardiac effects of COVID, AF ablation safety, and SGLT2i are the topics discussed by Dr John Mandrola in this week's podcast. Lees meer
Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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Jul 24, 2020 This Week in Cardiology Podcast
24 juli 2020 · 17 min
COVID vaccines, T-cells, ICDs, Watchman, and two features are the topics John Mandrola, MD, discusses in this week's podcast. Lees meer
Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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Jul 17, 2020 This Week in Cardiology Podcast
17 juli 2020 · 20 min
COVID, the EXCEL trial, AF ablation, and pacemaker techniques are the topics discussed by John Mandrola, MD in this week's podcast. Lees meer
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Jul 10, 2020 This Week in Cardiology Podcast
10 juli 2020 · 19 min
COVID, sacubitril/valsartan, left atrial appendage occlusion, and statins are the topics Dr John Mandrola discusses in this week's podcast. Lees meer
Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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June 26, 2020 This Week in Cardiology Podcast
26 juni 2020 · 17 min
COVID, science communication breakthrough, tricuspid valve disease, and AF ablation are the topics discussed by John Mandrola, MD, in this week's podcast. Lees meer
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Jun 19, 2020 This Week in Cardiology Podcast
19 juni 2020 · 19 min
COVID19, corticosteroids, CAC, SGLT2i, and vericiguat are the topics discussed by Dr. John Mandrola in this week's podcast. Lees meer
Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.