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Join Dr Karan Rajan, medical doctor, Founder of LOAM Science and Sunday Times bestselling author as he meets the world's foremost experts in science and medicine to cut through the BS of modern health advice. One of the most-followed medical voices online, with over 10 million followers worldwide. New episodes every week.
Afleveringen
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The Biggest Lies We're Told About Supplements | Josie Porter
2 november 2026 · 45 min
Do we really need all the supplements we're being told to take? And could some of them actually be doing us more harm than good? Lees meer
In this episode I speak to specialist dietitian and GLP-1 expert Josie Porter. We discuss the science behind popular supplements, the myths around nutrition and how to get the most out of your diet. Plus, what you should know about taking GLP-1 weight loss medications.
Timestamps
(0:00) Intro - Are we taking too many supplements?
(01:40) Do we really need electrolytes for daily hydration?
(07:10) Is creatine really good for your brain?
(10:00) Can creatine make endometriosis worse?
(11:55) How to spot misleading supplement marketing
(14:40) Why taking too many vitamins can be dangerous
(17:10) The myths around prenatal supplements and folic acid
(19:20) When should you take iron supplements?
(20:40) The best foods for getting all your essential nutrients
(23:45) Can food really be medicine?
(24:55) The best foods for relieving constipation
(27:00) Why different types of fibre matter for gut health
(29:55) How to control your appetite and food cravings
(34:15) What should you eat when taking GLP-1 medications?
(38:55) How to avoid regaining weight after stopping GLP-1s
(42:30) Are GLP-1 weight loss medications really dangerous?
🦠LOAM Science
The world's first invisible fiber blend with a clinical trial! Get 10% OFF LOAM with code DRKARAN10: https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaran
📧Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity:
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📕 This Book May Save Your Life
The No.1 Sunday Times bestseller packed with evidence-based advice to improve your health.
https://geni.us/DrKaranBook
📕 This Is Vital Information
Order my new book covering everything you're too embarrassed to ask your doctor but really should.
https://linktr.ee/ThisisVi…
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We’ve Got Testosterone Completely Wrong | Dr Channa Jayasena
26 oktober 2026 · 42 min
Do we really need to be so worried about our testosterone levels? And is it really the solution to all of our health problems? Lees meer
In this episode I speak to reproductive health specialist Dr Channa Jayasena. We discuss testosterone, the myths around it and the latest in reproductive science!
Timestamps
(0:00) Intro - Are we really facing a low testosterone crisis?
(02:35) Why testosterone prescriptions have increased by 135%
(08:17) What your testosterone levels reveal about your overall health
(12:04) Testosterone, masculinity and the male body image crisis
(17:56) What are the real symptoms of low testosterone?
(21:26) Should healthy men get their testosterone tested?
(23:05) Does testosterone really decline as we age?
(26:25) What other factors can lower testosterone?
(30:31) Does testosterone replacement therapy mask underlying health problems?
(34:53) The dangers of peptides and hormone cocktails
(36:12) Can you naturally boost your testosterone?
(38:31) The health risks of taking testosterone you don't need
(40:06) Why testosterone levels don't tell you about sperm health
🦠LOAM Science
The world's first invisible fiber blend with a clinical trial! Get 10% OFF LOAM with code DRKARAN10: https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaran
📧Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity:
https://drkaran.kit.com/subscribe
📕 This Book May Save Your Life
The No.1 Sunday Times bestseller packed with evidence-based advice to improve your health.
https://geni.us/DrKaranBook
📕 This Is Vital Information
Order my new book covering everything you're too embarrassed to ask your doctor but really should.
https://linktr.ee/ThisisVitalInformation
🤖 Dr Karan's Digital Twin
Ask my AI twin your health questions anytime.
http://DrKaran.ai
About Dr Karan:
Dr. Karan Rajan is a doctor, author, Founder of LOAM Scienc…
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The Hidden Link Between Menopause And Gut Health | Cynthia Thurlow
19 oktober 2026 · 42 min
What role does gut health have to play in the menopause? Lees meer
In this episode I speak to Cynthia Thurlow, author of The Menopause Gut, who explains how a woman’s microbiome shifts during menopause - and why understanding this can dramatically improve health outcomes.
Timestamps
(0:00) Intro - Why gut health becomes so important during the menopause
(05:16) Why menopause feels like accelerated aging
(13:34) The role of fibre in managing changing hormones
(20:45) Understanding the estrobolome
(26:44) Are we missing a whole treatment avenue for perimenopause?
(31:04) Common gut signs when going through perimenopause
(33:31) The gut-brain axis and its impact on anxiety and brain fog
(36:42) Does menopause gut advice differ from normal gut advice?
🦠LOAM Science
The world's first invisible fiber blend with a clinical trial! Get 10% OFF LOAM with code DRKARAN10: https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaran
📧Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity:
https://drkaran.kit.com/subscribe
📕 This Book May Save Your Life
The No.1 Sunday Times bestseller packed with evidence-based advice to improve your health.
https://geni.us/DrKaranBook
📕 This Is Vital Information
Order my new book covering everything you're too embarrassed to ask your doctor but really should.
https://linktr.ee/ThisisVitalInformation
🤖 Dr Karan's Digital Twin
Ask my AI twin your health questions anytime.
http://DrKaran.ai
About Dr Karan:
Dr. Karan Rajan is a doctor, author, Founder of LOAM Science and Chief of Science at Throne Science, dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor.
📱Connect with me:
Instagram: https://www.instagram.com/…
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Are Microplastics Really Making Us Sick? | Dr Stephanie Wright
12 oktober 2026 · 39 min
Microplastics are everywhere - in the food we eat, the air we breathe, and the environment around us. But how much do we actually know about what they are doing inside the human body? Lees meer
In this episode I speak to microplastics researcher Dr Stephanie Wright to discuss everything from the difference between micro and nanoplastics, how particles interact with cells and the immune system and how researchers even measure plastic in blood and tissues.
Timestamps
(0:00) Intro - Are microplastics actually harming us?
(0:51) What do we actually know about the health effects?
(2:00) What animal studies can - and can't - tell us
(4:16) Should we be more concerned about nanoplastics?
(5:52) How could microplastics cause harm inside the body?
(7:50) Microplastics, the gut and the immune system
(9:03) How do we measure microplastics in the body?
(12:06) Microplastics in the brain - what was wrong with the research?
(14:19) How much microplastic are we actually exposed to?
(15:40) Can microplastics be removed from the body?
(17:01) The biggest sources: heating plastic, tea bags and tyre wear
(19:16) Which foods contain the most microplastics?
(20:37) Can plants absorb nanoplastics from soil?
(21:45) Microplastics in the placenta and fetus
(24:00) Will microplastics accumulate as we age?
(25:50) Are we blaming microplastics for too many health problems?
(27:00) The 'exposome' - why your whole environment matters
(30:58) How dangerous are microplastics compared with other pollutants?
(32:14) Can fibre help remove microplastics?
(38:50) What we still don't know about microplastics
🦠LOAM Science
The world's first invisible fiber blend with a clinical trial! Get 10% OFF LOAM with code DRKARAN10: https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaran
📧Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity:
https://drkaran.kit.com/…
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The Real Reason You Can't Lose Weight - And How To Fix It | Dr. Simon Cork
5 oktober 2026 · 38 min
Why does your body fight so hard to keep you at the same weight - even if it’s an unhealthy weight? Lees meer
In this episode I speak to Dr. Simon Cork, an expert in appetite and gut hormone physiology at Anglia Ruskin University. He explains why our hormones trick our body into weight gain and what GLP-1 medications actually do to your gut and brain.
Timestamps
(0:00) Intro - Why it’s so tough to shift our weight from baseline
(3:14) If weight “set points” exist, why is everyone gaining weight?
(5:22) What leptin is really doing for your hunger
(8:31) The gut-brain axis and the role of the vagus nerve
(10:31) How long does it take to know you’re full from eating?
(14:01) Can you resensitise your leptin signals?
(17:11) Does vagus nerve stimulation work to reduce hunger?
(19:24) Can you maintain the effects of GLP-1s without taking them forever?
(23:23) Can GLP-1s be used effectively outside of weight loss?
(31:43) Why some people are non-responders to GLP-1s
🦠LOAM Science
The world's first invisible fiber blend with a clinical trial! Get 10% OFF LOAM with code DRKARAN10: https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaran
📧Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity:
https://drkaran.kit.com/subscribe
📕 This Book May Save Your Life
The No.1 Sunday Times bestseller packed with evidence-based advice to improve your health.
https://geni.us/DrKaranBook
📕 This Is Vital Information
Order my new book covering everything you're too embarrassed to ask your doctor but really should.
https://linktr.ee/ThisisVitalInformation
🤖 Dr Karan's Digital Twin
Ask my AI twin your health questions anytime.
http://DrKaran.ai
About Dr Karan:
Dr. Karan Rajan is a doctor, author, Founder of LOAM Science and Chief of Science at Throne Science, dedicated to making health and medical science accessible to all. Through evidence-based …
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He Got Cancer - And The Misinformation Made Him Furious | Jamie East
28 september 2026 · 42 min
When broadcaster Jamie East got diagnosed with leukemia, he documented his whole journey and made a podcast about it. During his search for answers he discovered a world of horrendous cancer misinformation - and it made him furious. Lees meer
In this episode Jamie talks about his cancer journey in a frank and honest way - the subject of his new podcast ‘Bad Blood’.
Timestamps
(0:00) Intro - When Jamie found out he had leukemia
(2:05) The symptoms
(7:00) How it feels for doctors delivering bad news
(11:48) Why leukemia symptoms go unnoticed
(14:04) Should you use Google to look up your diagnosis?
(18:01) The misinformation Jamie discovered
(23:02) The tricks grifters use to spread misinformation
(26:46) The sugar and cancer myth
(29:49) Why we need to stop blaming cancer patients
(32:08) The “fighting” language around cancer
(36:33) How some cancer drugs impact your life
🦠LOAM Science
The world's first invisible fiber blend with a clinical trial! Get 10% OFF LOAM with code DRKARAN10: https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaran
📧Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity:
https://drkaran.kit.com/subscribe
📕 This Book May Save Your Life
The No.1 Sunday Times bestseller packed with evidence-based advice to improve your health.
https://geni.us/DrKaranBook
📕 This Is Vital Information
Order my new book covering everything you're too embarrassed to ask your doctor but really should.
https://linktr.ee/ThisisVitalInformation
🤖 Dr Karan's Digital Twin
Ask my AI twin your health questions anytime.
http://DrKaran.ai
About Dr Karan:
Dr. Karan Rajan is a doctor, author, Founder of LOAM Science and Chief of Science at Throne Science, dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choi…
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The Dangerous Invisible Fat You’re Not Paying Attention To | Prof. Jimmy Bell
21 september 2026 · 47 min
Most of us only pay attention to the fat around our bellies or our hips, but there’s a hidden fat we’re just ignoring. You can’t see visceral fat, but too much of it is dangerous - even slim people can have harmful levels without even knowing. Lees meer
In this episode I speak to visceral fat expert Professor Jimmy Bell to find out what it’s doing in our bodies when there’s too much - and why you shouldn’t be worrying about weight if you want to stay healthy.
Timestamps
(0:00) Intro - The role of fat in your body
(4:16) Why fat is actually a good thing
(8:18) Visceral fat vs subcutaneous fat
(11:37) Thin on the outside - fat on the inside
(19:43) Why you shouldn’t chase scale weight
(22:28) Differences between where men and women store fat
(27:25) Do genetics affect baseline levels of visceral fat?
(32:25) How weight loss injections are impacting visceral fat
(37:03) The role of fast food in visceral fat accumulation
(42:31) Is the gut linked to fat gain?
(44:18) What should you do to reduce visceral fat?
🦠LOAM Science
The world's first invisible fiber blend with a clinical trial! Get 10% OFF LOAM with code DRKARAN10: https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaran
📧Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity:
https://drkaran.kit.com/subscribe
📕 This Book May Save Your Life
The No.1 Sunday Times bestseller packed with evidence-based advice to improve your health.
https://geni.us/DrKaranBook
📕 This Is Vital Information
Order my new book covering everything you're too embarrassed to ask your doctor but really should.
https://linktr.ee/ThisisVitalInformation
🤖 Dr Karan's Digital Twin
Ask my AI twin your health questions anytime.
http://DrKaran.ai
About Dr Karan:
Dr. Karan Rajan is a doctor, author, Founder of LOAM Science and Chief of Science at Throne Science, dedicated to making health and medical sc…
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How Worried Should We Be About Glyphosate? | Michael Antoniou
14 september 2026 · 39 min
How worried should we really be about glyphosate? There’s growing fear that the world’s most popular weed killer is causing everything from cancer to gut problems. But is the evidence clear enough? Lees meer
In this episode I speak to Professor Michael Antoniou, who explains what he’s discovered by studying the health effects of glyphosate exposure - particularly within commercial formulations.
Timestamps
(0:00) Intro - The growing fear around glyphosate
(0:42) What is glyphosate and how does it work?
(5:53) The link between glyphosate and GMOs
(7:42) The microbiome impact
(11:48) Does the fear match reality?
(19:55) Why did regulators conclude it was safe?
(22:07) Why we should test commercial formulations
(25:34) Why microbiome work is still early stage
(28:30) Do some foods carry more glyphosate?
(30:00) Is glyphosate responsible for a reduction in soil quality?
(34:03) Why we still need more human data
🦠LOAM Science
The world's first invisible fiber blend with a clinical trial! Get 10% OFF LOAM with code DRKARAN10: https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaran
🚽 Throne Science
Discover the world’s first continuous tracker for getting personalized insight about gut health, hydration, and prostate health with every flush.
Get $80 off with code DRKARAN:
https://thronescience.com/?utm_source=karan&utm_medium=youtube
📧Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity:
https://drkaran.kit.com/subscribe
📕 This Book May Save Your Life
The No.1 Sunday Times bestseller packed with evidence-based advice to improve your health.
https://geni.us/DrKaranBook
📕 This Is Vital Information
Order my new book covering everything you're too embarrassed to ask your doctor but really should.
https://linktr.ee/ThisisVitalInformation
🤖 Dr Karan's Digital Twin
Ask my AI twin your health questions anytime.
http://DrKaran.ai
… -
Fatty Liver Expert: Your Liver Could Be In Trouble | Dr. Vishal Patel
7 september 2026 · 46 min
Fatty liver disease affects a massive 1 in 3 people, yet most of us don’t even realise we have it - until it’s too late. But it is reversible. I know, because I’ve done it myself. Lees meer
In this episode I speak to Dr Vishal Patel, Consultant Hepatologist & Endoscopist at the Liver Unit, King's College Hospital. He breaks down the surprising impact of liver health on your whole body, warning signs that something’s wrong - and how to protect your liver.
Timestamps
(0:00) Intro - Why you need to rethink liver health
(3:05) What impact does the liver have throughout the body?
(5:37) How Dr Karan discovered he had fatty liver disease
(11:09) How long do you have to address fatty liver disease?
(16:25) How weight loss makes the biggest difference
(19:21) How food can increase liver function
(22:46) Why fibre recommendations are still not enough
(25:17) Why some supplements can make liver health worse
(31:15) Are there signs your liver health isn’t good?
(36:06) How much can your liver actually process?
(39:34) How liver health links to oral health and the gut microbiome
🦠LOAM Science
The world's first invisible fiber blend with a clinical trial! Get 10% OFF LOAM with code DRKARAN10: https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaran
🚽 Throne Science
Discover the world’s first continuous tracker for getting personalized insight about gut health, hydration, and prostate health with every flush.
Get $80 off with code DRKARAN:
https://thronescience.com/?utm_source=karan&utm_medium=youtube
📧Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity:
https://drkaran.kit.com/subscribe
📕 This Book May Save Your Life
The No.1 Sunday Times bestseller packed with evidence-based advice to improve your health.
https://geni.us/DrKaranBook
📕 This Is Vital Information
Order my new book covering everything you're too embarrassed to ask yo…
-
The Everyday Items Exposing You to Microplastics | Dana Zhaxylykova
31 augustus 2026 · 35 min
Microplastics are everywhere - in the food we eat, the water we drink, and even the air we breathe. Increasingly, we hear about the dangers of these tiny particles - but what happens when they make their way into our bodies; and what could it mean for our health, and the environment? Lees meer
In this episode I speak to microplastics researcher Dana Zhaxylykova, to discover what we should know about micro and nanoplastics, and their effects on the human body and world as a whole - where we’re exposed to them, how the food chain and environment is impacted, and how they may interact with our cells, organs and immune system. We explore what the science tells us so far, what remains uncertain, and whether there are practical steps we can take to reduce our exposure.
Timestamps
(0:00) Intro - What are microplastics?
(1:22) Why are we hearing so much about microplastics now?
(3:06) Environmental worries of plastic pollution
(7:40) Human health impacts
(8:57) The “credit card-sized” ingestion estimate
(9:34) The main culprits of exposure to microplastics
(12:29) How harm from micro and nano plastics occurs
(15:59) Can microplastics be removed from the body?
(18:30) Research into health effects
(19:45) Impacts of microplastics on the gut
(21:28) How will microplastics shape the planet going forward?
(22:12) How tardigrades are immune and use microplastics to travel
(23:25) How could enzymes and probiotics help?
(26:25) Are particular areas of the world disproportionately affected?
(29:09) What regulations and controls are there?
(32:22) Top tips for people to reduce microplastic burden
🦠LOAM Science
The world's first invisible fiber blend with a clinical trial! Get 10% OFF LOAM with code DRKARAN10: https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaran
🚽 Throne Science
Discover the world’s first continuous tracker for getting personalized insight about gut health, hydration, and prostate health w…
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