Alle afleveringen
367 afleveringen, van nieuw naar oud
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216: It starts with a cough
1 mei 2020 · 1 uur 4 min
The TWiM team discuses saliva as more sensitive for SARS-CoV-2 detection in COVID-19 patients than nasopharyngeal swab and how Mycobacterium tuberculosis sulfolipid-1 activates nociceptive neurons and induces cough. Lees meer
Links for this episode:
Preventing the next pandemic (NY Times)
COVID-19 treatment guidelines (NIH)
Saliva sensitive for SARS-CoV-2 detection (medRxiv)
A mycobacterial molecule provokes cough (Cell)
Letters read on TWiM 216
20% off The Invisible ABCs for TWiM listeners! Use promo code: ABC20 at checkout.
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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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215: Cultural transformation and pathogen emergence
17 april 2020 · 57 min
A ferret model for infection by SARS-CoV-2, and how Neolithization lead to emergence of a human bacterial pathogen. Lees meer
Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson and Michael Schmidt
Links for this episode:
Infection and transmission of SARS-CoV-2 in ferrets (Cell Host Micr)
Neolithization led to emergence of Salmonella enterica (Nat Ecol Evol)
Arnold Demain (Wikipedia)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
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214: Masterful subversion
3 april 2020 · 59 min
Vincent, Elio and Michael reveal the ASM COVID-19 summit, and how Salmonella injects a protein into the cell to drive suppression of the immune response. Lees meer
ASM COVID-19 Summit
Value of SARS-CoV-2 diagnostic testing (mBio)
How SARS-CoV-2 is changing (nextstrain)
Contribute to COVID-19 data
Salmonella effector suppresses inflammation (Cell Host Micr)
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213: Fugitive emissions
20 maart 2020 · 1 uur 1 min
Vincent, Elio and Michael discuss the stability of human coronaviruses on surfaces and in aerosols, and peptidoglycan production by a mosaic consisting of a bacterium within a bacterium within an insect. Lees meer
Links for this episode:
Human coronavirus 229E infectivity on common surfaces (mBio)
Aerosol and surface stability of SARS-CoV-2 (medRxiv)
Peptidoglycan synthesis by a insect-bacteria mosaic (Cell)
Letters read on TWiM 213
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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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212: A coronavirus outbreak and IRF4 deficiency in Whipple's disease
6 februari 2020 · 55 min
The TWiM team reviews the coronavirus outbreak that began in Wuhan, China, and the finding that an IRF deficiency underlies Whipple's disease. Lees meer
2019-nCoV case tracking (JHU)
Clinical features of infection with 2019-nCoV (Lancet)
Early transmission dynamics of 2019-nCoV (NEJM)
Isolation of 2019-nCoV (NEJM)
TLR4 defect in Whipple's disease (eLife)
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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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211: Bacteria, colon cancer and fire blight
10 januari 2020 · 1 uur 18 min
The Fellowship of the TWiM reveal that colorectal cancer-associated microbiota are associated with higher numbers of methylated genes in colonic mucosa, and identification of metabolites needed by the fire blight disease bacterium for virulence in apples. Lees meer
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Links for this episode:
Colorectal cancer and the gut microbiome (PNAS)
Fire blight (YouTube)
Fire blight spreads north (NY Times)
E. amylovora auxotrophs (Appl Environ Micro)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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210: The Waze of microbes
5 december 2019 · 1 uur 16 min
The Microbial Comrades present the oldest osteosynthesis in history, and how a small molecule produced by stressed bacteria is a warning signal that repels healthy populations to promote their survival. Lees meer
Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson and Michael Schmidt
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Become a patron of TWiM.
Links for this episode
P. aeruginosa PQS repels bacteria(J Bact)
PQS signaling(J Bact)
Letters read on TWiM 210
TWiM Listener survey
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209: Resuscitating persisters and flagellotrophic phage
15 november 2019 · 58 min
The TWiM team reveals how ribosome modification resuscitates bacterial persister cells, and explain how a phage tail fiber protein exploits rotation of flagella to move towards the cell membrane. Lees meer
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Links for this episode:
Ribosome modification resuscitates persister cells (Environ Micro)
Flagellotrophic phage targets host with tail fiber (Mol Micro)
Hydrodynamics of phage migration along flagella (Phys Rev Fluids)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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208: Georgia Tech microbial
31 oktober 2019 · 1 uur 23 min
Hosts: Vincent Racaniello, Michele Swanson and Michael Schmidt Lees meer
Guests: Deanna Beatty, Mark Hay, Gina Lewin, Frank Stewart, and Marvin Whiteley
At Georgia Tech, members and trainees of the Center for Microbial Dynamics and Infection discuss the identification of pathogen essential genes during coinfections, and how coral management can improve coral defenses against pathogens.
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Links for this episode:
Center for Microbial Dynamics and Infection
Pathogen essential genes during coinfection (PNAS)
Managing coral protects from pathogens (Sci Adv)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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207: Partnerships to Advance Public Health
17 oktober 2019 · 1 uur 7 min
From ASM Microbe 2019 in San Francisco, Vincent speaks with Victoria McGovern, Carl Nathan, and Dan Portnoy about advancing human health through innovative collaborations. Lees meer
Host: Vincent Racaniello
Guests: Victoria McGovern, Carl Nathan, and Dan Portnoy
Links for this episode:
Getting grants (Virulence)
Nitric oxide synthase protects against tuberculosis (PNAS)
Actin filaments and Listeria monocytogenes (J Cell Biol)
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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
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206: Bacteria send nucleotide signals
3 oktober 2019 · 1 uur 5 min
The TWiM holobionts pay tribute to Stuart Levy, and reveal the remarkably diverse array of cyclic nucleotides synthesized by bacteria that likely mediate interactions with animal and plant hosts. Lees meer
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Links for this episode:
Stuart Levy, Antibiotic Resistance Researcher, Dies
Resistance fighter (The Scientist)
Stuart Levy on TWiM 16
Stuart Levy on Meet the Scientist episode 17
Segregation of R factors (Nature)
Infectious drug resistance (Sci Am)
Spread of antibiotic resistance chickens to humans (Nature)
Costs of antimicrobial resistance (Clin Inf Dis)
Bacteria synthesize diverse nucleotide signals (Nature)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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205: Asgards meet the Tardigrades
21 september 2019 · 1 uur 7 min
The tetracoccal TWiM team visits Tardigrades on the Moon, and the twelve year quest to isolate an archaeon that provides insights into the emergence of the first eukaryotic cell. Lees meer
Links for this episode:
Tardigrades on the moon (Mashable)
Meet the Tardigrade (WaPo)
Archaeon at prokaryote-eukaryote interface (bioRxiv)
Subscribe to TWiM (free) on iTunes, Google Podcasts, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.
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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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204: Programmable bacteria for antitumor immunity
6 september 2019 · 1 uur 8 min
Host: Vincent Racaniello Lees meer
Guests: Nicholas Arpaia and Tal Danino
Vincent meets up with Nick and Tal to explain how they engineered E. coli to lyse within tumors and deliver an antibody that causes tumor regression in mice.
Links for this episode:
Programmable bacteria induce tumor immunity (Nat Med)
Synchronized cycles of bacterial lysis (Nature)
TWiM Listener survey
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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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203: A magnetotactic consortium under the sea
22 augustus 2019 · 58 min
The TWiM team reveals thousands of small novel genes in the human microbiome, and a mutualistic symbiosis between marine protists covered with magnetosome-containing bacteria. Lees meer
Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson and Michael Schmidt
Links for this episode
Thousands of small novel genesin human microbiome (Cell)
A magnetotactic consortiumunder the sea (Nat Micro)
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Letters readon TWiM 203
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
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202: This frass doesn't stink
8 augustus 2019 · 1 uur 2 min
Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson and Michael Schmidt Lees meer
Guest: Julie Wolf
Julie joins the TWiM team to reveal how microbiome and gut anatomy of a wood-feeding beetle promotes lignocellulose deconstruction, and bacteria that degrade PET plastic.
How wood-feeding beetles deconstruct lignocellulose (PNAS)
Meet the Microbiologist hosted by Julie Wolf
Bacteria that degrade PET plastic (Micr Res Ann)
Microbiology resource of the month (ASM)
Morgan Vague's TED talk
Pacific garbage patch (Pacific Beach Coal)
NOAA marine debris program
National Geographic's Planet or Plastic Campaign
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Letters read on TWiM 202
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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
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201: Microbiology papers for first year students
27 juli 2019 · 1 uur 24 min
Mark Martin joins Vincent and Michael to present compelling papers suitable for teaching microbiology to undergraduate students. Lees meer
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Links for this episode:
Paradigm shifts, paradigm drifts (pdf)
Introducing THOR (mBio)
Engineering bacteriophages to treat mycobacterial infection (Nat Med)
Biofilms by Colter (Int Microbiol)
Life in a world without microbes (PLoS Biol)
Reduction of cholera in Bangladeshi villages (PNAS)
Placenta goes viral (PLoS Biol)
#OMG (jpg)
#OMG illustration by Sarah Adkins
Microbe-Biologist button (jpg)
Microbial Centricity button (jpg)
Microbial Eyes button (jpg)
Micronauts button (jpg)
Send your microbiology questions and comments to twim@microbe.tv
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
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200: In the company of Elio
12 juli 2019 · 1 uur 1 min
Vincent, Michele, and Michael travel to San Diego to reminisce with Elio about his career, his work in microbiology, and his love for microbes and mushrooms. Lees meer
VIDEO VERSION AVAILABLE: https://www.youtube.com/watch?v=Menlo1YvPko
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Links for this episode
Elio's profile
Elio's memoirs
Elio's first paper, 1952 (J Bact)
In the Company of Mushrooms
Small Things Considered
TWiM Listener survey
Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv
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199: PhD Balance
28 juni 2019 · 1 uur 15 min
From ASM Microbe 2019, the Microbials meet up with Susanna L. Harris and Alex Politis to talk about mental health in graduate school and NIH peer review. Lees meer
Hosts: Vincent Racaniello, Michele Swansonand Michael Schmidt
Guests: Susanna L. Harrisand Alex Politis
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Links for this episode
PhD Balance
Susanna's video(Vimeo)
NIH Center for Scientific Review
TWiM Listener survey
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198: Unexpectedly pathogenic bacteriophages
1 juni 2019 · 1 uur
The TWiM team presents an extracellular bacterium associated with Paramecium, and induction of antiviral immunity by a bacteriophage that prevents bacterial clearance. Lees meer
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Bacteria on the outside of paramecia (ISME)
Phage trigger antiviral immunity (Science)
Image credit
Letters read on TWiM 198
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
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197: Intercellular microbial trade
26 april 2019 · 1 uur 10 min
The Microbials reveal how a chemosynthetic symbiont stores energy for its marine flatworm host, and extraction of nutrients from host cells by E. coli injectisome components. Lees meer
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Links for this episode:
Take the TWiM listener survey
Bacteria store energy for gutless worms (PNAS)
Paracatenula on TWiM #21
E. coli extracts nutrients from host cells (Cell)
Image credit
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
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196: I hear you
29 maart 2019 · 1 uur 4 min
The Microbials discuss how ambrosia beetles utilize ethanol to farm fungi, and how cleaved cochlin protein sequesters bacteria in the inner ear to preserve hearing function. Lees meer
Links for this episode:
Ambrosia beetles, ethanol, and farmed fungi (PNAS)
Cleaved cochlin protects the inner ear (Cell Host Microbe)
Importance of flossing (ADA)
Subscribe to TWiM (free) on iTunes, Google Podcasts, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.
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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
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195: Gingipain in the Alzheimer brain
4 maart 2019 · 1 uur 15 min
Michael and Vincent discuss the finding of immunity to Cas9 protein in humans, and a potential role for an oral bacterium in Alzheimer's disease. Lees meer
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Links for this episode
Immunity to Cas9 protein in humans (Nat Med)
P. gingivalis and Alzheimer's disease (Science)
Clinical trial of COR388 in AD patients (clinicaltrials.gov)
TWiM Listener survey
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194: Standard imperial procedure
14 februari 2019 · 1 uur 5 min
Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter Lees meer
How a bacterium helps dengue virus replicate in the mosquito gut, and minicells as a damage disposal mechanism in E. coli.
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Links:
Please take the TWiM listener survey
Bacteria help dengue virus in mosquito gut (Cell Host Micr)
Fungus helps dengue virus in mosquito gut (TWiV 479)
Minicells for disposal of damaged goods (mSphere)
TWiM Listener survey
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193: Persisters
31 januari 2019 · 1 uur 1 min
The TWiM team explore how Lactobacillus reuteri can rescue social deficits in three mouse models of autism spectrum disorder, and the role of Salmonella persisters in undermining host defenses during antibiotic treatment. Lees meer
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Please take the
TWiM listener surveyBacteria alter behavior in mouse autism models (Neuron)
Mice behaving badly (TWiM 131)
Salmonella persisters undermine host immune defenses (Science)
Persister cells (Ann Rev Microbiol)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
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192: A Qtip for phages
18 januari 2019 · 1 uur 6 min
The TWiM team reveals an extremely low rate of mutation in a 2500 year old, 185 acre fungus in Michigan, and how a host-produced quorum sensing autoinducer controls the phage switch between lysis and lysogeny. Lees meer
Please take the TWiM listener survey
Vote for NJ State Microbe
Huge fungus is 2500 years old (Proc Roy Soc B)
Humongous fungus (Wikipedia)
Host-produced autoinducer controls phage (Cell)
These bacteria are bugged (virology blog)
Subscribe to TWiM (free) on iTunes, Google Podcasts, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.
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Links for this episode
Please take the TWiM listener survey
Vote for NJ State Microbe
Huge fungus is 2500 years old (Proc Roy Soc B)
Humongous fungus (Wikipedia)
Host-produced autoinducer controls phage (Cell)
These bacteria are bugged (virology blog)L
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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191: By the pulp of their teeth
22 december 2018 · 1 uur 2 min
The TWiM team reveals the oldest human plague from 4,900 years ago in Sweden, and engineering E. coli to become an endosymbiont in yeast, modeling the evolution of mitochondria. Lees meer
Hosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt, and Michele Swanson
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Links for this episode
Oldest human plague from 4,900 years ago (PNAS)
Engineering yeast endosymbionts (PNAS)
Letters read on TWiM 191
TWiM Listener survey
Send your microbiology questions and comments (email or recorded audio) to "mailto:twim@microbe.tv">twim@microbe.tv
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190: Exosomes in your nose and in your gut
7 december 2018 · 1 uur 19 min
The TWiM-opods consider two stories about exosomes, vesicles that are shed from cells: those that eliminate airway pathogens, and those from the plants we eat that shape our gut microbiome. Lees meer
Hosts:
Vincent Racaniello, Michael Schmidt, and Michele Swanson.
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Links for this episode
Exosome swarms eliminate airway pathogens (J Aller Clin Immunol)
Exosome release from Bacteria, Eukaryotes, Archaea (Infect Immun)
Plant exosomes shape gut microbiome (Cell Host Microbe)
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189: Salmonella BonJovi
16 november 2018 · 1 uur 11 min
The TWiM team considers the state of the world's fungi as revealed by a report from the Kew Royal Botanical Gardens, and how Salmonella loses motility to evade host defenses. Lees meer
Hosts: Vincent Racaniello, Michael Schmidt, Elio Schaechter, and Michele Swanson
Take our listener survey. Thanks! asm.org/twimpoll
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Links for this episode:
Subscribe to MicrobeTV on YouTube
State of the World's Fungi 2018
Salmonella loses motility to avoid inflammasome activation (Cell Rep)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
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188: Turducken antibiotics
31 oktober 2018 · 1 uur 21 min
The TWiM rock stars show how to modify gram-positive antibiotics so they can kill gram-negative cells, and bacteria that have both DNA and RNA in their genome. Lees meer
Hosts: Vincent Racaniello and Michael Schmidt
Links for this episode
Antibiotics for gram-positives that kill gram-negatives (J Med Chem)
Sideromycin commentary (Am Council Sci Health)
Bacterial genome with DNA and RNA (J Am Chem Soc)
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187: Rounding up the bees
19 oktober 2018 · 1 uur 6 min
The TWiM people reveal that phages must cooperate to overcome CRISPR-Cas defenses, and the effect of the herbicide glyphosate on the gut microbiome of honey bees. Lees meer
Hosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt, and Michele Swanson
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Links for this episode:
Phages Cooperate to Overcome CRISPR-Cas Immunity (Cell)
Glyphosate perturbs gut microbiota of honey bees (PNAS)
Letters read on TWiM 187
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186: Crypto-metamorphosis
5 oktober 2018 · 1 uur 13 min
The TWiM team describe the involvement of a microbiome in snail metamorphosis, and using Listeria to kill tumors. Lees meer
Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson.
Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Android, RSS, or by email. Get the entire ASM Podcast Network via our Microbeworld app.
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Links for this episode
Infectious diseases after Florence (Med Inf Dis)
Cryptic niche switching in gastropod (Proc Roy Soc B)
Metamorphosis then no eating (NY Times)
Listeria promotes tumor rejection (PNAS)
Image credit
LADD pathway (jpg)
LADD (Aduro Biotech)
Crawling cells and comet tails (YouTube)
Letters read on TWiM 168
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
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185: There's no moa Moa
21 september 2018 · 1 uur 8 min
The TWiM team considers the increasing tolerance of Enterococcus to handwash alcohols, and how the study of DNA in ancient dung reveals the diet and parasite burden of extinct New Zealand birds. Lees meer
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Episode Links:
Hand sanitizer alert (Emerg Inf Dis)
Bacteria becoming hand sanitizer tolerant (NPR)
Increasing tolerance of Enterococcus to handwash alcohols (Sci Transl Med)
Coprolites and the Moa (PNAS)
After Hurricane Florence, Significant Worry Over Infectious Diseases
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
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184: CRISPR-Cas immune systems
7 september 2018 · 1 uur 26 min
Sam Sternberg discusses his work on exploring and exploiting CRISPR-Cas immune systems, beginning as a graduate student with Jennifer Doudna, at a biotech start-up, and in his laboratory at Columbia University. Lees meer
Host: Vincent Racaniello
Guest: Sam Sternberg
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Links for this episode
Sternberg Laboratory at Columbia
Mechanism of substrate selection by Cas9 (RNA)
DNA interrogation by Cas9 (Nature)
Conformational control of DNA target cleavage by Cas9 (Nature)
A Crack in Creation by Doudna and Sternberg
What if we could rewrite the human genome? (YouTube)
Sam Sternberg
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
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183: Two symbioses
23 augustus 2018 · 57 min
The TWiMpeeps discuss two symbioses: a parasitoid bacterium of a heterotrophic protist, and fungal parasites in cicadas. Lees meer
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Links for this episode:
Parasitoid bacterium of protist (bioRxiv)
Fungal symbiont recruitment in cicadas (PNAS)
Fly by virus (TWiEVO 33)
The Atlantic "How to Tame a Zombie Fungus" by Ed Yong
Image credit
Letters read on TWiM 183
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
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182: A micro story with macro implications
9 augustus 2018 · 1 uur 6 min
The TWiM hosts reveal how to test antimicrobial susceptibility in less than 30 minutes, and a carbonate-sensitive phytotransferrin in diatoms that controls iron uptake. Lees meer
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Links for this episode:
Legionnaire's Disease with Michele Swanson
Antibiotic susceptibility in less than 30 min (PNAS)
S. saprophyticus growing in microfluidic chip (movie, PNAS)
Mother machine (Jun lab)
E. coli growth in mother machine (YouTube)
Diatom phytotransferrin (Nature)
CRISPR tool kit (Nat Commun)
A Crack in Creation by Doudna and Sternberg
CRISPR/Cas9 for undergrads (BMBE)
John Oliver on gene editing (YouTube)
Image credit
Letters read on TWiM 182
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
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181: Dr. Warhol's Periodic Table of Microbes
26 juli 2018 · 58 min
Vincent speaks with John Warhol about state microbes, the Periodic Table of the Microbes, and why microbiology is cooler than astrophysics, but they have better TV shows. Lees meer
Host: Vincent Racaniello
Guest: John Warhol
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Links for this episode
State Microbe (Wikipedia)
Micro Minutes! (tumblr)
Warhol Science on Etsy
Periodic Table of Microbes (Amazon)
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180: Microbecentricity with Mark O. Martin
13 juli 2018 · 1 uur 4 min
Vincent speaks with Mark O. Martin about microbial centricity, teaching undergraduates microbiology, lux art, painting with glowing bacteria, tardigrades and much more at ASM Microbe 2018. Lees meer
Host: Vincent Racaniello
Guest: Mark O. Martin
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Links for this episode
Microbial menagerie
All creatures great and small
Carski Award
Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv
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179: Viable but not culturable
29 juni 2018 · 1 uur 16 min
The TwiModulators discuss aerosolization of bacteria and viruses in an ocean-atmosphere mesocosm, and how the common practice of decontaminating produce with chlorine produces viable but non-culturable pathogens. Lees meer
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Links for this episode:
Taxon-specific aerosolization of bacteria and viruses (Nat Commun)
Chlorine produces viable but non-culturable bacteria (mBio)
Chlorine washing fails bacteria test (Guardian)
Foodborne illness in US: Major pathogens (CDC)
Chlorine dilution calculator (Public Health Toronto)
Multistate foodborne outbreak investigations (CDC)
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178: Corals are sexy with Christina Kellogg
15 juni 2018 · 1 uur 5 min
The TWiM team travels to ASM Microbe 2018 in Atlanta, Georgia to speak with Christina Kellogg about her career and her research on coral microbial ecology. Lees meer
Hosts: Vincent Racaniello, Michael Schmidt, Elio Schaechter and Michele Swanson
Guest: Christina Kellogg
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Links for this episode:
Christina Kellogg on twitter
Coral microbial ecology
Coral reef ecosystem studies
Connectivity of vulnerable reefs
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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177: Microbial sibling conflict
1 juni 2018 · 55 min
The TWiM team discuss bacteriophage evolution in a dairy plant, and killing of less fit cells among social microbes. Lees meer
Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson, and Elio Schaechter.
Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.
Links for this episode
A decade of phage evolution (Appl Env Micr)
Animation of phage infection (Vimeo)
Double agar assay for phage (Dairy Science)
Sibling conflict among social bacteria (mBio)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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176: Elio has lots of colanic acid
18 mei 2018 · 1 uur
Vincent, Michael and Elio note the passing of Stanley Falkow, give E. coli an archaeal membrane, and show how the microbiome can make worms live longer. Lees meer
Hosts:
Vincent Racaniello, Michael Schmidt, and Elio Schaechter.
Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.
Become a patron of TWiM.
Links for this episode
Fecal transplants in the good old days (STC)
Stanley Falkow, 84
Loss of an old army buddy (STC)
Giving E. coli an archaeal membrane (PNAS)
Microbiome tunes host longevity (Cell)
Letters read on TWiM 176
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
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175: Neomycin is antiviral
2 mei 2018 · 1 uur 3 min
The TWiM team notes the passing of Allan Campbell, and explains how aminoglycoside antibiotics like neomycin enhance host resistance to viral infection. Lees meer
Hosts:
Vincent Racaniello, Michael Schmidt, and Michele Swanson.
Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.
Become a patron of TWiM.
Links for this episode:
Happy Birthday, Elio! (STC)
Allan Campbell, 88 (Stanford News)
Life in Science by Allan Campbell (Bacteriophage)
Aminoglycosides inhibit viral infection (Nat Micro)
Image credit
Letters read on TWiM 175
Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv
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174: A Gathering Typhoid Storm
19 april 2018 · 1 uur 2 min
The TWiMsters explain why untreatable typhoid fever might be on the way, and the evolution of fungal virulence in tropical frogs. Lees meer
Hosts:
Vincent Racaniello, Michael Schmidt, and Elio Schaechter.
Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.
Become a patron of TWiM.
Links for this episode
Extensively drug resistant Salmonella typhi (mBio)
A Gathering Storm (mBio)
Typhoid vaccine recommendations (CDC)
Changes in dynamics of frog fungal disease (Science)
Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv
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173: Gee whiz in style
30 maart 2018 · 59 min
The Masters of the Microbiological Universe discuss the humongouest fungus, and a commensal bacterium that protects against skin neoplasia. Lees meer
Hosts:
Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter.
Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.
Become a patron of TWiM.
Links for this episode
Fertile prototaxites (Proc Royal Soc B)
The humongousest fungus (STC)
Commensal Staphylococcus protects against skin cancer (Sci Adv)
Letters read on TWiM 173
Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv
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172: Unfolding relaxases and soil malacidins
15 maart 2018 · 1 uur 14 min
The TWiMmers discuss culture-independent discovery of malacidin antibiotics, and unfolding of relaxase during bacterial conjugation. Lees meer
Hosts:
Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter.
Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.
Become a patron of TWiM.
Links for this episode
Malacidins from soils (Nat Micro)
Excellent antibiotic resistance threat report (CDC, pdf)
Jo Handelsman on Women's History Month (CBS)
Unfolding relaxase during bacterial conjugation (J Bact)
Letters read on TWiM 172
Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv
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171: If you give a bee a fungus
22 februari 2018 · 1 uur 1 min
The TWiM team explores a stingless bee that requires a fungal steroid to pupate, and colonic biofilms containing tumorigenic bacteria in patients with colorectal polyps. Lees meer
Hosts:
Vincent Racaniello, Michael Schmidt, and Elio Schaechter.
Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.
Become a patron of TWiM.
Links for this episode
Bee larvae require fungal steroid to pupate (Sci Rep)
Biofilm refuge for tumorigenic bacteria (Science)
Letters read on TWiM 171
Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv
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170: Rats, lice, and nanoparticles
8 februari 2018 · 56 min
The TWiM team reveals that spread of plague was likely by human ectoparasites, not rats, and deconstruct a durable, broadly protective protein nanoparticle influenza virus vaccine. Lees meer
Hosts:
Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter.
Become a patron of TWiM.
Links for this episode
Ectoparasites and plague (PNAS)
SIR model for spread of disease (MAA)
Protein nanoparticle flu vaccines (Nat Commun)
Food washing (USDA)
Image credit
Letters read on TWiM 170
Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv
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169: Breatharian Bacteria
24 januari 2018 · 1 uur 2 min
The cast of TWiM reveals how uropathogenic E. coli use a copper-binding protein to treat copper as a nutrient or a toxin, and Antarctic soil bacteria that survive on trace atmospheric gases. Lees meer
Hosts:
Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter.
Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.
Become a patron of TWiM.
Links for this episode
Copper import in E. coli (Nat Chem Biol)
Conversion of OD to cells/ml for E. coli
Nutritional immunity with Jennifer Bomberger (TWiM#141)
Microbes live on atmospheric trace gases in Antarctic soil (Nature)
Antarctic terrestrial ecosystem (SciHub)
Hypolith (Wikipedia)
Breatharians (Broadly)
Image credit
Letters read on TWiM 169Letters read on TWiM 169
Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv
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TWiM #168: The lesser of two weevils
5 januari 2018 · 1 uur 17 min
Dickson joins the TWiM team to discuss the nasal microbiota of dairy farmers, and attenuation of bacterial virulence by quorum sensing in the maize weevil. Lees meer
Hosts:
Vincent Racaniello, Michael Schmidt, and Michele Swanson.
Guest: Dickson Despommier
Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.
Become a patron of TWiM.
Links for this episode:
Nasal microbiota of dairy farmers (PLoS One)
Measuring species richness, diversity, similarity (pdf one, pdf two)
Quorum sensing attenuates virulence (Cell Host Micr)
Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv
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TWiM #167: I have one word for you: Flink
22 december 2017 · 53 min
How pandemic influenza viruses suppress immunogenic cell death, and 3D printing of bacteria into functional materials.