Alle afleveringen
367 afleveringen, van nieuw naar oud
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266: Bacteria That Can Record
3 juni 2022 · 52 min
TWiM explains how spindle-shaped Archaeal viruses evolved from rod-shaped ancestors to package a larger genome, and transcriptional recording by CRISPR acquisition from RNA. Lees meer
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Links for this episode
From rods to spindles (Cell)
Spindle-shaped virus movie (Cell)
Bacteria that record (Science)
Transcriptional recording with CRISPR (Nature)
Letters read on TWiM 266
TWiM Listener survey
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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256: Antiviral Hotspots and Desiccation Tolerance
21 mei 2022 · 57 min
TWiM explains the discovery of hotspots of genetic variation containing reservoirs of anti-phage systems in E. coli phages and their parasitic satellites, and pathogen desiccation tolerance promoted by hydrophilins. Lees meer
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Links for this episode
Phage and satellite antiviral systems (Cell Host Micro)
Hydropilins promote desiccation tolerance (Cell Host Micro)
Letters read on TWiM 265
TWiM Listener survey
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv
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264: Antimicrobial Antipsychotics
6 mei 2022 · 1 uur 6 min
TWiM reveals that the atypical antipsychotic quetiapine promotes multiple antibiotic resistance in E. coli, and treatment with Bifidobacterium lactis probiotic benefits patients with coronary artery disease. Lees meer
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Links for this episode:
Antipsychotic promotes antimicrobial resistance (J Bact)
Probiotic benefits patients with coronary artery disease (mSystems)
B. lactis and Alzheimer's in mice (Eur J Nutr)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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263: Lavender and Catheters
16 april 2022 · 1 uur 3 min
TWiM explains the use of lavender oil to disrupt Listeria biofilms, and how treatment of catheters with liquid silicone reduces associated urinary tract infections. Lees meer
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Links for this episode
Lavender oil prevents biofilms (Lett Appl Micro)
Silicone-infused catheters reduce infection (eLife)
Viable but not culturable (TWiM 179)
Letters read on TWiM 263
TWiM Listener survey
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv
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262: Spot on With T4SS Modulators
1 april 2022 · 58 min
TWiM welcomes new host Petra, and explains how a small protein helps ensure that E. coli utilizes a preferred carbon source, and a screening strategy to identify inhibitors of the type IV secretion system that is essential for virulence of a variety of bacterial pathogens. Lees meer
Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson, and Petra Levin
Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Stitcher, Android, RSS, or by email.
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Links for this episode:
A small protein regulates carbon utilization (PNAS)
Inhibitors of type IV secretion systems (mBio)
Letters read on TWiM 262
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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261: Overwhelming Microbial Greatness
18 maart 2022 · 1 uur 20 min
Mark returns to TWiM to join in a discussion of soil microbiota as game-changers in restoration of degraded lands, and discovery of a centimeter-long bacterium, the biggest yet discovered. Lees meer
Guest: Mark O. Martin
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Links for this episode:
Game-changing soil microbiota (Science)
A World Without Soil by Jo Handlesman
A World Without Soil video (YouTube)
Centimeter-long bacteria (bioRxiv)
How large can a bacteria get? (YouTube)
Giant bacteria (YouTube)
Three faces of Thiomargarita (Small Things Considered)
The microbe that could be seen (Small Things Considered)
Energetics of the eukaryotic edge (Small Things Considered)
A lakeside tale (Small Things Considered)
Letters read on TWiM 261
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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260: Carnivorous Vulture Bees
25 februari 2022 · 44 min
In this food-centric TWiM, we reveal the microbiomes of carnivorous vulture bees and of Gala apples from all over the world. Lees meer
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Links for this episode
Microbiome of vulture bees (mBio)
Bees previously in TWiM 245
Microbiome of Gala apples (Envir Micro)
Apple flower microbiome (mBio)
TWiM Listener survey
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv
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259: Sea Sawdust
14 februari 2022 · 1 uur 2 min
Mark Martin returns to TWiM for a discussion of the frightening global burden of bacterial antibiotic resistance, and a solution to the problem of daylight nitrogen fixation in a cyanobacterium, despite the incompatibility of nitrogenase with oxygen produced during photosynthesis. Lees meer
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Links for this episode:
Global bacterial antimicrobial resistance (Nat Micro)
Cancer moon shot (NCI)
When antibiotics don't work (TED)
Cyanobacterium buoyancy (Nat Micro)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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258: A Tick's Meal
21 januari 2022 · 53 min
TWiM explains how bacterial symbionts regulate tick blood feeding activity, and the reasons why antibiotics exist. Lees meer
Hosts: Vincent Racaniello, Elio Schaechter, and Michael Schmidt
Subscribe to TWiM (free) on iTunes, Google Podcasts, Stitcher, Android, RSS, or by email.
Become a Patron of TWiM!
Links for this episode:
Symbionts help ticks to feed (Cell Host Microbe)
Why do antibiotics exist? (mBio)
Shorter is still better (J Hosp Med)
Shorter vs longer antibiotic courses (J Hosp Med)
Francis Tally and tigecycline (Clin Inf Dis)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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257: I have one word for you: plastics
7 januari 2022 · 1 uur 1 min
On this episode of TWiM, how phages prevent other phages from invading their hosts without blocking their own reproduction, and plastic-degrading potential of microbes across the Earth. Lees meer
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Links for this episode:
Prophages encode phage-defense systems with cognate self-immunity (Cell Host Microbe)
Prophages self-destruct to eliminate competitors (Cell Host Microbe)
Plastic-degrading potential across global microbiome (mBio)
Plastics in our foods (ENV media)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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256: An mRNA Vaccine Against Ticks
16 december 2021 · 42 min
TWiM discusses antigenic variation within dengue virus serotypes, and an mRNA vaccine that induces antibodies against tick proteins and prevents transmission of the Lyme disease agent. Lees meer
Hosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt and Michele Swanson
Subscribe to TWiM (free) on iTunes, Google Podcasts, Stitcher, Android, RSS, or by email.
Links for this episode:
Dengue virus antigenic variation (eLife)
mRNA vaccine induces tick resistance (Sci Transl Med)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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255: Fleaing The Plague
21 november 2021 · 53 min
TWiM reveals a study showing that positive interactions among bacteria are far more common than previously thought, and how acquisition of a single gene enabled Yersinia pestis to expand the range of mammalian hosts that sustain flea-borne plague. Lees meer
Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson, and Michael Schmidt
Subscribe to TWiM (free) on iTunes, Google Podcasts, Stitcher, Android, RSS, or by email.
Become a Patron of TWiM!
Links for this episode:
Positive interactions are common among bacteria (Sci Adv)
Expansion of mammal hosts for flea-borne plague (PLoS Path)
Hurling fleas (TWiM #80)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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254: Episymbionts Are Good For You
6 november 2021 · 1 uur 10 min
Mark Martin returns to TWiM for a discussion of the observation that Gram's stain does not cross the bacterial cytoplasmic membrane, and suppression of gingival inflammation and bone loss through host modulation caused by episymbiotic Saccharibacteria. Lees meer
Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson, and Michael Schmidt
Guest: Mark O. Martin
Subscribe to TWiM (free) on iTunes, Google Podcasts, Stitcher, Android, RSS, or by email.
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Links for this episode
Gram's stain does not cross cytoplasmic membrane (ACS Chem Biol)
Gram stain protocol (pdf)
Chemical mechanism of Gram's stain (J Bact)
Episymbiotic Saccharibacteria suppress disease (Host Cell Microbe)
Microedu listserve
TWiM Listener survey
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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253: Cell growth and cell size with Petra Levin
28 oktober 2021 · 1 uur 3 min
Petra Levin joins TWiM to tell three stories from her laboratory: how starvation induces shrinkage of the bacterial cytoplasm; plasticity of E. coli cell wall and how it influences antibiotic resistance across different environments; and induction of antibiotic resistance by Triclosan. Lees meer
Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson, and Michael Schmidt
Guest: Petra Levin
Become a Patron of TWiM!
Links for this episode
Starvation induces E. coli shrinkage (PNAS)
Plasticity of cell wall metabolism and antibiotic resistance (eLife)
Triclosan induces antibiotic resistance (Antimicro Agents Chemother)
TWiM Listener survey
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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252: Electrifying microbial fuel cells
8 oktober 2021 · 58 min
On this episode of TWiM, using colicins to ferry DNA into cells through an iron transporter, and construction of highly efficient microbial fuel cells that produce more electrical current than previously observed. Lees meer
Links for this episode:
Colicins used to ferry DNA into cells (mBio)
Highly efficient microbial fuel cells (Science)
Silver assists fuel cells (Science)
Biological transport goes the extra mile (PNAS)
Long distance transport in cable bacteria (PNAS)
Columbia U pledges fossil free buildings (Columbia U)
Become a patron of TWiM.
Send your microbiology questions and comments to twim@microbe.tv
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251: Biofilms, Coronaviruses, and a Shigella Vaccine
2 oktober 2021 · 57 min
TWiM explores the role of biofilms in infection by coronaviruses, and development of a Shigella vaccine using outer membrane vesicles derived from Salmonella Lees meer
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Links for this episode
Biofilms and coronaviruses (Appl Envir Micro)
Outer membrane vesicle vaccine (Appl Envir Micro)
TWiM Listener survey
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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250: E-scaffolds and paper stickers
10 september 2021 · 1 uur 5 min
On this episode, an electrochemical scaffold that delivers safe doses of hypochlorous acid to treat wound infections in humans, and a method for sampling and monitoring bacteria and viruses on surfaces using plain paper stickers. Lees meer
Hosts: Vincent Racaniello, Michele Swanson, and Michael Schmidt
Links:
E-scaffolds on TWiM 143
The EPS matrix (J Bact)
Integrated HOCL-producing E-scaffold (AAM)
Surface sampling bacteria with paper stickers (AEM)
Surface sample viruses with paper stickers (Sci Rep)
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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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249: Phage-pathogen and toxin-antitoxin conflicts
27 augustus 2021 · 49 min
TWiM reveals how temporal shifts in antibiotic resistance elements govern phage-pathogen conflicts, and the intracellular localization of toxin-antitoxin proteins in E. coli. Lees meer
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Links for this episode:
Phage-pathogen conflicts (Science)
A 'Trap-Door' Strategy for Mobile Element Escape (Front Micro)
Location of toxin-antitoxin proteins (mBio)
Babel-Jerusalem Bookstore
Letters read on TWiM 249
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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248: Borgs Are Real
13 augustus 2021 · 59 min
Mark Martin returns to TWiM to discuss ways to increase diversity in our field, and the discovery of Borgs, giant extrachromosomal elements with the potential to augment methane oxidation. Lees meer
Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson, and Michael Schmidt
Guest: Mark O. Martin
Subscribe to TWiM (free) on iTunes, Google Podcasts, Stitcher, Android, RSS, or by email.
Become a Patron of TWiM!
Links for this episode:
Unacknowledged privilege (Mol Biol Cell)
Black Microbiologists Association
Beginner's Guide to Minority Professor Hires
(ASM)Academic Career Readiness Assessment (UCSF)
Annual Biomed Res Conference for Minority Students
Lessons from Plants by Beronda Montgomery
Giant extrachromosomal BORGS (bioRxiv)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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247: Therapy With Paleofeces and Phages
30 juli 2021 · 55 min
TWiM explores whether 'rewilding' is a way to get back our missing gut microbes, and failure of bacteriophage therapy due to the production of neutralizing antibodies. Lees meer
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Links for this episode
Gut microbiota through an evolutionary lens (Science)
You're missing microbes (NY Times)
There is no 'healthy' microbiome (NY Times)
Antibody limits bacteriophage therapy (Nat)
Phage therapy on TWiEVO #44
Graham Hatfull on TWiV #87
TWiM Listener survey
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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246: Intracellular niche and passage
20 juli 2021 · 57 min
The TWiM folk explore disruption of a Burkholderia intracellular niche by a cell death program, and an increase in Brucella infectiousness after intracellular passage. Lees meer
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Links for this episode:
Disrupting intracellular niche (mBio)
Intracellular passage increases infectiousness (Infect Immun)
Type IV secretion systems (Front Micro)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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245: Bacteria that protect bees from fungi
3 juli 2021 · 50 min
In this episode, how polysaccharides keep cyanobacteria afloat in the oceans so that they can carry out photosynthesis, and a symbiotic bacterium that protects honey bees from fungal infections. Lees meer
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Links for this episode:
Bacterial blooms and polysaccharides (eLife)
Social life of cyanobacteria (eLife)
Bacteria that protect bees from fungi (mBio)
First 21 days of a bee's life (YouTube)
antiSMASH (Nucl Acids Res)
Delaney Miller's website
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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244: Chewing for chicha
22 juni 2021 · 57 min
Foodie TWiM reveals that bacteria in human saliva are major components of Ecuadorian indigenous beers, and an unusual E. coli that produces atypical light cream-colored colonies in chromogenic agar. Lees meer
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Links for this episode:
Saliva bacteria in indigenous beers (Peer J)
Unusual behavior of E. coli ST59 (Appl Envir Micro)
One Health (CDC)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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243: Beef and bacillus
5 juni 2021 · 52 min
TWiM continues its food arc with an examination of the effect of peroxyacetic acid spray on the microbiome and sensory properties of beef, and explores asymmetry of the cell division machinery during sporulation. Lees meer
Links for this episode:
Effect of peroxyacetic acid on beef (Appl Envir Micro)
Peracetic acid sterilization (CDC)
Different cuts of beef (S. Clyde Weaver)
Profiling the Poglianos (TWiM 115)
Cell division machinery asymmetry in sporulation (eLife)
Kamala Sohonie by Kanika Khanna
India COVID SOS
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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242: Sourdough Starter Microbiomes
21 mei 2021 · 54 min
TWiM reveals the microbiome of sourdough starter cultures, and discovery of a novel family of prokaryotic nanocompartments involved in the metabolism of sulfur. Lees meer
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Links for this episode
Sourdough starter microbiomes (eLife)
Prokaryotic nanocompartments (eLife)
TWiM Listener survey
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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241: What Does Flu Do to Your Poo?
7 mei 2021 · 1 uur 4 min
TWiM explains how Vibrio biofilms are dispersed by polyamine signals, and the induction of inappetence by respiratory virus infection which causes alteration of the gut microbiome. Lees meer
Subscribe to TWiM (free) on Apple Podcasts, Spotify, Google Podcasts, Android, RSS, or by email.
Become a patron of TWiM.
Links for this episode
Regulation of Vibrio biofilms by polyamines (eLife)
Cyclic di-GMP (pdf)
Respiratory virus infection induces inappetance (mBio)
Letters read on TWiM 241
TWiM Listener survey
Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv
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240: Aspirin, colorectal cancer, and Fusobacterium
26 april 2021 · 1 uur 1 min
TWiM reviews aspirin modulation of Fusobacterium nucleatum, a microbe that has been associated with colorectal cancer, and Elio tells us 'What are vaccines', a talk he recently gave to members of his community. Lees meer
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Links for this episode:
Elio's What are Vaccines? (pdf)
Jenner Museum
Aspirin modulation of Fusobacterium (mBio)
Fecal transplant for C. difficile (NEJM)
Fecal microbiota transplantation (NEJM)
Fecal microbiota transplant for dysbiosis (NEJM)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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239: The Phoenix of Bacteria
9 april 2021 · 54 min
The TWiM team reviews how variants of P. aeruginosa survive antimicrobial treatment, and a decrease in the antimicrobial resistance of the gut microbiome in the presence of the fungus C. albicans. Lees meer
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Links for this episode:
Phoenix colony variants of P. aeruginosa (AAC)
Candida and the gut microbiota (mSphere)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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238: Parkinson's disease gut microbiome
28 maart 2021 · 57 min
Elio reveals his thoughts on the big themes of modern microbiology, followed by an analysis of the gut microbiome in patients with Parkinson's disease. Lees meer
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Links for this episode:
Parkinson's disease gut microbiome (NPJ Parkinsons)
Sequencing data as compositions (Bioinformatics)
Gut microbiota in mouse Parkinson's model (Cell)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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237: Ten years of TWiM, a quality quorum
11 maart 2021 · 1 uur 5 min
To celebrate ten years, TWiM asks former hosts and guests to provide their thoughts on how microbiology has contributed to our understanding of the microbial world. Lees meer
Links for this episode:
Neisseria LINES up: TWiM #1
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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236: Gossamer wings and symbionts on the sea bottom
20 februari 2021 · 44 min
In this episode, hiring and training expectations for future biomedical life sciences faculty, and the roles of bacterial symbionts in deep-sea hydrothermal vent tubeworms. Lees meer
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Links for this episode:
Expectations for life sciences faculty (Life Sci Edu)
Academic career readiness assessment (UCSF)
Tubeworm bacterial symbionts (eLife)
Traveling on the Alvin (Dark Life II)
Image credit
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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235: Green algae and fatty acids
5 februari 2021 · 1 uur 5 min
In this episode, how DNA of giant viruses has contributed extensively to the genome of green algae, and inhibition of E. coli virulence by a metabolic product of arachidonic acid in the intestinal epithelium. Lees meer
Links for this episode:
Giant viral DNA shapes genomes of green algae (Nature)
James Van Etten
Darwin's Radio
Arachidonic acid and E. coli virulence (mBio)
How a pathogenic E. coli infection begins
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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234: Corkscrewing through snot
21 januari 2021 · 45 min
The TWiM team reviews Salmonella colonization of three-dimensional miniature intestinal organs, and identification of a circadian clock in a non-photosynthetic prokaryote. Lees meer
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Links for this episode:
Salmonella colonization of enteroids (mBio)
Circadian clock in nonphotosynthetic prokaryote (Science)
Image credit
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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233: Antivirals made by bacteria
8 januari 2021 · 53 min
The TWiM team reviews the movie Jezebel, played against the background of the yellow fever epidemic of 1853 in New Orleans, and prokaryotic viperins, ancestors of the eukaryotic enzymes that synthesize antiviral molecules. Lees meer
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Links for this episode
Jezebel (Wikipedia)
Prokaryotic viperins (Nature)
A cell protein that synthesizes antivirals (virology blog)
Dr. Aude Bernheim's training and gender equity contributions
TWiM Listener survey
Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv
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232: Microbial nanowires
24 december 2020 · 56 min
TWiM explores the use of a bacterial protein to make highly conductive microbial nanowires, and how modulin proteins seed the formation of amyloid, a key component of S. aureus biofilms. Lees meer
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Become a patron of TWiM.
Links for this episode
Amyloid formation for S. aureus biofilms (eLife)
Highly conductive microbial nanowires (Nat Chem Biol)
Uncovering Nature's electronics (Nature)
Activating Nature's electrical grid (Bioeng)
Bacteria that exhale electricity (SyFyWire)
Microbial transistors (TWiM 14)
TWiM Listener survey
Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv
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231: It's a microbe-eat-microbe world
11 december 2020 · 55 min
Mark Martin returns to TWiM for a discussion of a predatory bacterium appropriately named Vampirococcus lugosii, and Elio reveals how bacteria can be used on the International Space Station to efficiently extract rare earth elements in microgravity. Lees meer
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Links for this episode:
Space Station biomining (Nat Comm)
Reductive evolution in a predatory bacterium (bioRxiv)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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230: Ancient bacterial DNA
27 november 2020 · 56 min
In this episode of TWiM, control of Campylobacter in raw chicken by zinc oxide nanoparticles in packaging material, and Salmonella enterica genomes from a16th century epidemic in Mexico. Lees meer
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Links for this episode:
Zinc oxide nanoparticles in raw meat packing (Appl Env Micro)
Campylobacter, an emerging foodborne pathogen (Emerg Inf Dis)
Ancient bacterial DNA (Microb Genom)
Salmonella enterica from 16th century outbreak (Nature)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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229: Dirt is not simple
6 november 2020 · 50 min
In this episode of TWiM, the hidden biochemical diversity in soil-dwelling Actinobacteria that could lead to a second Golden Era of antibiotic discovery, and structures of glideosome components reveals the mechanism of gliding in apicomplexan parasites. Lees meer
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Links for this episode:
Cryptic or silent? (mBio)
The Streptomyces chromosome (Ann Rev Gen)
Engineering Nature's Medicines (pdf)
Apicomplexan glideosome (Comm Biol)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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228: Black in Microbiology with Ninecia Scott and Chelsey Spriggs
23 oktober 2020 · 53 min
Ninecia and Chelsey, two of the founders of Black in Microbiology, join TWiM to discuss the goals of the organization, then we reveal survival of Deinococcus bacteria for 3 years in space, an experiment that addresses the panspermia hypothesis for interplanetary transfer of life. Lees meer
Guests: Ninecia Scott and Chelsey Spriggs
You can watch this episode at https://youtu.be/1o1hh0I4rio
Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Android, RSS, or by email.
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Links for this episode
Black in Microbiology
Deinococcus DNA damage in space (Front Micro)
Monthly myco-talks (Uni Exeter)
Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv
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227: The light and dark sides of the fungal world
13 oktober 2020 · 48 min
TWiM presents an episode for mycophiles: how bacteria disarm mushroom pathogens, and the role of the CARD9 protein in protective immunity against pulmonary cryptococcosis. Lees meer
Hosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt and Michele Swanson
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Links for this episode:
Black in Microbiology
How bacteria disarm mushroom pathogens (PNAS)
A bacterial battleground (Science)
CARD9 needed for fungal defense (mBio)
OneHealth: Fungal pathogens (AAM)
Image credit
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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226: Two microbes you might not know
24 september 2020 · 1 uur 10 min
TWiM presents two unusual microorganisms, Erysipelothrix rhusiopathiae, heard by Elio in an episode of Doc Martin, and Roseomonas mucosa, which is being used to treat atopic dermatitis. Lees meer
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Links for this episode:
Erysipelothrix rhusiopathiae
Treating atopic dermatitis with R. mucosa (Sci Trans Med)
Overview of sphingolipid metabolism (Adv Exp Med Biol)
Lyme disease and other tick-borne infections (MTM 118)
Image credit
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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225: Lag phase is no slouch
11 september 2020 · 1 uur 3 min
The TWiM team explores how delivery of an enzyme into competitor cells leads to synthesis of (p)ppApp, depletion of ATP, deregulation of metabolic pathways, and cell death, and a refinement of our typical view of bacterial lag phase as a period of nonreplication. Lees meer
Hosts: Vincent Racaniello, Elio Schaechter, and Michael Schmidt
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Links for this episode:
Killing competitors by synthesis of (p)ppApp (Nature)
Lag phase is a dynamic period (J Bact)
Image credit
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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224: One hundred million year old bacteria
28 augustus 2020 · 1 uur 15 min
The TWiM team reveals the genetic mysteries of the Dead Sea Scrolls from sequencing of DNA, and 100 million year old living bacteria recovered from marine sediments. Lees meer
Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson and Michael Schmidt
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Links for this episode:
Elio's Memoirs
Genetic mysteries of Dead Sea Scrolls (Cell)
100 million year old bacteria under the sea (Nat Comm)
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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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223: The smell of soil
15 augustus 2020 · 1 uur 1 min
The TWiMmers explore detection of SARS-CoV-2 on surfaces in an ophthalmology examination room, the ability of stressed populations of Yersinia bacteria to survive antimicrobial treatment within host tissues, and how volatile organic chemicals produced by soil microbes attract arthropods which in turn disperse bacterial spores. Lees meer
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Links for this episode
SARS-CoV-2 RNA in ophthalmology room (JAMA Ophth)
Stressed Yersinia survive doxycycline treatment (mBio)
Volatiles, a soil arthropod, and Streptomyces spore dispersal (Nature)
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Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv
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222: Biosensors in bacteria
31 juli 2020 · 1 uur 19 min
Mark Martin joins TWiM to describe nano-sized parasitic bacteria that inhabit humans, and the construction of whole-cell biosensors for detecting arsenic in drinking water. Lees meer
Hosts: Vincent Racaniello, Elio Schaechter, and Michael Schmidt
Guest: Mark O. Martin
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Links for this episode
Ultra-small parasitic bacteria in humans (Cell Rep)
Arsenic (WHO)
Arsenic and drinking water (CDC)
Arsenic biosensor in bacteria (Appl Envir Micro)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv
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221: Weapon of mucus destruction, WMD
16 juli 2020 · 1 uur 9 min
TWiM reveals a potential mucus-busting weapon for patients with cystic fibrosis, and bacteria in the intestinal tract that can oxidize cholesterol, leading to lower levels of the lipid in blood. Lees meer
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Links for this episode
Biofilm eradication with nitric oxide release (ACS Inf Dis)
Pseudomonas quorum sensing network (Protein)
Cholesterol metabolism by gut bacteria (Cell Host Microbe)
Microbes might manage your cholesterol (Harvard Gazette)
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Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv
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220: From Mars to the vagina
3 juli 2020 · 43 min
TWiM reveals that methane-producing bacteria might survive beneath the surface of Mars, and identification of a cytopathogenic toxin in a bacterium associated with preterm birth. Lees meer
Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson and Michael Schmidt
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Links for this episode:
Archaea could make methane on Mars (Sci Rep)
Cytopathogenic toxin in bacterium associated with preterm birth (J Bact)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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219: Commensal for a healthy skin
19 juni 2020 · 1 uur 2 min
The TWiM discusses eradicating racism in academia and STEM, and a peptide from commensal bacteria that protects skin from damage caused by MRSA Lees meer
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Links for this episode:
Responsibility in academic research
Improving equity in faculty hiring (MBoC)
#ShutDownSTEM
Peptide protects skin from microbial damage (AAC)
Agr phase variants in S. aureus (mBio)
S. aureus quorum sensing system (BMC Res Notes)
COVID-19 joins pandemic legion (mBio)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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218: The lengths SARS-COV-2 will go
6 juni 2020 · 1 uur 2 min
The TWiM team explains how breathing can transmit SARS-CoV-2, and how lack of breathing leads to loss of mitochondria in a multicellular parasitic animal. Lees meer
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Links for this episode:
Reducing transmission of SARS-CoV-2 (Science)
Why social distancing is important (NY Times)
Parasite without mitochondria (PNAS)
Letters read on TWiM 218
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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217: The chronicles of narnaviruses
22 mei 2020 · 52 min
The TWiM team explains an experimental vaccine to prevent E. coli urinary tract infections, and the remarkable three-way symbiosis of narnaviruses, bacteria, and fungi. Lees meer
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Become a patron of TWiM.
Links for this episode
Developing a vaccine for UTI (mBio)
Narnaviruses and bacteria-fungal symbioses (ISME J)
20% off The Invisible ABCs for TWiM listeners! Use promo code: ABC20 at checkout.
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